The Library
Economic evaluation using decision analytical modelling : design, conduct, analysis, and reporting
Tools
Petrou, Stavros and Gray, Alastair (2011) Economic evaluation using decision analytical modelling : design, conduct, analysis, and reporting. BMJ, Vol.342 . d1766. doi:10.1136/bmj.d1766 ISSN 0959-8138.
|
PDF
WRAP_Petrou_bmj.d1766.full.pdf - Published Version - Requires a PDF viewer. Download (331Kb) |
Official URL: http://dx.doi.org/10.1136/bmj.d1766
Abstract
Economic evaluations are increasingly conducted alongside randomised controlled trials, providing researchers with individual patient data to estimate cost effectiveness. However, randomised trials do not always provide a sufficient basis for economic evaluations used to inform regulatory and reimbursement decisions. For example, a single trial might not compare all the available options, provide evidence on all relevant inputs, or be conducted over a long enough time to capture differences in economic outcomes (or even measure those outcomes). In addition, reliance on a single trial may mean ignoring evidence from other trials, meta-analyses, and observational studies. Under these circumstances, decision analytical modelling provides an alternative framework for economic evaluation.
Decision analytical modelling compares the expected costs and consequences of decision options by synthesising information from multiple sources and applying mathematical techniques, usually with computer software. The aim is to provide decision makers with the best available evidence to reach a decision—for example, should a new drug be adopted? Following on from our article on trial based economic evaluations, we outline issues relating to the design, conduct, analysis, and reporting
of economic evaluations using decision analytical modelling.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QA Mathematics > QA76 Electronic computers. Computer science. Computer software R Medicine > RA Public aspects of medicine |
||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||
Library of Congress Subject Headings (LCSH): | Medical economics, Clinical trials, Medical care, Cost of -- Research, Research -- Methodology, Information modeling, Decision trees | ||||
Journal or Publication Title: | BMJ | ||||
Publisher: | BMJ Group | ||||
ISSN: | 0959-8138 | ||||
Official Date: | 11 April 2011 | ||||
Dates: |
|
||||
Volume: | Vol.342 | ||||
Page Range: | d1766 | ||||
DOI: | 10.1136/bmj.d1766 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Date of first compliant deposit: | 17 December 2015 | ||||
Date of first compliant Open Access: | 17 December 2015 | ||||
Funder: | Medical Research Council (Great Britain) (MRC) |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |
Downloads
Downloads per month over past year