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Are some strokes preventable? The potential role of transcranial doppler in transient ischaemic attacks of carotid origin
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Imray, C. (Chris) and Tiivas, Carl A. S. (2005) Are some strokes preventable? The potential role of transcranial doppler in transient ischaemic attacks of carotid origin. The Lancet Neurology, Vol.4 (No.9). pp. 580-586. doi:10.1016/S1474-4422(05)70169-1 ISSN 1474-4422.
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Official URL: http://dx.doi.org/10.1016/S1474-4422(05)70169-1
Abstract
Transient ischaemic attacks (TIA) are more than just ministrokes. The high frequency of early stroke following TIA has resulted in the recent publication of guidelines in the UK. The guidelines recommend that patients attend a neurovascular clinic within 7 days of the index event to expedite investigation and treatment and so reduce the risk of a subsequent (potentially more serious) neurological event. After a TIA or stroke caused by carotid-artery disease, there is an increase in cerebral microemboli detectable by transcranial doppler (TCD). High microembolic loads appear to be surrogate markers for future neurological events, and the pharmacological efficacy of therapeutic interventions can now be rapidly and non-invasively assessed in the clinic or at the bedside. Medical treatments can now be optimised, avoiding the need for urgent or emergency carotid surgery and therefore allowing patients to undergo safer elective surgery when appropriate.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | The Lancet Neurology | ||||
Publisher: | The Lancet Publishing Group | ||||
ISSN: | 1474-4422 | ||||
Official Date: | 2005 | ||||
Dates: |
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Volume: | Vol.4 | ||||
Number: | No.9 | ||||
Page Range: | pp. 580-586 | ||||
DOI: | 10.1016/S1474-4422(05)70169-1 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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