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Open-label comparative clinical study of chlorproguanil−dapsone fixed dose combination (Lapdap™) alone or with three different doses of artesunate for uncomplicated plasmodium falciparum malaria
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Wootton, Daniel G., Opara, Hyginus, Biagini, Giancarlo A., Kanjala, Maxwell K., Duparc, Stephan, Kirby, Paula L., Woessner, Mary, Neate, Colin, Nyirenda, Maggie, Blencowe, Hannah, Dube-Mbeye, Queen, Kanyok, Thomas, Ward, Stephen, Molyneux, Malcolm E., Dunyo, Sam and Winstanley, Peter (2008) Open-label comparative clinical study of chlorproguanil−dapsone fixed dose combination (Lapdap™) alone or with three different doses of artesunate for uncomplicated plasmodium falciparum malaria. PLoS One, Vol.3 (No.3). e1779. doi:10.1371/journal.pone.0001779 ISSN 1932-6203.
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Official URL: http://dx.doi.org/10.1371/journal.pone.0001779
Abstract
The objective of this study was to determine the appropriate dose of artesunate for use in a fixed dose combination therapy with chlorproguanil−dapsone (CPG−DDS) for the treatment of uncomplicated falciparum malaria.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > RM Therapeutics. Pharmacology | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
Library of Congress Subject Headings (LCSH): | Plasmodium falciparum -- Treatment, Artemisinin, Drugs -- Dose-response relationship | ||||
Journal or Publication Title: | PLoS One | ||||
Publisher: | Public Library of Science | ||||
ISSN: | 1932-6203 | ||||
Official Date: | 5 March 2008 | ||||
Dates: |
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Volume: | Vol.3 | ||||
Number: | No.3 | ||||
Page Range: | e1779 | ||||
DOI: | 10.1371/journal.pone.0001779 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Open Access (Creative Commons) | ||||
Date of first compliant deposit: | 17 December 2015 | ||||
Date of first compliant Open Access: | 17 December 2015 | ||||
Funder: | UNICEF, United Nations (UN), World Bank, World Health Organization (WHO), GlaxoSmithKline, Great Britain. Dept. for International Development |
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