2016

Ude, Ziga, Romero-Canelón, Isolda, Twamley, Brendan, Fitzgerald Hughes, Deirdre, Sadler, P. J. and Marmion, Celine J.. (2016) A novel dual-functioning ruthenium(II)–arene complex of an anti-microbial ciprofloxacin derivative — anti-proliferative and anti-microbial activity. Journal of Inorganic Biochemistry, 160 . pp. 210-217. ISSN 0162-0134

Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J.. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition . pp. 1-5. ISSN 1433-7851 (In Press)

Fu, Ying, Sanchez-Cano, Carlos, Soni, Rina, Romero-Canelón, Isolda, Hearn, Jessica M., Liu, Zhe, Wills, Martin and Sadler, P. J.. (2016) The contrasting catalytic efficiency and cancer cell antiproliferative activity of stereoselective organoruthenium transfer hydrogenation catalysts. Dalton Transactions, 45 (20). pp. 8367-8378. ISSN 1477-9226

Venkatesh, V., Wedge, Christopher J., Romero-Canelón, Isolda, Habtemariam, Abraha and Sadler, P. J.. (2016) Spin-labelled photo-cytotoxic diazido platinum(iv) anticancer complex. Dalton Transactions, 45 . pp. 13034-13037. ISSN 1477-9226

Vernooij, Robbin, Joshi, Tanmaya, Shaili, Evyenia, Kubeil, Manja, Appadoo, Dominique R. T., Izgorodina, Ekaterina I., Graham, Bim, Sadler, P. J., Wood, Bayden R. and Spiccia, Leone (2016) Dataset to support: 'Comprehensive vibrational spectroscopic investigation of trans,trans,trans-[Pt(N3)2(OH)2(py)2], a Pt(IV) diazido anticancer prodrug candidate'. [Dataset]

Venkatesh, V., Wedge, Christopher, Romero-Canelón, Isolda, Habtemariam, Abraha and Sadler, P. J. (2016) Dataset supporting 'Spin-labelled photo-cytotoxic diazido platinum(IV) anticancer complex'. [Dataset]

Pitto-Barry, Anaïs, Sadler, P. J. and Barry, Nicolas P. E.. (2016) Dynamics of formation of Ru, Os, Ir and Au metal nanocrystals on doped graphitic surfaces. Chemical Communications, 52 (20). pp. 3895-3898. c5cc09564f. ISSN 1359-7345

Vernooij, Robbin, Joshi, Tanmaya, Shaili, Evyenia, Kubeil, Manja, Appadoo, Dominique R. T., Izgorodina, Ekaterina I., Graham, Bim, Sadler, P. J., Wood, Bayden R. and Spiccia, Leone. (2016) Comprehensive vibrational spectroscopic investigation of trans,trans,trans-[Pt(N3)2(OH)2(py)2], a Pt(IV) diazido anticancer prodrug candidate. Inorganic Chemistry, 55 (12). pp. 5983-5992. ISSN 0020-1669

Greenough, Simon E., Horbury, Michael D., Smith, Nicholas A., Sadler, P. J., Paterson, Martin J. and Stavros, Vasilios G.. (2016) Excited-state dynamics of a two-photon-activatable ruthenium prodrug. ChemPhysChem, 17 (2). pp. 221-224. ISSN 1439-4235

Smith, Nicholas A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G. and Sadler, P. J.. (2016) Combatting AMR : photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity. Chemical Science . ISSN 2041-6520 (In Press)

2015

Soldevila-Barreda, Joan J., Habtemariam, Abraha, Romero-Canelón, Isolda and Sadler, P, J.. (2015) Half-sandwich rhodium(III) transfer hydrogenation catalysts : reduction of NAD+ and pyruvate, and antiproliferative activity. Journal of Inorganic Biochemistry, 153 . pp. 322-333. ISSN 0162-0134

Romero-Canelón, Isolda, Phoenix, Ben, Pitto-Barry, Anaïs, Tran, Johanna, Soldevila-Barreda, Joan J., Kirby, Nigel, Green, Stuart, Sadler, P. J. and Barry, Nicolas P. E.. (2015) Arene ruthenium dithiolato–carborane complexes for boron neutron capture therapy (BNCT). Journal of organometallic chemistry, 796 . ISSN 0022-328X (In Press)

Pitto-Barry, Anaïs, Perdigao, Luis, Walker, Marc, Lawrence, James, Costantini, Giovanni, Sadler, P. J. and Barry, Nicolas P. E.. (2015) Synthesis and controlled growth of osmium nanoparticles by electron irradiation. Dalton Transactions, 44 (47). pp. 20308-20311. ISSN 1477-9226

Romero-Canelón, Isolda, Mos, Magdalena and Sadler, P. J.. (2015) Enhancement of selectivity of an organometallic anticancer agent by redox modulation. Journal of Medicinal Chemistry, 58 (19). pp. 7874-7880. ISSN 0022-2623

Zou, Taotao and Sadler, P. J.. (2015) Speciation of precious metal anti-cancer complexes by NMR spectroscopy. Drug Discovery Today : Technologies, 16 . pp. 7-15. ISSN 1740-6749

Barry, Nicolas P. E., Pitto-Barry, Anaïs, Tran, Johanna, Spencer, Simon E. F., Johansen, Adam M., Sanchez, Ana M., Dove, Andrew P., O’Reilly, Rachel K., Deeth, Robert J., Beanland, Richard and Sadler, P. J.. (2015) Osmium atoms and Os2 molecules move faster on selenium-doped compared to sulfur-doped boronic graphenic surfaces. Chemistry of Materials, 27 (14). pp. 5100-5105. ISSN 0897-4756

Millett, Adam J., Habtemariam, Abraha, Romero-Canelón, Isolda, Clarkson, Guy J. and Sadler, P. J.. (2015) Contrasting anticancer activity of half-sandwich iridium(III) complexes bearing functionally diverse 2-phenylpyridine ligands. Organometallics, Volume 34 (Number 11). pp. 2683-2694. ISSN 0276-7333

Coverdale, James P. C., Sanchez-Cano, Carlos, Clarkson, Guy J., Soni, Rina, Wills, Martin and Sadler, P. J.. (2015) Easy To synthesize, robust organo-osmium asymmetric transfer hydrogenation catalysts. Chemistry - A European Journal, 21 (22). pp. 8043-8046. ISSN 0947-6539

Soldevila-Barreda, Joan J., Romero-Canelón, Isolda, Habtemariam, Abraha and Sadler, P. J.. (2015) Transfer hydrogenation catalysis in cells as a new approach to anticancer drug design. Nature Communications, 6 . pp. 1-9. 6582. ISSN 2041-1723

Chellan , Prinessa and Sadler, P. J.. (2015) The elements of life and medicines. Philosophical Transactions of the Royal Society A : Mathematical, Physical and Engineering Sciences, Volume 373 (Number 2037). Article number 20140182. ISSN 1364-503X

Soldevila-Barreda, Joan J. and Sadler, P.J.. (2015) Approaches to the design of catalytic metallodrugs. Current Opinion in Chemical Biology, Volume 25 . pp. 172-183. ISSN 1367-5931

2014

Sousa, Eduardo Henrique Silva, de Mesquita Vieira, Francisca Gilmara, Butler, Jennifer S. (Jennifer Suzanne), Basso, Luiz Augusto, Santiago, Diógenes S., Diógenes, Izaura C.N., Lopes, Luiz Gonzaga de França and Sadler, P.J.. (2014) [Fe(CN)5(isoniazid)]3−: an iron isoniazid complex with redox behavior implicated in tuberculosis therapy. Journal of Inorganic Biochemistry, Volume 140 . pp. 236-244. ISSN 0162-0134

Barry, Nicolas P. E., Pitto-Barry, Anaïs, Romero-Canelón, Isolda, Tran, Johanna, Soldevila-Barreda, Joan J., Hands-Portman, Ian, Smith, Corinne J., Kirby, Nigel, Dove, Andrew P., O'Reilly, Rachel K. and Sadler, P.J. (2014) Precious metal carborane polymer nanoparticles : characterisation of micellar formulations and anticancer activity. Faraday Discussions, 175 . pp. 229-240. ISSN 0301-7249

Liu, Zhe (Researcher in chemistry), Romero-Canelón, Isolda, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J.. (2014) Potent half-sandwich iridium(III) anticancer complexes containing C∧N-Chelated and pyridine ligands. Organometallics, 33 (19). pp. 5324-5333. ISSN 0276-7333

Li, Huilin, Snelling, Jonathon R., Barrow, Mark P., Scrivens, James H., Sadler, P. J. and O’Connor, Peter B.. (2014) Mass spectrometric strategies to improve the identification of Pt(II)-modification sites on peptides and proteins. Journal of The American Society for Mass Spectrometry, 25 (7). pp. 1217-1227. ISSN 1044-0305

Barry, Nicolas P. E., Pitto-Barry, Anaïs, Sanchez, Ana M., Dove, Andrew P., Procter, Richard J., Soldevila-Barreda, Joan J., Kirby, Nigel, Hands-Portman, Ian, Smith, Corinne J., O'Reilly, Rachel K., Beanland, R. and Sadler, P. J.. (2014) Fabrication of crystals from single metal atoms. Nature Communications, Volume 5 . Article number 3851 . ISSN 2041-1723

Rijt, Sabine H. van, Romero-Canelón, Isolda, Fu, Ying, Shnyder, Steve D. and Sadler, P. J.. (2014) Potent organometallic osmium compounds induce mitochondria-mediated apoptosis and S-phase cell cycle arrest in A549 non-small cell lung cancer cells. Metallomics, 6 (5). pp. 1014-1022. ISSN 1756-5901

Liu, Zhe (Researcher in chemistry) and Sadler, P. J.. (2014) Organoiridium complexes : anticancer agents and catalysts. Accounts of Chemical Research, Volume 47 (Number 4). pp. 1174-1185. ISSN 0001-4842

Liu, Zhe (Researcher in chemistry) and Sadler, P. J.. (2014) Organoiridium complexes : anticancer agents and catalysts. Accounts of chemical research, 47 (4). pp. 1174-1185. ISSN 0001-4842

Barry, Nicolas P. E., Kemp, Thomas F., Sadler, P. J. and Hanna, John V.. (2014) A multinuclear 1H, 13C and 11B solid-state MAS NMR study of 16- and 18-electron organometallic ruthenium and osmium carborane complexes. Dalton Transactions, Volume 43 (Number 13). pp. 4945-4949. ISSN 1477-9226

Liu, Zhe (Researcher in chemistry), Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J.. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. ISSN 1433-7851

2013

Zhao, Yao, (Researcher in chemistry), Farrer, Nicola J., Li, Huilin, Butler, Jennifer S. (Jennifer Suzanne), McQuitty, Ruth J., Habtemariam, Abraha, Wang, Fuyi and Sadler, P. J.. (2013) De novo generation of singlet oxygen and ammine ligands by photoactivation of a platinum anticancer complex. Angewandte Chemie International Edition, Volume 52 (Number 51). pp. 13633-13637. ISSN 1433-7851

Barry, Nicolas P. E., Deeth, Robert J., Clarkson, Guy J., Prokes, Ivan and Sadler, P. J.. (2013) Thermochromic organometallic complexes: experimental and theoretical studies of 16- to 18-electron interconversions of adducts of arene Ru(ii) carboranes with aromatic amine ligands. Dalton Transactions, Volume 42 (Number 7). pp. 2580-2587. ISSN 1477-9226

Barnett, James P., Dr., Blindauer, Claudia A., Kassaar, Omar, Khazaipoul, Siavash, Martin, Esther M., Sadler, P. J. and Stewart, Alan J. S.. (2013) Allosteric modulation of zinc speciation by fatty acids. Biochimica et Biophysica Acta (BBA) - General Subjects, Volume 830 (Number 12). ISSN 0304-4165

Lin, Yu, Huang, Yongdong, Zheng, Wei, Wang, Fuyi, Habtemariam, Abraha, Luo, Qun, Li, Xianchan, Wu, Kui, Sadler, P. J. and Xiong, Shaoxiang. (2013) Organometallic ruthenium anticancer complexes inhibit human glutathione-S-transferase π. Journal of Inorganic Biochemistry, Volume 128 . pp. 77-84. ISSN 0162-0134

Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J.. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. ISSN 0947-6539

Wang, Fuyi, Xu, Jingjing, Wu, Kui, Weidt, Stefan K., Mackay, C. Logan, Langridge-Smith, Pat R. R. and Sadler, P. J.. (2013) Competition between glutathione and DNA oligonucleotides for ruthenium(ii) arene anticancer complexes. Dalton Transactions, Volume 42 (Number 9). pp. 3188-3195. ISSN 1477-9226

Smith, Nicola A. and Sadler, P. J.. (2013) Photoactivatable metal complexes : from theory to applications in biotechnology and medicine. Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, Volume 371 (Number 1995). p. 20120519. ISSN 1364-503X

Barry, Nicolas P. E. and Sadler, P. J.. (2013) Challenges for metals in medicine : how nanotechnology may help to shape the future. ACS Nano, Volume 7 (Number 7). pp. 5654-5659. ISSN 1936-0851

Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J.. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. ISSN 0947-6539

Hearn, Jessica M., Romero-Canelón, Isolda, Qamar, Bushra, Liu, Zhe (Researcher in chemistry), Hands-Portman, Ian and Sadler, P. J.. (2013) Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis. ACS Chemical Biology, Volume 8 (Number 6). pp. 1335-1343. ISSN 1554-8929

Cubillas, Ana M., Unterkofler, Sarah, Euser, Tijmen G., Etzold, Bastian J. M., Jones, Anita C., Sadler, P. J., Wasserscheid, Peter and Russell, Philip St.J.. (2013) Photonic crystal fibres for chemical sensing and photochemistry. Chemical Society Reviews . ISSN 0306-0012

Barry, Nicolas P. E. and Sadler, P. J.. (2013) Exploration of the medical periodic table : towards new targets. Chemical Communications, Volume 49 (Number 45). pp. 5106-5131. ISSN 1359-7345

Borfecchia, Elisa, Garino, Claudio, Salassa, Luca, Ruiu, Tiziana, Gianolio, Diego, Zhang, Xiaoyi, Attenkofer, Klaus, Chen, Lin X., Gobetto, Roberto, Sadler, P. J. and Lamberti, Carlo. (2013) X-ray transient absorption structural characterization of the 3MLCT triplet excited state of cis-[Ru(bpy)2(py)2]2+. Dalton Transactions, Volume 42 (Number 18). pp. 6564-6571. ISSN 1477-9226

Liu, Zhe (Researcher in chemistry), Deeth, Robert J., Butler, Jennifer S. (Jennifer Suzanne), Habtemariam, Abraha, Newton, Mark E. and Sadler, P. J.. (2013) Reduction of quinones by NADH catalyzed by organoiridium complexes. Angewandte Chemie International Edition, Volume 52 (Number 15). pp. 4194-4197. ISSN 1433-7851

Butler, Jennifer S. (Jennifer Suzanne) and Sadler, P. J.. (2013) Targeted delivery of platinum-based anticancer complexes. Current Opinion in Chemical Biology, Volume 17 (Number 2). pp. 175-188. ISSN 1367-5931

Scotcher, Jenna, Clarke, David J., Mackay, C. Logan, Hupp, Ted R., Sadler, P. J. and Langridge-Smith, Pat R. R.. (2013) Redox regulation of tumour suppressor protein p53 : identification of the sites of hydrogen peroxide oxidation and glutathionylation. Chemical Science, Volume 4 (Number 3). pp. 1257-1269. ISSN 2041-6520

Wu, Kui, Hu, Wenbing, Luo, Qun, Li, Xianchan, Xiong, Shaoxiang, Sadler, P. J. and Wang, Fuyi. (2013) Competitive binding sites of a ruthenium arene anticancer complex on oligonucleotides studied by mass spectrometry : ladder-sequencing versus top-down. Journal of The American Society for Mass Spectrometry, Volume 24 (Number 3). pp. 410-420. ISSN 1044-0305

Barone, Carmen R., Coletti, Cecilia, McQuitty, Ruth J., Farrer, Nicola J., Lorusso, Giuseppe, Maresca, Luciana, Marrone, Alessandro, Natile, Giovanni, Pacifico, Concetta, Parsons, Simon, Re, Nazzareno, Sadler, P. J. and White, Fraser J.. (2013) Photo-isomerisation of alkenyl complexes of platinum(ii) : structural, spectroscopic, kinetic and computational investigations. Dalton Transactions, Volume 42 (Number 19). pp. 6840-6851. ISSN 1477-9226

Pizarro, Ana M. and Sadler, P. J. (2013) Cancer chemistry : designing new drugs for cancer treatment. In: Pelengaris , Stella and Khan, Mike, (eds.) The molecular biology of cancer : a bridge from bench to bedside, 2nd Edition. Hoboken, NJ: Wiley-Blackwell. ISBN 9781118022870

Betanzos-Lara, Soledad, Habtemariam, Abraha and Sadler, P. J.. (2013) Transfer hydrogenation reactions of photoactivatable N, N '-chelated ruthenium(II) arene complexes. Mexican Chemical Society Journal, Volume 57 (Number 3). pp. 160-168. ISSN 1870-249X

Romero-Canelón, Isolda, Salassa, Luca and Sadler, P. J.. (2013) The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes : control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway. Journal of Medicinal Chemistry, Volume 56 (Number 3). pp. 1291-1300. ISSN 0022-2623

2012

Garino, Claudio, Gallo, Erik, Smolentsev, Nikolay, Glatzel, Pieter, Gobetto, Roberto, Lamberti, Carlo, Sadler, P. J. and Salassa, Luca. (2012) Resonant X-ray emission spectroscopy reveals d–d ligand-field states involved in the self-assembly of a square-planar platinum complex. Physical Chemistry Chemical Physics, Vol.14 (No.44). pp. 15278-15281. ISSN 1463-9076

Zhao, Y., Roberts, Gareth M., Greenough, Simon E., Farrer, Nicola J., Peterson, Martin J. , Powell, William H., Stavros, Vasilios G. and Sadler, P. J.. (2012) Two-photon-activated ligand exchange in platinum(II) complexes. Angewandte Chemie International Edition, Vol.51 (No.45). pp. 11263-11266. ISSN 1521-3773

Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha. (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. ISSN 0949-8257

Li, Huilin, Wells, Stephen A., Jimenez-Roldan, J. Emilio, Römer, Rudolf A., Zhao, Yao, (Researcher in chemistry), Sadler, P. J. and O'Connor, Peter B.. (2012) Protein flexibility is key to cisplatin crosslinking in calmodulin. Protein Science, Volume 21 (Number 9). pp. 1269-1279. ISSN 0961-8368

Barragán, Flavia, Carrion-Salip, Dolors, Gómez-Pinto, Irene, González-Cantó, Alejandro, Sadler, P. J., de Llorens, Rafael, Moreno, Virtudes, González, Carlos A., Massaguer, Anna and Marchán, Vicente. (2012) Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes. Bioconjugate Chemistry, Vol.23 (No.9). pp. 1838-1855. ISSN 1043-1802

Soldevila-Barreda, Joan J., Bruijnincx, Pieter C. A., Habtemariam, Abraha, Clarkson, Guy J., Deeth, Robert J. and Sadler, P. J.. (2012) Improved catalytic activity of ruthenium–arene complexes in the reduction of NAD+. Organometallics, Vol.31 (No.16). pp. 5958-5967. ISSN 0276-7333

Unterkofler, S., McQuitty, Ruth J., Euser, T. G., Farrer, Nicola J., Sadler, P. J. and Russell, P. St.J.. (2012) Microfluidic integration of photonic crystal fibers for online photochemical reaction analysis. Optics Letters, Volume 37 (Number 11). pp. 1952-1954. ISSN 0146-9592

Noffke, Anna Louise, Habtemariam, Abraha, Pizarro, Ana M. and Sadler, P. J.. (2012) Designing organometallic compounds for catalysis and therapy. Chemical Communications, Vol.48 (No.43). pp. 5219-5246. ISSN 1359-7345

Lu, Jin, Stewart, Alan J., Sadler, P. J., Pinheiro, Teresa J. T. and Blindauer, Claudia A.. (2012) Allosteric inhibition of cobalt binding to albumin by fatty acids : implications for the detection of myocardial ischemia. Journal of Medicinal Chemistry, Vol.55 (No.9). pp. 4425-4430. ISSN 0022-2623

Mukherjee, Arindam, Bilton, Paul R., Mackay, Logan, Janoschka, Adam, Zhu, Haizhong, Rea, Dean, Langridge-Smith, Pat R. R., Campopiano, Dominic J., Teschner, Thomas, Trautwein, Alfred, Schünemann, Volker and Sadler, P. J.. (2012) Ferric ion (hydr)oxo clusters in the “Venus flytrap” cleft of FbpA : Mössbauer, calorimetric and mass spectrometric studies. JBIC Journal of Biological Inorganic Chemistry, Vol.17 (No.4). pp. 573-588. ISSN 0949-8257

Booyjzsen, Claire, Scarff, Charlotte A., Moreton, Ben, Portman, Ian J., Scrivens, James H., Costantini, Giovanni and Sadler, P. J.. (2012) Fibrillation of transferrin. Biochimica et Biophysica Acta (BBA) - General Subjects, Vol.1820 (No.3). pp. 427-436. ISSN 0304-4165

Lu, Jin, Stewart, Alan J, Sleep, Darrell, Sadler, P. J., Pinheiro, Teresa J. T. and Blindauer, Claudia A.. (2012) A molecular mechanism for modulating plasma Zn speciation by fatty acids. Journal of the American Chemical Society, Vol.134 (No.3). pp. 1454-1457. ISSN 1520-5126

Tai, Hui-Chung, Brodbeck, Ralf, Kasparkova, Jana, Farrer, Nicola J., Brabec, V. (Viktor), Sadler, P. J. and Deeth, Robert J.. (2012) Combined theoretical and computational study of interstrand DNA guanine–guanine cross-linking bytrans-[Pt(pyridine)2] derived from the photoactivated prodrugtrans,trans,trans-[Pt(N3)2(OH)2(pyridine)2]. Inorganic Chemistry, Vol.51 (No.12). pp. 6830-6841. ISSN 0020-1669

Romero-Canelón, Isolda, Pizarro, Ana M., Habtemariam, Abraha and Sadler, P. J.. (2012) Contrasting cellular uptake pathways for chlorido and iodido iminopyridine ruthenium arene anticancer complexes. Metallomics, Volume 4 (Number 12). pp. 1271-1279. ISSN 1756-5901

Ragazzon, Giulio, Bratsos, Ioannis, Alessio, E. (Enzo), Salassa, Luca, Habtemariam, Abraha, McQuitty, Ruth J., Clarkson, Guy J. and Sadler, P. J.. (2012) Design of photoactivatable metallodrugs : selective and rapid light-induced ligand dissociation from half-sandwich [Ru([9]aneS3)(N–N′)(py)]2+ complexes. Inorganica Chimica Acta, Vol.393 . pp. 230-238. ISSN 0020-1693

Barry, Nicolas P. E. and Sadler, P. J.. (2012) Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium : biological relevance and synthetic strategies. Chemical Society Reviews, Vol.41 (No.8). pp. 3264-3279. ISSN 0306-0012

Pracharova, Jitka, Zerzankova, Lenka, Stepankova, Jana, Novakova, Olga, Farrer, Nicola J., Sadler, P. J., Brabec, V. (Viktor) and Kasparkova, Jana. (2012) Interactions of DNA with a new Platinum(IV) Azide Dipyridine complex activated by UVA and visible light : relationship to toxicity in tumor cells. Chemical Research in Toxicology, Vol.25 (No.5). pp. 1099-1111. ISSN 0893-228X

Wu, Kui, Luo, Qun, Hu, Wenbing, Li, Xianchan, Wang, Fuyi, Xiong, Shaoxiang and Sadler, P. J.. (2012) Mechanism of interstrand migration of organoruthenium anticancer complexes within a DNA duplex. Metallomics, Vol.4 (No.2). pp. 139-148. ISSN 1756-5901

Betanzos-Lara, Soledad, Liu, Zhe (Researcher in chemistry), Habtemariam, Abraha, Pizarro, Ana M., Qamar, Bushra and Sadler, P. J.. (2012) Organometallic ruthenium and iridium transfer-hydrogenation catalysts using coenzyme NADH as a cofactor. Angewandte Chemie International Edition, Vol.51 (No.16). pp. 3897-3900. ISSN 1433-7851

Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J.. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. ISSN 0276-7333

Westendorf, A. F., Woods, J. A., Korpis, K., Farrer, Nicola J., Salassa, Luca, Robinson, K., Appleyard, V., Murray, K., Grunert, R., Thompson, A. M., Sadler, P. J. and Bednarski, P. J.. (2012) Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)] : a light-activated antitumor platinum complex that kills human cancer cells by an apoptosis-independent mechanism. Molecular Cancer Therapeutics, Vol.11 (No.9). pp. 1894-1904. ISSN 1535-7163

Butler, Jennifer S. (Jennifer Suzanne), Woods, Julie A., Farrer, Nicola J., Newton, Mark E. and Sadler, P. J.. (2012) Tryptophan switch for a photoactivated platinum anticancer complex. Journal of the American Chemical Society, Vol.134 (No.40). pp. 16508-16511. ISSN 0002-7863

Ross, Allison, Choi, Jong-Ha, Hunter, Tina M., Pannecouque, Christophe, Moggach, Stephen A., Parsons, Simon, De Clercq, Erik and Sadler, P. J.. (2012) Zinc(ii) complexes of constrained antiviral macrocycles. Dalton Transactions, Volume 41 (Number 21). pp. 6408-6418. ISSN 1477-9226

Tai, Hui-Chung, Zhao, Y., Farrer, Nicola J., Anastasi, Anna E., Clarkson, Guy J., Sadler, P. J. and Deeth, Robert J.. (2012) A computational approach to tuning the photochemistry of platinum(IV) anticancer agents. Chemistry - A European Journal, Vol.18 (No.34). pp. 10630-10642. ISSN 0947-6539

Fu, Y. (Ying), Romero, Maria, Habtemariam, Abraha, Snowden, Michael E., Song, Lijiang, Clarkson, Guy J., Qamar, Bushra, Pizarro, Ana M., Unwin, Patrick R. and Sadler, P. J.. (2012) The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexes. Chemical Science, Vol.3 (No.8). pp. 2485-2494. ISSN 2041-6520

2011

Han, Yumiao, Luo, Qun, Hao, Xiang, Li, Xianchan, Wang, Fuyi, Hu, Wenbing, Wu, Kui, Lü, Shuang and Sadler, P. J.. (2011) Reactions of an organoruthenium anticancer complex with 2-mercaptobenzanilide — a model for the active-site cysteine of protein tyrosine phosphatase 1B. Dalton Transactions, Vol.40 (No.43). pp. 11519-11529. ISSN 1477-9226

Ronconi, Luca, Pizarro, Ana M., McQuitty, Ruth J. and Sadler, P. J.. (2011) Insights into the acid-base properties of PtIV-diazidodiam(m)inedihyroxido complexes from multinuclear NMR spectroscopy. Chemistry - A European Journal, Volume 17 (Number 43). pp. 12051-12058. ISSN 0947-6539

Farrer, Nicola J., Gierth, Peter and Sadler, P. J.. (2011) Probing platinum azido complexes by 14N and 15N NMR spectroscopy. Chemistry - A European Journal, Vol.17 (No.43). pp. 12059-12066. ISSN 0947-6539

Fu, Ying, Shnyder, Steve D., Habtemariam, Abraha, Clarkson, Guy J., Cooper, Patricia A., Loadman, Paul M., Pizarro, Ana M. and Sadler, P. J. (2011) Organometallic osmium arene anticancer complexes. In: 242nd National Meeting of the American-Chemical-Society (ACS), Denver, CO, 28 Aug - 1 Sep 2011. Published in: American Chemical Society. Abstracts of Papers (at the National Meeting), Vol.242 17-BIOL.

Liu, Zhe (Researcher in chemistry), Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J.. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. ISSN 0276-7333

Shnyder, Steve D., Fu, Y. (Ying), Habtemariam, Abraha, Rijt, Sabine H. van, Cooper, Patricia A., Loadman, Paul M. and Sadler, P. J.. (2011) Anti-colorectal cancer activity of an organometallic osmium arene azopyridine complex. MedChemComm, Vol.2 (No.7). pp. 666-668. ISSN 2040-2503

Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J.. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. ISSN 1434-1948

Hu, Wenbing, Luo, Qun, Wu, Kui, Li, Xianchan, Wang, Fuyi, Chen, Yi, Ma, Xiaoyan, Wang, Jianping, Liu, Jianan, Xiong, Shaoxiang and Sadler, P. J.. (2011) The anticancer drug cisplatin can cross-link the interdomain zinc site on human albumin. Chemical Communications, Vol.47 (No.21). pp. 6006-6008. ISSN 1359-7345

Liu, Zhe (Researcher in chemistry), Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J.. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. ISSN 0020-1669

Li, Huilin, Zhao, Yao, Phillips, Hazel I. A., Qi, Yulin, Lin, Tzu-Yung, Sadler, P. J. and O'Connor, Peter B.. (2011) Mass spectrometry evidence for cisplatin as a protein cross-linking reagent. Analytical Chemistry, Vol.83 (No.13). pp. 5369-5376. ISSN 0003-2700

Scotcher, Jenna, Clarke, D. J., Weidt, Stefan K., Mackay, C. Logan, Hupp, Theodore, Sadler, P. J. and Langridge-Smith, Pat R. R.. (2011) Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry. Journal of The American Society for Mass Spectrometry, Vol.22 (No.5). pp. 888-897. ISSN 1044-0305

Westendorf, Aron, Zerzankova, Lenka, Salassa, Luca, Sadler, P. J., Brabec, V. (Viktor) and Bednarski, Patrick J.. (2011) Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)]. Journal of Inorganic Biochemistry, Vol.105 (No.5). pp. 652-662. ISSN 01620134

Liu, Zhe (Researcher in chemistry), Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J.. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. ISSN 0022-2623

Booyjzsen, Claire, Scarff, Charlotte A., Moreton, Ben, Portman, Ian J., Costantini, Giovanni, Scrivens, James H., Mukherjee, Arindam and Sadler, P. J. (2011) Human transferrin : association and fibril formation. American Chemical Society. Abstracts of Papers (at the National Meeting), Vol.241 (No.171-BIOL ). ISSN 0065-7727

Ronconi, Luca and Sadler, P. J.. (2011) Photoreaction pathways for the anticancer complex trans,trans,trans-[Pt(N3)2(OH)2(NH3)2]. Dalton Transactions, Vol.40 (No.1). pp. 262-268. ISSN 1477-9226

Kisova, Anna, Zerzankova, Lenka, Habtemariam, Abraha, Sadler, P. J., Brabec, V. (Viktor) and Kasparkova, Jana. (2011) Differences in the cellular response and signaling pathways between cisplatin and monodentate organometallic Ru(II) antitumor complexes containing a terphenyl ligand. Molecular Pharmaceutics, Vol.8 (No.3). pp. 949-957. ISSN 1543-8384

Rijt, Sabine H. van, Kostrhunova, Hana, Brabec, V. (Viktor) and Sadler, P. J.. (2011) Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity. Bioconjugate Chemistry, Vol.22 (No.2). pp. 218-226. ISSN 1043-1802

Farrer, Nicola J. and Sadler, P. J. (2011) Medicinal inorganic chemistry : state of the art, new trends, and a vision of the future. In: Alessio, E. (Enzo) , (ed.) Bioinorganic medicinal chemistry. Weinheim : Chichester: Wiley-VCH : John Wiley [distributor], pp. 1-48. ISBN 9783527326310

Liu, Hong-Ke and Sadler, P. J.. (2011) Metal complexes as DNA intercalators. Accounts of Chemical Research, Vol.44 (No.5). pp. 349-359. ISSN 0001-4842

Barragán, Flavia, López-Senín, Paula, Salassa, Luca, Betanzos-Lara, Soledad, Habtemariam, Abraha, Moreno, Virtudes, Sadler, P. J. and Marchán, Vicente. (2011) Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex. Journal of the American Chemical Society, Vol.133 (No.35). pp. 14098-14108. ISSN 0002-7863

Han, Yumiao, Luo, Qun, Hao, Xiang, Li, Xianchan, Wang, Fuyi, Hu, Wenbing, Wu, Kui, Lü, Shuang and Sadler, P. J.. (2011) Reactions of an organoruthenium anticancer complex with 2-mercaptobenzanilide—a model for the active-site cysteine of protein tyrosine phosphatase 1B. Dalton Transactions, Vol.40 (No.43). pp. 11519-11529. ISSN 1477-9226

Fu, Y. (Ying), Habtemariam, Abraha, Basri, Aida M. B. H., Braddick, Darren, Clarkson, Guy J. and Sadler, P. J.. (2011) Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity. Dalton Transactions (No.40). pp. 10553-10562. ISSN 1477-9226

Li, Huilin, Lin, Tzu-Yung, Van Orden, Steve L., Zhao, Yao, (Researcher in chemistry), Barrow, Mark P., Pizarro, Ana M., Qi, Yulin, Sadler, P. J. and O’Connor, Peter B.. (2011) Use of top-down and bottom-up fourier transform ion cyclotron resonance mass spectrometry for mapping calmodulin sites modified by platinum anticancer drugs. Analytical Chemistry, Vol.83 (No.24). pp. 9507-9515. ISSN 0003-2700

2010

Salassa, Luca, Borfecchia, Elisa, Ruiu, Tiziana, Garino, Claudio, Gianolio, Diego, Gobetto, Roberto, Sadler, P. J., Cammarata, Marco, Wulff, Michael and Lamberti, Carlo. (2010) Photo-induced pyridine substitution in cis-[Ru(bpy)(2)(py)(2)]Cl-2 : a snapshot by time-resolved X-ray solution scattering. Inorganic Chemistry, Vol.49 (No.23). pp. 11240-11248. ISSN 0020-1669

Salassa, Luca, Ruiu, Tiziana, Garino, Claudio, Pizarro, Ana M., Bardelli, Fabrizio, Gianolio, Diego, Westendorf, Aron, Bednarski, Patrick J., Lamberti, Carlo, Gobetto, Roberto and Sadler, P. J.. (2010) EXAFS, DFT, light-induced nucleobase binding, and cytotoxicity of the photoactive complex cis-[Ru(bpy)2(CO)Cl]+. Organometallics, Vol.29 (No.4). pp. 6703-6710. ISSN 0276-7333

Fu, Y. (Ying), Habtemariam, Abraha, Pizarro, Ana M., Rijt, Sabine H. van, Healey, David J., Cooper, Patricia A., Shnyder, Steven D., Clarkson, Guy J. and Sadler, P. J.. (2010) Organometallic osmium arene complexes with potent cancer cell cytotoxicity. Journal of Medicinal Chemistry, Vol.53 (No.22). pp. 8192-8196. ISSN 0022-2623

Farrer, Nicola J., Woods, Julie A., Salassa, Luca, Zhao, Yao, (Researcher in chemistry), Robinson, Kim S., Clarkson, Guy J., Mackay, Fiona S. and Sadler, P. J.. (2010) A potent trans-diimine platinum anticancer complex photoactivated by visible light. Angewandte Chemie International Edition, Vol.49 (No.47). pp. 8905-8908. ISSN 1433-7851

Cubo, Leticia, Pizarro, Ana M., Quiroga, Adoracion G., Salassa, Luca, Navarro-Ranninger, Carmen and Sadler, P. J.. (2010) Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides. Journal of Inorganic Biochemistry, Vol.104 (No.9). pp. 909-918. ISSN 0162-0134

Williams, Jonathan P., Brown, Jeffery M., Campuzano, Iain and Sadler, P. J.. (2010) Identifying drug metallation sites on peptides using electron transfer dissociation (ETD), collision induced dissociation (CID) and ion mobility-mass spectrometry (IM-MS). Chemical Communications, Vol.46 (No.30). pp. 5458-5460. ISSN 1359-7345

Liu, Hong-Ke, Parkinson, J. A. (John A.), Bella, Juraj, Wang, Fuyi and Sadler, P. J.. (2010) Penetrative DNA intercalation and G-base selectivity of an organometallic tetrahydroanthracene Ru-II anticancer complex. Chemical Science, Vol.1 (No.2). pp. 258-270. ISSN 2041-6520

Williams, Jonathan P., Phillips, Hazel I. A., Campuzano, Iain and Sadler, P. J.. (2010) Shape changes induced by N-terminal platination of ubiquitin by cisplatin. Journal of The American Society for Mass Spectrometry, Vol.21 (No.7). pp. 1097-1106. ISSN 1044-0305

Novakova, Olga, Malina, J. (Jaroslav), Suchankova, Tereza, Kasparkova, Jana, Bugarcic, Tijana, Sadler, P. J. and Brabec, V. (Viktor). (2010) Energetics, conformation, and recognition of DNA duplexes modified by monodentate Ru-II complexes containing terphenyl arenes. Chemistry - A European Journal, Vol.16 (No.19). pp. 5744-5754. ISSN 0947-6539

Chen, Jocelyn S. Y., Euser, Tijmen G., Farrer, Nicola J., Sadler, P. J., Scharrer, Michael and Russell, Philip St. J.. (2010) Photochemistry in photonic crystal fiber nanoreactors. Chemistry - A European Journal, Vol.16 (No.19). pp. 5607-5612. ISSN 0947-6539

Pizarro, Ana M., Melchart, Michael, Habtemariam, Abraha, Salassa, Luca, Fabbiani, Francesca P. A., Parsons, S. (Simon) and Sadler, P. J.. (2010) Controlling the reactivity of ruthenium(II) arene complexes by tether ring-opening. Inorganic Chemistry, Vol.49 (No.7). pp. 3310-3319. ISSN 0020-1669

Ruiu, Tiziana, Garino, Claudio, Salassa, Luca, Pizarro, Ana M., Nervi, Carlo, Gobetto, Roberto and Sadler, P. J.. (2010) Spectroscopic and computational study of ligand photodissociation from [Ru(dipyrido[3,2-a:2',3'-c]phenazine)(4-aminopyridine)(4)](2+). European Journal of Inorganic Chemistry, Vol.2010 (No.8). pp. 1186-1195. ISSN 1434-1948

Ross, Allison, Soares, Dinesh C., Covelli, Danielle, Pannecouque, Christophe, Budd, Laura, Collins, Anna, Robertson, N. (Neil), Parsons, S. (Simon), De Clercq, Erik, Kennepohl, Pierre and Sadler, P. J.. (2010) Oxovanadium(IV) cyclam and bicyclam complexes : potential CXCR4 receptor antagonists. Inorganic Chemistry, Vol.49 (No.3). pp. 1122-1132. ISSN 0020-1669

Farrer, Nicola J., Woods, Julie A., Munk, Vivienne P., Mackay, Fiona S. and Sadler, P. J.. (2010) Photocytotoxic trans-Diam(m)ine platinum(IV) diazido complexes more potent than their cis isomers. Chemical Research in Toxicology, Vol.23 (No.2). pp. 413-421. ISSN 0893-228X

Rijt, Sabine H. van, Mukherjee, Arindam, Pizarro, Ana M. and Sadler, P. J.. (2010) Cytotoxicity, hydrophobicity, uptake, and distribution of osmium(II) anticancer complexes in ovarian cancer cells. Journal of Medicinal Chemistry, Vol.53 (No.2). pp. 840-849. ISSN 0022-2623

Bergamo, A., Masi, A., Peacock, Anna F. A., Habtemariam, Abraha, Sadler, P. J. and Sava, G.. (2010) In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model. Journal of Inorganic Biochemistry, Vol.104 (No.1). pp. 79-86. ISSN 0162-0134

Pizarro, Ana M., Habtemariam, Abraha and Sadler, P. J. (2010) Activation mechanisms for organometallic anticancer complexes. In: Jaouen, Gérard and Metzler-Nolte, Nils, (eds.) Medicinal organometallic chemistry. Topics in Organometallic Chemistry, Vol.32 . Berlin ; New York: Springer-Verlag, pp. 21-56. ISBN 9783642131844

Habtemariam, Abraha, Betanzos-Lara, Soledad and Sadler, P. J. (2010) Di-μ-chloro(ethylbenzoate)diruthenium(II) : [(η6-etb)RuCl2]2. In: Inorganic Syntheses. Inorganic Syntheses, Vol.35 . Hoboken, NJ: John Wiley & Sons, Inc., pp. 160-163. ISBN 9780471682554

Shi, Yanbo, Harvey, Ian, Campopiano, Dominic and Sadler, P. J.. (2010) Niobium uptake and release by bacterial ferric ion binding protein. Bioinorganic Chemistry and Applications . ISSN 1565-3633

Farrer, Nicola J., Monk , Nicholas, Heron, Jonathan, Lough, Julie Ann and Sadler, P. J.. (2010) (RSC)(2) : chemistry, performance, and pedagogy - an interactive approach to periodic trends. Chemistry Education Research and Practice, Vol.11 (No.4). pp. 308-313. ISSN 1109-4028

2009

Rijt, Sabine H. van, Hebden, Andrew J., Amaresekera, Thakshila, Deeth, Robert J., Clarkson, Guy J., Parsons, S. (Simon), McGowan, Patrick C. and Sadler, P. J.. (2009) Amide linkage isomerism as an activity switch for organometallic osmium and ruthenium anticancer complexes. Journal of Medicinal Chemistry, Vol.52 (No.23). pp. 7753-7764. ISSN 0022-2623

Rijt, Sabine H. van and Sadler, P. J.. (2009) Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs. Drug Discovery Today, Vol.14 (No.23-24). pp. 1089-1097. ISSN 1359-6446

Salassa, Luca, Phillips, Hazel I. A. and Sadler, P. J.. (2009) Decomposition pathways for the photoactivated anticancer complex cis,trans,cis-[Pt(N-3)(2)(OH)(2)(NH3)(2)] : insights from DFT calculations. Physical Chemistry Chemical Physics, Vol.11 (No.44). pp. 10311-10316. ISSN 1463-9076

Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha and Sadler, P. J.. (2009) Photocontrolled nucleobase binding to an organometallic Ru-II arene complex. Chemical Communications (No.43). pp. 6622-6624. ISSN 1359-7345

Stewart, Alan J., Blindauer, Claudia A. and Sadler, P. J.. (2009) Plasma fatty acid levels may regulate the Zn2+-dependent activities of histidine-rich glycoprotein. Biochimie, Vol.91 (No.11-12). pp. 1518-1522. ISSN 0300-9084

Williams, Jonathan P., Lough, Julie Ann, Campuzano, Iain, Richardson, K. (Keith) and Sadler, P. J.. (2009) Use of ion mobility mass spectrometry and a collision cross-section algorithm to study an organometallic ruthenium anticancer complex and its adducts with a DNA oligonucleotide. Rapid Communications in Mass Spectrometry, Vol.23 (No.22). pp. 3563-3569. ISSN 09514198

Bugarcic, Tijana, Habtemariam, Abraha, Deeth, Robert J., Fabbiani, Francesca P. A., Parsons, S. (Simon) and Sadler, P. J.. (2009) Ruthenium(II) arene anticancer complexes with redox-active diamine ligands. Inorganic Chemistry, Vol.48 (No.19). pp. 9444-9453. ISSN 0020-1669

Pizarro, Ana M. and Sadler, P. J.. (2009) Unusual DNA binding modes for metal anticancer complexes. Biochimie, Vol.91 (No.10). pp. 1198-1211. ISSN 0300-9084

Sriskandakumar, Thamayanthy, Petzold, Holm, Bruijnincx, Pieter C. A., Habtemariam, Abraha, Sadler, P. J. and Kennepohl, Pierre. (2009) Influence of oxygenation on the reactivity of ruthenium-thiolato bonds in arene anticancer complexes: insights from XAS and DFT. Journal of the American Chemical Society, Vol.131 (No.37). pp. 13355-13361. ISSN 0002-7863

Newstead, Simon, Fowler, Philip W., Bilton, Paul R., Carpenter, Elisabeth P., Sadler, P. J., Campopiano, Dominic J., Sansom, M. S. P. (Mark S. P.) and Iwata, So. (2009) Insights into how nucleotide-binding domains power ABC transport. Structure, Vol.17 (NO.9). pp. 1213-1222. ISSN 0969-2126

Mackay, Fiona S., Farrer, Nicola J., Salassa, Luca, Tai, Hui-Chung, Deeth, Robert J., Moggach, Stephen A., Wood, P. A. (Peter A.), Parsons, S. (Simon) and Sadler, P. J.. (2009) Synthesis, characterisation and photochemistry of PtIV pyridyl azido acetato complexes. Dalton Transactions, Vol.13 . pp. 2315-2325. ISSN 1477-9226

Wang, Fuyi, Habtemariam, Abraha, van der Geer, Erwin P. L., Deeth, Robert J., Gould, Robert O., Parsons, Simon and Sadler, P. J.. (2009) Synthesis, characterization, and reaction pathways for the formation of a GMP adduct of a cytotoxic thiocyanato ruthenium arene complex. Journal of Biological Inorganic Chemistry, Vol.14 (No.7). pp. 1065-1076. ISSN 0949-8257

Blindauer, Claudia A., Harvey, Ian, Bunyan, Kerry E., Stewart, Alan J., Sleep, Darrell, Harrison, David J., Berezenko, Stephen and Sadler, P. J.. (2009) Structure, properties, and engineering of the major zinc binding site on human albumin. Journal of Biological Chemistry, Vol.284 (No.34). pp. 23116-23124. ISSN 0021-9258

Hu, Wenbing, Luo, Qun, Ma, Xiaoyan, Wu, Kui, Liu, Jianan, Chen, Yi, Xiong, Shaoxiang, Wang, Jianping, Sadler, P. J. and Wang, Fuyi. (2009) Arene control over thiolate to sulfinate oxidation in albumin by organometallic ruthenium anticancer complexes. Chemistry - A European Journal, Vol.15 (No.27). pp. 6586-6594. ISSN 0947-6539

Williams, Jonathan P., Bugarcic, Tijana, Habtemariam, Abraha, Giles, K. (Kevin), Campuzano, Iain, Rodger, P. Mark and Sadler, P. J.. (2009) Isomer separation and gas-phase configurations of organoruthenium anticancer complexes : ion mobility mass spectrometry and modeling. Journal of The American Society for Mass Spectrometry, Vol.20 (No.6). pp. 1119-1122. ISSN 1044-0305

Gray, Jennifer C., Pagelot, Alain, Collins, Anna, Fabbiani, Francesca P. A., Parsons, S. (Simon) and Sadler, P. J.. (2009) Organometallic osmium(II) and ruthenium(II) biphenyl sandwich complexes : x-ray crystal structures and Os-187 NMR spectroscopic studies in solution. European Journal of Inorganic Chemistry, Vol.2009 (No.18). pp. 2673-2677. ISSN 1434-1948

Diakos, Connie I., Messerle, Barbara A., del Socorro Murdoch, P., Parkinson, J. A. (John A.), Sadler, P. J., Fenton, Ronald R. and Hambley, Trevor W.. (2009) Identification by NMR spectroscopy of the two stereoisomers of the platinum complex [PtCl2(S-ahaz)] (S-ahaz=3(S)-aminohexahydroazepine) bound to a DNA 14-mer oligonucleotide. NMR evidence of structural alteration of a platinated A.T-rich 14-mer DNA duplex. Inorganic Chemistry, Vol.48 (No.7). pp. 3047-3056. ISSN 0020-1669

Sadler, P. J.. (2009) Precious anticancer drugs. Chemistry & Industry (No.5). pp. 18-20. ISSN 0009-3068

Mackay, Fiona S., Moggach, Stephen A., Collins, Anna, Parsons, S. (Simon) and Sadler, P. J.. (2009) Photoactive trans ammine/amine diazido platinum(IV) complexes. Inorganica Chimica Acta, Vol.362 (No.3). pp. 811-819. ISSN 0020-1693

Salassa, Luca, Garino, Claudio, Salassa, Giovanni, Nervi, Carlo, Gobetto, Roberto, Lamberti, Carlo, Gianolio, Diego, Bizzarri, Ranieri and Sadler, P. J.. (2009) Ligand-selective photodissociation from [Ru(bpy)(4AP)(4)](2+) : a spectroscopic and computational study. Inorganic Chemistry, Vol.48 (No.4). pp. 1469-1481. ISSN 0020-1669

Rijt, Sabine H. van, Peacock, Anna F. A., Johnstone, Russell D. L., Parsons, S. (Simon) and Sadler, P. J.. (2009) Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives. Inorganic Chemistry, Vol.48 (No.4). pp. 1753-1762. ISSN 0020-1669

Phillips, Hazel I. A., Ronconi, Luca and Sadler, P. J.. (2009) Photoinduced reactions of cis,trans,cis-[Pt-IV(N-3)(2)(OH)(2)(NH3)(2)] with 1-methylimidazole. Chemistry: A European Journal, Vol.15 (No.7). pp. 1588-1596. ISSN 0947-6539

Sadler, P. J. (2009) Protein recognition of platinated DNA. ChemBioChem, Vol.10 (No.1). pp. 73-74. ISSN 1439-4227

Bruijnincx, Pieter C. A. and Sadler, P. J.. (2009) Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design. Advances in Inorganic Chemistry, Vol.61 . pp. 1-62. ISSN 0898-8838

Sadler, P. J. (2009) Dalton Transactions themed issue on Metal Anticancer Compounds. Dalton Transactions (No.48). p. 10647. ISSN 1477-9226

Pizarro, Ana M. and Sadler, P. J. (2009) Metal ion–nucleic acid interactions in disease and medicine. In: Hud, Nicholas V. (Nicholas Vincent), (ed.) Nucleic Acid-Metal Ion Interactions. RSC biomolecular sciences . Cambridge, UK: Royal Society of Chemistry, pp. 350-416. ISBN 9780854041954

Rijt, Sabine H. van, Peacock, Anna F. A. and Sadler, P. J. (2009) Osmium arenes : a new class of potential anti-cancer agents. In: Bonetti, Andrea, MD and Leone, Roberto and Muggia, Franco M. and Howell, Stephen B., 1944-, (eds.) Platinum and other heavy metal compounds in cancer chemotherapy : molecular mechanisms and clinical applications. Cancer drug discovery and development . Totowa, N.J. : London: Humana : Springer [distributor], pp. 73-79. ISBN 978-1-60327-458-6

Farrer, Nicola J., Salassa, Luca and Sadler, P. J.. (2009) Photoactivated chemotherapy (PACT) : the potential of excited-state d-block metals in medicine. Dalton Transactions, Vol.48 . pp. 10690-10701. ISSN 1477-9226

Salassa, Luca, Gianolio, Diego, Garino, Claudio, Salassa, Giovanni, Borfecchia, Elisa, Ruiu, Tiziana, Nervi, Carlo, Gobetto, Roberto, Bizzarri, Ranieri, Sadler, P. J. and Lamberti, Carlo (2009) Structure of [Ru(bpy)(n)(AP)((6-2n))](2+) homogeneous complexes: DFT calculation vs. EXAFS. In: 14th International Conference on X-Ray Absorption Fine Structure (XAFS14), Camerino, Italy, July 26-31, 2009. Published in: Journal of Physics: Conference Series, Vol.190 Article no. 012141.

2008

Bugarcic, Tijana, Habtemariam, Abraha, Stepankova, Jana, Heringova, Pavla, Kasparkova, Jana, Deeth, Robert J., Johnstone, Russell D. L., Prescimone, Alessandro, Parkin, Andrew, Parsons, S. (Simon), Brabec, V. (Viktor) and Sadler, P. J.. (2008) The contrasting chemistry and cancer cell cytotoxicity of bipyridine and bipyridinediol ruthenium(II) arene complexes. Inorganic Chemistry, Vol.47 (No.24). pp. 11470-11486. ISSN 0020-1669

Lu, Jin, Stewart, Alan J., Sadler, P. J., Pinheiro, Teresa and Blindauer, Claudia A.. (2008) Albumin as a zinc carrier : properties of its high-affinity zinc-binding site. Biochemical Society Transactions, Vol.36 (No.6). pp. 1317-1321. ISSN 0300-5127

Peacock, Anna F. A. and Sadler, P. J. (2008) Medicinal organometallic chemistry : designing metal arene complexes as anticancer agents. Chemistry - An Asian Journal, Vol.3 (No.11). pp. 1890-1899. ISSN 1861-4728

Ronconi, Luca and Sadler, P. J. (2008) Applications of heteronuclear NMR spectroscopy in biological and medicinal inorganic chemistry. Coordination Chemistry Reviews, Vol.252 (No.21-22). pp. 2239-2277. ISSN 0010-8545

Petzold, Holm and Sadler, P. J.. (2008) Oxidation induced by the antioxidant glutathione (GSH). Chemical Communications (No.37). pp. 4413-4415. ISSN 1359-7345

Bugarcic, Tijana, Novakova, Olga, Halamikova, Anna, Zerzankova, Lenka, Vrana, Oldrich, Kasparkova, Jana, Habtemariam, Abraha, Parsons, S. (Simon), Sadler, P. J. and Brabec, V. (Viktor). (2008) Cytotoxicity, cellular uptake, and DNA interactions of new monodentate ruthenium(II) complexes containing terphenyl arenes. Journal of Medicinal Chemistry, Vol.51 (No.17). pp. 5310-5319. ISSN 0022-2623

Gray, Jennifer C., Habtemariam, Abraha, Winnig, Marcel, Meyerhof, Wolfgang and Sadler, P. J.. (2008) Sweetening ruthenium and osmium : organometallic arene complexes containing aspartame. Journal of Biological Inorganic Chemistry, Vol.13 (No.7). pp. 1111-1120. ISSN 0949-8257

Dougan, Sarah J., Habtemariam, Abraha, McHale, Sarah E., Parsons, S. (Simon) and Sadler, P. J.. (2008) Catalytic organometallic anticancer complexes. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.33). pp. 11628-11633. ISSN 0027-8424

Castellano-Castillo, Maria, Kostrhunova, Hana, Marini, Victoria, Kasparkova, Jana, Sadler, P. J., Malinge, Jean-Marc and Brabec, V. (Viktor). (2008) Binding of mismatch repair protein MutS to mispaired DNA adducts of intercalating ruthenium(II) arene complexes. Journal of Biological Inorganic Chemistry, Vol.13 (No.6). pp. 993-999. ISSN 0949-8257

Kostrhunova, Hana, Florian, Jakub, Novakova, Olga, Peacock, Anna F. A., Sadler, P. J. and Brabec, V. (Viktor). (2008) DNA interactions of monofunctional organometallic osmium(II) antitumor complexes in cell-free media. Journal of Medicinal Chemistry, Vol.51 (No.12). pp. 3635-3643. ISSN 0022-2623

Euser, T. G., Chen, J. S. Y., Scharrer, M., Russell, Philip St. J., Farrer, Nicola J. and Sadler, P. J.. (2008) Quantitative broadband chemical sensing in air-suspended solid-core fibers. Journal of Applied Physics, Vol.103 (No.10). p. 103108. ISSN 0021-8979

Blindauer, Claudia A., Harrison, Mark D., Parkinson, J. A. (John A.), Robinson, N. J. (Nigel J.) and Sadler, P. J. (2008) Isostructural replacement of zinc by cadmium in bacterial metallothionein. In: 10th International Symposium on Metal Ions in Biology and Medicine, Bastia, France, 19-22 May 2008. Published in: Metal Ions in Biology and Medicine, Vol.10 pp. 167-173.

Petzold, Holm, Xu, Jingjing and Sadler, P. J.. (2008) Metal and ligand control of sulfenate reactivity : arene ruthenium thiolato-mono-S-oxides. Angewandte Chemie International Edition, Vol.47 (No.16). pp. 3008-3011. ISSN 1433-7851

Wang, Fuyi, Weidt, Stefan, Xu, Jingjing, Mackay, C. Logan, Langridge-Smith, Pat R. R. and Sadler, P. J.. (2008) Identification of clusters from reactions of ruthenium arene anticancer complex with glutathione using nanoscale liquid chromatography fourier transform ion cyclotron mass spectrometry combined with 18O-labeling. Journal of The American Society for Mass Spectrometry, Vol.19 (No.4). pp. 544-549. ISSN 1044-0305

Bruijnincx, Pieter C. A. and Sadler, P. J.. (2008) New trends for metal complexes with anticancer activity. Current Opinion in Chemical Biology, Vol.12 (No.2). pp. 197-206. ISSN 1367-5931

Ghosh, Surajit, Mukherjee, Arindam, Sadler, P. J. and Verma, Sandeep. (2008) Periodic iron nanomineralization in human serum transferrin fibrils. Angewandte Chemie International Edition, Vol.47 (No.12). pp. 2217-2221. ISSN 1433-7851

Ronconi, Luca and Sadler, P. J.. (2008) Unprecedented carbon–carbon bond formation induced by photoactivation of a platinum(iv)-diazido complex. Chemical Communications (2). pp. 235-237. ISSN 1359-7345

Farrer, Nicola J. and Sadler, P. J.. (2008) Photochemotherapy : targeted activation of metal anticancer complexes. Australian Journal of Chemistry, Vol.61 (No.9). pp. 669-674. ISSN 0004-9425

2007

Mackay, Fiona S., Woods, Julie A., Heringova, Pavia, Kasparkova, Jana, Pizarro, Ana M., Moggach, Stephen A., Parsons, Simon, Brabec, V. (Viktor) and Sadler, P. J.. (2007) A potent cytotoxic photoactivated platinum complex. Proceedings of the National Academy of Sciences of the United States of America, Vol.104 (No.52). pp. 20743-20748. ISSN 0027-8424

Melchart, Michael, Habtemariam, Abraha, Novakova, Olga, Moggach, Stephen A., Fabbiani, Francesca P. A., Parsons, Simon, Brabec, V. (Viktor) and Sadler, P. J.. (2007) Bifunctional amine-tethered Ruthenium(II) arene complexes form monofunctional adducts on DNA. Inorganic Chemistry, Vol.46 (No.21). pp. 8950-8962. ISSN 0020-1669

Dougan, Sarah J., Mukherjee, Arindam, Habtemariam, Abraha and Sadler, P. J. (2007) INOR 147-Kinetically-inert organometallic ruthenium arene complexes: A new class of cancer cell cytotoxic agents. In: UNSPECIFIED. Published in: Abstracts of papers of the American Chemical Society, Vol.234

Blindauer, Claudia A., Razi, M. Tahir, Campopiano, Dominic J. and Sadler, P. J.. (2007) Histidine ligands in bacterial metallothionein enhance cluster stability. Journal of Biological Inorganic Chemistry, Vol.12 (No.3). pp. 393-405. ISSN 0949-8257

Peacock, Anna F. A., Melchart, Michael, Deeth, Robert J., Habtemariam, Abraha, Parsons, Simon and Sadler, P. J.. (2007) Osmium(II) and ruthenium(II) arene maltolato complexes : rapid hydrolysis and nucleobase binding. Chemistry : A European Journal, Volume 13 (Number 9). pp. 2601-2613. ISSN 0947-6539

Dougan, Sarah J. and Sadler, P. J.. (2007) The design of organometallic ruthenium arene anticancer agents. Chimia, Volume 61 (Number 11). pp. 704-715. ISSN 0009-4293

2006

Habtemariam, Abraha, Melchart, Michael, Fernández, Rafael, Parsons, Simon, Oswald, Iain D. H., Parkin, Andrew, Fabbiani, Francesca P. A., Davidson, James E., Dawson, Alice, Aird, Rhona E., Jodrell, Duncan I. and Sadler, P. J.. (2006) Structure−activity relationships for cytotoxic ruthenium(II) arene complexes containing N,N-, N,O-, and O,O-chelating ligands. Journal of Medicinal Chemistry, Volume 49 (Number 23). pp. 6858-6868. ISSN 0022-2623

2005

Wang, Fuyi, Xu, Jingjing, Habtemariam, Abraha, Bella, Juraj and Sadler, P. J.. (2005) Competition between glutathione and guanine for a ruthenium(II) arene anticancer complex : detection of a sulfenato intermediate. Journal of the American Chemical Society, Volume 127 (Number 50). pp. 17734-17743. ISSN 0002-7863

2002

Liang, Xiangyang, Parkinson, J. A. (John A.), Weishäupl, Michael, Gould, Robert O., Paisey, Stephen J., Park, Hye-seo, Hunter, Tina M., Blindauer, Claudia A., Parsons, S. (Simon) and Sadler, P. J.. (2002) Structure and dynamics of metallomacrocycles : recognition of zinc xylyl-bicyclam by an HIV coreceptor. Journal of the American Chemical Society, Vol.124 (No.31). pp. 9105-9112. ISSN 0002-7863