Thornalley, Paul J. and Rabbani, Naila. (2013) Detection of oxidized and glycated proteins in clinical samples using mass spectrometry — A user's perspective. Biochimica et Biophysica Acta (BBA) - General Subjects . ISSN 0304-4165 (In Press)

Rabbani, Naila, Adaikalakoteswari, Antonysunil, Rossing, Kasper, Rossing, Peter, Tarnow, Lise, Parving, Hans-Henrik and Thornalley, Paul J.. (2012) Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria. Amino Acids, Vol.42 (No.5). pp. 1627-1639. ISSN 0939-4451

Xue, Mingzhan, Rabbani, Naila, Momiji, Hiroshi, Imbasi, Precious, Anwar, M. Maqsud, Kitteringham, Neil, Park, B. Kevin, Souma, Tomokazu, Moriguchi, Takashi, Yamamoto, Masayuki and Thornalley, Paul J.. (2012) Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. The Biochemical journal, Vol.443 (No.1). pp. 213-22. ISSN 1470-8728

Rabbani, Naila and Thornalley, Paul J.. (2012) Glycation research in amino acids : a place to call home. Amino Acids, Vol.42 (No.4). pp. 1087-1096. ISSN 0939-4451

Rabbani, Naila and Thornalley, Paul J.. (2012) Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome. Amino Acids, Vol.42 (No.4). pp. 1133-1142. ISSN 0939-4451

Adaikalakoteswari, Antonysunil, Rabbani, Naila, Waspadji, Sarwono, Tjokroprawiro, Askandar, Kariadi, Sri H.K.S., Adam, John M.F. and Thornalley, Paul J.. (2012) Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia — link to renal status, glycemic control and vascular inflammation. Diabetes Research and Clinical Practice, Vol.95 (No.3). pp. 415-424. ISSN 0168-8227

Rabbani, Naila and Thornalley, Paul J.. (2012) Amino Acids Glycation Section. Amino Acids, Vol. 42 (No. 4). pp. 1085-1086. ISSN 0939-4451

Lopez-Clavijo, Andrea F., Barrow, Mark P., Rabbani, Naila, Thornalley, Paul J. and O’Connor, Peter B.. (2012) Determination of types and binding sites of advanced glycation end products for substance P. Analytical Chemistry, Vol.84 (No.24). pp. 10568-10575. ISSN 0003-2700

Larkin, James Robert, Zhang, F. (Fang), Godfrey, L. (Lisa), Molostvov, Guerman, Zehnder, Daniel, Rabbani, Naila and Thornalley, Paul J.. (2012) Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes. PLoS One, Vol.7 (No.12). Article no. e53175. ISSN 1932-6203

. (2012) Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nature Medicine, Vol.18 (No.6). pp. 926-933. ISSN 1078-8956

Perkins, Bruce A., Rabbani, Naila, Weston, Andrew J., Ficociello, Linda H., Adaikalakoteswari, Antonysunil, Niewczas, Monika, Warram, James, Krolewski, Andrzej S. and Thornalley, Paul J.. (2012) Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes. PLoS One, Vol.7 (No.4). e35655. ISSN 1932-6203

Rabbani, Naila and Thornalley, Paul J.. (2011) Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy. Diabetes, Obesity and Metabolism, Vol.13 (No.7). pp. 577-583. ISSN 1462-8902

Xue, Mingzhan, Rabbani, Naila and Thornalley, Paul J.. (2011) Glyoxalase in ageing. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 293-301. ISSN 1084-9521

Rabbani, Naila and Thornalley, Paul J.. (2011) Glyoxalase in diabetes, obesity and related disorders. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 309-317. ISSN 1084-9521

Thornalley, Paul J. and Rabbani, Naila. (2011) Glyoxalase in tumourigenesis and multidrug resistance. Seminars in Cell and Developmental Biology, Vol.22 (No.3). pp. 318-325. ISSN 1084-9521

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2011) Role of NRF2 and the antistress gene response in countering oxidative stress in diabetes mellitus. Clinical Chemistry and Laboratory Medicine, Vol.49 (Supp.1). S52-S52. ISSN 1434-6621

Rabbani, Naila and Thornalley, Paul J.. (2011) The glyoxalase system — from microbial metabolism, through ageing to human disease and multidrug resistance. Seminars in Cell and Developmental Biology, Vol.22 (No.3). p. 261. ISSN 1084-9521

Kurz, Alexander, Rabbani, Naila, Walter, Michael, Bonin, Michael, Thornalley, Paul J., Auburger, Georg and Gispert, Suzana. (2011) Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress. Cellular and Molecular Life Sciences, Vol.68 (No.4). pp. 721-733. ISSN 1420-682X

Thornalley, Paul J. and Rabbani, Naila. (2011) Protein damage in diabetes and uremia—identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect. Free Radical Research, Vol.45 (No.1). pp. 89-100. ISSN 1071-5762

Rabbani, Naila, Godfrey, L. (Lisa), Xue, Mingzhan, Shaheen, Fozia, Geoffrion, M., Milne, Ross and Thornalley, Paul J.. (2011) Glycation of LDL by methylglyoxal increases arterial atherogenicity : a possible contributor to increased risk of cardiovascular disease in diabetes. Diabetes, Vol.60 (No.7). pp. 1973-1980. ISSN 0012-1797

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2011) Methodologies for in-vitro and in-vivo activity of bioactive compounds. In: Terry, Leon A. (Leon Alexander), (ed.) Health-promoting properties of fruits and vegetables. Wallingford, Oxfordshire ; Cambridge, MA: CAB. ISBN 9781845935283

Thornalley, Paul J. and Rabbani, Naila (2011) Thiamine in diabetic renal disease - dietary insufficiency, renal washout, anti-stress gene response, therapeutic supplements, risk predictor and link to genetic susceptibility. In: Miyata, Toshio and Eckardt, Kai-Uwe and Nangaku, Masaomi, (eds.) Studies on renal disorders. Oxidative stress in applied basic research and clinical practice . New York: Humana Press, pp. 93-104. ISBN 9781607618577

Thornalley, Paul J., Waris, Sahar, Fleming, Thomas, Santarius, Thomas, Larkin, Sarah J., Winklhofer-Roob, Brigitte M., Stratton, Michael R. and Rabbani, Naila. (2010) Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance. Nucleic Acids Research, Vol.38 (No.16). pp. 5432-5442. ISSN 0305-1048

Thornalley, Paul J. and Rabbani, Naila (2010) Therapy: vitamin B6, B9 and B12 in diabetic nephropathy-beware. Nature Reviews Endocrinology, Vol.6 (No.9). pp. 477-478. ISSN 1759-5029

Karachalias, N., Babaei-Jadidi, R., Rabbani, Naila and Thornalley, Paul J.. (2010) Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes. Diabetologia, Vol.53 (No.7). pp. 1506-1516. ISSN 0012-186X

Ahmed, Usman, Rabbani, Naila, Filer, Andrew, Watts, Richard, Raza, Karim and Thornalley, Paul J. (2010) Changes in advanced glycation endproducts in synovial fluid in early resolving arthritis and early and established rheumatoid arthritis. In: Annual Meeting of the British Society Rheumatology/Spring Meeting of British Health Professional in Rheumatology, Birmingham, Englad, April 21-23, 2010. Published in: Rheumatology, Vol.49 (No.Suppl. 1). I161-I161.

Rabbani, Naila, Chittari, Madhu Varma, Bodmer, Charles W., Zehnder, Daniel, Ceriello, Antonio and Thornalley, Paul J.. (2010) Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin. Diabetes, Vol.59 (No.4). pp. 1038-1045. ISSN 0012-1797

Thornalley, Paul J., Babaei-Jadidi, R., Karachalias, N. and Rabbani, Naila (2010) Prevention of decline in glycaemic control in streptozotocin-induced diabetic rats by thiamine but not by Benfotiamine. Diabetic Medicine, Vol.27 (No.S1). p. 74. ISSN 0742-3071

Thornalley, Paul J. and Rabbani, Naila (2010) Dicarbonyls in cola drinks sweetened with sucrose or high fructose corn syrup. In: International Symposium on the Maillard Reaction, Palm Cove, Australia, 29-31 Aug 2009. Published in: Maillard Reaction: interface between aging, nutrition and metabolism pp. 158-163.

Thornalley, Paul J. and Rabbani, Naila (2010) Oxidation modification of proteins : an overview. In: Aldini, G. and Yeum, K. -J. and Niki, E. and Russell, R. M., (eds.) Biomarkers for antioxidant defense and oxidative damage : principles and practical applications. Ames, Iowa: Wiley-Blackwell, pp. 137-156. ISBN 9780813815350

Duran-Jimenez, Beatriz, Dobler, Darin, Moffatt, Sarah, Rabbani, Naila, Streuli, Charles H., Thornalley, Paul J., Tomlinson, David R. and Gardiner, Natalie J.. (2009) Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes. Diabetes, Vol.58 (No.12). pp. 2893-2903. ISSN 0012-1797

. (2009) C-elegans as model for the study of high glucose-mediated life span reduction. Diabetes, Vol.58 (No.11). pp. 2450-2456. ISSN 0012-1797

Rabbani, Naila, Chittari, M. V., Zehnder, Daniel, Ceriello, Antonio and Thornalley, Paul J. (2009) High dose metformin therapy reduces glycation and oxidative damage to apolipoprotein B100 and may decelerate atherosclerosis in patients with type 2 diabetes. In: 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Vienna, AUSTRIA, SEP 30-OCT 02, 2009. Published in: Diabetologia, Vol.52 (Suppl. 1). S498-S499.

Vanhorebeek, Ilse, Gunst, Jan, Ellger, Bjoern, Boussemaere, Magaly, Lerut, Evelyne, Debaveye, Yves, Rabbani, Naila, Thornalley, Paul J., Schetz, Miet and Van den Berghe, Greet (2009) Hyperglycemic kidney damage in an animal model of prolonged critical illness. In: 90th Annual Meeting of the Endocrine-Society, San Francisco, CA, June 15-18, 2008. Published in: Kidney International, Vol.76 (No.5). pp. 512-520.

Stoyanov, S. B., Fleming, T., Humpert, P. M., Sauer, S., Rabbani, Naila, Edelstein, D., Thornalley, Paul J., Reeh, P., Brownlee, M., Nawroth, P. P. and Bierhaus, A. (2009) Loss of glyoxalase-1 promotes hyperalgesia in early diabetic neuropathy. In: 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Vienna, Austria, September 30-October 02, 2009. Published in: Diabetologia, Vol.52 (Suppl.1). S444-S445.

Bechtold, Ulrike, Rabbani, Naila, Mullineaux, Philip M. and Thornalley, Paul J.. (2009) Quantitative measurement of specific biomarkers for protein oxidation, nitration and glycation in Arabidopsis leaves. Plant Journal, Vol.59 (No.4). pp. 661-671. ISSN 0960-7412

Thornalley, Paul J. and Rabbani, Naila. (2009) Highlights and hotspots of protein glycation in end-stage renal disease. Seminars in Dialysis, Vol.22 (No.4). pp. 400-404. ISSN 0894-0959

Thornalley, Paul J., Xue, Mingzhan and Rabbani, Naila (2009) Involvement of transcription factor nrf2 and antioxidant response element linked gene expression in countering oxidative stress in diabetes. In: 34th Congress of the Federation of European Biochemical Societies, Prague, Czech Republic, July 04-09, 2009. Published in: FEBS Journal, Vol.276 (Suppl. 1). pp. 79-80.

Rabbani, Naila, Alam, S. S., Riaz, S., Larkin, J. R., Akhtar, M. W., Shafi, T. and Thornalley, Paul J. (2009) Thiamine in diabetic nephropathy: a novel treatment modality? Reply to Alkhalaf A, Kleefstra N, Groenier KH et al. [letter]. Diabetologia, Vol.52 (No.6). pp. 1214-1216. ISSN 0012-186X

Vanhorebeek, Ilse, Ellger, Bjoern, De Vos, Rita, Boussemaere, Magaly, Debaveye, Yves, Vander Perre, Sarah, Rabbani, Naila, Thornalley, Paul J. and Van den Berghe, Greet. (2009) Tissue-specific glucose toxicity induces mitochondrial damage in a burn injury model of critical illness. Critical Care Medicine, Vol.37 (No.4). pp. 1355-1364. ISSN 0090-3493

Rabbani, Naila, Alam, S. S., Riaz, S., Larkin, J. R., Akhtar, M. W., Shafi, T. and Thornalley, Paul J.. (2009) High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: a randomised, double-blind placebo-controlled pilot study. Diabetologia, Vol.52 (No.2). pp. 208-212. ISSN 0012-186X

Rabbani, Naila and Thornalley, Paul J. (2009) Quantitation of markers of protein damage by glycation, oxidation, and nitration in peritoneal dialysis. In: 12th Congress of the International-Society-for-Peritoneal-Dialysis, Istanbul, Turkey, JUN 20-24, 2008. Published in: Peritoneal Dialysis International, Vol.29 (Suppl. 2). S51-S56.

Wendler, Alexandra, Irsch, Thorsten, Rabbani, Naila, Thornalley, Paul J. and Krauth-Siegel, R. Luise. (2009) Glyoxalase II does not support methylglyoxal detoxification but serves as a general trypanothione thioesterase in African trypanosomes. Molecular and Biochemical Parasitology, Vol.163 (No.1). pp. 19-27. ISSN 0166-6851

Ahmed, U., Rabbani, Naila, Costa, Matthew L., Watts, R. and Thornalley, Paul J. (2009) Increasing concentrations of proteolytic debris of glycated and oxidised proteins in patients with increasing severity of osteoarthritis. In: British Orthopaedic Research Society Annual Meeting, Newcastle-upon-Tyne, UK, 22-23 June 2009

Karachalias, N., Babaei-Jadidi, R., Rabbani, Naila and Thornalley, Paul J. (2009) Prevention of advanced glycation endproduct accumulation in renal glomeruli, retina and nerve in experimental diabetes by high dose thiamine and benfotiamine. In: Diabetes UK's Annual Professional Conference, SECC, Glasgow, UK, 11-13 March 2009 p. 70.

Xue, Mingzhan, Antonysunil, A., Rabbani, Naila and Thornalley, Paul J. (2009) Protein damage in the ageing process : advances in quantitation and the importance of enzymatic defences. In: Redox metabolism and longevity relationships in animals and plants. SEB experimental biology series, Vol.62 . New York ; Abingdon [England]: Taylor & Francis Group, pp. 227-265. ISBN 9780415419543

Yamada-Fowler, N., Godfrey, L. (Lisa), Thornalley, Paul J. and Rabbani, Naila (2009) Quantitation of the glycation-induced changes in HDL2 and HDL3 by liquid chromatography with tandem mass spectrometric detection. In: Diabetes UK's Annual Professional Conference, SECC, Glasgow, UK, 11-13 March 2009 p. 70.

Riaz, Samreen, Alam, Saadia Shahzad, Rabbani, Naila, Thornalley, Paul J. and Akhtar, Waheed (2009) Study of protein biomarker for diabetes type 2 and role of thiamien on their levels. In: 86th Annual Meeting of the Physiological Society of Japan, Kyoto, Japan, July 27–August 1, 2009. Published in: Journal of Physiological Sciences, Vol.59 (Suppl. 1). p. 506.

Thornalley, Paul J. and Rabbani, Naila (2009) Thiamine and benfotiamine therapy for the prevention of diabetic nephropathy. In: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options ; international expert workshop, Rome, Italy, Sep 2008. Published in: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options

Rabbani, Naila and Thornalley, Paul J. (2009) Thiamine deficiency and renal function in diabetes. In: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options ; international expert workshop, Rome, Italy, Sep 2008. Published in: Complications of diabetes mellitus pathophysiology and pathogenetically based treatment options pp. 18-25.

Xue, Mingzhan, Qian, Qingwen, Adaikalakoteswari, Antonysunil, Rabbani, Naila, Babaei-Jadidi, Roya and Thornalley, Paul J.. (2008) Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes, Volume 57 (Number 10). pp. 2809-2817. ISSN 0012-1797

Rabbani, Naila and Thornalley, Paul J. (2008) Dicarbonyls linked to damage in the powerhouse : glycation of mitochondrial proteins and oxidative stress. In: 3rd Intracellular Proteolysis Meeting, Canary Isl, Spain, Mar 05-07, 2008. Published in: Biochemical Society Transactions, Vol.36 (Pt.5). pp. 1045-1050.

Rabbani, Naila and Thornalley, Paul J. (2008) Increased protein damage by advanced glycation endproducts and oxidation adducts in low density lipoprotein of type 2 diabetic patients. In: 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S525-S525.

Xue, Mingzhan, Thornalley, Paul J. and Rabbani, Naila (2008) LDL glycated by methylglyoxal to physiological extent in vitro has increased binding of proteoglycan without impairment of LDL receptor binding. In: 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S299-S299.

Thornalley, Paul J., Qian, Q. and Rabbani, Naila (2008) Prevention of dicarbonyl stress induced by hyperglycaemia in microvascular endoethelial cells by sulforaphane. In: 43rd Annual Meeting of the European Association for the Study of Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S524-S524.

Adaikalakoteswari, A., Perkins, B., Krolewski, A. S., Rabbani, Naila and Thornalley, Paul J. (2008) Thiamine status and risk of early renal function decline in type 1 diabetic patients. In: 43rd General Assembly of the European Association for the Study of Diabetes, Amsterdam, 20 September 2007. Published in: Diabetologia, Vol.51 (Suppl.1). S98-S98.

Fleming, Thomas, Rabbani, Naila and Thornalley, Paul J.. (2008) Preparation of nucleotide advanced glycation endproducts - Imidazopurinone adducts formed by glycation of deoxyguanosine with glyoxal and methylglyoxal. New York Academy of Sciences. Annals, Volume 1126 . pp. 280-282. ISSN 0077-8923

Ahmed, Usman, Dobler, Darin, Larkin, Sarah J., Rabbani, Naila and Thornalley, Paul J. (2008) Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro. In: 9th International Symposium on the Maillard Reaction, Munich, Germany, Sep, 2007. Published in: New York Academy of Sciences. Annals, Vol.1126 pp. 262-264.

Rabbani, Naila and Thornalley, Paul J. (2008) The dicarbonyl proteome - proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease. In: 9th International Symposium on the Maillard Reaction, Munich, Germany, Sep, 2007. Published in: Annals of the New York Academy of Sciences, Vol.1126 pp. 124-127.

Rabbani, Naila and Thornalley, Paul J. (2008) Assay of 3-nitrotyrosine in tissues and body fluids by liquid chromatography with tandem mass spectrometric detection. Methods in Enzymology, Vol.440 . pp. 337-359. ISSN 0076-6879

Perkins, B., Rabbani, Naila, Weston, A., Adaikalakoteswari, A., Ficociello, L., Warram, J., Krolewski, A. S. and Thornalley, Paul J. (2008) Early renal function decline in type 1 diabetes is associated with excess urinary excretion of markers of protein damage. Diabetes, Vol.57 . A210-A210. ISSN 0012-1797

Rabbani, Naila, Sebekova, K., Sebekova, K., Heidland, A. and Thornalley, Paul J.. (2007) Accumulation of free adduct glycation, oxidation, and nitration products follows acute loss of renal function. Kidney International, Vol.72 (No.9). pp. 1113-1121. ISSN 0085-2538

Yao, Dachun, Taguchi, Tetsuya, Matsumura, Takeshi, Pestell, Richard, Edelstein, Diane, Giardino, Ida, Suske, Guntram, Rabbani, Naila, Thornalley, Paul J., Sarthy, Vijay P., Hammes, Hans-Peter and Brownlee, Michael. (2007) High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. Journal of Biological Chemistry, Vol.282 (No.42). pp. 31038-31045. ISSN 0021-9258

Thornalley, Paul J., Babaei-Jadidi, R., Al Ali, H., Rabbani, Naila, Antonysunil, A., Larkin, J. R., Ahmed, A., Rayman, G. and Bodmer, C. W.. (2007) High prevalence of low plasma thiamine concentration in diabetes linked to a marker of vascular disease. Diabetologia, Vol.50 (No.10). pp. 2164-2170. ISSN 0012-186X

Morcos, M., Morcos, M., Sayed, A., Pfisterer, F., Kukudov, G., El Baki, R. Abd, Rabbani, Naila, Du, X., Hutter, H., Thornalley, Paul J., Baynes, J. and Thorpe, S. (2007) Life extension in Caenorhabditis elegans by overexpression of Glyoxalase I - A mechanistic integration of protein damage by glycation, oxidation and nitratio. In: Annual Main Meeting of the Society for Experimental Biology, Glasgow, Scotland, March 31 - April 4, 2007. Published in: Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology, Vol.146 (No.4 Supplement). S59-S59.