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Palladium-polymer nanoreactors for the aqueous asymmetric synthesis of therapeutic flavonoids

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Lestini, E., Blackman, Lewis D., Zammit, Charlotte M., Chen, T., Williams, R. J., Inam, Maria, Couturaud, Benoit and O'Reilly, Rachel K. (2018) Palladium-polymer nanoreactors for the aqueous asymmetric synthesis of therapeutic flavonoids. Polymer Chemistry, 9 (7). pp. 820-823. doi:10.1039/c7py02050c

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Official URL: http://doi.org/10.1039/c7py02050c

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Abstract

Polymeric core–shell micelles incorporating a chiral palladium pyridinooxazoline catalyst are presented as nanoreactors for the aqueous asymmetric synthesis of flavanones, a class of flavonoids with therapeutic properties. Use of the nanoreactor was found to increase catalyst activity, enabling catalysis at room temperature, with low palladium loadings and without any additives.

Item Type: Journal Article
Divisions: Faculty of Science, Engineering and Medicine > Science > Chemistry
SWORD Depositor: Library Publications Router
Journal or Publication Title: Polymer Chemistry
Publisher: Royal Society of Chemistry (RSC)
ISSN: 1759-9962
Official Date: 30 January 2018
Dates:
DateEvent
30 January 2018Published
18 January 2018Accepted
Volume: 9
Number: 7
Page Range: pp. 820-823
DOI: 10.1039/c7py02050c
Status: Peer Reviewed
Publication Status: Published
Reuse Statement (publisher, data, author rights): ** From Crossref via Jisc Publications Router.
Access rights to Published version: Restricted or Subscription Access

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