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Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis
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UNSPECIFIED (2003) Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis. NATURAL PRODUCT REPORTS, 20 (2). pp. 252-273. ISSN 0265-0568
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Official URL: http://dx.doi.org/10.1039/b202149h
Abstract
The biosynthesis of peptidoglycan is essential for all bacteria and has no counterpart in eukaryotic cells. It is one of the prime targets for antibiotic chemotherapy, especially phospho-MurNAc-pentapeptide translocase (translocase I) is a fascinating target in which there is no commercial antibiotic. In this review we will describe three nucleoside translocase I inhibitors, mureidomycin, tunicamycin and liposidomycin.
| Item Type: | Journal Item |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Journal or Publication Title: | NATURAL PRODUCT REPORTS |
| Publisher: | ROYAL SOC CHEMISTRY |
| ISSN: | 0265-0568 |
| Date: | April 2003 |
| Volume: | 20 |
| Number: | 2 |
| Number of Pages: | 22 |
| Page Range: | pp. 252-273 |
| Identification Number: | 10.1039/b202149h |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/9827 |
Data sourced from Thomson Reuters' Web of Knowledge
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