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A communal catalogue reveals Earth’s multiscale microbial diversity
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(2017) A communal catalogue reveals Earth’s multiscale microbial diversity. Nature . doi:10.1038/nature24621 ISSN 0028-0836.
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Official URL: http://dx.doi.org/10.1038/nature24621
Abstract
Our growing awareness of the microbial world’s importance and diversity contrasts starkly with our limited understanding of its fundamental structure. Despite recent advances in DNA sequencing, a lack of standardized protocols and common analytical frameworks impedes comparisons among studies, hindering the development of global inferences about microbial life on Earth. Here we present a meta-analysis of microbial community samples collected by hundreds of researchers for the Earth Microbiome Project. Coordinated protocols and new analytical methods, particularly the use of exact sequences instead of clustered operational taxonomic units, enable bacterial and archaeal ribosomal RNA gene sequences to be followed across multiple studies and allow us to explore patterns of diversity at an unprecedented scale. The result is both a reference database giving global context to DNA sequence data and a framework for incorporating data from future studies, fostering increasingly complete characterization of Earth’s microbial diversity.
Item Type: | Journal Article | ||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||
Journal or Publication Title: | Nature | ||||||
Publisher: | Nature Publishing | ||||||
ISSN: | 0028-0836 | ||||||
Official Date: | 1 November 2017 | ||||||
Dates: |
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DOI: | 10.1038/nature24621 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||
Date of first compliant deposit: | 18 October 2018 | ||||||
Date of first compliant Open Access: | 18 October 2018 |
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