2021

Castaldo, Rossana, Chappell, M. J., Byrne, H., Innominato, Pasquale F., Hughes, S., Pescapè, A. and Pecchia, Leandro (2021) Detection of melatonin-onset in real settings via wearable sensors and artificial intelligence : a pilot study. Biomedical Signal Processing and Control, 65 . 102386. doi:10.1016/j.bspc.2020.102386

Komarzynski, Sandra, Wreglesworth, Nicholas I., Griffiths, Dawn, Pecchia, Leandro, Subbe, Christian P., Hughes, Stephen F., Davies, Elin H. and Innominato, Pasquale F. (2021) Embracing change : learnings from implementing multidimensional digital remote monitoring in oncology patients at a district general hospital during the COVID-19 pandemic. JCO Clinical Cancer Informatics (5). pp. 216-220. doi:10.1200/CCI.20.00136 (In Press)

2020

Innominato, Pasquale F., Karaboué, Abdoulaye, Focan, Christian, Chollet, Philippe, Giacchetti, Sylvie, Bouchahda, Mohamed, Ulusakarya, Ayhan, Torsello, Angela, Adam, René, Lévi, Francis A. and Garufi, Carlo (2020) Efficacy and safety of chronomodulated irinotecan, oxaliplatin, 5‐fluorouracil and leucovorin combination as first‐ or second‐line treatment against metastatic colorectal cancer : results from the International EORTC 05011 Trial. International Journal of Cancer . doi:10.1002/ijc.33422 (In Press)

Lévi, Francis A., Komarzynski, Sandra, Huang, Qi, Young, Teresa, Ang, Yeng, Fuller, Claire, Bolborea, Matei, Brettschneider, Julia, Fursse, Joanna, Finkenstädt, Bärbel, White, David Pollard and Innominato, Pasquale F. (2020) Tele-monitoring of cancer patients’ rhythms during daily life identifies actionable determinants of circadian and sleep disruption. Cancers, 12 (7). 1938. doi:10.3390/cancers12071938

Innominato, Pasquale F., Ballesta, Annabelle, Huang, Qi, Focan, Christian, Chollet, Philippe, Karaboué, Abdoulaye, Giacchetti, Sylvie, Bouchahda, Mohamed, Adam, René, Garufi, Carlo and Lévi, Francis A. (2020) Sex-dependent least toxic timing of irinotecan combined with chronomodulated chemotherapy for metastatic colorectal cancer : randomized multicenter. Cancer Medicine, 9 (12). pp. 4148-4159. doi:10.1002/cam4.3056

2019

Komarzynski, Sandra, Huang, Qi, Lévi, Francis A., Palesh, Oxana G., Ulusakarya, Ayhan, Bouchahda, Mohamed, Haydar, Mazen, Wreglesworth, Nicholas I, Morère, Jean-François, Adam, René and Innominato, Pasquale F. (2019) The day after : correlates of patient-reported outcomes with actigraphy-assessed sleep in cancer patients at home (inCASA project). Sleep . zsz146. doi:10.1093/sleep/zsz146 (In Press)

Saffroy, Raphael, Lafaye, Genevieve, Desterke, Christophe, Ortiz-Tudela, Elisabeth, Amirouche, Ammar, Innominato, Pasquale F., Pham, Patrick, Benyamina, Amine and Lemoine, Antoinette (2019) Several clock genes polymorphisms are meaningful risk factors in the development and severity of cannabis addiction. Chronobiology International, 36 (1). pp. 122-134. doi:10.1080/07420528.2018.1523797

2018

Innominato, Pasquale F., Komarzynski, Sandra, Palesh, Oxana G., Dallmann, Robert, Bjarnason, Georg A., Giacchetti , Syvie, Ulusakarya , Ayhan, Bouchahda, Mohamed, Haydar, Mazen, Ballesta, Annabelle, Karaboué, Abdoulaye, Wreglesworth, Nicholas I., Spiegel, David and Lévi, Francis A. (2018) Circadian rest-activity rhythm as an objective biomarker of patient-reported outcomes in patients with advanced cancer. Cancer Medicine, 7 (9). pp. 4396-4405. doi:10.1002/cam4.1711

Komarzynski, Sandra, Huang, Qi, Innominato, Pasquale F., Maurice, Monique, Arbaud, Alexandre, Beau, Jacques, Bouchahda, Mohamed, Ulusakarya, Ayhan, Beaumatin, Nicolas, Breda, Gabrièle, Finkenstädt, Bärbel and Lévi, Francis A. (2018) Relevance of a mobile internet platform for capturing inter- and intrasubject variabilities in circadian coordination during daily routine : pilot study. Journal of Medical Internet Research, 20 (6). e204. doi:10.2196/jmir.9779

Innominato, Pasquale F., Komarzynski, Sandra, Karaboué, Abdoulaye, Ulusakarya, Ayhan, Bouchahda, Mohamed, Haydar, Mazen, Bossevot-Desmaris, Rachel, Mocquery, Magali, Plessis, Virginie and Lévi, Francis A. (2018) Home-based e-Health platform for multidimensional telemonitoring of symptoms, body weight, sleep, and circadian activity : relevance for chronomodulated administration of irinotecan, fluorouracil-leucovorin, and oxaliplatin at home—results From a pilot study. JCO Clinical Cancer Informatics . doi:10.1200/CCI.17.00125

Huang, Qi, Cohen, Dwayne, Komarzynski, Sandra, Li, Xiao-Mei, Innominato, Pasquale F., Lévi, Francis A. and Finkenstädt, Bärbel (2018) Hidden Markov models for monitoring circadian rhythmicity in telemetric activity data. Journal of The Royal Society Interface, 15 (139). doi:10.1098/rsif-2017-0885

2017

Palesh, Oxana, Haitz, Karyn, Lévi, Francis A., Bjarnason, Georg A., Deguzman, Carl, Alizeh, Igbal, Ulusakarya, Ayhan, Packer, Mary Melissa and Innominato, Pasquale F. (2017) Relationship between subjective and actigraphy-measured sleep in 237 patients with metastatic colorectal cancer. Quality of Life Research, 26 (10). pp. 2783-2791. doi:10.1007/s11136-017-1617-2

Garufi, C., Levi, F., Karaboué, A., Torsello, A., Focan, C., Chollet, P. and Innominato, P. (2017) 513PEfficacy and tolerability of chronomodulated FOLFIRINOX (chronoIFLO) as 1st or 2nd line treatment in patients (pts) with metastatic colorectal cancer (MCC) : final results from an international trial (EORTC 05011). Annals of Oncology, 28 (5). doi:10.1093/annonc/mdx393.039

Innominato, P., Komarzynski , S., Bouchahda, M., Ulusakarya, A., Haydar, M., Karaboué, A. and Levi, F. (2017) Multidimensional telemonitoring of cancer patients (pts) receiving chronomodulated (chrono) Irinotecan (I), 5-fluorouracil (F), leucovorin (L) and oxaliplatin (O; chronoIFLO4) combination at home. Annals of Oncology, 28 (5). doi:10.1093/annonc/mdx388.019

Levi, F., Garufi, C., Karaboué, A., Focan, C., Chollet, P., Li, X-M. and Innominato, P. (2017) Sex-related differences in circadian-dependent tolerance of Irinotecan (I) added to chronomodulated (chrono) 5-Fluorouracil (F), Leucovorin (L) and Oxaliplatin (O): Final results from international randomised time-finding study in patients with metastatic colorectal cancer (MCC). Annals of Oncology, 28 (5). doi:10.1093/annonc/mdx393.048

Adam, René, Yi, Bin, Innominato, Pasquale F., Barroso, Eduardo, Laurent, Christophe, Giuliante, Felice, Capussotti, Lorenzo, Lapointe, Réal, Regimbeau, Jean-Marc, Lopez-Ben, Santiago, Isoniemi, Helena, Hubert, Catherine, Lin, Jen-Kou, Gruenberger, Thomas, Elias, Dominique, Skipenko, Oleg G. and Guglielmi, Alfredo (2017) Resection of colorectal liver metastases after second-line chemotherapy : is it worthwhile? A LiverMetSurvey analysis of 6415 patients. European Journal of Cancer, 78 . pp. 7-15. doi:10.1016/j.ejca.2017.03.009

Ballesta, Annabelle, Innominato, Pasquale F., Dallmann, Robert, Rand, D. A. (David A.) and Lévi, Francis A. (2017) Systems chronotherapeutics. Pharmacological Reviews, 69 (2). pp. 161-199. doi:10.1124/pr.116.013441

Saffroy, Raphael, Morère, Jean-François, Bosselut, Nelly, Innominato, Pasquale F., Hamelin, Jocelyne, Trédaniel, Jean, Masse, Sophie, Dussaule-Duchatelle, Véronique, Balaton, André, Validire, Pierre, Guettier, Catherine, Bouchahda, Mohamed and Lemoine, Antoinette (2017) Impact of country of birth on genetic testing of metastatic lung adenocarcinomas in France : African women exhibit a mutational spectrum more similar to Asians than to Caucasians. Oncotarget, 8 . pp. 50792-50803. doi:doi:10.18632/oncotarget.15132

Lévi, Francis A., Karaboué, Abdoulaye, Etienne-Grimaldi, Marie-Christine, Paintaud, Gilles, Focan, Christian, Innominato, Pasquale F., Bouchahda, Mohamed, Milano, Gérard and Chatelut, Etienne (2017) Pharmacokinetics of Irinotecan, Oxaliplatin and 5-Fluorouracil during hepatic artery chronomodulated infusion : a translational European OPTILIV study. Clinical Pharmacokinetics, 56 (2). pp. 165-177. doi:10.1007/s40262-016-0431-2

2016

Innominato, Pasquale F., Komarzynski, Sandra, Mohammad-Djafari, Ali, Arbaud, Alexandre, Ulusakarya, Ayhan, Bouchahda, Mohamed, Haydar, Mazen, Bossevot-Desmaris, Rachel, Plessis, Virginie, Mocquery, Magali, Bouchoucha, Davina, Afshar, Mehran, Beau, Jacques, Karaboué, Abdoulaye, Morère, Jean-François, Fursse, Joanna, Rovira Simon, Jordi and Lévi, Francis A. (2016) Clinical relevance of the first domomedicine platform securing multidrug chronotherapy delivery in metastatic cancer patients at home : the inCASA European project. Journal of Medical Internet Research, 18 (11). e305. doi:10.2196/jmir.6303

(2016) Early tumour response as a survival predictor in previously- treated patients receiving triplet hepatic artery infusion and intravenous cetuximab for unresectable liver metastases from wild-type KRAS colorectal cancer. European Journal of Cancer Care, 68 . pp. 163-172. doi:10.1016/j.ejca.2016.09.011

Ortiz-Tudela, Elisabet, Innominato, Pasquale F., Rol, Maria Angeles, Lévi, Francis A. and Madrid, Juan Antonio (2016) Relevance of internal time and circadian robustness for cancer patients. BMC Cancer, 16 (1). 285. doi:10.1186/s12885-016-2319-9

2015

Natale, Vincenzo, Innominato, Pasquale F., Boreggiani, Michele, Tonetti, Lorenzo, Filardi, Marco, Parganiha, Arti, Fabbri, Marco, Martoni, Monica and Lévi, Francis A. (2015) The difference between in bed and out of bed activity as a behavioral marker of cancer patients : a comparative actigraphic study. Chronobiology International, 32 (7). pp. 925-933. doi:10.3109/07420528.2015.1053909

Innominato, Pasquale F., Spiegel, David, Ulusakarya, Ayhan, Giacchetti, Sylvie, Bjarnason, Georg A., Lévi, Francis A. and Palesh, Oxana (2015) Subjective sleep and overall survival in chemotherapy-naïve patients with metastatic colorectal cancer. Sleep Medicine, 16 (3). pp. 391-398. doi:10.1016/j.sleep.2014.10.022

2014

Lévi, Francis A., Dugué, Pierre-Antoine, Innominato, Pasquale F., Karaboué, Abdoulaye, Dispersyn, Garance, Parganiha, Arti, Giacchetti, Sylvie, Moreau, Thierry, Focan, Christian, Waterhouse, Jim and Spiegel, David (2014) Wrist actimetry circadian rhythm as a robust predictor of colorectal cancer patients survival. Chronobiology International, 31 (8). pp. 891-900. doi:10.3109/07420528.2014.924523