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Do cryptic reservoirs threaten Gambiense-sleeping sickness elimination?
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(2018) Do cryptic reservoirs threaten Gambiense-sleeping sickness elimination? Trends in Parasitology, 34 (3). pp. 197-207. doi:10.1016/j.pt.2017.11.008 ISSN 1471-4922.
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Official URL: http://dx.doi.org/10.1016/j.pt.2017.11.008
Abstract
Trypanosoma brucei gambiense causes human African trypanosomiasis (HAT). Between 1990 and 2015, almost 440 000 cases were reported. Large-scale screening of populations at risk, drug donations, and efforts by national and international stakeholders have brought the epidemic under control with <2200 cases in 2016. The World Health Organization (WHO) has set the goals of gambiense-HAT elimination as a public health problem for 2020, and of interruption of transmission to humans for 2030. Latent human infections and possible animal reservoirs may challenge these goals. It remains largely unknown whether, and to what extend, they have an impact on gambiense-HAT transmission. We argue that a better understanding of the contribution of human and putative animal reservoirs to gambiense-HAT epidemiology is mandatory to inform elimination strategies.
Item Type: | Journal Article | ||||||||||||||||||
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Subjects: | R Medicine > RC Internal medicine | ||||||||||||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||||||||||||||||
Library of Congress Subject Headings (LCSH): | African trypanosomiasis -- Prevention, Trypanosoma brucei | ||||||||||||||||||
Journal or Publication Title: | Trends in Parasitology | ||||||||||||||||||
Publisher: | Elsevier Science | ||||||||||||||||||
ISSN: | 1471-4922 | ||||||||||||||||||
Official Date: | 1 March 2018 | ||||||||||||||||||
Dates: |
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Volume: | 34 | ||||||||||||||||||
Number: | 3 | ||||||||||||||||||
Page Range: | pp. 197-207 | ||||||||||||||||||
DOI: | 10.1016/j.pt.2017.11.008 | ||||||||||||||||||
Status: | Peer Reviewed | ||||||||||||||||||
Publication Status: | Published | ||||||||||||||||||
Access rights to Published version: | Restricted or Subscription Access | ||||||||||||||||||
Date of first compliant deposit: | 24 January 2018 | ||||||||||||||||||
Date of first compliant Open Access: | 23 January 2019 | ||||||||||||||||||
RIOXX Funder/Project Grant: |
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