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Root mean square error of neural spike train sequence matching with optogenetics
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Noel, Adam, Makrakis, Dimitrios and Eckford, Andrew W. (2017) Root mean square error of neural spike train sequence matching with optogenetics. In: 2017 IEEE Global Communications Conference GLOBECOM 2017 , Singapore, Singapore, 4-8 Dec. 2017. Published in: 2017 IEEE Global Communications Conference GLOBECOM 2017 pp. 1-6. ISBN 9781509050192. doi:10.1109/GLOCOM.2017.8255060
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Official URL: http://dx.doi.org/10.1109/GLOCOM.2017.8255060
Abstract
Optogenetics is an emerging field of neuroscience where neurons are genetically modified to express light-sensitive receptors that enable external control over when the neurons fire. Given the prominence of neuronal signaling within the brain and throughout the body, optogenetics has significant potential to improve the understanding of the nervous system and to develop treatments for neurological diseases. This paper uses a simple optogenetic model to compare the timing distortion between a randomly-generated target spike sequence and an externally-stimulated neuron spike sequence. The distortion is measured by filtering each sequence and finding the root mean square error between the two filter outputs. The expected distortion is derived in closed form when the target sequence generation rate is sufficiently low. Derivations are verified via simulations.
| Item Type: | Conference Item (Paper) | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||
| Journal or Publication Title: | 2017 IEEE Global Communications Conference GLOBECOM 2017 | ||||
| Publisher: | IEEE | ||||
| ISBN: | 9781509050192 | ||||
| Book Title: | GLOBECOM 2017 - 2017 IEEE Global Communications Conference | ||||
| Official Date: | 2017 | ||||
| Dates: |
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| Page Range: | pp. 1-6 | ||||
| DOI: | 10.1109/GLOCOM.2017.8255060 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Conference Paper Type: | Paper | ||||
| Title of Event: | 2017 IEEE Global Communications Conference GLOBECOM 2017 | ||||
| Type of Event: | Conference | ||||
| Location of Event: | Singapore, Singapore | ||||
| Date(s) of Event: | 4-8 Dec. 2017 |
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