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A novel dizinc bridged hydroxamate model for hydroxamate inhibited zinc hydrolases
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UNSPECIFIED (2002) A novel dizinc bridged hydroxamate model for hydroxamate inhibited zinc hydrolases. CHEMICAL COMMUNICATIONS (11). pp. 1210-1211. doi:10.1039/b202612k ISSN 1359-7345.
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Official URL: http://dx.doi.org/10.1039/b202612k
Abstract
Reaction of Zn(OAc)(2).2H(2)O with tmen leads to the formation of [Zn(tmen)(OAc)(2)] (I) which reacts with benzohydroxamic acid to form Zn(BA)(2).H2O (II) and the novel dizinc hydroxamate bridged complex [Zn-2(mu-OAc)(2)(OAc)(2)-(mu-BA)(tmen)](III), which may also be prepared by self-assembly and whose structure closely mimics that of the native hydroxamate inhibited Aeromonas proteolytica aminopeptidase.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Journal or Publication Title: | CHEMICAL COMMUNICATIONS | ||||
Publisher: | ROYAL SOC CHEMISTRY | ||||
ISSN: | 1359-7345 | ||||
Official Date: | 2002 | ||||
Dates: |
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Number: | 11 | ||||
Number of Pages: | 2 | ||||
Page Range: | pp. 1210-1211 | ||||
DOI: | 10.1039/b202612k | ||||
Publication Status: | Published |
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