2013

Pietroni, Paola, Vasisht, Nishi, Cook, Jonathan P., Roberts, David M., Lord, Mike, Hartmann-Petersen, Rasmus, Roberts, L. M. (Lynne M.) and Spooner, Robert A. (2013) The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain. Biochemical Journal, Volume 453 (Number 3). pp. 435-445. doi:10.1042/BJ20130133

2012

Lee, Hannah, Ph.D., Sparkes, Imogen, Gattolin, Stefano, Dzimitrowicz, Natasha, Roberts, L. M. (Lynne M.), Hawes, C. R. and Frigerio, Lorenzo (2012) An Arabidopsis reticulon and the atlastin homologue RHD3-like2 act together in shaping the tubular endoplasmic reticulum. New Phytologist, Volume 197 (Number 2). pp. 481-489. doi:10.1111/nph.12038

Li, Shuyu, Spooner, Robert A. , Hampton, Randolph Y., Lord, Mike and Roberts, L. M. (Lynne M.) (2012) Cytosolic entry of Shiga-like toxin A chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p. PLoS ONE, Vol.7 (No.7). e41119. doi:10.1371/journal.pone.0041119

2011

Sorieul, Mathias, Langhans, Markus, Guetzoyan, Lucie J., Hillmer, Stefan, Clarkson, Guy J., Lord, Mike, Roberts, L. M. (Lynne M.), Robinson, David G., Spooner, Robert A. and Frigerio, Lorenzo (2011) An Exo2 derivative affects ER and Golgi morphology and vacuolar sorting in a tissue-specific manner in arabidopsis. Traffic, Vol.12 (No.11). pp. 1552-1562. doi:10.1111/j.1600-0854.2011.01258.x

Pawar, Vidya, De, Antara, Briggs, Laura, Omar, Mahmoud M., Sweeney, Sean T., Lord, Mike, Roberts, L. M. (Lynne M.), Spooner, Robert A. and Moffat, Kevin G. (2011) RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Journal of Biomolecular Screening, Vol.16 (No.4). pp. 436-442. doi:10.1177/1087057110397890

2010

Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x

Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, Schnöder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743

Marshall, Richard S., Frigerio, Lorenzo and Roberts, L. M. (Lynne M.) (2010) Disulfide formation in plant storage vacuoles permits assembly of a multimeric lectin. Biochemical Journal, Vol.427 (No.Part 3). pp. 513-521. doi:10.1042/BJ20091878

Guetzoyan, Lucie J., Spooner, Robert A. , Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking. European Journal of Medicinal Chemistry, Vol.45 (No.1). pp. 275-283. doi:10.1016/j.ejmech.2009.10.007

Guetzoyan, Lucie J., Spooner, Robert A. , Boal, Frédéric, Stephens, David J., Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells. Molecular BioSystems, Vol.6 (No.10). pp. 2030-2038. doi:10.1039/c0mb00035c

Frigerio, Lorenzo and Roberts, L. M. (Lynne M.) (2010) The Synthesis of Ricinus communis Lectins. In: Toxic Plant Proteins. Plant Cell Monographs, Vol.18 . Berlin, Heidelberg: Springer, pp. 191-205. ISBN 978-3-6421-2175-3

2009

Marshall, Richard S., Jolliffe, Nicholas A., Ceriotti, Aldo, Snowden, Christopher J., Lord, Mike, Frigerio, Lorenzo and Roberts, L. M. (Lynne M.) (2009) The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells. Journal of Biological Chemistry, Vol.283 . pp. 15869-15877. doi:10.1074/jbc.M709316200

Mayerhofer, Peter U., Cook, Jonathan P., Wahlman, Judit, Pinheiro, Teresa J. T., Moore, Katherine A. H., Lord, Mike, Johnson, Arthur E. and Roberts, L. M. (Lynne M.) (2009) Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 degrees C. Journal of Biological Chemistry, Vol.284 (No.15). pp. 10232-10242. doi:10.1074/jbc.M808387200

2008

Chamberlain, Kerry L., Marshall, Richard S., Jolliffe, Nicholas A., Frigerio, Lorenzo, Ceriotti, Aldo, Lord, Mike and Roberts, L. M. (Lynne M.) (2008) Ricin B chain targeted to the endoplasmic reticulum of tobacco protoplasts is degraded by a CDC48- and vacuole-independent mechanism. Journal of Biological Chemistry, Vol.283 (No.48). pp. 33276-33286. doi:10.1074/jbc.M805222200

Spooner, Robert A., Harte, Philip J. , Cook, Jonathan P., Pietroni, Paola, Rogon, Christian, Höhfeld, Jörg, Roberts, L. M. (Lynne M.) and Lord, Mike (2008) Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.45). pp. 17408-17413. doi:10.1073/pnas.0809013105

Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, Frédéric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149

Castilho, Priscila V., Goto, Leandro S., Roberts, L. M. (Lynne M.) and Araujo, Ana Paula U. (2008) Isolation and characterization of four type 2 ribosome inactivating pulchellin isoforms from Abrus pulchellus seeds. FEBS Journal, Vol.275 (No.5). pp. 948-959. doi:10.1111/j.1742-4658.2008.06258.x

Tolley, Nicholas, Sparkes, Imogen, Hunter, P. R. (Paul R.), Craddock, Christian P., Nuttall, J. (James), Roberts, L. M. (Lynne M.), Hawes, C. R., Pedrazzini, Emanuela and Frigerio, Lorenzo (2008) Overexpression of a plant reticulon remodels the lumen of the cortical endoplasmic reticulum but does not perturb protein transport. Traffic, Vol.9 (No.1). pp. 94-102. doi:10.1111/j.1600-0854.2007.00670.x

2007

Hunter, Paul R., Craddock, Christian P., Di Benedetto, Sara, Roberts, L. M. (Lynne M.) and Frigerio, Lorenzo (2007) Fluorescent reporter proteins for the tonoplast and the vacuolar lumen identify a single vacuolar compartment in Arabidopsis cells. Plant Physiology, Vol.145 (No.4). pp. 1371-1382. doi:10.1104/pp.107.103945

Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterization of temperature-dependent ricin A chain molecules in Saccharomyces cerevisiae. FEBS JOURNAL, 274 (21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x

Allen, Stuart C. H., Moore, Katherine A. H., Marsden, Catherine J., Fülöp, Vilmos, Moffat, Kevin G., Lord, Mike, Ladds, Graham and Roberts, L. M. (Lynne M.) (2007) The isolation and characterisation of temperature-dependent Ricin A chain molecules in Saccharomyces cerevisiae. FEBS Journal, Vol.274 (No.21). pp. 5586-5599. doi:10.1111/j.1742-4658.2007.06080.x

Amessou, Mohamed, Fradagrada, Alexandre, Falguières, Thomas, Lord, Mike, Smith, Daniel C., Roberts, L. M. (Lynne M.), Lamaze, Christophe and Johannes, Ludger (2007) Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins. Journal of Cell Science, Vol.120 (No.8). pp. 1457-1468. doi:10.1242/jcs.03436

2006

Jolliffe, Nicholas A., Di Cola, Alessandra, Marsden, Catherine J., Lord, Mike, Ceriotti, Aldo, Frigerio, Lorenzo and Roberts, L. M. (Lynne M.) (2006) The N-terminal ricin propeptide influences the fate of ricin A-chain in tobacco protoplasts. JOURNAL OF BIOLOGICAL CHEMISTRY, 281 (33). pp. 23377-23385. doi:10.1074/jbc.M602678200

Williams, Jonathan P., Smith, Daniel C. , Green, Brian N., Marsden, Brian D., Jennings, Keith R., Roberts, L. M. (Lynne M.) and Scrivens, James H. (2006) Gas phase characterization of the noncovalent quaternary structure of Cholera toxin and the Cholera toxin B subunit pentamer. Biophysical Journal, Vol.90 (No.9). pp. 3246-3254. doi:10.1529/biophysj.105.076455

Spooner, Robert A. , Smith, Daniel C., Easton, A. J. (Andrew J.), Roberts, L. M. (Lynne M.) and Lord, Mike (2006) Retrograde transport pathways utilised by viruses and protein toxins. Virology Journal, Vol.3 . p. 26. doi:10.1186/1743-422X-3-26

Smith, Daniel C. , Sillence, Daniel J., Falguières, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035

2005

Smith, Daniel C., Spooner, Robert A. , Watson, P. D., Murray, J. L. , Hodge, T. W., Amessou, Mohamed, Johannes, Ludger, Lord, J.M. and Roberts, L. M. (Lynne M.) (2005) Internalized pseudomonas exotoxin A can exploit multiple pathways to reach the endoplasmic reticulum. Traffic, Volume 7 (Number 4). pp. 379-393. doi:10.4132/KoreanJPathol.2009.43.5.471

2004

Spooner, Robert A. , Watson, Peter, Marsden, Catherine J., Smith, Daniel C., Moore, Katherine A. H., Cook, Jonathan P., Lord, Mike and Roberts, L. M. (Lynne M.) (2004) Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum. Biochemical Journal, Vol.383 (No.2). pp. 285-293. doi:10.1042/BJ20040742