2019

Kosol, Simone, Gallo, Angelo, Griffiths, Daniel, Valentic, Timothy R., Masschelein, Joleen, Jenner, Matthew, de los Santos, Emmanuel L. C., Manzi, Lucio, Sydor, Paulina K., Rea, Dean, Zhou, Shanshan, Füllöp, Vilmos, Oldham, Neil J., Tsai, Shiou-Chuan, Challis, Gregory L. and Lewandowski, Józef R. (2019) Structural basis for chain release from the enacyloxin polyketide synthase. Nature Chemistry, 11 . 913-923 . doi:10.1038/s41557-019-0335-5

de los Santos, Emmanuel L. C. (2019) NeuRiPP : neural network identification of RiPP precursor peptides. Scientific Reports, 9 (1). 13406. doi:10.1038/s41598-019-49764-z

Zhou, Shanshan, Song, Lijiang, Masschelein, Joleen, Sumang, Felaine A. M., Papa, Irene A., Zulaybar, Teofila O., Custodio, Aileen B., Zabala, Daniel, Alcantara, Edwin P., Emmanuel de los Santos, L. C. and Challis, Gregory L. (2019) Pentamycin biosynthesis in Philippine Streptomyces sp. S816 : cytochrome P450-catalyzed installation of the C-14 hydroxyl group. ACS Chemical Biology (14). pp. 1305-1309. doi:10.1021/acschembio.9b00270 (In Press)

2018

Perry, Christopher, de los Santos, Emmanuel L. C., Alkhalaf, Lona M. and Challis, Gregory L. (2018) Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis. Natural Product Reports, 35 (7). pp. 622-632. doi:10.1039/c8np00004b

2017

Bowyer, Jack E., LC. de los Santos, Emmanuel, Styles, Kathryn, Fullwood, Alex, Corre, Christophe and Bates, Declan (2017) Modeling the architecture of the regulatory system controlling methylenomycin production in Streptomyces coelicolor. Journal of Biological Engineering, 11 (1). 30. doi:10.1186/s13036-017-0071-6

Blin, Kai, Wolf, Thomas, Chevrette, Marc G., Lu, Xiaowen, Schwalen, Christopher J., Kautsar, Satria A., Suarez Duran, Hernando G., Emmanuel de los Santos, L. C., Kim, Hyun Uk, Nave, Mariana, Dickschat, Jeroen S., Mitchell, Douglas A., Shelest, Ekaterina, Breitling, Rainer, Takano, Eriko, Lee, Sang Yup, Weber, Tilmann and Medema, Marnix H. (2017) antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification. Nucleic Acids Research . doi:10.1093/nar/gkx319

Emmanuel de los Santos, L. C. and Challis, Gregory L. (2017) clusterTools : proximity searches for functional elements to identify putative biosynthetic gene clusters. UNSPECIFIED. Cold Spring Harbor Labs Journals. (Submitted)

Awodi, U. R., Ronan, Jade L., Masschelein, J., Emmanuel de los Santos, L. C. and Challis, Gregory L. (2017) Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis. Chemical Science, 8 (1). pp. 411-415. doi:10.1039/C6SC02803A

2016

Zhou, Shanshan, Alkhalaf, Lona M., Emmanuel de los Santos, L. C. and Challis, Gregory L. (2016) Mechanistic insights into class B radical-S-adenosylmethionine methylases : ubiquitous tailoring enzymes in natural product biosynthesis. Current Opinion in Chemical Biology, 35 . pp. 73-79. doi:10.1016/j.cbpa.2016.08.021

Emmanuel de los Santos, L. C., Meyerowitz, Joseph T., Mayo, Stephen L. and Murray, Richard M. (2016) Engineering transcriptional regulator effector specificity using computational design and in vitrorapid prototyping : developing a vanillin sensor. ACS Synthetic Biology, 5 (4). pp. 287-295. doi:10.1021/acssynbio.5b00090

2015

Hsiao, Victoria, Emmanuel de los Santos, L. C., Whitaker, Weston R., Dueber, John E. and Murray, Richard M. (2015) Design and implementation of a biomolecular concentration tracker. ACS Synthetic Biology, 4 (2). pp. 150-161. doi:10.1021/sb500024b

2013

Emmanuel de los Santos, L. C., Hsiao, V., Whitaker, W. R., Dueber, J. E. and Murray, Richard M. (2013) Design and implementation of a biomolecular circuit for tracking protein concentration. In: American Control Conference 2013, Washington, DC, 17-19 Jun 2013. Published in: Proceedings of American Control Conference 2013 pp. 2290-2294.