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Jump to: ANR Physique-Chimie du Vivant | Action Medical Research (AMR) | Ara Parseghian Medical Research Foundation (APMRF) | Assocation pour la Recherche contre le Cancer | Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | Cancer Research Campaign (Great Britain) (CRC) | Cancer Research UK | Danish Council for Independent Research | Deutsche Forschungsgemeinschaft (DFG) | European Commission | Fifth Framework Programme (European Commission) (FP5) | Fondation de France | Fondation pour la recherche mΓ©dicale (FRM) | Great Britain. Dept. of Health (DoH) | Great Britain. Home Office | Irma T. Hirschl Trust | Leverhulme Trust (LT) | Ligue nationale contre le cancer (France) (LNCC) | Lundbeck Foundation | Max-Planck-Gesellschaft zur FΓΆrderung der Wissenschaften [Max Planck Society for the Advancement of Science] | Medical Research Council (Great Britain) (MRC) | National Institutes of Health | National Institutes of Health (U.S.) (NIH) | Novo Nordisk Foundation | Oxford Glycobiology Institute Endowment (OGIE) | Robert A. Welch Foundation Chair | United Kingdom Medical Research Council | United States. Defense Threat Reduction Agency (DTRA) | Wellcome Trust | Wellcome Trust (London, England) | Wellcome Trust Program
Number of items: 74.
ANR Physique-Chimie du Vivant
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
Action Medical Research (AMR)
Smith, Daniel C. , Sillence, Daniel J., FalguieΜres, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035 ISSN 1059-1524.
Ara Parseghian Medical Research Foundation (APMRF)
Smith, Daniel C. , Sillence, Daniel J., FalguieΜres, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035 ISSN 1059-1524.
Assocation pour la Recherche contre le Cancer
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Aletrari, Mina-Olga , McKibbin, Craig, Williams, Helen, Pawar, Vidya, Pietroni, Paola, Lord, Mike, Flitsch, Sabine L., Whitehead, Roger C., Swanton, Eileithyia, High, Stephen and Spooner, Robert A. (2011) Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways. PLoS One, Vol.6 (No.7). e22713. doi:10.1371/journal.pone.0022713 ISSN 1932-6203.
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, SchnΓΆder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743 ISSN 1939-4586.
Guetzoyan, Lucie J., Spooner, Robert A. , Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking. European Journal of Medicinal Chemistry, Vol.45 (No.1). pp. 275-283. doi:10.1016/j.ejmech.2009.10.007 ISSN 0223-5234.
Guetzoyan, Lucie J., Spooner, Robert A. , Boal, FrΓ©dΓ©ric, Stephens, David J., Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells. Molecular BioSystems, Vol.6 (No.10). pp. 2030-2038. doi:10.1039/c0mb00035c ISSN 1742-206X.
Marshall, Richard S., Jolliffe, Nicholas A., Ceriotti, Aldo, Snowden, Christopher J., Lord, Mike, Frigerio, Lorenzo and Roberts, L. M. (Lynne M.) (2009) The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells. Journal of Biological Chemistry, Vol.283 . pp. 15869-15877. doi:10.1074/jbc.M709316200 ISSN 0021-9258.
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi -mannosidase II locus. Journal of Biological Chemistry . doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Chamberlain, Kerry L., Marshall, Richard S., Jolliffe, Nicholas A., Frigerio, Lorenzo, Ceriotti, Aldo, Lord, Mike and Roberts, L. M. (Lynne M.) (2008) Ricin B chain targeted to the endoplasmic reticulum of tobacco protoplasts is degraded by a CDC48- and vacuole-independent mechanism. Journal of Biological Chemistry, Vol.283 (No.48). pp. 33276-33286. doi:10.1074/jbc.M805222200 ISSN 0021-9258.
Spooner, Robert A., Harte, Philip J. , Cook, Jonathan P., Pietroni, Paola, Rogon, Christian, HΓΆhfeld, JΓΆrg, Roberts, L. M. (Lynne M.) and Lord, Mike (2008) Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.45). pp. 17408-17413. doi:10.1073/pnas.0809013105 ISSN 0027-8424.
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, FrΓ©dΓ©ric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
Spooner, Robert A. , Smith, Daniel C., Easton, A. J. (Andrew J.), Roberts, L. M. (Lynne M.) and Lord, Mike (2006) Retrograde transport pathways utilised by viruses and protein toxins. Virology Journal, Vol.3 . p. 26. doi:10.1186/1743-422X-3-26 ISSN 1743-422X.
Smith, Daniel C. , Sillence, Daniel J., FalguieΜres, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035 ISSN 1059-1524.
Spooner, Robert A. , Watson, Peter, Marsden, Catherine J., Smith, Daniel C., Moore, Katherine A. H., Cook, Jonathan P., Lord, Mike and Roberts, L. M. (Lynne M.) (2004) Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum. Biochemical Journal, Vol.383 (No.2). pp. 285-293. doi:10.1042/BJ20040742 ISSN 0264-6021.
Cancer Research Campaign (Great Britain) (CRC)
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi -mannosidase II locus. Journal of Biological Chemistry . doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Cancer Research UK
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus. Journal of Biological Chemistry, Vol.284 (No.32). pp. 21684-21695. doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Danish Council for Independent Research
Pietroni, Paola, Vasisht, Nishi, Cook, Jonathan P., Roberts, David M., Lord, Mike, Hartmann-Petersen, Rasmus, Roberts, L. M. (Lynne M.) and Spooner, Robert A. (2013) The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain. Biochemical Journal, Volume 453 (Number 3). pp. 435-445. doi:10.1042/BJ20130133 ISSN 0264-6021.
Deutsche Forschungsgemeinschaft (DFG)
Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, SchnΓΆder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743 ISSN 1939-4586.
Spooner, Robert A., Harte, Philip J. , Cook, Jonathan P., Pietroni, Paola, Rogon, Christian, HΓΆhfeld, JΓΆrg, Roberts, L. M. (Lynne M.) and Lord, Mike (2008) Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.45). pp. 17408-17413. doi:10.1073/pnas.0809013105 ISSN 0027-8424.
Fuchs, Evelyn, Hass, Alexander K., Spooner, Robert A. , Yoshimura, Shin-ichiro , Lord, Mike and Barr, Francis A. (2007) Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. Journal of Cell Biology, Vol.177 (No.6). pp. 1133-1143. doi:10.1083/jcb.200612068 ISSN 0021-9525.
European Commission
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus. Journal of Biological Chemistry, Vol.284 (No.32). pp. 21684-21695. doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Fifth Framework Programme (European Commission) (FP5)
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi -mannosidase II locus. Journal of Biological Chemistry . doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Fondation de France
Smith, Daniel C. , Sillence, Daniel J., FalguieΜres, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035 ISSN 1059-1524.
Fondation pour la recherche mΓ©dicale (FRM)
Smith, Daniel C. , Sillence, Daniel J., FalguieΜres, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035 ISSN 1059-1524.
Great Britain. Dept. of Health (DoH)
Pawar, Vidya, De, Antara, Briggs, Laura, Omar, Mahmoud M., Sweeney, Sean T., Lord, Mike, Roberts, L. M. (Lynne M.), Spooner, Robert A. and Moffat, Kevin G. (2011) RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Journal of Biomolecular Screening, Vol.16 (No.4). pp. 436-442. doi:10.1177/1087057110397890 ISSN 1087-0571.
Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, SchnΓΆder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743 ISSN 1939-4586.
Great Britain. Home Office
Pawar, Vidya, De, Antara, Briggs, Laura, Omar, Mahmoud M., Sweeney, Sean T., Lord, Mike, Roberts, L. M. (Lynne M.), Spooner, Robert A. and Moffat, Kevin G. (2011) RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Journal of Biomolecular Screening, Vol.16 (No.4). pp. 436-442. doi:10.1177/1087057110397890 ISSN 1087-0571.
Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, SchnΓΆder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743 ISSN 1939-4586.
Irma T. Hirschl Trust
Redmann, V., Oresic, K., Tortorella, L. L., Cook, Jonathan P., Lord, Mike and Tortorella, D. (2011) Dislocation of ricin toxin A chains in human cells utilizes selective cellular factors. Journal of Biological Chemistry, Vol.286 (No.24). pp. 21231-21238. doi:10.1074/jbc.M111.234708 ISSN 0021-9258.
Leverhulme Trust (LT)
Marshall, Richard S., Jolliffe, Nicholas A., Ceriotti, Aldo, Snowden, Christopher J., Lord, Mike, Frigerio, Lorenzo and Roberts, L. M. (Lynne M.) (2009) The role of CDC48 in the retro-translocation of non-ubiquitinated toxin substrates in plant cells. Journal of Biological Chemistry, Vol.283 . pp. 15869-15877. doi:10.1074/jbc.M709316200 ISSN 0021-9258.
Ligue nationale contre le cancer (France) (LNCC)
Smith, Daniel C. , Sillence, Daniel J., FalguieΜres, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035 ISSN 1059-1524.
Lundbeck Foundation
Pietroni, Paola, Vasisht, Nishi, Cook, Jonathan P., Roberts, David M., Lord, Mike, Hartmann-Petersen, Rasmus, Roberts, L. M. (Lynne M.) and Spooner, Robert A. (2013) The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain. Biochemical Journal, Volume 453 (Number 3). pp. 435-445. doi:10.1042/BJ20130133 ISSN 0264-6021.
Max-Planck-Gesellschaft zur FΓΆrderung der Wissenschaften [Max Planck Society for the Advancement of Science]
Fuchs, Evelyn, Hass, Alexander K., Spooner, Robert A. , Yoshimura, Shin-ichiro , Lord, Mike and Barr, Francis A. (2007) Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. Journal of Cell Biology, Vol.177 (No.6). pp. 1133-1143. doi:10.1083/jcb.200612068 ISSN 0021-9525.
Medical Research Council (Great Britain) (MRC)
Pawar, Vidya, De, Antara, Briggs, Laura, Omar, Mahmoud M., Sweeney, Sean T., Lord, Mike, Roberts, L. M. (Lynne M.), Spooner, Robert A. and Moffat, Kevin G. (2011) RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Journal of Biomolecular Screening, Vol.16 (No.4). pp. 436-442. doi:10.1177/1087057110397890 ISSN 1087-0571.
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi -mannosidase II locus. Journal of Biological Chemistry . doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, FrΓ©dΓ©ric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
National Institutes of Health
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus. Journal of Biological Chemistry, Vol.284 (No.32). pp. 21684-21695. doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Mayerhofer, Peter U., Cook, Jonathan P., Wahlman, Judit, Pinheiro, Teresa J. T., Moore, Katherine A. H., Lord, Mike, Johnson, Arthur E. and Roberts, L. M. (Lynne M.) (2009) Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 degrees C. Journal of Biological Chemistry, Vol.284 (No.15). pp. 10232-10242. doi:10.1074/jbc.M808387200 ISSN 0021-9258.
National Institutes of Health (U.S.) (NIH)
Spooner, Robert A. and Lord, Mike (2012) How ricin and shiga toxin reach the cytosol of target cells : retrotranslocation from the endoplasmic reticulum. Current Topics in Microbiology and Immunology, Vol.357 . pp. 19-40. doi:1007/82_2011_154 ISSN 0070-217X.
Aletrari, Mina-Olga , McKibbin, Craig, Williams, Helen, Pawar, Vidya, Pietroni, Paola, Lord, Mike, Flitsch, Sabine L., Whitehead, Roger C., Swanton, Eileithyia, High, Stephen and Spooner, Robert A. (2011) Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways. PLoS One, Vol.6 (No.7). e22713. doi:10.1371/journal.pone.0022713 ISSN 1932-6203.
Redmann, V., Oresic, K., Tortorella, L. L., Cook, Jonathan P., Lord, Mike and Tortorella, D. (2011) Dislocation of ricin toxin A chains in human cells utilizes selective cellular factors. Journal of Biological Chemistry, Vol.286 (No.24). pp. 21231-21238. doi:10.1074/jbc.M111.234708 ISSN 0021-9258.
Pawar, Vidya, De, Antara, Briggs, Laura, Omar, Mahmoud M., Sweeney, Sean T., Lord, Mike, Roberts, L. M. (Lynne M.), Spooner, Robert A. and Moffat, Kevin G. (2011) RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Journal of Biomolecular Screening, Vol.16 (No.4). pp. 436-442. doi:10.1177/1087057110397890 ISSN 1087-0571.
Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, SchnΓΆder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743 ISSN 1939-4586.
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi -mannosidase II locus. Journal of Biological Chemistry . doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Spooner, Robert A., Harte, Philip J. , Cook, Jonathan P., Pietroni, Paola, Rogon, Christian, HΓΆhfeld, JΓΆrg, Roberts, L. M. (Lynne M.) and Lord, Mike (2008) Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.45). pp. 17408-17413. doi:10.1073/pnas.0809013105 ISSN 0027-8424.
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, FrΓ©dΓ©ric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
Fuchs, Evelyn, Hass, Alexander K., Spooner, Robert A. , Yoshimura, Shin-ichiro , Lord, Mike and Barr, Francis A. (2007) Specific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathways. Journal of Cell Biology, Vol.177 (No.6). pp. 1133-1143. doi:10.1083/jcb.200612068 ISSN 0021-9525.
Spooner, Robert A. , Smith, Daniel C., Easton, A. J. (Andrew J.), Roberts, L. M. (Lynne M.) and Lord, Mike (2006) Retrograde transport pathways utilised by viruses and protein toxins. Virology Journal, Vol.3 . p. 26. doi:10.1186/1743-422X-3-26 ISSN 1743-422X.
Novo Nordisk Foundation
Pietroni, Paola, Vasisht, Nishi, Cook, Jonathan P., Roberts, David M., Lord, Mike, Hartmann-Petersen, Rasmus, Roberts, L. M. (Lynne M.) and Spooner, Robert A. (2013) The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain. Biochemical Journal, Volume 453 (Number 3). pp. 435-445. doi:10.1042/BJ20130133 ISSN 0264-6021.
Oxford Glycobiology Institute Endowment (OGIE)
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi -mannosidase II locus. Journal of Biological Chemistry . doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Robert A. Welch Foundation Chair
Mayerhofer, Peter U., Cook, Jonathan P., Wahlman, Judit, Pinheiro, Teresa J. T., Moore, Katherine A. H., Lord, Mike, Johnson, Arthur E. and Roberts, L. M. (Lynne M.) (2009) Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 degrees C. Journal of Biological Chemistry, Vol.284 (No.15). pp. 10232-10242. doi:10.1074/jbc.M808387200 ISSN 0021-9258.
United Kingdom Medical Research Council
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus. Journal of Biological Chemistry, Vol.284 (No.32). pp. 21684-21695. doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
United States. Defense Threat Reduction Agency (DTRA)
Redmann, V., Oresic, K., Tortorella, L. L., Cook, Jonathan P., Lord, Mike and Tortorella, D. (2011) Dislocation of ricin toxin A chains in human cells utilizes selective cellular factors. Journal of Biological Chemistry, Vol.286 (No.24). pp. 21231-21238. doi:10.1074/jbc.M111.234708 ISSN 0021-9258.
Wellcome Trust
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi alpha-mannosidase II locus. Journal of Biological Chemistry, Vol.284 (No.32). pp. 21684-21695. doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Wellcome Trust (London, England)
Spooner, Robert A. and Lord, Mike (2015) Ricin trafficking in cells. Toxins, Volume 7 (Number 1). pp. 49-65. doi:10.3390/toxins7010049 ISSN 2072-6651.
Pietroni, Paola, Vasisht, Nishi, Cook, Jonathan P., Roberts, David M., Lord, Mike, Hartmann-Petersen, Rasmus, Roberts, L. M. (Lynne M.) and Spooner, Robert A. (2013) The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain. Biochemical Journal, Volume 453 (Number 3). pp. 435-445. doi:10.1042/BJ20130133 ISSN 0264-6021.
Li, Shuyu, Spooner, Robert A. , Hampton, Randolph Y., Lord, Mike and Roberts, L. M. (Lynne M.) (2012) Cytosolic entry of Shiga-like toxin A chain from the yeast endoplasmic reticulum requires catalytically active Hrd1p. PLoS ONE, Vol.7 (No.7). e41119. doi:10.1371/journal.pone.0041119 ISSN 1932-6203.
Spooner, Robert A. and Lord, Mike (2012) How ricin and shiga toxin reach the cytosol of target cells : retrotranslocation from the endoplasmic reticulum. Current Topics in Microbiology and Immunology, Vol.357 . pp. 19-40. doi:1007/82_2011_154 ISSN 0070-217X.
Aletrari, Mina-Olga , McKibbin, Craig, Williams, Helen, Pawar, Vidya, Pietroni, Paola, Lord, Mike, Flitsch, Sabine L., Whitehead, Roger C., Swanton, Eileithyia, High, Stephen and Spooner, Robert A. (2011) Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways. PLoS One, Vol.6 (No.7). e22713. doi:10.1371/journal.pone.0022713 ISSN 1932-6203.
Pawar, Vidya, De, Antara, Briggs, Laura, Omar, Mahmoud M., Sweeney, Sean T., Lord, Mike, Roberts, L. M. (Lynne M.), Spooner, Robert A. and Moffat, Kevin G. (2011) RNAi screening of Drosophila (Sophophora) melanogaster S2 cells for ricin sensitivity and resistance. Journal of Biomolecular Screening, Vol.16 (No.4). pp. 436-442. doi:10.1177/1087057110397890 ISSN 1087-0571.
Li, Shuyu, Spooner, Robert A. , Allen, Stuart C. H., Guise, Christopher P., Ladds, Graham, SchnΓΆder, Tina, Schmitt, Manfred J., Lord, Mike and Roberts, L. M. (Lynne M.) (2010) Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum. Molecular Biology of the Cell, Vol.21 (No.15). pp. 2543-2554. doi:10.1091/mbc.E09-08-0743 ISSN 1939-4586.
Guetzoyan, Lucie J., Spooner, Robert A. , Boal, FrΓ©dΓ©ric, Stephens, David J., Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells. Molecular BioSystems, Vol.6 (No.10). pp. 2030-2038. doi:10.1039/c0mb00035c ISSN 1742-206X.
Crispin, Max, Chang, Veronica T., Harvey, David J., Dwek, Raymond A., Evans, Edward J., Stuart, David I., Jones, E. Yvonne, Lord, Mike, Spooner, Robert A. and Davis, Simon J. (2009) A human embryonic kidney 293T cell line mutated at the Golgi -mannosidase II locus. Journal of Biological Chemistry . doi:10.1074/jbc.M109.006254 ISSN 0021-9258.
Chamberlain, Kerry L., Marshall, Richard S., Jolliffe, Nicholas A., Frigerio, Lorenzo, Ceriotti, Aldo, Lord, Mike and Roberts, L. M. (Lynne M.) (2008) Ricin B chain targeted to the endoplasmic reticulum of tobacco protoplasts is degraded by a CDC48- and vacuole-independent mechanism. Journal of Biological Chemistry, Vol.283 (No.48). pp. 33276-33286. doi:10.1074/jbc.M805222200 ISSN 0021-9258.
Spooner, Robert A., Harte, Philip J. , Cook, Jonathan P., Pietroni, Paola, Rogon, Christian, HΓΆhfeld, JΓΆrg, Roberts, L. M. (Lynne M.) and Lord, Mike (2008) Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.45). pp. 17408-17413. doi:10.1073/pnas.0809013105 ISSN 0027-8424.
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, FrΓ©dΓ©ric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
Spooner, Robert A. , Smith, Daniel C., Easton, A. J. (Andrew J.), Roberts, L. M. (Lynne M.) and Lord, Mike (2006) Retrograde transport pathways utilised by viruses and protein toxins. Virology Journal, Vol.3 . p. 26. doi:10.1186/1743-422X-3-26 ISSN 1743-422X.
Smith, Daniel C. , Sillence, Daniel J., FalguieΜres, Thomas, Jarvis, Rosemary M., Johannes, Ludger, Lord, Mike, Platt, Frances M. and Roberts, L. M. (Lynne M.) (2006) The association of shiga-like toxin with detergent-resistant membranes is modulated by glucosylceramide and is an essential requirement in the endoplasmic reticulum for a cytotoxic effect. Molecular Biology of the Cell, Vol.17 (No.3). pp. 1375-1387. doi:10.1091/mbc.E05-11-1035 ISSN 1059-1524.
Spooner, Robert A. , Watson, Peter, Marsden, Catherine J., Smith, Daniel C., Moore, Katherine A. H., Cook, Jonathan P., Lord, Mike and Roberts, L. M. (Lynne M.) (2004) Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum. Biochemical Journal, Vol.383 (No.2). pp. 285-293. doi:10.1042/BJ20040742 ISSN 0264-6021.
Wellcome Trust Program
Mayerhofer, Peter U., Cook, Jonathan P., Wahlman, Judit, Pinheiro, Teresa J. T., Moore, Katherine A. H., Lord, Mike, Johnson, Arthur E. and Roberts, L. M. (Lynne M.) (2009) Ricin A chain insertion into endoplasmic reticulum membranes is triggered by a temperature increase to 37 degrees C. Journal of Biological Chemistry, Vol.284 (No.15). pp. 10232-10242. doi:10.1074/jbc.M808387200 ISSN 0021-9258.
This list was generated on Thu Apr 25 00:50:36 2024 BST.