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Electrospray mass spectrometry of angiotensin-converting enzyme inhibitors
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UNSPECIFIED (1998) Electrospray mass spectrometry of angiotensin-converting enzyme inhibitors. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 12 (23). pp. 1928-1932. ISSN 0951-4198.
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Abstract
Electrospray ionisation (ESI) mass spectrometry combined with collision-induced decomposition of ions given by captopril, lisinopril and enalaprilat, angiotensin-converting enzyme (ACE) inhibitors, has been used to characterise these compounds. As expected, the ESI mass spectra are characterised by the presence of abundant [M + H](+) ions with very little fragmentation at low cone voltages. Fragment ions are produced by collision-induced decomposition of these ions at higher cone voltages, and in MS/MS experiments. Fragmentation pathways and structures of fragment ions observed have been proposed. (C) 1998 John Wiley & Sons, Ltd.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry Q Science > QC Physics |
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Journal or Publication Title: | RAPID COMMUNICATIONS IN MASS SPECTROMETRY | ||||
Publisher: | JOHN WILEY & SONS LTD | ||||
ISSN: | 0951-4198 | ||||
Official Date: | 1998 | ||||
Dates: |
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Volume: | 12 | ||||
Number: | 23 | ||||
Number of Pages: | 5 | ||||
Page Range: | pp. 1928-1932 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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