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Number of items: 285.
Woolley, Jack Matthew, Peters, Jack S., Turner, Matthew A. P., Clarkson, Guy J., Horbury, Michael D. and Stavros, Vasilios G. (2019) The role of symmetric functionalisation on photoisomerisation of a UV commercial chemical. Physical Chemistry Chemical Physics, 21 (26). pp. 14350-14356. doi:10.1039/C8CP06536E ISSN 1463-9076.
ANR Physique-Chimie du Vivant
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
Advantage West Midlands
Crosby, Sarah H., Clarkson, Guy J., Deeth, Robert J. and Rourke, Jonathan (2010) Platinum(IV) DMSO complexes : synthesis, isomerization, and agostic intermediates. Organometallics, Vol.29 (No.8). pp. 1966-1976. doi:10.1021/om901087m ISSN 0276-7333.
Advantage West Midlands (AWM)
Shaw, Paul Anthony, Clarkson, Guy J. and Rourke, Jonathan (2017) Oxidation of an o -tolyl phosphine complex of platinum : C-H activation and transcyclometallation. Journal of Organometallic Chemistry, 851 . pp. 115-121. doi:10.1016/j.jorganchem.2017.09.026 ISSN 0022-328X.
Brown, Thomas Joseph, Cumbes, Madeleine, Diorazio, Louis J., Clarkson, Guy J. and Wills, Martin (2017) Use of (Cyclopentadienone)iron tricarbonyl complexes for C–N bond formation reactions between amines and alcohols. The Journal of Organic Chemistry, 82 (19). pp. 10489-10503. doi:10.1021/acs.joc.7b01990 ISSN 0022-3263.
Del Grosso, Alessandro, Galanopoulos, Lavrentis-Dimitrios, Chiu, Cookson K. C., Clarkson, Guy J., O'Connor, Peter B. and Wills, Martin (2017) Strained alkynes derived from 2,2′-dihydroxy-1,1′-biaryls ; synthesis and copper-free cycloaddition with azides. Organic & Biomolecular Chemistry, 15 (21). 4517-4521 . doi:10.1039/C7OB00991G ISSN 1477-0520.
Shaw, Paul Anthony, Clarkson, Guy J. and Rourke, Jonathan (2017) Reversible C–C bond formation at a triply cyclometallated platinum(iv) centre. Chemical Science . doi:10.1039/C7SC01361B ISSN 2041-6520.
Shaw, Paul Anthony, Phillips, Jessica M., Clarkson, Guy J. and Rourke, Jonathan (2016) Trapping five-coordinate platinum(IV) intermediates. Dalton Transactions, 45 (28). 11397-11406 . doi:10.1039/c6dt02088g ISSN 1477-9226.
Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition, 55 (31). pp. 8909-8912. doi:10.1002/anie.201602995 ISSN 1433-7851.
Shipman, Michael, Beadle, Jonathan D., Powell, Nicola Helen, Raubo, Piotr and Clarkson, Guy J. (2015) Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework. Synlett, 27 (1). pp. 169-172. doi:10.1055/s-0035-1560593 ISSN 0936-5214.
Shaw, Paul Anthony, Phillips, Jessica M., Newman, Christopher P., Clarkson, Guy J. and Rourke, Jonathan (2015) Intramolecular transcyclometallation : the exchange of an aryl–Pt bond for an alkyl–Pt bond via an agostic intermediate. Chemical Communications, Volume 51 (Number 39). pp. 8365-8368. doi:10.1039/c5cc02355f ISSN 1359-7345.
Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2015) Tethered Ru(II) catalysts containing a Ru–I bond. Journal of Organometallic Chemistry, 776 . pp. 157-162. doi:10.1016/j.jorganchem.2014.10.033 ISSN 0022-328X.
Liu, Zhe , Romero-Canelón, Isolda, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2014) Potent half-sandwich iridium(III) anticancer complexes containing C∧N-Chelated and pyridine ligands. Organometallics, 33 (19). pp. 5324-5333. doi:10.1021/om500644f ISSN 0276-7333.
Rochford, Luke A., Keeble, Dean Samuel, Holmes, O. J., Clarkson, Guy J. and Jones, T. S. (Tim S.) (2014) Controlling templating effects at the organic/inorganic interface using (111) oriented copper iodide. Journal of Materials Chemistry C, Volume 2 (Number 30). pp. 6056-6060. doi:10.1039/c4tc00759j ISSN 2050-7526.
Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183 ISSN 0947-6539.
Soni, Rina, Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2013) Direct formation of tethered Ru(II) catalysts using arene exchange. Organic Letters, 15 (19). pp. 5110-5113. doi:10.1021/ol4024979 ISSN 1523-7060.
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Darwish, Moftah O., Wallace, Alistair, Clarkson, Guy J. and Wills, Martin (2013) Use of tridentate TsDPEN/pyridine ligands in ruthenium-catalysed asymmetric reduction of ketones. Tetrahedron Letters, 54 (32). pp. 4250-4253. doi:10.1016/j.tetlet.2013.05.141 ISSN 0040-4039.
Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9 ISSN 0949-8257.
Crosby, Sarah H., Thomas, Helen R., Clarkson, Guy J. and Rourke, Jonathan (2012) Concerted reductive coupling of an alkyl chloride at Pt(IV). Chemical Communications, Vol.48 (No.46). pp. 5775-5777. doi:10.1039/c2cc31572f ISSN 1359-7345.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Bisset, Alexander A., Shiibashi, Akira, Desmond, Jasmine L., Dishington, Allan, Jones, Teyrnon, Clarkson, Guy J., Ikariya, Takao and Wills, Martin (2012) Synthesis and asymmetric hydrogenation of (3E)-1-benzyl-3-[(2-oxopyridin-1(2H)-yl)methylidene]piperidine-2,6-dione. Chemical Communications, 48 (98). pp. 11978-11980. doi:10.1039/c2cc36807b ISSN 1359-7345.
Fu, Y. (Ying), Romero, Maria, Habtemariam, Abraha, Snowden, Michael E., Song, Lijiang, Clarkson, Guy J., Qamar, Bushra, Pizarro, Ana M., Unwin, Patrick R. and Sadler, P. J. (2012) The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexes. Chemical Science, Vol.3 (No.8). pp. 2485-2494. doi:10.1039/c2sc20220d ISSN 2041-6520.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468 ISSN 0276-7333.
Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. doi:10.1002/ejic.201100250 ISSN 1434-1948.
Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j ISSN 0020-1669.
Brown, M. J. (Michael J.), Clarkson, Guy J., Inglis, Graham G. and Shipman, Michael (2011) Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis. Organic Letters, Volume 13 (Number 7). pp. 1686-1689. doi:10.1021/ol200193n ISSN 1523-7060.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Crosby, Sarah H., Deeth, Robert J., Clarkson, Guy J. and Rourke, Jonathan (2011) Platinum(iv) centres with agostic interactions from either sp2 or sp3 C–H bonds. Dalton Transactions, Vol.40 (No.6). pp. 1227-1229. doi:10.1039/c0dt01428a ISSN 1477-9226.
Fu, Y. (Ying), Habtemariam, Abraha, Basri, Aida M. B. H., Braddick, Darren, Clarkson, Guy J. and Sadler, P. J. (2011) Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity. Dalton Transactions (No.40). pp. 10553-10562. doi:10.1039/c1dt10937e ISSN 1477-9226.
Fu, Y. (Ying), Habtemariam, Abraha, Pizarro, Ana M., Rijt, Sabine H. van, Healey, David J., Cooper, Patricia A., Shnyder, Steven D., Clarkson, Guy J. and Sadler, P. J. (2010) Organometallic osmium arene complexes with potent cancer cell cytotoxicity. Journal of Medicinal Chemistry, Vol.53 (No.22). pp. 8192-8196. doi:10.1021/jm100560f ISSN 0022-2623.
Gosiewska, Silvia, Soni, Rina, Clarkson, Guy J. and Wills, Martin (2010) Synthesis and use of a stable aminal derived from TsDPEN in asymmetric organocatalysis. Tetrahedron Letters, Vol.51 (No.32). pp. 4214-4217. doi:10.1016/j.tetlet.2010.06.017 ISSN 0040-4039.
Rijt, Sabine H. van, Hebden, Andrew J., Amaresekera, Thakshila, Deeth, Robert J., Clarkson, Guy J., Parsons, S. (Simon), McGowan, Patrick C. and Sadler, P. J. (2009) Amide linkage isomerism as an activity switch for organometallic osmium and ruthenium anticancer complexes. Journal of Medicinal Chemistry, Vol.52 (No.23). pp. 7753-7764. doi:10.1021/jm900731j ISSN 0022-2623.
Advantage West Midlands (AWM)
Johnson, Tarn C., Clarkson, Guy J. and Wills, Martin (2011) (Cyclopentadienone)iron shvo complexes : synthesis and applications to hydrogen transfer reactions. Organometallics, 30 (7). pp. 1859-1868. doi:10.1021/om101101r ISSN 0276-7333.
Advantage West Midlands (AWM) Advanced Materials Project
Morris, David J., Clarkson, Guy J. and Wills, Martin (2009) Insights into hydrogen generation from formic acid using ruthenium complexes. Organometallics, Vol.28 (No.14). pp. 4133-4140. doi:10.1021/om900099u ISSN 0276-7333.
Advantage West Midlands (part funded by the European Regional Development Fund)
Crosby, Sarah H., Clarkson, Guy J. and Rourke, Jonathan (2009) A delicate balance between sp(2) and sp(3) C-H bond activation : a Pt(II) complex with a dual agostic interaction. Journal of the American Chemical Society, Vol.131 (No.40). pp. 14142-14143. doi:10.1021/ja905046n ISSN 0002-7863.
Akademie věd České republiky [Academy of Sciences of the Czech Republic]
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Assocation pour la Recherche contre le Cancer
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
AstraZeneca (Firm)
Bisset, Alexander A., Dishington, Allan, Jones, Teyrnon C., Clarkson, Guy J. and Wills, Martin (2019) Data for Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines. [Dataset]
Brown, Thomas Joseph, Cumbes, Madeleine, Diorazio, Louis J., Clarkson, Guy J. and Wills, Martin (2017) Use of (Cyclopentadienone)iron tricarbonyl complexes for C–N bond formation reactions between amines and alcohols. The Journal of Organic Chemistry, 82 (19). pp. 10489-10503. doi:10.1021/acs.joc.7b01990 ISSN 0022-3263.
Shipman, Michael, Beadle, Jonathan D., Powell, Nicola Helen, Raubo, Piotr and Clarkson, Guy J. (2015) Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework. Synlett, 27 (1). pp. 169-172. doi:10.1055/s-0035-1560593 ISSN 0936-5214.
Bisset, Alexander A., Dishington, Allan, Jones, Teyrnon C., Clarkson, Guy J. and Wills, Martin (2014) Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines. Tetrahedron, 70 (40). pp. 7207-7220. doi:10.1016/j.tet.2014.06.046 ISSN 0040-4020 .
Bisset, Alexander A., Shiibashi, Akira, Desmond, Jasmine L., Dishington, Allan, Jones, Teyrnon, Clarkson, Guy J., Ikariya, Takao and Wills, Martin (2012) Synthesis and asymmetric hydrogenation of (3E)-1-benzyl-3-[(2-oxopyridin-1(2H)-yl)methylidene]piperidine-2,6-dione. Chemical Communications, 48 (98). pp. 11978-11980. doi:10.1039/c2cc36807b ISSN 1359-7345.
Soni, Rina, Cheung, Fung Kei, Clarkson, Guy J., Martins, Jose E. D., Graham, Mark A. and Wills, Martin (2011) The importance of the N–H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ketones and imines. Organic & Biomolecular Chemistry, 9 (9). pp. 3290-3294. doi:10.1039/c1ob05208j ISSN 1477-0520.
Cheung, Fung Kei, Clarke, Adam J., Clarkson, Guy J., Fox, David J., Graham, Mark A., Lin, Changxue, Crivillé, Adriana Lorente and Wills, Martin (2010) Kinetic and structural studies on 'tethered' Ru(II) arene ketone reduction catalysts. Dalton Transactions, Vol.39 (No.5). pp. 1395-1402. doi:10.1039/b915932k ISSN 1477-9226.
Banco de Santander
Breeze, Matthew, Chamberlain, Thomas W., Clarkson, Guy J., de Camargo, Raíssa Pires, Wu, Yue, Millange, Franck, Serra, Osvaldo A., O'Hare, Dermot, de Lima, Juliana Fonseca and Walton, Richard I. (2017) Structural variety in ytterbium dicarboxylate frameworks and in situ study diffraction of their solvothermal crystallisation. CrystEngCommun, 19 (17). pp. 2424-2433. ISSN 1466-8033.
Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition, 55 (31). pp. 8909-8912. doi:10.1002/anie.201602995 ISSN 1433-7851.
Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G. and Sadler, P. J. (2016) Combatting AMR : photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity. Chemical Science, 8 (1). pp. 395-404. doi:10.1039/C6SC03028A ISSN 2041-6520.
Liu, Zhe , Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. doi:10.1002/anie.201311161 ISSN 1433-7851.
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
Guetzoyan, Lucie J., Spooner, Robert A. , Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking. European Journal of Medicinal Chemistry, Vol.45 (No.1). pp. 275-283. doi:10.1016/j.ejmech.2009.10.007 ISSN 0223-5234.
Guetzoyan, Lucie J., Spooner, Robert A. , Boal, Frédéric, Stephens, David J., Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells. Molecular BioSystems, Vol.6 (No.10). pp. 2030-2038. doi:10.1039/c0mb00035c ISSN 1742-206X.
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, Frédéric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
Birmingham Science City
Brown, Thomas Joseph, Cumbes, Madeleine, Diorazio, Louis J., Clarkson, Guy J. and Wills, Martin (2017) Use of (Cyclopentadienone)iron tricarbonyl complexes for C–N bond formation reactions between amines and alcohols. The Journal of Organic Chemistry, 82 (19). pp. 10489-10503. doi:10.1021/acs.joc.7b01990 ISSN 0022-3263.
Del Grosso, Alessandro, Galanopoulos, Lavrentis-Dimitrios, Chiu, Cookson K. C., Clarkson, Guy J., O'Connor, Peter B. and Wills, Martin (2017) Strained alkynes derived from 2,2′-dihydroxy-1,1′-biaryls ; synthesis and copper-free cycloaddition with azides. Organic & Biomolecular Chemistry, 15 (21). 4517-4521 . doi:10.1039/C7OB00991G ISSN 1477-0520.
Hsueh, Nathanael, Clarkson, Guy J. and Shipman, Michael (2016) Functionalization of alkenes through telescoped continuous flow aziridination processes. Organic Letters, 18 (9). pp. 4908-4911. doi:10.1021/acs.orglett.6b02349 ISSN 1523-7060.
Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition, 55 (31). pp. 8909-8912. doi:10.1002/anie.201602995 ISSN 1433-7851.
Shipman, Michael, Beadle, Jonathan D., Powell, Nicola Helen, Raubo, Piotr and Clarkson, Guy J. (2015) Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework. Synlett, 27 (1). pp. 169-172. doi:10.1055/s-0035-1560593 ISSN 0936-5214.
Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2015) Tethered Ru(II) catalysts containing a Ru–I bond. Journal of Organometallic Chemistry, 776 . pp. 157-162. doi:10.1016/j.jorganchem.2014.10.033 ISSN 0022-328X.
Liu, Zhe , Romero-Canelón, Isolda, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2014) Potent half-sandwich iridium(III) anticancer complexes containing C∧N-Chelated and pyridine ligands. Organometallics, 33 (19). pp. 5324-5333. doi:10.1021/om500644f ISSN 0276-7333.
Soni, Rina, Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2013) Direct formation of tethered Ru(II) catalysts using arene exchange. Organic Letters, 15 (19). pp. 5110-5113. doi:10.1021/ol4024979 ISSN 1523-7060.
Darwish, Moftah O., Wallace, Alistair, Clarkson, Guy J. and Wills, Martin (2013) Use of tridentate TsDPEN/pyridine ligands in ruthenium-catalysed asymmetric reduction of ketones. Tetrahedron Letters, 54 (32). pp. 4250-4253. doi:10.1016/j.tetlet.2013.05.141 ISSN 0040-4039.
Bisset, Alexander A., Shiibashi, Akira, Desmond, Jasmine L., Dishington, Allan, Jones, Teyrnon, Clarkson, Guy J., Ikariya, Takao and Wills, Martin (2012) Synthesis and asymmetric hydrogenation of (3E)-1-benzyl-3-[(2-oxopyridin-1(2H)-yl)methylidene]piperidine-2,6-dione. Chemical Communications, 48 (98). pp. 11978-11980. doi:10.1039/c2cc36807b ISSN 1359-7345.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468 ISSN 0276-7333.
Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j ISSN 0020-1669.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Fu, Y. (Ying), Habtemariam, Abraha, Pizarro, Ana M., Rijt, Sabine H. van, Healey, David J., Cooper, Patricia A., Shnyder, Steven D., Clarkson, Guy J. and Sadler, P. J. (2010) Organometallic osmium arene complexes with potent cancer cell cytotoxicity. Journal of Medicinal Chemistry, Vol.53 (No.22). pp. 8192-8196. doi:10.1021/jm100560f ISSN 0022-2623.
Gosiewska, Silvia, Soni, Rina, Clarkson, Guy J. and Wills, Martin (2010) Synthesis and use of a stable aminal derived from TsDPEN in asymmetric organocatalysis. Tetrahedron Letters, Vol.51 (No.32). pp. 4214-4217. doi:10.1016/j.tetlet.2010.06.017 ISSN 0040-4039.
British Council
Cheung, Fung Kei, Clarke, Adam J., Clarkson, Guy J., Fox, David J., Graham, Mark A., Lin, Changxue, Crivillé, Adriana Lorente and Wills, Martin (2010) Kinetic and structural studies on 'tethered' Ru(II) arene ketone reduction catalysts. Dalton Transactions, Vol.39 (No.5). pp. 1395-1402. doi:10.1039/b915932k ISSN 1477-9226.
Bruker Daltonics
Wootton, Christopher, Millett, Adam J., Lopez-Clavijo, Andrea F., Chiu, Cookson, Barrow, Mark P., Clarkson, Guy J., Sadler, P. J. and O'Connor, Peter B. (2019) Structural analysis of peptides modified with organo-iridium complexes, opportunities from multi-mode fragmentation. Analyst, 144 (5). pp. 1575-1581. doi:10.1039/C8AN02094A ISSN 0003-2654.
Bruker Analytische Meßtechnik GmbH
Banerjee, Samya, Soldevila-Barreda, Joan J., Wolny, Juliusz A., Wootton, Christopher, Habtemariam, Abraha, Romero-Canelón, Isolda, Chen, Feng, Clarkson, Guy J., Prokes, Ivan, Song, Lijiang, O'Connor, Peter B., Schünemann, Volker and Sadler, P. J. (2018) New activation mechanism for half-sandwich organometallic anticancer complexes. Chemical Science, 9 (12). pp. 3177-3185. doi:10.1039/c7sc05058e ISSN 2041-6539.
Del Grosso, Alessandro, Galanopoulos, Lavrentis-Dimitrios, Chiu, Cookson K. C., Clarkson, Guy J., O'Connor, Peter B. and Wills, Martin (2017) Strained alkynes derived from 2,2′-dihydroxy-1,1′-biaryls ; synthesis and copper-free cycloaddition with azides. Organic & Biomolecular Chemistry, 15 (21). 4517-4521 . doi:10.1039/C7OB00991G ISSN 1477-0520.
Consejo Nacional de Ciencia y Tecnología (Mexico) [Mexican Council for Science and Technology] (CONACYT)
Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9 ISSN 0949-8257.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Consejo Nacional de Ciencia y Tecnología (Mexico) [Mexican Council for Science and Technology] (CONACYT)
Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. doi:10.1002/ejic.201100250 ISSN 1434-1948.
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Breeze, Matthew, Chamberlain, Thomas W., Clarkson, Guy J., de Camargo, Raíssa Pires, Wu, Yue, Millange, Franck, Serra, Osvaldo A., O'Hare, Dermot, de Lima, Juliana Fonseca and Walton, Richard I. (2017) Structural variety in ytterbium dicarboxylate frameworks and in situ study diffraction of their solvothermal crystallisation. CrystEngCommun, 19 (17). pp. 2424-2433. ISSN 1466-8033.
Czech Republic. Ministerstvo školství, mládeže a tělovýchovy [Ministry of Education, Youth, and Sport]
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Czech Republic. National Foundation
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Czech Science Foundation (CSF)
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Deutsche Akademie der Naturforscher Leopoldina (DANL)
Altieri, Andrea, Aucagne, Vincent, Carrillo, Romen, Clarkson, Guy J., D'Souza, Daniel M., Dunnett, Jennifer A., Leigh, David A. and Mullen, Kathleen M. (2011) Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science, Vol.2 (No.10). pp. 1922-1928. doi:10.1039/c1sc00335f ISSN 2041-6520.
Engineering and Physical Sciences Research Council (EPSRC)
Bisset, Alexander A., Dishington, Allan, Jones, Teyrnon C., Clarkson, Guy J. and Wills, Martin (2019) Data for Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines. [Dataset]
Shaw, Paul Anthony, Clarkson, Guy J. and Rourke, Jonathan (2017) Oxidation of an o -tolyl phosphine complex of platinum : C-H activation and transcyclometallation. Journal of Organometallic Chemistry, 851 . pp. 115-121. doi:10.1016/j.jorganchem.2017.09.026 ISSN 0022-328X.
Brown, Thomas Joseph, Cumbes, Madeleine, Diorazio, Louis J., Clarkson, Guy J. and Wills, Martin (2017) Use of (Cyclopentadienone)iron tricarbonyl complexes for C–N bond formation reactions between amines and alcohols. The Journal of Organic Chemistry, 82 (19). pp. 10489-10503. doi:10.1021/acs.joc.7b01990 ISSN 0022-3263.
Mitchell, Daniel E., Clarkson, Guy J., Fox, David J., Vipond, Rebecca A. (Ann), Scott, Peter and Gibson, Matthew I. (2017) Antifreeze protein mimetic metallohelices with potent ice recrystallization inhibition activity. Journal of the American Chemical Society, 139 (29). pp. 9835-9838. doi:10.1021/jacs.7b05822 ISSN 0002-7863.
Del Grosso, Alessandro, Galanopoulos, Lavrentis-Dimitrios, Chiu, Cookson K. C., Clarkson, Guy J., O'Connor, Peter B. and Wills, Martin (2017) Strained alkynes derived from 2,2′-dihydroxy-1,1′-biaryls ; synthesis and copper-free cycloaddition with azides. Organic & Biomolecular Chemistry, 15 (21). 4517-4521 . doi:10.1039/C7OB00991G ISSN 1477-0520.
Shaw, Paul Anthony, Clarkson, Guy J. and Rourke, Jonathan (2017) Reversible C–C bond formation at a triply cyclometallated platinum(iv) centre. Chemical Science . doi:10.1039/C7SC01361B ISSN 2041-6520.
Breeze, Matthew, Chamberlain, Thomas W., Clarkson, Guy J., de Camargo, Raíssa Pires, Wu, Yue, Millange, Franck, Serra, Osvaldo A., O'Hare, Dermot, de Lima, Juliana Fonseca and Walton, Richard I. (2017) Structural variety in ytterbium dicarboxylate frameworks and in situ study diffraction of their solvothermal crystallisation. CrystEngCommun, 19 (17). pp. 2424-2433. ISSN 1466-8033.
Pancholi, Alpa K., Geden, Joanna V., Clarkson, Guy J. and Shipman, Michael (2016) Asymmetric synthesis of 2-substituted Azetidin-3-ones via metalated SAMP/RAMP hydrazones. Journal of Organic Chemistry, 81 (17). pp. 7984-7992. doi:10.1021/acs.joc.6b01284 ISSN 0022-3263.
Shaw, Paul Anthony, Phillips, Jessica M., Clarkson, Guy J. and Rourke, Jonathan (2016) Trapping five-coordinate platinum(IV) intermediates. Dalton Transactions, 45 (28). 11397-11406 . doi:10.1039/c6dt02088g ISSN 1477-9226.
Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition, 55 (31). pp. 8909-8912. doi:10.1002/anie.201602995 ISSN 1433-7851.
Wu, Yue, Breeze, Matthew , Clarkson, Guy J., Millange, Franck, O'Hare, Dermot and Walton, Richard I. (2016) Exchange of coordinated solvent during crystallisation of a metal-organic framework observed by in situ high energy X-ray diffraction. Angewandte Chemie International Edition, 55 (16). pp. 4992-4996. doi:10.1002/anie.201600896 ISSN 1433-7851.
Hodgkinson, Roy, Del Grosso, Alessandro, Clarkson, Guy J. and Wills, Martin (2016) Iron cyclopentadienone complexes derived from C2-symmetric bis-propargylic alcohols; preparation and applications to catalysis. Dalton Transactions, 45 . pp. 3992-4005. doi:10.1039/c5dt04610f ISSN 1477-9226.
Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G. and Sadler, P. J. (2016) Combatting AMR : photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity. Chemical Science, 8 (1). pp. 395-404. doi:10.1039/C6SC03028A ISSN 2041-6520.
Shipman, Michael, Beadle, Jonathan D., Powell, Nicola Helen, Raubo, Piotr and Clarkson, Guy J. (2015) Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework. Synlett, 27 (1). pp. 169-172. doi:10.1055/s-0035-1560593 ISSN 0936-5214.
Liu, Ruixia, Zhou, Gang, Hall, Thomas Howard, Clarkson, Guy J., Wills, Martin and Chen, Weiping (2015) Practical access to planar chiral 1,2-(α-Ketotetramethylene)- ferrocene by non-enzymatic kinetic resolution and conclusive confirmation of its absolute configuration. Advanced Synthesis & Catalysis, 357 (16-17). pp. 3453-3457. doi:10.1002/adsc.201500728 ISSN 1615-4150.
Soni, Rina, Hall, Thomas Howard, Morris, David J., Clarkson, Guy J., Owen, Matthew R. and Wills, Martin (2015) N-Functionalised TsDPEN catalysts for asymmetric transfer hydrogenation; synthesis and applications. Tetrahedron Letters, 56 (46). pp. 6397-6401. doi:10.1016/j.tetlet.2015.09.135 ISSN 0040-4039.
Coe, Samuel, Pereira, Nicole, Geden, Joanna V., Clarkson, Guy J., Fox, David J., Napier, R. (Richard), Neve, Paul and Shipman, Michael (2015) Ring closing metathesis reactions of α-methylene-β-lactams : application to the synthesis of a simplified phyllostictine analogue with herbicidal activity. Organic & biomolecular chemistry, Volume 13 (Number 28). pp. 7655-7663. doi:10.1039/c5ob00890e ISSN 1477-0520.
Millett, Adam J., Habtemariam, Abraha, Romero-Canelón, Isolda, Clarkson, Guy J. and Sadler, P. J. (2015) Contrasting anticancer activity of half-sandwich iridium(III) complexes bearing functionally diverse 2-phenylpyridine ligands. Organometallics, Volume 34 (Number 11). pp. 2683-2694. doi:10.1021/acs.organomet.5b00097 ISSN 0276-7333.
Shaw, Paul Anthony, Phillips, Jessica M., Newman, Christopher P., Clarkson, Guy J. and Rourke, Jonathan (2015) Intramolecular transcyclometallation : the exchange of an aryl–Pt bond for an alkyl–Pt bond via an agostic intermediate. Chemical Communications, Volume 51 (Number 39). pp. 8365-8368. doi:10.1039/c5cc02355f ISSN 1359-7345.
Coverdale, James P. C., Sanchez-Cano, Carlos, Clarkson, Guy J., Soni, Rina, Wills, Martin and Sadler, P. J. (2015) Easy to synthesize, robust organo-osmium asymmetric transfer hydrogenation catalysts. Chemistry - A European Journal, 21 (22). pp. 8043-8046. doi:10.1002/chem.201500534 ISSN 0947-6539.
Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2015) Tethered Ru(II) catalysts containing a Ru–I bond. Journal of Organometallic Chemistry, 776 . pp. 157-162. doi:10.1016/j.jorganchem.2014.10.033 ISSN 0022-328X.
Bisset, Alexander A., Dishington, Allan, Jones, Teyrnon C., Clarkson, Guy J. and Wills, Martin (2014) Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines. Tetrahedron, 70 (40). pp. 7207-7220. doi:10.1016/j.tet.2014.06.046 ISSN 0040-4020 .
Faulkner, Alan D., Kaner, Rebecca A., Abdallah, Qasem M. A., Clarkson, Guy J., Fox, David J., Gurnani, Pratik, Howson, Suzanne E., Phillips, Roger M. , Roper, David I., Simpson, Daniel H. and Scott, Peter (2014) Asymmetric triplex metallohelices with high and selective activity against cancer cells. Nature Chemistry, Volume 6 (Number 9). pp. 797-803. doi:10.1038/nchem.2024 ISSN 1755-4330.
Rochford, Luke A., Keeble, Dean Samuel, Holmes, O. J., Clarkson, Guy J. and Jones, T. S. (Tim S.) (2014) Controlling templating effects at the organic/inorganic interface using (111) oriented copper iodide. Journal of Materials Chemistry C, Volume 2 (Number 30). pp. 6056-6060. doi:10.1039/c4tc00759j ISSN 2050-7526.
Liu, Zhe , Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. doi:10.1002/anie.201311161 ISSN 1433-7851.
Beecham, Matthew P., Clarkson, Guy J., Hall, Gareth and Marsh, Andrew (2013) Nanostructures from self-assembling triazine tertiary amine N-oxide amphiphiles. ChemPhysChem, Volume 14 (Number 17). pp. 3909-3915. doi:10.1002/cphc.201300775 ISSN 1439-4235.
Geden, Joanna V., Beasley, Benjamin, Clarkson, Guy J. and Shipman, Michael (2013) Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones. The Journal of Organic Chemistry, Volume78 (Number 23). pp. 12243-12250. doi:10.1021/jo4020485 ISSN 0022-3263.
Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183 ISSN 0947-6539.
Soni, Rina, Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2013) Direct formation of tethered Ru(II) catalysts using arene exchange. Organic Letters, 15 (19). pp. 5110-5113. doi:10.1021/ol4024979 ISSN 1523-7060.
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Bisset, Alexander A., Shiibashi, Akira, Desmond, Jasmine L., Dishington, Allan, Jones, Teyrnon, Clarkson, Guy J., Ikariya, Takao and Wills, Martin (2012) Synthesis and asymmetric hydrogenation of (3E)-1-benzyl-3-[(2-oxopyridin-1(2H)-yl)methylidene]piperidine-2,6-dione. Chemical Communications, 48 (98). pp. 11978-11980. doi:10.1039/c2cc36807b ISSN 1359-7345.
Fu, Y. (Ying), Romero, Maria, Habtemariam, Abraha, Snowden, Michael E., Song, Lijiang, Clarkson, Guy J., Qamar, Bushra, Pizarro, Ana M., Unwin, Patrick R. and Sadler, P. J. (2012) The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexes. Chemical Science, Vol.3 (No.8). pp. 2485-2494. doi:10.1039/c2sc20220d ISSN 2041-6520.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468 ISSN 0276-7333.
Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j ISSN 0020-1669.
Brown, M. J. (Michael J.), Clarkson, Guy J., Inglis, Graham G. and Shipman, Michael (2011) Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis. Organic Letters, Volume 13 (Number 7). pp. 1686-1689. doi:10.1021/ol200193n ISSN 1523-7060.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Johnson, Tarn C., Clarkson, Guy J. and Wills, Martin (2011) (Cyclopentadienone)iron shvo complexes : synthesis and applications to hydrogen transfer reactions. Organometallics, 30 (7). pp. 1859-1868. doi:10.1021/om101101r ISSN 0276-7333.
Chmel, Nikola Paul, Clarkson, Guy J., Troisi, Alessandro, Turner, S. S. and Scott, Peter (2011) Chiral semiconductor phases : the optically pure D3[MIII(S,S-EDDS)]2(D = TTF, TSF) family. Inorganic Chemistry, Vol.50 (No.9). pp. 4039-4046. doi:10.1021/ic102522k ISSN 0020-1669.
Howson, Suzanne E., Allan, Laura E. N., Chmel, Nikola Paul, Clarkson, Guy J., Deeth, Robert J., Faulkner, Alan D., Simpson, Daniel H. and Scott, Peter (2011) Origins of stereoselectivity in optically pure phenylethaniminopyridine tris-chelates M(NN′)3n+ (M = Mn, Fe, Co, Ni and Zn). Dalton Transactions, Vol.40 (No.40). pp. 10416-10433. doi:10.1039/c1dt10588d ISSN 1477-9226.
Sardar, Kripasindhu, Fisher, Janet M., Thompsett, David, Lees, Martin R., Clarkson, Guy J., Sloan, Jeremy, Kashtiban, Reza J. and Walton, Richard I. (2011) Structural variety in iridate oxides and hydroxides from hydrothermal synthesis. Chemical Science, Vol.2 (No.8). pp. 1573-1578. doi:10.1039/c1sc00192b ISSN 2041-6520.
Fu, Y. (Ying), Habtemariam, Abraha, Basri, Aida M. B. H., Braddick, Darren, Clarkson, Guy J. and Sadler, P. J. (2011) Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity. Dalton Transactions (No.40). pp. 10553-10562. doi:10.1039/c1dt10937e ISSN 1477-9226.
Altieri, Andrea, Aucagne, Vincent, Carrillo, Romen, Clarkson, Guy J., D'Souza, Daniel M., Dunnett, Jennifer A., Leigh, David A. and Mullen, Kathleen M. (2011) Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science, Vol.2 (No.10). pp. 1922-1928. doi:10.1039/c1sc00335f ISSN 2041-6520.
Fu, Y. (Ying), Habtemariam, Abraha, Pizarro, Ana M., Rijt, Sabine H. van, Healey, David J., Cooper, Patricia A., Shnyder, Steven D., Clarkson, Guy J. and Sadler, P. J. (2010) Organometallic osmium arene complexes with potent cancer cell cytotoxicity. Journal of Medicinal Chemistry, Vol.53 (No.22). pp. 8192-8196. doi:10.1021/jm100560f ISSN 0022-2623.
Allan, Laura E. N., Clarkson, Guy J., Fox, David J., Gott, Andrew L. and Scott, Peter (2010) Mechanism of catalytic cyclohydroamination by zirconium salicyloxazoline complexes. Journal of the American Chemical Society, Vol.132 (No.43). pp. 15308-15320. doi:10.1021/ja106588m ISSN 0002-7863.
Gosiewska, Silvia, Soni, Rina, Clarkson, Guy J. and Wills, Martin (2010) Synthesis and use of a stable aminal derived from TsDPEN in asymmetric organocatalysis. Tetrahedron Letters, Vol.51 (No.32). pp. 4214-4217. doi:10.1016/j.tetlet.2010.06.017 ISSN 0040-4039.
Amri, Mahrez, Clarkson, Guy J. and Walton, Richard I. (2010) Anisotropic thermal expansion of SiO2 and AlPO4 clathrasils with the AST-type structure. Journal of Physical Chemistry C, Vol.114 (No.14). pp. 6726-6733. doi:10.1021/jp100368e ISSN 1932-7447.
Vernekar, Sanjeev Kumar V., Hallaq, Hasan Y., Clarkson, Guy J., Thompson, Andrew J., Silvestri, Linda, Lummis, Sarah C. R. and Lochner, Martin (2010) Toward biophysical probes for the 5-HT3 receptor : structure-activity relationship study of granisetron derivatives. Journal of Medicinal Chemistry, Vol.53 (No.5). pp. 2324-2328. doi:10.1021/jm901827x ISSN 0022-2623.
Brown, Michael J., Clarkson, Guy J., Fox, David J., Inglis, Graham G. and Shipman, Michael (2010) Critical importance of leaving group 'softness' in nucleophilic ring closure reactions of ambident anions to 1,2-diazetidines. Tetrahedron Letters, Vol.51 (No.2). pp. 382-384. doi:10.1016/j.tetlet.2009.11.024 ISSN 0040-4039.
Becker, Jan M., Barker, J., Clarkson, Guy J., van Gorkum, Remy, Johal, Gursharon K., Walton, Richard I. and Scott, Peter (2010) Chirality and diastereoselection in the mu-oxo diiron complexes L2Fe-O-FeL2 (L = bidentate salicylaldiminato). Dalton Transactions, Vol.39 (No.9). pp. 2309-2326. doi:10.1039/b905706d ISSN 1477-9226.
Jiang, Xiaoli, London, Emma K., Morris, David J., Clarkson, Guy J. and Wills, Martin (2010) Gold-catalysed cyclic ether formation from diols. Tetrahedron, Vol.66 (No.52). pp. 9828-9834. doi:10.1016/j.tet.2010.10.068 ISSN 0040-4020 .
Cheung, Fung Kei, Clarke, Adam J., Clarkson, Guy J., Fox, David J., Graham, Mark A., Lin, Changxue, Crivillé, Adriana Lorente and Wills, Martin (2010) Kinetic and structural studies on 'tethered' Ru(II) arene ketone reduction catalysts. Dalton Transactions, Vol.39 (No.5). pp. 1395-1402. doi:10.1039/b915932k ISSN 1477-9226.
Chmel, Nikola Paul, Howson, Suzanne E., Allan, Laura E. N., Barker, J., Clarkson, Guy J., Turner, S. S. and Scott, Peter (2010) Organic-soluble optically pure anionic metal complexes PPh4[M-III(S,S-EDDS)]center dot 2H(2)O (M = Fe, Co, Cr). Dalton Transactions, Vol.39 (No.11). pp. 2919-2927. doi:10.1039/b924787d ISSN 1477-9226.
Sebli, Cynthia Paul, Howson, Suzanne E., Clarkson, Guy J. and Scott, Peter (2010) fac-Specific syntheses of homochiral [Fe(NN ')(3)](2+) complexes (NN ' = pyridine keto-hydrazone); origins of the stereoselectivity. Dalton Transactions, Vol.39 (No.18). pp. 4447-4454. doi:10.1039/c000815j ISSN 1477-9226.
Rijt, Sabine H. van, Hebden, Andrew J., Amaresekera, Thakshila, Deeth, Robert J., Clarkson, Guy J., Parsons, S. (Simon), McGowan, Patrick C. and Sadler, P. J. (2009) Amide linkage isomerism as an activity switch for organometallic osmium and ruthenium anticancer complexes. Journal of Medicinal Chemistry, Vol.52 (No.23). pp. 7753-7764. doi:10.1021/jm900731j ISSN 0022-2623.
Morris, David J., Clarkson, Guy J. and Wills, Martin (2009) Insights into hydrogen generation from formic acid using ruthenium complexes. Organometallics, Vol.28 (No.14). pp. 4133-4140. doi:10.1021/om900099u ISSN 0276-7333.
Williams, Jennifer J., Lethbridge, Zoe A. D., Clarkson, Guy J., Ashbrook, Sharon E., Evans, K. E. (Kenneth E.) and Walton, Richard I. (2009) The bulk material dissolution method with small amines for the synthesis of large crystals of the siliceous zeolites ZSM-22 and ZSM-48. Microporous and Mesoporous Materials, Vol.119 (No.1-3). pp. 259-266. doi:10.1016/j.micromeso.2008.10.023 ISSN 1387-1811.
Martins, Jose E. D., Clarkson, Guy J. and Wills, Martin (2009) Ru(II) complexes of N-Alkylated TsDPEN ligands in asymmetric transfer hydrogenation of ketones and imines. Organic Letters, Vol.11 (No.4). pp. 847-850. doi:10.1021/ol802801p ISSN 1523-7060.
Musio, Biagia, Clarkson, Guy J., Shipman, Michael, Florio, Saverio and Luisi, Renzo (2009) Synthesis of optically active arylaziridines by regio- and stereospecific lithiation of N-Bus-phenylaziridine. Organic Letters, Vol.11 (No.2). pp. 325-328. doi:10.1021/ol802487v ISSN 1523-7060.
Lethbridge, Zoe A. D., Clarkson, Guy J., Turner, S. S. (Scott S.) and Walton, Richard I. (2009) Polymorphism and variable structural dimensionality in the iron(III) phosphate oxalate system : a new polymorph of 3D [Fe-2(HPO4)(2)(C2O4)(H2O)(2)]center dot 2H(2)O and the layered material [Fe-2(HPO4)(2)(C2O4)(H2O)(2)]. Dalton Transactions (No.42). pp. 9176-9182. doi:10.1039/b911757a ISSN 1477-9226.
Howson, Suzanne E., Allan, Laura E. N., Chmel, Nikola Paul, Clarkson, Guy J., van Gorkum, Remy and Scott, Peter (2009) Self-assembling optically pure Fe(A-B)(3) chelates. Chemical Communications, Vol.45 (No.13). pp. 1727-1729. doi:10.1039/b821573a ISSN 1359-7345.
Cariou, Claire C. A., Clarkson, Guy J. and Shipman, Michael (2008) Rapid synthesis of 1,3,4,4-tetrasubstituted beta-lactams from methyleneaziridines using a four-component reaction. The Journal of Organic Chemistry, Vol.73 (No.24). pp. 9762-9764. doi:10.1021/jo801664g ISSN 0022-3263.
Gott, Andrew L., Clarke, Adam J., Clarkson, Guy J., Munslow, Ian J., Wade, A. R. and Scott, Peter (2008) Single diastereomer half-sandwich salicyloxazoline complexes of titanium and zirconium. Organometallics, Vol.27 (No.12). pp. 2706-2714. doi:10.1021/om8002027 ISSN 0276-7333.
Wynne, Emma L., Clarkson, Guy J. and Shipman, Michael (2008) Stereocontrolled approach to 1-azabicyclo[4.1.0]heptanes : application to the synthesis of trans-2,6-disubstituted piperidines. Tetrahedron Letters, Volume 49 (Number 2). pp. 250-252. doi:10.1016/j.tetlet.2007.11.077 ISSN 0040-4039.
Gott, Andrew L., Clarke, Adam J., Clarkson, Guy J. and Scott, Peter (2008) Catalytic alkene cyclohydroamination via an imido mechanism. Chemical Communications, Vol.44 (No.12). pp. 1422-1424. doi:10.1039/b718373a ISSN 1359-7345.
Gott, Andrew L., Clarkson, Guy J., Deeth, Robert J., Hammond, Max L., Morton, Colin and Scott, Peter (2008) Constrained geometry aminooxazolinate ligands giving chiral zirconium guanidinates; catalytic cyclohydroamination. Dalton Transactions (No.22). pp. 2983-2990. doi:10.1039/b803831g ISSN 1477-9226.
Pascu, Mirela, Clarkson, Guy J., Kariuki, Benson M. and Hannon, M. J. (Michael J.) (2006) Aggregation of imine-based metallo-supramolecular architectures through pi-pi interactions. Dalton Transactions (No.22). pp. 2635-2642. doi:10.1039/b517643c ISSN 1477-9226.
Engineering and Physical Sciences Research Council (EPSRC)
Soni, Rina, Cheung, Fung Kei, Clarkson, Guy J., Martins, Jose E. D., Graham, Mark A. and Wills, Martin (2011) The importance of the N–H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ketones and imines. Organic & Biomolecular Chemistry, 9 (9). pp. 3290-3294. doi:10.1039/c1ob05208j ISSN 1477-0520.
Farrer, Nicola J., Woods, Julie A., Salassa, Luca, Zhao, Yao, (Researcher in chemistry), Robinson, Kim S., Clarkson, Guy J., Mackay, Fiona S. and Sadler, P. J. (2010) A potent trans-diimine platinum anticancer complex photoactivated by visible light. Angewandte Chemie International Edition, Vol.49 (No.47). pp. 8905-8908. doi:10.1002/anie.201003399 ISSN 1433-7851.
European Commission (EC)
Wu, Yue, Breeze, Matthew , Clarkson, Guy J., Millange, Franck, O'Hare, Dermot and Walton, Richard I. (2016) Exchange of coordinated solvent during crystallisation of a metal-organic framework observed by in situ high energy X-ray diffraction. Angewandte Chemie International Edition, 55 (16). pp. 4992-4996. doi:10.1002/anie.201600896 ISSN 1433-7851.
European Commission (EC)
Farrer, Nicola J., Woods, Julie A., Salassa, Luca, Zhao, Yao, (Researcher in chemistry), Robinson, Kim S., Clarkson, Guy J., Mackay, Fiona S. and Sadler, P. J. (2010) A potent trans-diimine platinum anticancer complex photoactivated by visible light. Angewandte Chemie International Edition, Vol.49 (No.47). pp. 8905-8908. doi:10.1002/anie.201003399 ISSN 1433-7851.
European Cooperation in the Field of Scientific and Technical Research (Organization) (COST)
Ragazzon, Giulio, Bratsos, Ioannis, Alessio, E. (Enzo), Salassa, Luca, Habtemariam, Abraha, McQuitty, Ruth J., Clarkson, Guy J. and Sadler, P. J. (2012) Design of photoactivatable metallodrugs : selective and rapid light-induced ligand dissociation from half-sandwich [Ru([9]aneS3)(N–N′)(py)]2+ complexes. Inorganica Chimica Acta, Vol.393 . pp. 230-238. doi:10.1016/j.ica.2012.06.031 ISSN 0020-1693.
Parajo, Yolanda, Malina, J. (Jaroslav), Meistermann, Isabelle, Clarkson, Guy J., Pascu, Mirela, Rodger, Alison, Hannon, M. J. (Michael J.) and Lincoln, Per (2009) Effect of bridging ligand structure on the thermal stability and DNA binding properties of iron(II) triple helicates. Dalton Transactions (No.25). pp. 4868-4874. doi:10.1039/b822039e ISSN 1477-9226.
European Regional Development Fund
Crosby, Sarah H., Clarkson, Guy J., Deeth, Robert J. and Rourke, Jonathan (2010) Platinum(IV) DMSO complexes : synthesis, isomerization, and agostic intermediates. Organometallics, Vol.29 (No.8). pp. 1966-1976. doi:10.1021/om901087m ISSN 0276-7333.
European Regional Development Fund (ERDF)
Shaw, Paul Anthony, Clarkson, Guy J. and Rourke, Jonathan (2017) Oxidation of an o -tolyl phosphine complex of platinum : C-H activation and transcyclometallation. Journal of Organometallic Chemistry, 851 . pp. 115-121. doi:10.1016/j.jorganchem.2017.09.026 ISSN 0022-328X.
Brown, Thomas Joseph, Cumbes, Madeleine, Diorazio, Louis J., Clarkson, Guy J. and Wills, Martin (2017) Use of (Cyclopentadienone)iron tricarbonyl complexes for C–N bond formation reactions between amines and alcohols. The Journal of Organic Chemistry, 82 (19). pp. 10489-10503. doi:10.1021/acs.joc.7b01990 ISSN 0022-3263.
Shaw, Paul Anthony, Clarkson, Guy J. and Rourke, Jonathan (2017) Reversible C–C bond formation at a triply cyclometallated platinum(iv) centre. Chemical Science . doi:10.1039/C7SC01361B ISSN 2041-6520.
Shaw, Paul Anthony, Phillips, Jessica M., Clarkson, Guy J. and Rourke, Jonathan (2016) Trapping five-coordinate platinum(IV) intermediates. Dalton Transactions, 45 (28). 11397-11406 . doi:10.1039/c6dt02088g ISSN 1477-9226.
Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition, 55 (31). pp. 8909-8912. doi:10.1002/anie.201602995 ISSN 1433-7851.
Shaw, Paul Anthony, Phillips, Jessica M., Newman, Christopher P., Clarkson, Guy J. and Rourke, Jonathan (2015) Intramolecular transcyclometallation : the exchange of an aryl–Pt bond for an alkyl–Pt bond via an agostic intermediate. Chemical Communications, Volume 51 (Number 39). pp. 8365-8368. doi:10.1039/c5cc02355f ISSN 1359-7345.
Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2015) Tethered Ru(II) catalysts containing a Ru–I bond. Journal of Organometallic Chemistry, 776 . pp. 157-162. doi:10.1016/j.jorganchem.2014.10.033 ISSN 0022-328X.
Liu, Zhe , Romero-Canelón, Isolda, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2014) Potent half-sandwich iridium(III) anticancer complexes containing C∧N-Chelated and pyridine ligands. Organometallics, 33 (19). pp. 5324-5333. doi:10.1021/om500644f ISSN 0276-7333.
Rochford, Luke A., Keeble, Dean Samuel, Holmes, O. J., Clarkson, Guy J. and Jones, T. S. (Tim S.) (2014) Controlling templating effects at the organic/inorganic interface using (111) oriented copper iodide. Journal of Materials Chemistry C, Volume 2 (Number 30). pp. 6056-6060. doi:10.1039/c4tc00759j ISSN 2050-7526.
Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183 ISSN 0947-6539.
Soni, Rina, Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2013) Direct formation of tethered Ru(II) catalysts using arene exchange. Organic Letters, 15 (19). pp. 5110-5113. doi:10.1021/ol4024979 ISSN 1523-7060.
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Darwish, Moftah O., Wallace, Alistair, Clarkson, Guy J. and Wills, Martin (2013) Use of tridentate TsDPEN/pyridine ligands in ruthenium-catalysed asymmetric reduction of ketones. Tetrahedron Letters, 54 (32). pp. 4250-4253. doi:10.1016/j.tetlet.2013.05.141 ISSN 0040-4039.
Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9 ISSN 0949-8257.
Crosby, Sarah H., Thomas, Helen R., Clarkson, Guy J. and Rourke, Jonathan (2012) Concerted reductive coupling of an alkyl chloride at Pt(IV). Chemical Communications, Vol.48 (No.46). pp. 5775-5777. doi:10.1039/c2cc31572f ISSN 1359-7345.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Bisset, Alexander A., Shiibashi, Akira, Desmond, Jasmine L., Dishington, Allan, Jones, Teyrnon, Clarkson, Guy J., Ikariya, Takao and Wills, Martin (2012) Synthesis and asymmetric hydrogenation of (3E)-1-benzyl-3-[(2-oxopyridin-1(2H)-yl)methylidene]piperidine-2,6-dione. Chemical Communications, 48 (98). pp. 11978-11980. doi:10.1039/c2cc36807b ISSN 1359-7345.
Fu, Y. (Ying), Romero, Maria, Habtemariam, Abraha, Snowden, Michael E., Song, Lijiang, Clarkson, Guy J., Qamar, Bushra, Pizarro, Ana M., Unwin, Patrick R. and Sadler, P. J. (2012) The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexes. Chemical Science, Vol.3 (No.8). pp. 2485-2494. doi:10.1039/c2sc20220d ISSN 2041-6520.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468 ISSN 0276-7333.
Crosby, Sarah H., Clarkson, Guy J. and Rourke, Jonathan (2011) Reactions of a platinum(II) agostic complex : decyclometalation, dicyclometalation, and solvent-switchable formation of a rollover complex. Organometallics, Vol.30 (No.13). pp. 3603-3609. doi:10.1021/om200293e ISSN 0276-7333.
Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. doi:10.1002/ejic.201100250 ISSN 1434-1948.
Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j ISSN 0020-1669.
Brown, M. J. (Michael J.), Clarkson, Guy J., Inglis, Graham G. and Shipman, Michael (2011) Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis. Organic Letters, Volume 13 (Number 7). pp. 1686-1689. doi:10.1021/ol200193n ISSN 1523-7060.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Johnson, Tarn C., Clarkson, Guy J. and Wills, Martin (2011) (Cyclopentadienone)iron shvo complexes : synthesis and applications to hydrogen transfer reactions. Organometallics, 30 (7). pp. 1859-1868. doi:10.1021/om101101r ISSN 0276-7333.
Crosby, Sarah H., Deeth, Robert J., Clarkson, Guy J. and Rourke, Jonathan (2011) Platinum(iv) centres with agostic interactions from either sp2 or sp3 C–H bonds. Dalton Transactions, Vol.40 (No.6). pp. 1227-1229. doi:10.1039/c0dt01428a ISSN 1477-9226.
Fu, Y. (Ying), Habtemariam, Abraha, Basri, Aida M. B. H., Braddick, Darren, Clarkson, Guy J. and Sadler, P. J. (2011) Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity. Dalton Transactions (No.40). pp. 10553-10562. doi:10.1039/c1dt10937e ISSN 1477-9226.
Fu, Y. (Ying), Habtemariam, Abraha, Pizarro, Ana M., Rijt, Sabine H. van, Healey, David J., Cooper, Patricia A., Shnyder, Steven D., Clarkson, Guy J. and Sadler, P. J. (2010) Organometallic osmium arene complexes with potent cancer cell cytotoxicity. Journal of Medicinal Chemistry, Vol.53 (No.22). pp. 8192-8196. doi:10.1021/jm100560f ISSN 0022-2623.
Gosiewska, Silvia, Soni, Rina, Clarkson, Guy J. and Wills, Martin (2010) Synthesis and use of a stable aminal derived from TsDPEN in asymmetric organocatalysis. Tetrahedron Letters, Vol.51 (No.32). pp. 4214-4217. doi:10.1016/j.tetlet.2010.06.017 ISSN 0040-4039.
Morris, David J., Clarkson, Guy J. and Wills, Martin (2009) Insights into hydrogen generation from formic acid using ruthenium complexes. Organometallics, Vol.28 (No.14). pp. 4133-4140. doi:10.1021/om900099u ISSN 0276-7333.
European Regional Development Fund (ERDF)
Sardar, Kripasindhu, Fisher, Janet M., Thompsett, David, Lees, Martin R., Clarkson, Guy J., Sloan, Jeremy, Kashtiban, Reza J. and Walton, Richard I. (2011) Structural variety in iridate oxides and hydroxides from hydrothermal synthesis. Chemical Science, Vol.2 (No.8). pp. 1573-1578. doi:10.1039/c1sc00192b ISSN 2041-6520.
European Research Council (ERC)
Mitchell, Daniel E., Clarkson, Guy J., Fox, David J., Vipond, Rebecca A. (Ann), Scott, Peter and Gibson, Matthew I. (2017) Antifreeze protein mimetic metallohelices with potent ice recrystallization inhibition activity. Journal of the American Chemical Society, 139 (29). pp. 9835-9838. doi:10.1021/jacs.7b05822 ISSN 0002-7863.
Rajkumar, Sundaram, Clarkson, Guy J. and Shipman, Michael (2017) Regio- and stereocontrolled synthesis of 3-substituted 1,2-diazetidines by asymmetric allylic amination of vinyl epoxide. Organic Letters, 19 (8). pp. 2058-2061. doi:10.1021/acs.orglett.7b00653 ISSN 1523-7060.
Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition, 55 (31). pp. 8909-8912. doi:10.1002/anie.201602995 ISSN 1433-7851.
Smith, Nichola A., Zhang, Pingyu, Greenough, Simon E., Horbury, Michael D., Clarkson, Guy J., McFeely, Daniel, Habtemariam, Abraha, Salassa, Luca, Stavros, Vasilios G., Dowson, Christopher G. and Sadler, P. J. (2016) Combatting AMR : photoactivatable ruthenium(ii)-isoniazid complex exhibits rapid selective antimycobacterial activity. Chemical Science, 8 (1). pp. 395-404. doi:10.1039/C6SC03028A ISSN 2041-6520.
Millett, Adam J., Habtemariam, Abraha, Romero-Canelón, Isolda, Clarkson, Guy J. and Sadler, P. J. (2015) Contrasting anticancer activity of half-sandwich iridium(III) complexes bearing functionally diverse 2-phenylpyridine ligands. Organometallics, Volume 34 (Number 11). pp. 2683-2694. doi:10.1021/acs.organomet.5b00097 ISSN 0276-7333.
Coverdale, James P. C., Sanchez-Cano, Carlos, Clarkson, Guy J., Soni, Rina, Wills, Martin and Sadler, P. J. (2015) Easy to synthesize, robust organo-osmium asymmetric transfer hydrogenation catalysts. Chemistry - A European Journal, 21 (22). pp. 8043-8046. doi:10.1002/chem.201500534 ISSN 0947-6539.
Liu, Zhe , Romero-Canelón, Isolda, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2014) Potent half-sandwich iridium(III) anticancer complexes containing C∧N-Chelated and pyridine ligands. Organometallics, 33 (19). pp. 5324-5333. doi:10.1021/om500644f ISSN 0276-7333.
Liu, Zhe , Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. doi:10.1002/anie.201311161 ISSN 1433-7851.
Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183 ISSN 0947-6539.
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9 ISSN 0949-8257.
Ragazzon, Giulio, Bratsos, Ioannis, Alessio, E. (Enzo), Salassa, Luca, Habtemariam, Abraha, McQuitty, Ruth J., Clarkson, Guy J. and Sadler, P. J. (2012) Design of photoactivatable metallodrugs : selective and rapid light-induced ligand dissociation from half-sandwich [Ru([9]aneS3)(N–N′)(py)]2+ complexes. Inorganica Chimica Acta, Vol.393 . pp. 230-238. doi:10.1016/j.ica.2012.06.031 ISSN 0020-1693.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Fu, Y. (Ying), Romero, Maria, Habtemariam, Abraha, Snowden, Michael E., Song, Lijiang, Clarkson, Guy J., Qamar, Bushra, Pizarro, Ana M., Unwin, Patrick R. and Sadler, P. J. (2012) The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexes. Chemical Science, Vol.3 (No.8). pp. 2485-2494. doi:10.1039/c2sc20220d ISSN 2041-6520.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468 ISSN 0276-7333.
Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. doi:10.1002/ejic.201100250 ISSN 1434-1948.
Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j ISSN 0020-1669.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Fu, Y. (Ying), Habtemariam, Abraha, Basri, Aida M. B. H., Braddick, Darren, Clarkson, Guy J. and Sadler, P. J. (2011) Structure–activity relationships for organometallic osmium arene phenylazopyridine complexes with potent anticancer activity. Dalton Transactions (No.40). pp. 10553-10562. doi:10.1039/c1dt10937e ISSN 1477-9226.
Altieri, Andrea, Aucagne, Vincent, Carrillo, Romen, Clarkson, Guy J., D'Souza, Daniel M., Dunnett, Jennifer A., Leigh, David A. and Mullen, Kathleen M. (2011) Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science, Vol.2 (No.10). pp. 1922-1928. doi:10.1039/c1sc00335f ISSN 2041-6520.
European Union (EU)
Parajo, Yolanda, Malina, J. (Jaroslav), Meistermann, Isabelle, Clarkson, Guy J., Pascu, Mirela, Rodger, Alison, Hannon, M. J. (Michael J.) and Lincoln, Per (2009) Effect of bridging ligand structure on the thermal stability and DNA binding properties of iron(II) triple helicates. Dalton Transactions (No.25). pp. 4868-4874. doi:10.1039/b822039e ISSN 1477-9226.
Fondazione Beneficentia Stiftung
Ragazzon, Giulio, Bratsos, Ioannis, Alessio, E. (Enzo), Salassa, Luca, Habtemariam, Abraha, McQuitty, Ruth J., Clarkson, Guy J. and Sadler, P. J. (2012) Design of photoactivatable metallodrugs : selective and rapid light-induced ligand dissociation from half-sandwich [Ru([9]aneS3)(N–N′)(py)]2+ complexes. Inorganica Chimica Acta, Vol.393 . pp. 230-238. doi:10.1016/j.ica.2012.06.031 ISSN 0020-1693.
Fundación "Pedro Barrié de la Maza, Conde de Fenosa"
Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183 ISSN 0947-6539.
Fundación Ramón Areces (FRA)
Altieri, Andrea, Aucagne, Vincent, Carrillo, Romen, Clarkson, Guy J., D'Souza, Daniel M., Dunnett, Jennifer A., Leigh, David A. and Mullen, Kathleen M. (2011) Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science, Vol.2 (No.10). pp. 1922-1928. doi:10.1039/c1sc00335f ISSN 2041-6520.
GlaxoSmithKline
Brown, M. J. (Michael J.), Clarkson, Guy J., Inglis, Graham G. and Shipman, Michael (2011) Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis. Organic Letters, Volume 13 (Number 7). pp. 1686-1689. doi:10.1021/ol200193n ISSN 1523-7060.
Brown, Michael J., Clarkson, Guy J., Fox, David J., Inglis, Graham G. and Shipman, Michael (2010) Critical importance of leaving group 'softness' in nucleophilic ring closure reactions of ambident anions to 1,2-diazetidines. Tetrahedron Letters, Vol.51 (No.2). pp. 382-384. doi:10.1016/j.tetlet.2009.11.024 ISSN 0040-4039.
Grantová agentura České republiky [Grant Agency of the Czech Republic] (GACR)
Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9 ISSN 0949-8257.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Guo jia zi ran ke xue ji jin wei yuan hui (China) [National Natural Science Foundation of China] (NSFC)
Liu, Ruixia, Zhou, Gang, Hall, Thomas Howard, Clarkson, Guy J., Wills, Martin and Chen, Weiping (2015) Practical access to planar chiral 1,2-(α-Ketotetramethylene)- ferrocene by non-enzymatic kinetic resolution and conclusive confirmation of its absolute configuration. Advanced Synthesis & Catalysis, 357 (16-17). pp. 3453-3457. doi:10.1002/adsc.201500728 ISSN 1615-4150.
Higher Education Funding Council for England (HEFCE)
Rochford, Luke A., Keeble, Dean Samuel, Holmes, O. J., Clarkson, Guy J. and Jones, T. S. (Tim S.) (2014) Controlling templating effects at the organic/inorganic interface using (111) oriented copper iodide. Journal of Materials Chemistry C, Volume 2 (Number 30). pp. 6056-6060. doi:10.1039/c4tc00759j ISSN 2050-7526.
Johnson Matthey Plc.
Hodgkinson, Roy, Jurčík, Václav, Zanotti-Gerosa, Antonio, Nedden, Hans Günter, Blackaby, Andrew, Clarkson, Guy J. and Wills, Martin (2014) Synthesis and catalytic applications of an extended range of tethered ruthenium(II)/η6-Arene/diamine complexes. Organometallics, Volume 33 (Number 19). pp. 5517-5524. doi:10.1021/om500788t ISSN 0276-7333.
Leverhulme Trust (LT)
Rajkumar, Sundaram, Clarkson, Guy J. and Shipman, Michael (2017) Regio- and stereocontrolled synthesis of 3-substituted 1,2-diazetidines by asymmetric allylic amination of vinyl epoxide. Organic Letters, 19 (8). pp. 2058-2061. doi:10.1021/acs.orglett.7b00653 ISSN 1523-7060.
Hodgkinson, Roy, Del Grosso, Alessandro, Clarkson, Guy J. and Wills, Martin (2016) Iron cyclopentadienone complexes derived from C2-symmetric bis-propargylic alcohols; preparation and applications to catalysis. Dalton Transactions, 45 . pp. 3992-4005. doi:10.1039/c5dt04610f ISSN 1477-9226.
Soni, Rina, Hall, Thomas Howard, Morris, David J., Clarkson, Guy J., Owen, Matthew R. and Wills, Martin (2015) N-Functionalised TsDPEN catalysts for asymmetric transfer hydrogenation; synthesis and applications. Tetrahedron Letters, 56 (46). pp. 6397-6401. doi:10.1016/j.tetlet.2015.09.135 ISSN 0040-4039.
Coverdale, James P. C., Sanchez-Cano, Carlos, Clarkson, Guy J., Soni, Rina, Wills, Martin and Sadler, P. J. (2015) Easy to synthesize, robust organo-osmium asymmetric transfer hydrogenation catalysts. Chemistry - A European Journal, 21 (22). pp. 8043-8046. doi:10.1002/chem.201500534 ISSN 0947-6539.
Soni, Rina, Jolley, Katherine E., Clarkson, Guy J. and Wills, Martin (2013) Direct formation of tethered Ru(II) catalysts using arene exchange. Organic Letters, 15 (19). pp. 5110-5113. doi:10.1021/ol4024979 ISSN 1523-7060.
Libya.
Darwish, Moftah O., Wallace, Alistair, Clarkson, Guy J. and Wills, Martin (2013) Use of tridentate TsDPEN/pyridine ligands in ruthenium-catalysed asymmetric reduction of ketones. Tetrahedron Letters, 54 (32). pp. 4250-4253. doi:10.1016/j.tetlet.2013.05.141 ISSN 0040-4039.
Marie Curie Intra-European Fellowship (IEF)
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Medical Research Council (Great Britain) (MRC)
Boal, Frederic, Guetzoyan, Lucie, Sessions, Richard B., Zeghouf, Mahel, Spooner, Robert A. , Lord, Mike, Cherfils, Jacqueline, Clarkson, Guy J., Roberts, L. M. (Lynne M.) and Stephens, David J. (2010) LG186: an inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells. Traffic, Vol.11 (No.12). pp. 1537-1551. doi:10.1111/j.1600-0854.2010.01122.x ISSN 1398-9219.
Fu, Y. (Ying), Habtemariam, Abraha, Pizarro, Ana M., Rijt, Sabine H. van, Healey, David J., Cooper, Patricia A., Shnyder, Steven D., Clarkson, Guy J. and Sadler, P. J. (2010) Organometallic osmium arene complexes with potent cancer cell cytotoxicity. Journal of Medicinal Chemistry, Vol.53 (No.22). pp. 8192-8196. doi:10.1021/jm100560f ISSN 0022-2623.
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, Frédéric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
Medical Research Council (Great Britain) (MRC)
Farrer, Nicola J., Woods, Julie A., Salassa, Luca, Zhao, Yao, (Researcher in chemistry), Robinson, Kim S., Clarkson, Guy J., Mackay, Fiona S. and Sadler, P. J. (2010) A potent trans-diimine platinum anticancer complex photoactivated by visible light. Angewandte Chemie International Edition, Vol.49 (No.47). pp. 8905-8908. doi:10.1002/anie.201003399 ISSN 1433-7851.
National Institutes of Health (U.S.) (NIH)
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, Frédéric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Netherlands Organisation for Scientific Research] (NWO)
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Overseas Research Students Awards Scheme (ORSAS)
Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9 ISSN 0949-8257.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468 ISSN 0276-7333.
Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. doi:10.1002/ejic.201100250 ISSN 1434-1948.
Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j ISSN 0020-1669.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Peter und Traudl Engelhorn-Stiftung (PTES)
Altieri, Andrea, Aucagne, Vincent, Carrillo, Romen, Clarkson, Guy J., D'Souza, Daniel M., Dunnett, Jennifer A., Leigh, David A. and Mullen, Kathleen M. (2011) Sulfur-containing amide-based [2]rotaxanes and molecular shuttles. Chemical Science, Vol.2 (No.10). pp. 1922-1928. doi:10.1039/c1sc00335f ISSN 2041-6520.
Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung [Swiss National Science Foundation] (SNSF)
Liu, Zhe , Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. doi:10.1002/anie.201311161 ISSN 1433-7851.
Science City Research Alliance
Millett, Adam J., Habtemariam, Abraha, Romero-Canelón, Isolda, Clarkson, Guy J. and Sadler, P. J. (2015) Contrasting anticancer activity of half-sandwich iridium(III) complexes bearing functionally diverse 2-phenylpyridine ligands. Organometallics, Volume 34 (Number 11). pp. 2683-2694. doi:10.1021/acs.organomet.5b00097 ISSN 0276-7333.
Rochford, Luke A., Keeble, Dean Samuel, Holmes, O. J., Clarkson, Guy J. and Jones, T. S. (Tim S.) (2014) Controlling templating effects at the organic/inorganic interface using (111) oriented copper iodide. Journal of Materials Chemistry C, Volume 2 (Number 30). pp. 6056-6060. doi:10.1039/c4tc00759j ISSN 2050-7526.
Liu, Zhe , Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. doi:10.1002/anie.201311161 ISSN 1433-7851.
Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183 ISSN 0947-6539.
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. doi:10.1002/ejic.201100250 ISSN 1434-1948.
Seventh Framework Programme (European Commission) (FP7)
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Siemens Analytical Instruments
Pascu, Mirela, Clarkson, Guy J., Kariuki, Benson M. and Hannon, M. J. (Michael J.) (2006) Aggregation of imine-based metallo-supramolecular architectures through pi-pi interactions. Dalton Transactions (No.22). pp. 2635-2642. doi:10.1039/b517643c ISSN 1477-9226.
Spain. Ministerio de Ciencia e Innovación (MICINN)
Fu, Ying, Soni, Rina, Romero, Maria, Pizarro, Ana M., Salassa, Luca, Clarkson, Guy J., Hearn, Jessica M., Habtemariam, Abraha, Wills, Martin and Sadler, P. J. (2013) Mirror-image organometallic osmium arene iminopyridine halido complexes exhibit similar potent anticancer activity. Chemistry - A European Journal, Volume 19 (Number 45). pp. 15199-15209. doi:10.1002/chem.201302183 ISSN 0947-6539.
Spain. Ministerio de Economía y Competitividad [Ministry of Economy and Competitiveness] (MINECO)
Fu, Ying, Romero, Maria, Salassa, Luca, Cheng, Xi, Habtemariam, Abraha, Clarkson, Guy J., Prokes, Ivan, Rodger, Alison, Costantini, Giovanni and Sadler, P. J. (2016) Os2-Os4 switch controls DNA knotting and anticancer activity. Angewandte Chemie International Edition, 55 (31). pp. 8909-8912. doi:10.1002/anie.201602995 ISSN 1433-7851.
Technology Strategy Board (Great Britain)
Hodgkinson, Roy, Jurčík, Václav, Zanotti-Gerosa, Antonio, Nedden, Hans Günter, Blackaby, Andrew, Clarkson, Guy J. and Wills, Martin (2014) Synthesis and catalytic applications of an extended range of tethered ruthenium(II)/η6-Arene/diamine complexes. Organometallics, Volume 33 (Number 19). pp. 5517-5524. doi:10.1021/om500788t ISSN 0276-7333.
University of Warwick
Del Grosso, Alessandro, Galanopoulos, Lavrentis-Dimitrios, Chiu, Cookson K. C., Clarkson, Guy J., O'Connor, Peter B. and Wills, Martin (2017) Strained alkynes derived from 2,2′-dihydroxy-1,1′-biaryls ; synthesis and copper-free cycloaddition with azides. Organic & Biomolecular Chemistry, 15 (21). 4517-4521 . doi:10.1039/C7OB00991G ISSN 1477-0520.
Hsueh, Nathanael, Clarkson, Guy J. and Shipman, Michael (2016) Functionalization of alkenes through telescoped continuous flow aziridination processes. Organic Letters, 18 (9). pp. 4908-4911. doi:10.1021/acs.orglett.6b02349 ISSN 1523-7060.
Pancholi, Alpa K., Geden, Joanna V., Clarkson, Guy J. and Shipman, Michael (2016) Asymmetric synthesis of 2-substituted Azetidin-3-ones via metalated SAMP/RAMP hydrazones. Journal of Organic Chemistry, 81 (17). pp. 7984-7992. doi:10.1021/acs.joc.6b01284 ISSN 0022-3263.
Shipman, Michael, Beadle, Jonathan D., Powell, Nicola Helen, Raubo, Piotr and Clarkson, Guy J. (2015) Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework. Synlett, 27 (1). pp. 169-172. doi:10.1055/s-0035-1560593 ISSN 0936-5214.
Coe, Samuel, Pereira, Nicole, Geden, Joanna V., Clarkson, Guy J., Fox, David J., Napier, R. (Richard), Neve, Paul and Shipman, Michael (2015) Ring closing metathesis reactions of α-methylene-β-lactams : application to the synthesis of a simplified phyllostictine analogue with herbicidal activity. Organic & biomolecular chemistry, Volume 13 (Number 28). pp. 7655-7663. doi:10.1039/c5ob00890e ISSN 1477-0520.
Faulkner, Alan D., Kaner, Rebecca A., Abdallah, Qasem M. A., Clarkson, Guy J., Fox, David J., Gurnani, Pratik, Howson, Suzanne E., Phillips, Roger M. , Roper, David I., Simpson, Daniel H. and Scott, Peter (2014) Asymmetric triplex metallohelices with high and selective activity against cancer cells. Nature Chemistry, Volume 6 (Number 9). pp. 797-803. doi:10.1038/nchem.2024 ISSN 1755-4330.
Geden, Joanna V., Beasley, Benjamin, Clarkson, Guy J. and Shipman, Michael (2013) Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones. The Journal of Organic Chemistry, Volume78 (Number 23). pp. 12243-12250. doi:10.1021/jo4020485 ISSN 0022-3263.
Fang, Zhijia (Researcher in chemistry), Clarkson, Guy J. and Wills, Martin (2013) Asymmetric reduction of 2,2-dimethyl-6-(2-oxoalkyl/oxoaryl)-1,3-dioxin-4-ones and application to the synthesis of (+)-yashabushitriol. Tetrahedron Letters, Volume 54 (Number 50). pp. 6834-6837. doi:10.1016/j.tetlet.2013.10.010 ISSN 0040-4039.
Crosby, Sarah H., Thomas, Helen R., Clarkson, Guy J. and Rourke, Jonathan (2012) Concerted reductive coupling of an alkyl chloride at Pt(IV). Chemical Communications, Vol.48 (No.46). pp. 5775-5777. doi:10.1039/c2cc31572f ISSN 1359-7345.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic iridium(III) cyclopentadienyl anticancer complexes containing C,N-chelating ligands. Organometallics, Vol.30 (No.17). pp. 4702-4710. doi:10.1021/om2005468 ISSN 0276-7333.
Crosby, Sarah H., Clarkson, Guy J. and Rourke, Jonathan (2011) Reactions of a platinum(II) agostic complex : decyclometalation, dicyclometalation, and solvent-switchable formation of a rollover complex. Organometallics, Vol.30 (No.13). pp. 3603-3609. doi:10.1021/om200293e ISSN 0276-7333.
Liu, Zhe , Salassa, Luca, Habtemariam, Abraha, Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2011) Contrasting reactivity and cancer cell cytotoxicity of isoelectronic organometallic iridium(III) complexes. Inorganic Chemistry, Vol.50 (No.12). pp. 5777-5783. doi:10.1021/ic200607j ISSN 0020-1669.
Liu, Zhe , Habtemariam, Abraha, Pizarro, Ana M., Fletcher, Sally A., Kisova, Anna, Vrana, Oldrich, Salassa, Luca, Bruijnincx, Pieter C. A., Clarkson, Guy J., Brabec, V. (Viktor) and Sadler, P. J. (2011) Organometallic half-sandwich iridium anticancer complexes. Journal of Medicinal Chemistry, Vol.54 (No.8). pp. 3011-3026. doi:10.1021/jm2000932 ISSN 0022-2623.
Howson, Suzanne E., Allan, Laura E. N., Chmel, Nikola Paul, Clarkson, Guy J., Deeth, Robert J., Faulkner, Alan D., Simpson, Daniel H. and Scott, Peter (2011) Origins of stereoselectivity in optically pure phenylethaniminopyridine tris-chelates M(NN′)3n+ (M = Mn, Fe, Co, Ni and Zn). Dalton Transactions, Vol.40 (No.40). pp. 10416-10433. doi:10.1039/c1dt10588d ISSN 1477-9226.
Crosby, Sarah H., Deeth, Robert J., Clarkson, Guy J. and Rourke, Jonathan (2011) Platinum(iv) centres with agostic interactions from either sp2 or sp3 C–H bonds. Dalton Transactions, Vol.40 (No.6). pp. 1227-1229. doi:10.1039/c0dt01428a ISSN 1477-9226.
Gosiewska, Silvia, Soni, Rina, Clarkson, Guy J. and Wills, Martin (2010) Synthesis and use of a stable aminal derived from TsDPEN in asymmetric organocatalysis. Tetrahedron Letters, Vol.51 (No.32). pp. 4214-4217. doi:10.1016/j.tetlet.2010.06.017 ISSN 0040-4039.
Crosby, Sarah H., Clarkson, Guy J., Deeth, Robert J. and Rourke, Jonathan (2010) Platinum(IV) DMSO complexes : synthesis, isomerization, and agostic intermediates. Organometallics, Vol.29 (No.8). pp. 1966-1976. doi:10.1021/om901087m ISSN 0276-7333.
Jiang, Xiaoli, London, Emma K., Morris, David J., Clarkson, Guy J. and Wills, Martin (2010) Gold-catalysed cyclic ether formation from diols. Tetrahedron, Vol.66 (No.52). pp. 9828-9834. doi:10.1016/j.tet.2010.10.068 ISSN 0040-4020 .
Chmel, Nikola Paul, Howson, Suzanne E., Allan, Laura E. N., Barker, J., Clarkson, Guy J., Turner, S. S. and Scott, Peter (2010) Organic-soluble optically pure anionic metal complexes PPh4[M-III(S,S-EDDS)]center dot 2H(2)O (M = Fe, Co, Cr). Dalton Transactions, Vol.39 (No.11). pp. 2919-2927. doi:10.1039/b924787d ISSN 1477-9226.
Crosby, Sarah H., Clarkson, Guy J. and Rourke, Jonathan (2009) A delicate balance between sp(2) and sp(3) C-H bond activation : a Pt(II) complex with a dual agostic interaction. Journal of the American Chemical Society, Vol.131 (No.40). pp. 14142-14143. doi:10.1021/ja905046n ISSN 0002-7863.
Parajo, Yolanda, Malina, J. (Jaroslav), Meistermann, Isabelle, Clarkson, Guy J., Pascu, Mirela, Rodger, Alison, Hannon, M. J. (Michael J.) and Lincoln, Per (2009) Effect of bridging ligand structure on the thermal stability and DNA binding properties of iron(II) triple helicates. Dalton Transactions (No.25). pp. 4868-4874. doi:10.1039/b822039e ISSN 1477-9226.
Howson, Suzanne E., Allan, Laura E. N., Chmel, Nikola Paul, Clarkson, Guy J., van Gorkum, Remy and Scott, Peter (2009) Self-assembling optically pure Fe(A-B)(3) chelates. Chemical Communications, Vol.45 (No.13). pp. 1727-1729. doi:10.1039/b821573a ISSN 1359-7345.
Nalli, Stefano M., Clarkson, Guy J., Franklin, Alison S., Bellone, Graziella and Shipman, Michael (2008) Iminophosphorane-mediated synthesis of cyclic guanidines : application to the synthesis of a simplified NA22598A(1) analogue. Synlett (No.15). pp. 2339-2341. doi:10.1055/s-2008-1078279 ISSN 0936-5214.
Wynne, Emma L., Clarkson, Guy J. and Shipman, Michael (2008) Stereocontrolled approach to 1-azabicyclo[4.1.0]heptanes : application to the synthesis of trans-2,6-disubstituted piperidines. Tetrahedron Letters, Volume 49 (Number 2). pp. 250-252. doi:10.1016/j.tetlet.2007.11.077 ISSN 0040-4039.
University of Warwick
Soni, Rina, Cheung, Fung Kei, Clarkson, Guy J., Martins, Jose E. D., Graham, Mark A. and Wills, Martin (2011) The importance of the N–H bond in Ru/TsDPEN complexes for asymmetric transfer hydrogenation of ketones and imines. Organic & Biomolecular Chemistry, 9 (9). pp. 3290-3294. doi:10.1039/c1ob05208j ISSN 1477-0520.
University of Warwick Postgraduate Research Scholarship
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Betanzos-Lara, Soledad, Novakova, Olga, Deeth, Robert J., Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor), Sadler, P. J. and Habtemariam, Abraha (2012) Bipyrimidine ruthenium(II) arene complexes : structure, reactivity and cytotoxicity. JBIC Journal of Biological Inorganic Chemistry, 17 (7). pp. 1033-1051. doi:10.1007/s00775-012-0917-9 ISSN 0949-8257.
Betanzos-Lara, Soledad, Salassa, Luca, Habtemariam, Abraha, Novakova, Olga, Pizarro, Ana M., Clarkson, Guy J., Liskova, Barbora, Brabec, V. (Viktor) and Sadler, P. J. (2012) Photoactivatable organometallic pyridyl ruthenium(II) arene complexes. Organometallics, Vol.31 (No.9). pp. 3466-3479. doi:10.1021/om201177y ISSN 0276-7333.
Betanzos-Lara, Soledad, Habtemariam, Abraha, Clarkson, Guy J. and Sadler, P. J. (2011) Organometallic cis-Dichlorido ruthenium(II) ammine complexes. European Journal of Inorganic Chemistry, Volume 2011 (Number 21). pp. 3257-3264. doi:10.1002/ejic.201100250 ISSN 1434-1948.
University of Warwick. Institute of Advanced Study (IAS)
Liu, Zhe , Romero-Canelón, Isolda, Qamar, Bushra, Hearn, Jessica M., Habtemariam, Abraha, Barry, Nicolas P. E., Pizarro, Ana M., Clarkson, Guy J. and Sadler, P. J. (2014) The potent oxidant anticancer activity of organoiridium catalysts. Angewandte Chemie International Edition, Volume 53 (Number 15). pp. 3941-3946. doi:10.1002/anie.201311161 ISSN 1433-7851.
Univerzita Palackého v Olomouci [Palacky University]
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Warwick Collaborative Postgraduate Research Scholarship (WCPRS)
Coverdale, James P. C., Sanchez-Cano, Carlos, Clarkson, Guy J., Soni, Rina, Wills, Martin and Sadler, P. J. (2015) Easy to synthesize, robust organo-osmium asymmetric transfer hydrogenation catalysts. Chemistry - A European Journal, 21 (22). pp. 8043-8046. doi:10.1002/chem.201500534 ISSN 0947-6539.
Warwick Collaborative Postgraduate Research Scholarships
Wootton, Christopher, Millett, Adam J., Lopez-Clavijo, Andrea F., Chiu, Cookson, Barrow, Mark P., Clarkson, Guy J., Sadler, P. J. and O'Connor, Peter B. (2019) Structural analysis of peptides modified with organo-iridium complexes, opportunities from multi-mode fragmentation. Analyst, 144 (5). pp. 1575-1581. doi:10.1039/C8AN02094A ISSN 0003-2654.
Wellcome Trust
Vernekar, Sanjeev Kumar V., Hallaq, Hasan Y., Clarkson, Guy J., Thompson, Andrew J., Silvestri, Linda, Lummis, Sarah C. R. and Lochner, Martin (2010) Toward biophysical probes for the 5-HT3 receptor : structure-activity relationship study of granisetron derivatives. Journal of Medicinal Chemistry, Vol.53 (No.5). pp. 2324-2328. doi:10.1021/jm901827x ISSN 0022-2623.
Wellcome Trust (London, England)
Guetzoyan, Lucie J., Spooner, Robert A. , Boal, Frédéric, Stephens, David J., Lord, Mike, Roberts, L. M. (Lynne M.) and Clarkson, Guy J. (2010) Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells. Molecular BioSystems, Vol.6 (No.10). pp. 2030-2038. doi:10.1039/c0mb00035c ISSN 1742-206X.
Spooner, Robert A., Watson, Peter, Smith, Daniel C., Boal, Frédéric, Amessou, Mohammed, Mohammed, Ludger, Clarkson, Guy J., Lord, Mike, Stephens, David J. and Roberts, L. M. (Lynne M.) (2008) The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Biochemical Journal, Vol.414 (No.3). pp. 471-484. doi:10.1042/BJ20080149 ISSN 0264-6021.
Yayasan Sarawak Tunku Abdul Rahman Sarawak Scholarship Scheme
Sebli, Cynthia Paul, Howson, Suzanne E., Clarkson, Guy J. and Scott, Peter (2010) fac-Specific syntheses of homochiral [Fe(NN ')(3)](2+) complexes (NN ' = pyridine keto-hydrazone); origins of the stereoselectivity. Dalton Transactions, Vol.39 (No.18). pp. 4447-4454. doi:10.1039/c000815j ISSN 1477-9226.
This list was generated on Thu Apr 25 05:31:42 2024 BST.