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A comparison of the cost-effectiveness of intramedullary nail fixation and locking plate fixation in the treatment of adult patients with an extra-articular fracture of the distal tibia
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FixDT trial investigators (Including: Maredza, Mandy, Petrou, Stavros, Dritsaki, M., Achten, Juul, Griffin, James M., Lamb, S. E. (Sallie E.), Parsons, Nicholas R. and Costa, Matthew L.). (2018) A comparison of the cost-effectiveness of intramedullary nail fixation and locking plate fixation in the treatment of adult patients with an extra-articular fracture of the distal tibia. The Bone & Joint Journal, 100-B (5). pp. 624-633. doi:10.1302/0301-620X.100B5.BJJ-2017-1329.R2
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WRAP-Cost-effectiveness-intramedullary-nail-fixation-versus-locking-plate-Petrou-2018.pdf - Accepted Version - Requires a PDF viewer. Download (889Kb) | Preview |
Official URL: https://doi.org/10.1302/0301-620X.100B5.BJJ-2017-1...
Abstract
Aim
The aim of this study was to compare the cost-effectiveness of intramedullary nail fixation and ‘locking’ plate fixation in the treatment of extra-articular fractures of the distal tibia.
Patients and Methods
An economic evaluation was conducted from the perspective of the United Kingdom National Health Service (NHS) and personal social services (PSS), based on evidence from the Fixation of Distal Tibia Fractures (UK FixDT) multicentre parallel trial. Data from 321 patients were available for analysis. Costs were collected prospectively over the 12-month follow-up period using trial case report forms and participant-completed questionnaires. Cost-effectiveness was reported in terms of incremental cost per quality adjusted life year (QALY) gained, and net monetary benefit. Sensitivity analyses were conducted to test the robustness of cost-effectiveness estimates.
Results
Mean NHS and PSS costs were significantly lower for patients treated with an intramedullary nail than for those treated with a locking plate (-£970, 95% confidence interval (CI) -1685 to -256; p = 0.05). There was a small increase in QALYs gained in the nail fixation group (0.01, 95% CI -0.03 to 0.06; p = 0.52). The probability of cost-effectiveness for nail fixation exceeded 90% at cost-effectiveness thresholds as low as £15 000 per additional QALY. The cost-effectiveness results remained robust to several sensitivity analyses.
Conclusion
This trial-based economic evaluation suggests that nail fixation is a cost-effective alternative to locking plate fixation.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > RD Surgery | ||||||||
| Divisions: | Faculty of Medicine > Warwick Medical School | ||||||||
| Library of Congress Subject Headings (LCSH): | Intramedullary fracture fixation, Tibia -- Fracture -- Treatment | ||||||||
| Journal or Publication Title: | The Bone & Joint Journal | ||||||||
| Publisher: | British Editorial Society of Bone and Joint Surgery | ||||||||
| ISSN: | 2049-4394 | ||||||||
| Official Date: | May 2018 | ||||||||
| Dates: |
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| Volume: | 100-B | ||||||||
| Number: | 5 | ||||||||
| Page Range: | pp. 624-633 | ||||||||
| DOI: | 10.1302/0301-620X.100B5.BJJ-2017-1329.R2 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||
| RIOXX Funder/Project Grant: |
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