Browse by Warwick Author

2024

Tomás, Ruben M. F., Dallmann, Robert, Congdon, Thomas R. and Gibson, Matthew I. (2024) Cryopreservation of assay-ready hepatocyte monolayers by chemically-induced ice nucleation : preservation of hepatic function and hepatotoxicity screening capabilities. Biomaterials Science, 11 (23). pp. 7639-7654. doi:10.1039/d3bm01046e ISSN 2047-4849.

Shi, Huayun, Ponte, Fortuna, Grewal, Jaspreet S., Clarkson, Guy J., Imberti, Cinzia, Hands-Portman, Ian, Dallmann, Robert, Sicilia, Emilia and Sadler, Peter J. (2024) Tuning the photoactivated anticancer activity of Pt( iv ) compounds via distant ferrocene conjugation. Chemical Science, 15 (11). pp. 4121-4134. doi:10.1039/d3sc03092j ISSN 2041-6520.

Vlachou, Denise, Veretennikova, Maria, Usselmann, Laura Emma Jane, Vasilyev, Vadim, Ott, Sascha, Bjarnason, Georg A., Dallmann, Robert, Lévi, Francis A. and Rand, David A. (2024) TimeTeller : a tool to probe the circadian clock as a multigene dynamical system. PLoS Computational Biology, 20 (2). e1011779. doi:10.1371/journal.pcbi.1011779 ISSN 1553-7358.

Marok, Fatima Zahra, Wojtyniak, Jan-Georg, Selzer, Dominik, Dallmann, Robert, Swen, Jesse J., Guchelaar, Henk-Jan, Schwab, Matthias and Lehr, Thorsten (2024) Personalized chronomodulated 5-fluorouracil treatment : a physiologically based pharmacokinetic precision dosing approach for optimizing cancer therapy. Clinical Pharmacology & Therapeutics . doi:10.1002/cpt.3181 ISSN 0009-9236. (In Press)

Vlachou, Denise, Veretennikova, Maria, Usselmann, Laura Emma Jane, Vasilyev, Vadim, Ott, Sascha, Bjarnason, Georg A., Dallmann, Robert, Lévi, Francis A. and Rand, David A. (2024) TimeTeller : a tool to probe the circadian clock as a multigene dynamical system. PLoS Computational Biology . ISSN 1553-7358. (In Press)

2023

Alcántara-Alonso, Viridiana, Dallmann, Robert, Lehnert, Hendrik, de Gortari, Patricia and Grammatopoulos, Dimitris K. (2023) CRH-R2 signalling modulates feeding and circadian gene expression in hypothalamic mHypoA-2/30 neurons. Frontiers in Endocrinology, 14 . 1266081. doi:10.3389/fendo.2023.1266081 ISSN 1664-2392.

Türk, Denise, Scherer, Nina, Selzer, Dominik, Dings, Christiane, Hanke, Nina, Dallmann, Robert, Schwab, Matthias, Timmins, Peter, Nock, Valerie and Lehr, Thorsten (2023) Significant impact of time-of-day variation on metformin pharmacokinetics. Diabetologia, 66 (6). pp. 1024-1034. doi:10.1007/s00125-023-05898-4 ISSN 0012-186X.

Wang, Jie, Dallmann, Robert, Lu, Renquan, Yan, Jing and Charmet, Jérôme (2023) Flow rate-independent multiscale liquid biopsy for precision oncology. ACS Sensors, 8 (3). pp. 1200-1210. doi:10.1021/acssensors.2c02577 ISSN 2379-3694.

Taylor, Lewis, Von Lendenfeld, Felix, Ashton, Anna, Sanghani, Harshmeena, Di Pretoro, Simona, Usselmann, Laura Emma Jane, Veretennikova, Maria, Dallmann, Robert, McKeating, Jane A., Vasudevan, Sridhar R. and Jagannath, Aarti (2023) Sleep and circadian rhythm disruption alters the lung transcriptome to predispose to viral infection. iScience, 26 (2). 105877. doi:10.1016/j.isci.2022.105877 ISSN 2589-0042.

2022

Chhetri, Jamuna, Dilek, Jem, Davies, Noel, Jacobson, Glenn, Dallmann, Robert and Gueven, Nuri (2022) NQO1 protects against clioquinol toxicity. Frontiers in Pharmacology, 13 . 1000278. doi:10.3389/fphar.2022.1000278 ISSN 1663-9812.

Gurnani, Pratik, Sanchez-Cano, Carlos, Xandri-Monje, Helena, Zhang, Junliang, Ellacott, Sean H., Mansfield, Edward D. H., Hartlieb, Matthias, Dallmann, Robert and Perrier, Sébastien (2022) Probing the effect of rigidity on the cellular uptake of core-shell nanoparticles : stiffness effects are size dependent. Small, 18 (38). 2203070. doi:10.1002/smll.202203070 ISSN 1613-6810.

Türk, Denise, Müller, Fabian, Fromm, Martin F., Selzer, Dominik, Dallmann, Robert and Lehr, Thorsten (2022) Renal transporter‐mediated drug‐biomarker interactions of the endogenous substrates creatinine and N 1 ‐methylnicotinamide : a PBPK modeling approach. Clinical Pharmacology & Therapeutics, 112 (3). pp. 687-698. doi:10.1002/cpt.2636 ISSN 0009-9236.

Smith, Ciearra B., van der Vinne, Vincent, McCartney, Eleanor, Stowie, Adam C., Leise, Tanya L., Blanca, Martin-Burgos, Molyneux, Penny C., Garbutt, Lauren A, Brodsky, Michael H., Davidson, Alec J., Harrington, Mary E., Dallmann, Robert and Weaver, David R. (2022) Cell-type specific circadian bioluminescence rhythms in Dbp reporter mice. Journal of Biological Rhythms, 37 (1). pp. 53-77. doi:10.11770748/7304211069452 ISSN 0748-7304.

2021

Innominato, Pasquale F., Komarzynski, Sandra, Dallmann, Robert, Wreglesworth, Nicholas, Bouchahda, Mohamed, Karaboué, Abdoulaye, Ulusakarya, Ayhan, Subbe, Christian, Spiegel, David and Lévi, Francis A. (2021) Impact of assessment frequency of patient-reported outcomes : an observational study using an eHealth platform in cancer patients. Supportive Care In Cancer, 29 . pp. 6167-6170. doi:10.1007/s00520-021-06262-1 ISSN 0941-4355.

Hancox, Thomas P. M., Skene, Debra J., Dallmann, Robert and Dunn, Warwick B. (2021) Tick-tock consider the clock : the influence of circadian and external cycles on time of day variation in the human metabolome - a review. Metabolites, 11 (5). 328. doi:10.3390/metabo11050328 ISSN 2218-1989.

(2021) Adenosine integrates light and sleep signalling for the regulation of circadian timing in mice. Nature Communications, 12 (1). 2113. doi:10.1038/s41467-021-22179-z ISSN 2041-1723.

Boltze, Johannes, Didwischus, Nadine, Merrow, Martha, Dallmann, Robert and Plesnila, N. (2021) Circadian effects on stroke outcome – did we not wake up in time for neuroprotection? Journal of Cerebral Blood Flow & Metabolism, 41 (3). pp. 684-686. doi:10.1177/0271678X20978711 ISSN 0271-678X.

Stephenson, Ewan Michael, Usselmann, Laura Emma Jane, Tergaonkar, Vinay, Virshup, David and Dallmann, Robert (2021) Cancer clocks in tumourigenesis : the p53 pathway and beyond. Endocrine-Related Cancer, 28 (4). R95-R110. doi:10.1530/ERC-20-0475 ISSN 1351-0088.

Kumar, Swati, Needham, Russell J., Abraham, Kristin, Bridgewater, Hannah E., Garbutt, Lauren A, Xandri-Monje, Helena, Dallmann, Robert, Perrier, Sébastien, Sadler, Peter J. and Lévi, Francis A. (2021) Dose and time-dependent tolerability and efficacy of organo-osmium complex FY26 and its tissue pharmacokinetics in hepatocarcinoma-bearing mice. Metallomics, 13 (2). mfaa003. doi:10.1093/mtomcs/mfaa003 ISSN 1756-5901.

2020

Yan, Chang, Luo, Zhuo, Li, Wen, Li, Xue, Dallmann, Robert, Kurihara, Hiroshi, Li, Yi-Fang and He, Rong-Rong (2020) Disturbed Yin-Yang balance : stress increases the susceptibility to herpes simplex virus type 1 primary and recurrent infections. Acta Pharmaceutica Sinica B, 10 (3). pp. 383-398. doi:10.1016/j.apsb.2019.06.005 ISSN 2211-3835.

Charmet, Jérôme, Rodrigues, Rui, Yildirim, Ender, Kumar Challa, Pavan, Roberts, Benjamin, Dallmann, Robert and Whulanza, Yudan (2020) Low-cost microfabrication tool box. Micromachines, 11 (2). 135. doi:10.3390/mi11020135 ISSN 2072-666X.

2019

Gurnani, Pratik, Sanchez-Cano, Carlos, Abraham, Kristin, Xandri-Monje, Helena, Cook, Alexander B., Hartlieb, Matthias, Lévi, Francis A., Dallmann, Robert and Perrier, Sébastien (2019) RAFT emulsion polymerization as a platform to generate well-defined biocompatible latex nanoparticles. Macromolecular Bioscience, 18 (10). 1800213. doi:10.1002/mabi.201800213 ISSN 1616-5187.

Okyar, Alper, Kumar, Swati, Filipski, Elisabeth, Piccolo, Enza, Ozturk, Narin, Xandri-Monje, Helena, Pala-Kara, Zeliha, Abraham, Kristin, Gato de Jesus Gomes, Ana Rita, Orman, Mehmet N., Li, Robert Xiao-Mei, Dallmann, Robert, Lévi, Francis A. and Ballesta, Annabelle (2019) Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling. Scientific Reports, 9 . 10505. doi:10.1038/s41598-019-46977-0 ISSN 2045-2322.

Cook, Alexander B., Peltier, Raoul, Zhang, Junliang, Gurnani, Pratik, Tanaka, Joji, Burns, James A., Dallmann, Robert, Hartlieb, Matthias and Perrier, Sébastien (2019) Hyperbranched poly(ethylenimine-co-oxazoline) by thiol–yne chemistry for non-viral gene delivery : investigating the role of polymer architecture. Polymer Chemistry, 10 (10). pp. 1202-1212. doi:10.1039/C8PY01648H ISSN 1759-9954.

2018

Innominato, Pasquale F., Komarzynski, Sandra, Palesh, Oxana G., Dallmann, Robert, Bjarnason, Georg A., Giacchetti , Syvie, Ulusakarya , Ayhan, Bouchahda, Mohamed, Haydar, Mazen, Ballesta, Annabelle, Karaboué, Abdoulaye, Wreglesworth, Nicholas I., Spiegel, David and Lévi, Francis A. (2018) Circadian rest-activity rhythm as an objective biomarker of patient-reported outcomes in patients with advanced cancer. Cancer Medicine, 7 (9). pp. 4396-4405. doi:10.1002/cam4.1711 ISSN 2045-7634.

Middleton, Bethany J., Couling, Kevin, Dallmann, Robert, Goodship, Vannessa and Charmet, Jérôme (2018) Low-cost injection moulding strategies for the fabrication of organ on a chip devices. In: BioMedEng18, London, 6-7 Sep 2018. Published in: BioMedEng18 p. 269. ISBN 9781999646509.

Schmitt, Karen, Grimm, Amandine, Dallmann, Robert, Oettinghaus, Bjoern, Restelli, Lisa Michelle, Witzig, Melissa, Ishihara, Naotada, Mihara, Katsuyoshi, Ripperger, Jürgen A., Albrecht, Urs, Frank, Stephan, Brown, Steven A. and Eckert, Anne (2018) Circadian control of DRP1 activity regulates mitochondrial dynamics and bioenergetics. Cell Metabolism, 27 (3). pp. 657-666. doi:10.1016/j.cmet.2018.01.011 ISSN 1550-4131.

Bergamini, Giorgio, Mechtersheimer, Jonas , Azzinnari, Damiano, Sigrist, Hannes, Buerge, Michaela, Dallmann, Robert, Freije, Robert, Kouraki, Alfroditi, Opacka-Juffry, Jolanta, Seifritz, Erich, Ferger, Boris, Suter, Tobias and Pryce, Christopher R. (2018) Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice. Neurobiology of Stress, 8 . pp. 42-56. doi:10.1016/j.ynstr.2018.01.004 ISSN 2352-2895.

Zhang, Yuan, Giacchetti, Sylvie, Parouchev, Alexandre, Hadadi, Eva, Li, Xiaomei, Dallmann, Robert, Xandri-Monje, Helena, Portier, Lucie, Adam, René, Lévi, Francis A., Dulong, Sandrine and Chang, Yunhua (2018) Dosing time dependent in vitro pharmacodynamics of Everolimus despite a defective circadian clock. Cell Cycle, 17 (1). pp. 33-42. doi:10.1080/15384101.2017.1387695 ISSN 1538-4101.

2017

Ballesta, Annabelle, Innominato, Pasquale F., Dallmann, Robert, Rand, D. A. (David A.) and Lévi, Francis A. (2017) Systems chronotherapeutics. Pharmacological Reviews, 69 (2). pp. 161-199. doi:10.1124/pr.116.013441 ISSN 0031-6997.

Martinez-Lozano Sinues, P., Kohler, M., Brown, S. A., Zenobi, R. and Dallmann, Robert (2017) Gauging circadian variation in ketamine metabolism by real-time breath analysis. Chemical Communications, 53 (14). pp. 2264-2267. doi:10.1039/C6CC09061C ISSN 1359-7345.

2016

Jansen, Heiko T. , Leise, Tanya, Stenhouse, Gordon, Pigeon, Karine, Kasworm, Wayne, Teisberg, Justin, Radandt, Thomas, Dallmann, Robert, Brown, Steven and Robbins, Charles T. (2016) The bear circadian clock doesn’t ‘sleep’ during winter dormancy. Frontiers in Zoology, 13 (42). doi:10.1186/s12983-016-0173-x ISSN 1742-9994 .

Dallmann, Robert, Okyar, Alper and Lévi, Francis A. (2016) Dosing-time makes the poison : circadian regulation and pharmacotherapy. Trends in Molecular Medicine, 22 (5). pp. 430-445. doi:10.1016/j.molmed.2016.03.004 ISSN 1471-4914.

2015

Li, Xue, Martinez-Lozano Sinues, Pablo, Dallmann, Robert, Bregy, Lukas, Hollmén, Maija, Proulx, Steven, Brown, Steven A., Detmar, Michael, Kohler, Malcolm and Zenobi, Renato (2015) Drug pharmacokinetics determined by real-time analysis of mouse breath. Angewandte Chemie International Edition, Volume 54 (Number 27). pp. 7815-7818. doi:10.1002/anie.201503312 ISSN 1433-7851.

2014

Martinez-Lozano Sinues, Pablo, Tarokh, Leila, Li, Xue, Kohler, Malcolm, Brown, Steven A., Zenobi, Renato and Dallmann, Robert (2014) Circadian variation of the human metabolome captured by real-time breath analysis. PLoS One, 9 (12). pp. 1-16. e114422. doi:10.1371/journal.pone.0114422 ISSN 1932-6203.

DeBruyne, Jason P., Weaver, D. R. and Dallmann, Robert (2014) The hepatic circadian clock modulates xenobiotic metabolism in mice. Journal of Biological Rhythms, 29 (4). pp. 277-287. doi:10.1177/0748730414544740 ISSN 0748-7304.

Azzi, Abdelhalim, Dallmann, Robert, Casserly, Alison, Rehrauer, Hubert, Patrignani, Andrea, Maier, Bert, Kramer, Achim and Brown, Steven A. (2014) Circadian behavior is light-reprogrammed by plastic DNA methylation. Nature Neuroscience, 17 (3). pp. 377-382. doi:10.1038/nn.3651 ISSN 1097-6256.

Dallmann, Robert, Brown, Steven A. and Gachon, F. (2014) Chronopharmacology : new insights and therapeutic implications. Annual Review of Pharmacology and Toxicology, 54 . pp. 339-361. doi:10.1146/annurev-pharmtox-011613-135923 ISSN 0362-1642.

DeBruyne, Jason P., Weaver, David R. and Dallmann, Robert (2014) The hepatic circadian clock modulates xenobiotic metabolism in mice. Journal of Biological Rhythms, 29 (4). pp. 277-87. doi:10.1177/0748730414544740 ISSN 0748-7304.

2012

Brown, Steven A., Kowalska, Elzbieta and Dallmann, Robert (2012) (Re)inventing the circadian feedback loop. Developmental Cell, 22 (3). pp. 477-87. doi:10.1016/j.devcel.2012.02.007 ISSN 1534-5807.

Dallmann, Robert, Viola, Antoine U., Tarokh, Leila, Cajochen, Christian and Brown, Steven A. (2012) The human circadian metabolome. Proceedings of the National Academy of Sciences of the United States of America, 109 (7). pp. 2625-2629. doi:10.1073/pnas.1114410109 ISSN 0027-8424.

2011

Dallmann, Robert, DeBruyne, Jason P. and Weaver, David R. (2011) Photic resetting and entrainment in CLOCK-deficient mice. Journal of Biological Rhythms, 26 (5). pp. 390-401. doi:10.1177/0748730411414345 ISSN 0748-7304.

(2011) The orally active melanocortin-4 receptor antagonist BL-6020/979 : a promising candidate for the treatment of cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle, 2 (3). pp. 163-174. doi:10.1007/s13539-011-0039-1 ISSN 2190-5991.

Haefeli, Roman H., Erb, Michael, Gemperli, Anja C., Robay, Dimitri, Fruh, Isabelle Courdier, Anklin, Corinne, Dallmann, Robert and Gueven, Nuri (2011) NQO1-dependent redox cycling of idebenone : effects on cellular redox potential and energy levels. PLoS One, 6 (3). pp. 1-12. e17963. doi:10.1371/journal.pone.0017963 ISSN 1932-6203.