The Library
A PLEIOTROPIC REDUCED VIRULENCE (RVI-) MUTANT OF ERWINIA-CAROTOVORA SUBSPECIES ATROSEPTICA IS DEFECTIVE IN FLAGELLA ASSEMBLY PROTEINS THAT ARE CONSERVED IN PLANT AND ANIMAL BACTERIAL PATHOGENS
Tools
UNSPECIFIED (1993) A PLEIOTROPIC REDUCED VIRULENCE (RVI-) MUTANT OF ERWINIA-CAROTOVORA SUBSPECIES ATROSEPTICA IS DEFECTIVE IN FLAGELLA ASSEMBLY PROTEINS THAT ARE CONSERVED IN PLANT AND ANIMAL BACTERIAL PATHOGENS. MOLECULAR MICROBIOLOGY, 9 (2). pp. 343-356. ISSN 0950-382X.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Abstract
Erwinia carotovora subsp. atroseptica was mutagenized and assayed for virulence in planta. Those mutants which exhibited reduced virulence (Rvi-) were assayed for growth rate, auxotrophy and extracellular enzyme secretion and seven mutants were found to be wild type for all of these phenotypes. When screened for other phenotypes, two were found to be non-motile. One mutant was complemented for motility by a heterologous gene library. A 2.7 kb XmaIII-ClaI complementing fragment was sequenced and the gene products were found to have similarity to flagella biosynthesis gene products from several bacteria. Further similarity was found to a pathogenicity protein from the plant pathogen Xanthomonas campestris pv. glycines and to the Spa pathogenicity proteins of the human pathogen Shigella flexneri, which are involved in the surface presentation of antigens. These studies highlight the emergence of common themes in the molecular strategies employed by both plant and animal bacterial pathogens for the targeting of proteins involved in the elaboration of disease.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QD Chemistry Q Science > QR Microbiology |
||||
Journal or Publication Title: | MOLECULAR MICROBIOLOGY | ||||
Publisher: | BLACKWELL SCIENCE LTD | ||||
ISSN: | 0950-382X | ||||
Official Date: | July 1993 | ||||
Dates: |
|
||||
Volume: | 9 | ||||
Number: | 2 | ||||
Number of Pages: | 14 | ||||
Page Range: | pp. 343-356 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |