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MALE ANTIFERTILITY COMPOUNDS FROM TRIPTERYGIUM-WILFORDII HOOK,F.
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UNSPECIFIED (1993) MALE ANTIFERTILITY COMPOUNDS FROM TRIPTERYGIUM-WILFORDII HOOK,F. CONTRACEPTION, 47 (4). pp. 387-400. ISSN 0010-7824.
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Abstract
Extracts of the Chinese medicinal plant, Tripterygium wilfordii, cause reversible infertility in male animals. Sub-fractionation studies have now revealed that the plant extracts contain a number of compounds which are potent antifertility agents in male mammals, including the diterpenes triptolide and tripdiolide and an isomer of the latter. A triptolide, 12,13- chlorohydrin, which is a transformation product formed reversibly by interaction of triptolide with HCl, was also found to be active.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > RG Gynecology and obstetrics | ||||
Journal or Publication Title: | CONTRACEPTION | ||||
Publisher: | BUTTERWORTH-HEINEMANN | ||||
ISSN: | 0010-7824 | ||||
Official Date: | April 1993 | ||||
Dates: |
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Volume: | 47 | ||||
Number: | 4 | ||||
Number of Pages: | 14 | ||||
Page Range: | pp. 387-400 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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