2018

Chandrapalan, Subashini, Tahir, Faraz, Kimani, Peter K., Sinha, Rakesh and Arasaradnam, Ramesh P. (2018) Systematic review and meta-analysis : does colonic mural thickening on CT correlate with endoscopic findings at colonoscopy? Frontline Gastroenterology . doi:10.1136/flgastro-2018-100966 (In Press)

Arasaradnam, Ramesh P., Wicaksono, Alfian, O’Brien, Harrison, Kocher, Hemant M., Covington, James A. and Crnogorac-Jurcevic, Tatjana (2018) Non-invasive diagnosis of pancreatic cancer through detection of volatile organic compounds in urine. Gastroenterology, 154 (3). 485-487.e1. doi:10.1053/j.gastro.2017.09.054

2017

Patel, Abhilasha, Williams, Nigel, Parsons, Nicholas R., Ali, Omar, Peters, Francesca, Ranat, Reesha, Shah, Jasmine, Spector, Emma and Arasaradnam, Ramesh P. (2017) Risk factors for metachronous adenoma in the residual colon of patients undergoing curative surgery for colorectal cancer. International Journal of Colorectal Disease, 32 (11). pp. 1609-1616. doi:10.1007/s00384-017-2881-x

Freeman, Karoline, Taylor-Phillips, Sian, Connock, M., Court, Rachel A., Tsertsvadze, Alexander, Shyangdan, D. (Deepson), Auguste, Peter, Mistry, Hema, Arasaradnam, Ramesh P., Sutcliffe, P. (Paul) and Clarke, Aileen (2017) Test accuracy of drug and antibody assays for predicting response to anti-Tumour Necrosis Factor treatment in Crohn’s disease : a systematic review and meta-analysis. BMJ Open, 7 . e014581.

Bannaga, Ayman, Kelman, Lawrence, O'Connor, Michelle, Pitchford, Claire, Walters, Julian R F and Arasaradnam, Ramesh P. (2017) How bad is bile acid diarrhoea : an online survey of patient-reported symptoms and outcomes. BMJ Open Gastroenterology, 4 (1). e000116. doi:10.1136/bmjgast-2016-000116

2016

Arasaradnam, Ramesh P., McFarlane, Michael J., Daulton, Emma, Skinner, Jim, O’Connell, Nicola, Wurie, Subiatu, Chambers, Samantha, Nwokolo, Chuka U., Bardhan, Karna Dev, Savage, Richard S. and Covington, James A. (2016) Non-invasive exhaled volatile organic biomarker analysis to detect inflammatory bowel disease (IBD). Digestive and Liver Disease, 48 (2). pp. 148-153. pii/S1590865815301067. doi:10.1016/j.dld.2015.10.013

Freeman, Karoline, Connock, M., Auguste, Peter, Taylor-Phillips, Sian, Mistry, Hema, Shyangdan, D. (Deepson), Court, Rachel A., Arasaradnam, Ramesh P., Sutcliffe, P. (Paul) and Clarke, Aileen (2016) Clinical effectiveness and cost-effectiveness of use of therapeutic monitoring of tumour necrosis factor alpha (TNF-α) inhibitors [LISA-TRACKER® enzyme-linked immunosorbent assay (ELISA) kits, TNF-α-Blocker ELISA kits and Promonitor® ELISA kits] versus standard care in patients with Crohn’s disease: systematic reviews and economic modelling. Health Technology Assessment, 20 (83). pp. 1-288. doi:10.3310/hta20830

Mozdiak, Ella, Tsertsvadze, Alexander, McFarlane, Michael, Widlak, Monika, Tabuso, Maria, Dunlop, Amber and Arasaradnam, Ramesh P. (2016) The effect of the 2-week wait referral system on the detection of and mortality from colorectal cancer : protocol of a systematic review and meta-analysis. Systematic Reviews, 5 (1). 182. doi:10.1186/s13643-016-0358-6

Sagar, Nidhi M., Kay, Gemma L., O’Connell, N., Nwokolo, C., Bardhan, Karna Dev, Quince, Christopher, Pallen, Mark J. and Arasaradnam, Ramesh P. (2016) PWE-061 Dysbiosis in patients with bile acid diarrhoea (BAD) demonstrated using 16S RNA gene sequencing. In: British Society of Gastroenterology, Annual General Meeting, 20–23 Jun 2016. Published in: Gut, 65 (Supplement 1). A168-A168. ISSN 0017-5749. doi:10.1136/gutjnl-2016-312388.307

Sahota, Amandip S., Gowda, Ravi, Arasaradnam, Ramesh P., Daulton, Emma, Savage, Richard S., Skinner, Jim R., Adams, Emily, Ward, Stephen A. and Covington, James A. (2016) A simple breath test for tuberculosis using ion mobility : a pilot study. Tuberculosis, 99 . pp. 143-146. doi:10.1016/j.tube.2016.05.005

McFarlane, Michael, Chambers, Samantha, Malik, Ahmad, Lee, Bee, Sung, Edmond, Nwokolo, Chuka U., Waugh, Norman and Arasaradnam, Ramesh P. (2016) Clinical outcomes at 12 months and risk of inflammatory bowel disease in patients with an intermediate raised fecal calprotectin : a ‘real-world’ view. BMJ Open, 6 (6). pp. 1-6. e011041. doi:10.1136/bmjopen-2016-011041

Sahota, Amandip S., Gowda, Ravi, Arasaradnam, Ramesh P., Daulton, Emma, Savage, Richard S., Skinner, Jim R., Adams, Emily, Ward, Stephen A. and Covington, James A. (2016) Data for A simple breath test for Tuberculosis using ion mobility: A pilot study. [Dataset]

Mozdiak, E., Akhtar, J., Gowda, R. and Arasaradnam, Ramesh P. (2016) Familial mediterranean fever—anticipated rise in Western Europe. QJM . hcw059. doi:10.1093/qjmed/hcw059 (In Press)

Arasaradnam, Ramesh P., McFarlane, M., Ling, K., Wurie, S., O’Connell, N., Nwokolo, Chuka U., Bardhan, Karna Dev, Skinner, J., Savage, Richard S. and Covington, James A. (2016) Breathomics—exhaled volatile organic compound analysis to detect hepatic encephalopathy : a pilot study. Journal of Breath Research, 10 (1). pp. 1-6. 016012. doi:10.1088/1752-7155/10/1/016012

Esfahani, Siavash, Sagar, Nidhi M., Kyrou, Ioannis, Mozdiak, Ella, O’Connell, Nicola, Nwokolo, Chuka U., Bardhan, Karna Dev, Arasaradnam, Ramesh P. and Covington, James A. (2016) Variation in gas and volatile compound emissions from human urine as it ages, measured by an electronic nose. Biosensors, 6 (1). 4. doi:10.3390/bios6010004

Westenbrink, Eric W., O’Connell, Neil, Bailey, C., Nwokolo, Chuka U., Bardhan, Karna Dev, Arasaradnam, Ramesh P. and Covington, James A. (2016) PWE-116 Detection of colorectal cancer from urinary volatile organic compounds using a new chromatograph/electronic-nose instrument – Wolf System. In: British Society of Gastroenterology, Annual General Meeting, Liverpool , 20–23 Jun 2016. Published in: Gut, 65 (Supplement 1). A195.2-A196. ISSN 0017-5749. doi:10.1136/gutjnl-2016-312388.361

2015

Covington, James A., van. der Schee, M. P., Edge, A. S. L., Boyle, B., Savage, R. S. and Arasaradnam, Ramesh P. (2015) The application of FAIMS gas analysis in medical diagnostics. The Analyst, 140 (20). pp. 6775-6781. doi:10.1039/c5an00868a

Covington, James A., Mcfarlane, M., Kho, L., Wurie, S., O'Connell, N., Savage, R. S., Nwokolo, C., Bardhan, Karna Dev and Arasaradnam, Ramesh P. (2015) PWE-110 Breathomics – distinguishing minimal from overt hepatic encephalopathy using volatile organic compound analysis : a pilot study. Gut, 64 (Supplement 1). A260.2-A261. doi:10.1136/gutjnl-2015-309861.559

Covington, James A., Mcfarlane, M., Daulton, E., Westenbrink, E., O'Connell, N., Wurie, S., Nwokolo, C., Bardhan, Karna Dev, Savage, R. and Arasaradnam, Ramesh P. (2015) PWE-136 The non-invasive detection of non-alcoholic fatty liver disease using urinary volatile organic compound analysis : a pilot study. Gut, 64 (Supplement 1). A272.2-A272. doi:10.1136/gutjnl-2015-309861.584

Arasaradnam, Ramesh P., McFarlane, Michael J., Daulton, E., Westenbrink, Eric W., O'Connell, Nicola, Wurie, Subiatu, Nwokolo, Chuka U., Bardhan, Karna Dev, Savage, Richard S. and Covington, James A. (2015) Non-invasive distinction of non-alcoholic fatty liver disease using urinary volatile organic compound analysis : early results. Journal of Gastrointestinal and Liver Diseases, Volume 24 (Number 2). pp. 197-201. Article number 15. doi:10.15403/jgld.2014.1121.242.ury

Westenbrink, Eric W., Arasaradnam, Ramesh P., O'Connell, Nicola, Bailey, C., Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2015) Development and application of a new electronic nose instrument for the detection of colorectal cancer. Biosensors and Bioelectronics, Volume 67 . doi:10.1016/j.bios.2014.10.044

Arasaradnam, Ramesh P., Kho, Ling, McFarlane, Michael, Wurie, Subiatu, O'Connell, Nicola, Savage, Richard S., Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2015) Mo1019 : Breathomics - distinguishing minimal from overt hepatic encephalopathy by volatile organic compound detection in breath : a pilot study. Gastroenterology, 148 (4). S-1064. doi:10.1016/S0016-5085(15)33638-6

Sagar, Nidhi M., Cree, Ian A., Covington, James A. and Arasaradnam, Ramesh P. (2015) The interplay of the gut microbiome, bile acids, and volatile organic compounds. Gastroenterology Research and Practice, Volume 2015 . pp. 1-6. Article number 398585. doi:10.1155/2015/398585

Esfahani, Siavash , Skinner, J. R., Savage, Richard S., O'Connell, N., Kyrou, I., Nwokolo, C. U., Bardhan, Karna Dev, Arasaradnam, Ramesh P. and Covington, James A. (2015) A rapid discrimination of diabetic patients from volunteers using urinary volatile and an electronic nose. In: 16th International Symposium on Olfaction and Electronic Nose, Dijon, France, 28 Jun - 1 Jul 2015 (Unpublished)

2014

Arasaradnam, Ramesh P., Westenbrink, Eric W., McFarlane, Michael J., Harbord, Ruth, Chambers, Samantha, O’Connell, Nicola, Bailey, Catherine, Nwokolo, Chuka U., Bardhan, Karna Dev, Savage, Richard S. and Covington, James A. (2014) Differentiating coeliac disease from irritable bowel syndrome by urinary volatile organic compound analysis : a pilot study. PLoS One, 9 (10). e107312. doi:10.1371/journal.pone.0107312

Arasaradnam, Ramesh P., McFarlane, Michael J., Ryan-Fisher, Courtenay, Westenbrink, Eric W., Hodges, Paula, Thomas, Matthew G., Chambers, Samantha, O'Connell, Nicola, Bailey, Catherine, Harmston, Christopher, Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2014) Detection of Colorectal Cancer (CRC) by urinary volatile organic compound analysis. PLoS One, Volume 9 (Number 9). Article number e108750. doi:10.1371/journal.pone.0108750

Arasaradnam, Ramesh P., Covington, James A., Harmston, Christopher and Nwokolo, Chuka U. (2014) Review article : next generation diagnostic modalities in gastroenterology : gas phase volatile compound biomarker detection. Alimentary Pharmacology & Therapeutics, Volume 39 (Number 8). pp. 780-789. doi:10.1111/apt.12657

Dhaliwal, A., Zeino, Z., Tomkins, C., Cheung, M., Nwokolo, Chuka U., Smith, S., Harmston, Christopher and Arasaradnam, Ramesh P. (2014) Utility of faecal calprotectin in inflammatory bowel disease (IBD) : what cut-offs should we apply? Frontline Gastroenterology, Volume 6 (Number 1). pp. 14-19. doi:10.1136/flgastro-2013-100420

2013

Waugh, Norman, Cummins, E. (Ewen), Royle, Pamela, Kandala, Ngianga-Bakwin, Shyangdan, D. (Deepson), Arasaradnam, Ramesh P., Clar, C. and Johnston, R. (2013) Faecal calprotectin testing for differentiating amongst inflammatory and non-inflammatory bowel diseases : systematic review and economic evaluation. Health Technology Assessment, Volume 17 (Number 55). pp. 1-211. doi:10.3310/hta17550

Harrison, Elizabeth, Liu, Kuo-Kang, Petchey, Michael, Nwokolo, Chuka U., Loft, Duncan and Arasaradnam, Ramesh P. (2013) Selective measurement of anti-tTG antibodies in coeliac disease and IgA deficiency : an alternative pathway. Postgraduate Medical Journal, Volume 89 (Number 1047). pp. 4-7. doi:10.1136/postgradmedj-2011-130188

Arasaradnam, Ramesh P., Ouaret, N., Quraishi, N., Thomas, M. G., Heatherington, E., Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2013) A novel tool for noninvasive diagnosis and tracking of patients with inflammatory bowel disease. Inflammatory Bowel Diseases, Volume 19 (Number 5). pp. 999-1003. doi:10.1097/MIB.0b013e3182802b26

Covington, James A., Westenbrink, Eric W., Ouaret, Nathalie, Harbord, Ruth, Bailey, Catherine, O'Connell, Nicola, Cullis, James, Williams, Nigel, Nwokolo, Chuka U., Bardhan, Karna Dev and Arasaradnam, Ramesh P. (2013) Application of a novel tool for diagnosing bile acid diarrhoea. Sensors, Volume 13 (Number 9). pp. 11899-11912. doi:10.3390/s130911899

2012

Sung, E. Z. H., Arasaradnam, Ramesh P., Jarvie, E. M., James, Sean G., Goodyear, S. J., Borman, R. A., Snead, David R. J., Sanger, G. J. and Nwokolo, Chuka U. (2012) Effects of neo-adjuvant chemotherapy for oesophago-gastric cancer on neuro-muscular gastric function. Molecular Biology Reports, Vol.39 (No.12). pp. 9989-9994. doi:10.1007/s11033-012-1866-7

Arasaradnam, Ramesh P., Cullis, J., Nwokolo, Chuka U., Bardham, K. and Williams, N. (2012) Bile acid malabsorption and SeHCAT : the 'Cinderella' will be going to the Nuclear Medicine Ball! Nuclear Medicine Communications , Vol.33 (No.5). pp. 449-451. doi:10.1097/MNM.0b013e328351d516

Gardner, J. W., McIntosh, James, Ouaret, Natalie, Gold, Peter, Nwokolo, Chuka U., Bardhan, Karna Dev, Arasaradnam, Ramesh P. and Covington, James A. (2012) Classification of field asymmetric ion mobility spectrometry data for detection of bowel bacteria. In: 9th IASTED International Conference on Biomedical Engineering, BioMed 2012, Innsbruck; Austria, 15-17 Feb 2012. Published in: Proceedings of the 9th IASTED International Conference on Biomedical Engineering, BioMed 2012 pp. 309-314. ISBN 9780889869097. doi:10.2316/P.2012.764-032

Arasaradnam, Ramesh P. and Nwokolo, Chuka U. (2012) Epiphenomenon of telomere lengths : lessons from ulcerative colitis. Gut, Vol.61 (No.10). p. 1516. doi:10.1136/gutjnl-2012-302102

Arasaradnam, Ramesh P., Ouaret, N., Thomas, M. G., Gold, P., Quraishi, M. N., Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2012) Evaluation of gut bacterial populations using an electronic e-nose and field asymmetric ion mobility spectrometry: further insights into ‘fermentonomics’. Journal of Medical Engineering & Technology, Vol. 36 (No. 7). pp. 333-337. doi:10.3109/03091902.2012.690015

Arasaradnam, Ramesh P., Quraishi, M. N., Commane, Daniel M., Mathers, John C. and Bradburn, Mike (2012) MYOD-1 in normal colonic mucosa : role as a putative biomarker? BMC Research Notes, Vol.5 (No.1). p. 240. doi:10.1186/1756-0500-5-240

Arasaradnam, Ramesh P., Ouaret, N., Thomas, M. G., Hetherington, E., Quraishi, M. N., Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2012) OC-163 identification of inflammatory bowel disease (IBD) using field asymmetric ion mobility spectrometry (FAIMS). Gut, Vol.61 (Suppl.2). A70. doi:10.1136/gutjnl-2012-302514a.163

Covington, James A., Wedlake, L., Andreyev, J., Ouaret, N., Thomas, Matthew G., Nwokolo, Chuka U., Bardhan, Karna Dev and Arasaradnam, Ramesh P. (2012) The detection of patients at risk of gastrointestinal toxicity during pelvic radiotherapy by electronic nose and FAIMS : a pilot study. Sensors, Vol.12 (No.10). pp. 13002-13018. doi:10.3390/s121013002

2011

Arasaradnam, Ramesh P., Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2011) Electronic nose versus canine nose : clash of the titans. Gut, Vol.60 (No.12). p. 1768. doi:10.1136/gut.2011.241216

Sung, E. Z. H., Silva, N. F., Goodyear, S. J., McTernan, P. G. (Philip G.), Arasaradnam, Ramesh P. and Nwokolo, Chuka U. (2011) Ghrelin promotes nuclear factor kappa-B activation in a human B-lymphocyte cell line. Molecular Biology Reports, Vol.38 (No.8). pp. 4833-4838. doi:10.1007/s11033-010-0617-x

Arasaradnam, Ramesh P., Ouaret, N., Joseph, M., Nwokolo, Chuka U., Wedlake, L., Andreyev, J., Bardhan, Karna Dev and Covington, James A. (2011) Radiation-induced gut damage : identifying 'at risk' patients with an 'electronic nose' (E-NOSE). In: Digestive Disease Week (DDW) 2011, Chicago, U.S.A., May 7-10, 2011. Published in: Gastroenterology, Vol.140 (No.5 Suppl.1). S184-S185. ISSN 0016-5085. doi:10.1136/gut.2011.239301.227

Arasaradnam, Ramesh P., Ouaret, N., Joseph, M., Nwokolo, Chuka U., Wedlake, L., Andreyev, J., Bardhan, Karna Dev and Covington, James A. (2011) Radiation-induced gut damage : identifying 'at risk' patients with an 'electronic nose' (E-NOSE). In: Annual Meeting of British Society of Gasenterology, Birmingham, England, 14-17 Mar 2011. Published in: Gut, Vol.60 (Supp.1). A108-A109. ISSN 0017-5749. doi:10.1136/gut.2011.239301.227

Arasaradnam, Ramesh P., Quraishi, N., Kyrou, I., Nwokolo, Chuka U., Joseph, M., Kumar, Sudhesh, Bardhan, Karna Dev and Covington, James A. (2011) Insights into ‘fermentonomics’ : evaluation of volatile organic compounds (VOCs) in human disease using an electronic ‘e-nose’. Journal of Medical Engineering & Technology, Vol.35 (No.2). pp. 87-91. doi:10.3109/03091902.2010.539770

Covington, James A., Ouaret, N., Gardner, J. W., Nwokolo, Chuka U., Bardhan, Karna Dev and Arasaradnam, Ramesh P. (2011) Detection and identification of inflammatory bowel disease by electronic nose. In: 14th International Symposium on Olfaction and Electronic Nose (ISOEN 2011), New York City, U.S.A., May 2-5, 2011. Published in: Proceedings of the 14th International Symposium on Olfaction and Electronic Nose, Vol.1362 pp. 285-286. ISSN 0094-243X. doi:10.1063/1.3651653

2010

Arasaradnam, Ramesh P. (2010) The conundrum of folate and colorectal cancer (CRC) risk. European Journal of Clinical Nutrition, Vol.64 (No.12). p. 1501. doi:10.1038/ejcn.2010.183

Goodyear, S., Arasaradnam, Ramesh P., Quraishi, N., Mottershead, M. and Nwokolo, Chuka U. (2010) Acylated and des acyl ghrelin in human portal and systemic circulations. Molecular Biology Reports, Vol.37 (No.8). pp. 3697-3701. doi:10.1007/s11033-010-0022-5

Da-Silva, Nancy, Arasaradnam, Ramesh P., Getliffe, Katherine, Sung, E. Z. H., Oo, Ye and Nwokolo, Chuka U. (2010) Altered mRNA expression of telomere binding proteins (TPP1, POT1, RAP1, TRF1 and TRF2) in ulcerative colitis and Crohn's disease. Digestive and Liver Disease, Vol.42 (No.8). pp. 544-548. doi:10.1016/j.dld.2009.12.005

Arasaradnam, Ramesh P., Khoo, K. T. J., Bradburn, Mike, Mathers, John C. and Kelly, S. B. (2010) DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with Ulcerative Colitis (UC). Epigenetics, Vol.5 (No.5). pp. 422-426.

Arasaradnam, Ramesh P. and Nwokolo, Chuka U. (2010) Does premedication with hyoscine in routine colonoscopy affect caecal intubation rate and time? A randomized trial. In: Annual General Meeting of the British-Society-of-Gastroenterology, Liverpool, England, March 22-25, 2010. Published in: Gut, Vol.59 (No.Suppl. 1). A87-A87. ISSN 0017-5749. doi:10.1136/gut.2009.208942b

Arasaradnam, Ramesh P., Quraishi, N., Kumar, Sudhesh, Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2010) The gut in health and disease: scenting the difference by "electronic nose". In: Annual General Meeting of the British Society of Gastroenterology, Liverpool, England, March 22-25, 2010. Published in: Gut, Vol.59 (No.Suppl. 1). A42-A42. ISSN 0017-5749. doi:10.1136/gut.2009.208991x

Arasaradnam, Ramesh P., Quraishi, N., Kumar, Sudhesh, Nwokolo, Chuka U., Bardhan, Karna Dev and Covington, James A. (2010) The gut in health and disease: scenting the difference by "electronic nose". In: Digestive Disease Week 2010, New Orleans, LA, U.S.A., May 1-5, 2010 doi:10.1136/gut.2009.208991x

2009

Arasaradnam, Ramesh P., Pharaoh, Mark W., Williams, Geraint J., Nwokolo, Chuka U., Bardhan, Karna Dev and Kumar, Sudhesh (2009) Colonic fermentation – more than meets the nose. Medical Hypotheses, Vol.73 (No.5). pp. 753-756. doi:10.1016/j.mehy.2009.04.027

Commane, Daniel M., Arasaradnam, Ramesh P., Mills, Sarah, Mathers, John C. and Bradburn, Mike (2009) Diet, ageing and genetic factors in the pathogenesis of diverticular disease. World Journal of Gastroenterology, Vol.15 (No.20). pp. 2479-2488. doi:10.3748/wjg.15.2479

Arasaradnam, Ramesh P., Khoo, K. K. T., Commane, Daniel M., Kelly, S., Bradburn, Mike and Mathers, John C. (2009) Telomere attrition in non-dysplastic colorectal mucosa of patients with ulcerative colitis. In: Annual Meeting of the British-Society-of-Gastroenterology, Glasgow, Scotland, March 23-26, 2009. Published in: Gut, Vol.58 (Suppl. 1). A100-A100. ISSN 0017-5749.