2014

Liu, Zhe , Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. doi:10.1002/anie.201311161

2013

Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183

Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374

Pizarro, Ana M. and Sadler, P. J. (2013) Cancer chemistry : designing new drugs for cancer treatment. In: Pelengaris , Stella and Khan, Mike, (eds.) The molecular biology of cancer : a bridge from bench to bedside, 2nd Edition. Hoboken, NJ: Wiley-Blackwell. ISBN 9781118022870

2012

Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9

Noffke, Anna Louise, Habtemariam, Abraha, Pizarro, Ana M. and Sadler, P. J. (2012) Designing organometallic compounds for catalysis and therapy. Chemical Communications, Vol.48 (No.43). pp. 5219-5246. doi:10.1039/c2cc30678f

Romero-Canelón, Isolda, Pizarro, Ana M., Habtemariam, Abraha and Sadler, P. J. (2012) Contrasting cellular uptake pathways for chlorido and iodido iminopyridine ruthenium arene anticancer complexes. Metallomics, Volume 4 (Number 12). pp. 1271-1279. doi:10.1039/c2mt20189e

Betanzos-Lara, Soledad, Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Qamar, Bushra and Sadler, P. J. (2012) Organometallic ruthenium and iridium transfer-hydrogenation catalysts using coenzyme NADH as a cofactor. Angewandte Chemie International Edition, Vol.51 (No.16). pp. 3897-3900. doi:10.1002/anie.201108175

Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y

Fu, Y. (Ying), Romero, Maria, Habtemariam, Abraha, Snowden, Michael E., Song, Lijiang, Clarkson, Guy J., Qamar, Bushra, Pizarro, Ana M., Unwin, Patrick R. and Sadler, P. J. (2012) The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexes. Chemical Science, Vol.3 (No.8). pp. 2485-2494. doi:10.1039/c2sc20220d

2011

Ronconi, Luca, Pizarro, Ana M., McQuitty, Ruth J. and Sadler, P. J. (2011) Insights into the acid-base properties of PtIV-diazidodiam(m)inedihyroxido complexes from multinuclear NMR spectroscopy. Chemistry - A European Journal, Volume 17 (Number 43). pp. 12051-12058. doi:10.1002/chem.201002792

Fu, Ying, Shnyder, Steve D., Habtemariam, Abraha, Clarkson, Guy J., Cooper, Patricia A., Loadman, Paul M., Pizarro, Ana M. and Sadler, P. J. (2011) Organometallic osmium arene anticancer complexes. In: 242nd National Meeting of the American-Chemical-Society (ACS), Denver, CO, 28 Aug - 1 Sep 2011. Published in: American Chemical Society. Abstracts of Papers (at the National Meeting), Vol.242 17-BIOL. ISSN 0065-7727.

Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468

Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j

Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932

Li, Huilin, Lin, Tzu-Yung, Van Orden, Steve L., Zhao, Yao, (Researcher in chemistry), Barrow, Mark P., Pizarro, Ana M., Qi, Yulin, Sadler, P. J. and O’Connor, Peter B. (2011) Use of top-down and bottom-up fourier transform ion cyclotron resonance mass spectrometry for mapping calmodulin sites modified by platinum anticancer drugs. Analytical Chemistry, Vol.83 (No.24). pp. 9507-9515. doi:10.1021/ac202267g

2010

Salassa, Luca, Ruiu, Tiziana, Garino, Claudio, Pizarro, Ana M., Bardelli, Fabrizio, Gianolio, Diego, Westendorf, Aron, Bednarski, Patrick J., Lamberti, Carlo, Gobetto, Roberto and Sadler, P. J. (2010) EXAFS, DFT, light-induced nucleobase binding, and cytotoxicity of the photoactive complex cis-[Ru(bpy)2(CO)Cl]+. Organometallics, Vol.29 (No.4). pp. 6703-6710. doi:10.1021/om100734y

Cubo, Leticia, Pizarro, Ana M., Quiroga, Adoracion G., Salassa, Luca, Navarro-Ranninger, Carmen and Sadler, P. J. (2010) Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides. Journal of Inorganic Biochemistry, Vol.104 (No.9). pp. 909-918. doi:10.1016/j.jinorgbio.2010.04.009

Pizarro, Ana M., Melchart, Michael, Habtemariam, Abraha, Salassa, Luca, Fabbiani, Francesca P. A., Parsons, S. (Simon) and Sadler, P. J. (2010) Controlling the reactivity of ruthenium(II) arene complexes by tether ring-opening. Inorganic Chemistry, Vol.49 (No.7). pp. 3310-3319. doi:10.1021/ic902243q

Ruiu, Tiziana, Garino, Claudio, Salassa, Luca, Pizarro, Ana M., Nervi, Carlo, Gobetto, Roberto and Sadler, P. J. (2010) Spectroscopic and computational study of ligand photodissociation from [Ru(dipyrido[3,2-a:2',3'-c]phenazine)(4-aminopyridine)(4)](2+). European Journal of Inorganic Chemistry, Vol.2010 (No.8). pp. 1186-1195. doi:10.1002/ejic.200900990

Rijt, Sabine H. van, Mukherjee, Arindam, Pizarro, Ana M. and Sadler, P. J. (2010) Cytotoxicity, hydrophobicity, uptake, and distribution of osmium(II) anticancer complexes in ovarian cancer cells. Journal of Medicinal Chemistry, Vol.53 (No.2). pp. 840-849. doi:10.1021/jm901556u

Pizarro, Ana M., Habtemariam, Abraha and Sadler, P. J. (2010) Activation mechanisms for organometallic anticancer complexes. In: Jaouen, Gérard and Metzler-Nolte, Nils, (eds.) Medicinal organometallic chemistry. Topics in Organometallic Chemistry, Vol.32 . Berlin ; New York: Springer-Verlag, pp. 21-56. ISBN 9783642131844

2009

Pizarro, Ana M. and Sadler, P. J. (2009) Unusual DNA binding modes for metal anticancer complexes. Biochimie, Vol.91 (No.10). pp. 1198-1211. doi:10.1016/j.biochi.2009.03.017

Pizarro, Ana M. and Sadler, P. J. (2009) Metal ion–nucleic acid interactions in disease and medicine. In: Hud, Nicholas V. (Nicholas Vincent), (ed.) Nucleic Acid-Metal Ion Interactions. RSC biomolecular sciences . Cambridge, UK: Royal Society of Chemistry, pp. 350-416. ISBN 9780854041954

2007

Mackay, Fiona S., Woods, Julie A., Heringova, Pavia, Kasparkova, Jana, Pizarro, Ana M., Moggach, Stephen A., Parsons, Simon, Brabec, V. (Viktor) and Sadler, P. J. (2007) A potent cytotoxic photoactivated platinum complex. Proceedings of the National Academy of Sciences of the United States of America, Vol.104 (No.52). pp. 20743-20748. doi:10.1073/pnas.0707742105