The Library
Optimal allocation of building blocks between nutrient uptake systems in a microbe
Tools
UNSPECIFIED (2002) Optimal allocation of building blocks between nutrient uptake systems in a microbe. JOURNAL OF MATHEMATICAL BIOLOGY, 44 (3). pp. 276-296. doi:10.1007/s002850100123 ISSN 0303-6812.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1007/s002850100123
Abstract
A bacterial cell must distribute its molecular building, blocks among various types of nutrient uptake systems. If the microbe is to maximize its average growth rate, this allocation of building blocks must be adjusted to the environmental availabilities of the various nutrients. The adjustments can be found front growth balancing considerations. We give a full proof of optimality and uniqueness of the optimal allocation regime for multiple model of microbial growth and internal stores kinetics. This proof suggests likely candidates for optimal control regimes in the case of a snore realistic model. These candidate regimes differ with respect to the information that the cell's control system must have access to. We pay particular attention to one of the three candidates. a feedback regime based on a cellular control system that monitors only internal reserve densities. We show that allocation converges rapidly to balanced growth under this control regime.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QH Natural history > QH301 Biology | ||||
Journal or Publication Title: | JOURNAL OF MATHEMATICAL BIOLOGY | ||||
Publisher: | SPRINGER-VERLAG | ||||
ISSN: | 0303-6812 | ||||
Official Date: | March 2002 | ||||
Dates: |
|
||||
Volume: | 44 | ||||
Number: | 3 | ||||
Number of Pages: | 21 | ||||
Page Range: | pp. 276-296 | ||||
DOI: | 10.1007/s002850100123 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |