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Palladium-polymer nanoreactors for the aqueous asymmetric synthesis of therapeutic flavonoids
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Lestini, E., Blackman, Lewis D., Zammit, Charlotte M., Chen, T., Williams, R. J., Inam, Maria, Couturaud, Benoit and O'Reilly, Rachel K. (2018) Palladium-polymer nanoreactors for the aqueous asymmetric synthesis of therapeutic flavonoids. Polymer Chemistry, 9 (7). pp. 820-823. doi:10.1039/c7py02050c
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Official URL: http://doi.org/10.1039/c7py02050c
Abstract
Polymeric core–shell micelles incorporating a chiral palladium pyridinooxazoline catalyst are presented as nanoreactors for the aqueous asymmetric synthesis of flavanones, a class of flavonoids with therapeutic properties. Use of the nanoreactor was found to increase catalyst activity, enabling catalysis at room temperature, with low palladium loadings and without any additives.
| Item Type: | Journal Article | ||||||
|---|---|---|---|---|---|---|---|
| Divisions: | Faculty of Science > Chemistry | ||||||
| SWORD Depositor: | Library Publications Router | ||||||
| Journal or Publication Title: | Polymer Chemistry | ||||||
| Publisher: | Royal Society of Chemistry (RSC) | ||||||
| ISSN: | 1759-9962 | ||||||
| Official Date: | 30 January 2018 | ||||||
| Dates: |
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| Volume: | 9 | ||||||
| Number: | 7 | ||||||
| Page Range: | pp. 820-823 | ||||||
| DOI: | 10.1039/c7py02050c | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Publisher Statement: | ** From Crossref via Jisc Publications Router. | ||||||
| Access rights to Published version: | Restricted or Subscription Access |
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