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Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis

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UNSPECIFIED (2003) Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis. NATURAL PRODUCT REPORTS, 20 (2). pp. 252-273. ISSN 0265-0568

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Official URL: http://dx.doi.org/10.1039/b202149h

Abstract

The biosynthesis of peptidoglycan is essential for all bacteria and has no counterpart in eukaryotic cells. It is one of the prime targets for antibiotic chemotherapy, especially phospho-MurNAc-pentapeptide translocase (translocase I) is a fascinating target in which there is no commercial antibiotic. In this review we will describe three nucleoside translocase I inhibitors, mureidomycin, tunicamycin and liposidomycin.

Item Type: Journal Item
Subjects: Q Science > QD Chemistry
Journal or Publication Title: NATURAL PRODUCT REPORTS
Publisher: ROYAL SOC CHEMISTRY
ISSN: 0265-0568
Date: April 2003
Volume: 20
Number: 2
Number of Pages: 22
Page Range: pp. 252-273
Identification Number: 10.1039/b202149h
Publication Status: Published
URI: http://wrap.warwick.ac.uk/id/eprint/9827

Data sourced from Thomson Reuters' Web of Knowledge

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