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Association between hypermutator phenotype, clinical variables, mucoid phenotype, and antimicrobial resistance in Pseudomonas aeruginosa
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Waine, David J., Honeybourne, David, Smith, E. Grace, Whitehouse, Joanna L. and Dowson, Christopher G. (2008) Association between hypermutator phenotype, clinical variables, mucoid phenotype, and antimicrobial resistance in Pseudomonas aeruginosa. Journal of Clinical Microbiology, Vol.46 (No.10). pp. 3491-3493. doi:10.1128/JCM.00357-08 ISSN 0095-1137.
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Official URL: http://dx.doi.org/10.1128/JCM.00357-08
Abstract
The presence of hypermutator Pseudomonas aeruginosa was associated with poorer lung function in patients at the Adult West Midlands CF Unit. Mucoid isolates were more likely to be hypermutators. The presence of resistant mutant subpopulations was associated with hypermutator phenotype but was not good enough to be used as a test for this phenotype.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QR Microbiology R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) > Biological Sciences ( -2010) Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) |
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Library of Congress Subject Headings (LCSH): | Pseudomonas aeruginosa, Drug resistance in microorganisms, Mucoids, Phenotype, Cystic fibrosis -- Pathophysiology | ||||
Journal or Publication Title: | Journal of Clinical Microbiology | ||||
Publisher: | American Society of Microbiology | ||||
ISSN: | 0095-1137 | ||||
Official Date: | October 2008 | ||||
Dates: |
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Volume: | Vol.46 | ||||
Number: | No.10 | ||||
Number of Pages: | 3 | ||||
Page Range: | pp. 3491-3493 | ||||
DOI: | 10.1128/JCM.00357-08 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | Heart of England NHS Foundation Trust (HENHSFT), Birmingham Heartlands Cystic Fibrosis Appeal Charity |
Data sourced from Thomson Reuters' Web of Knowledge
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