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Core Outcome Set for Cardiac Arrest (COSCA) in adults : an advisory statement from the International Liaison Committee on Resuscitation
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COSCA Collaborators (Including:
). (2018) Core Outcome Set for Cardiac Arrest (COSCA) in adults : an advisory statement from the International Liaison Committee on Resuscitation. Resuscitation, 127 . pp. 147-163. doi:10.1016/j.resuscitation.2018.03.022 ISSN 0300-9572.
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WRAP-COSCA-adults-advisory-statement-International-Liaison-Committee-Resuscitation-Perkins-2018.pdf - Accepted Version - Requires a PDF viewer. Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0. Download (1806Kb) | Preview |
Official URL: https://doi.org/10.1016/j.resuscitation.2018.03.02...
Abstract
Cardiac arrest effectiveness trials have traditionally reported outcomes that focus on survival. A lack of consistency in outcome reporting between trials limits the opportunities to pool results for meta-analysis. The COSCA initiative (Core Outcome Set for Cardiac Arrest), a partnership between patients, their partners, clinicians, research scientists, and the International Liaison Committee on Resuscitation, sought to develop a consensus core outcome set for cardiac arrest for effectiveness trials. Core outcome sets are primarily intended for large, randomised clinical effectiveness trials (sometimes referred to as pragmatic trials or phase III/IV trials) rather than for pilot or efficacy studies. A systematic review of the literature combined with qualitative interviews among cardiac arrest survivors was used to generate a list of potential outcome domains. This list was prioritised through a Delphi process, which involved clinicians, patients, and their relatives/partners. An international advisory panel narrowed these down to 3 core domains by debate that led to consensus. The writing group refined recommendations for when these outcomes should be measured and further characterised relevant measurement tools. Consensus emerged that a core outcome set for reporting on effectiveness studies of cardiac arrest (COSCA) in adults should include survival, neurological function, and health-related quality of life. This should be reported as survival status and modified Rankin scale score at hospital discharge, at 30 days, or both. Health-related quality of life should be measured with ≥1 tools from Health Utilities Index version 3, Short-Form 36-Item Health Survey, and EuroQol 5D-5L at 90 days and at periodic intervals up to 1 year after cardiac arrest, if resources allow.
Item Type: | Journal Article | ||||||||||||||||||||||||
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Subjects: | R Medicine > RC Internal medicine | ||||||||||||||||||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Cardiac arrest, Quality of life -- Health aspects -- Statistics | ||||||||||||||||||||||||
Journal or Publication Title: | Resuscitation | ||||||||||||||||||||||||
Publisher: | Elsevier Ireland Ltd | ||||||||||||||||||||||||
ISSN: | 0300-9572 | ||||||||||||||||||||||||
Official Date: | 1 June 2018 | ||||||||||||||||||||||||
Dates: |
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Volume: | 127 | ||||||||||||||||||||||||
Page Range: | pp. 147-163 | ||||||||||||||||||||||||
DOI: | 10.1016/j.resuscitation.2018.03.022 | ||||||||||||||||||||||||
Status: | Peer Reviewed | ||||||||||||||||||||||||
Publication Status: | Published | ||||||||||||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||||||||||||||||||
Copyright Holders: | European Resuscitation Council and American Heart Association, Inc. | ||||||||||||||||||||||||
Date of first compliant deposit: | 9 February 2018 | ||||||||||||||||||||||||
Date of first compliant Open Access: | 29 April 2019 | ||||||||||||||||||||||||
RIOXX Funder/Project Grant: |
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Version or Related Resource: | http://wrap.warwick.ac.uk/101696 |
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