2018

Raza, Shan-e-Ahmed, Cheung, Linda, Shaban, Muhammad, Graham, Simon, Epstein, David M., Pelengaris, Stella, Khan, Michael and Rajpoot, Nasir M. (2018) Micro-Net : a unified model for segmentation of various objects in microscopy images. Medical Image Analysis, 52 . pp. 160-173. doi:10.1016/j.media.2018.12.003 (In Press)

2015

RUTHERFORD-2 Investigators (Including: Raal, Frederick J, Stein, Evan A, Dufour, Robert, Turner, Traci, Civeira, Fernando, Burgess, Lesley, Langslet, Gisle, Scott, Russell, Olsson, Anders G, Sullivan, David, Hovingh, G Kees, Cariou, Bertrand, Gouni-Berthold, Ioanna, Somaratne, Ransi, Bridges, Ian, Scott, Rob, Wasserman, Scott M and Gaudet, Daniel). (2015) PCSK9 inhibition with evolocumab (AMG 145) in heterozygous familial hypercholesterolaemia (RUTHERFORD-2) : a randomised, double-blind, placebo-controlled trial. The Lancet, 385 (9965). pp. 331-340. doi:10.1016/S0140-6736(14)61399-4

2014

The Guideline Development Group (Including: Rabar, S., Harker, M., O'Flynn, N. and Wierzbicki, A. S.). (2014) Lipid modification and cardiovascular risk assessment for the primary and secondary prevention of cardiovascular disease : summary of updated NICE guidance. BMJ, 349 (12). g4356. doi:10.1136/bmj.g4356

Khan, Adnan M., Raza, Shan-e-Ahmed, Khan, Michael and Rajpoot, Nasir M. (2014) Cell phenotyping in multi-tag fluorescent bioimages. Neurocomputing , Volume 134 . pp. 254-261. doi:10.1016/j.neucom.2013.08.043

Kovacheva, Violeta N., Khan, Adnan M., Khan, Michael, Epstein, D. B. A. and Rajpoot, Nasir M. (Nasir Mahmood) (2014) DiSWOP : a novel measure for cell-level protein network analysis in localized proteomics image data. Bioinformatics, Volume 30 (Number 3). pp. 420-427. doi:10.1093/bioinformatics/btt676

Khan, Michael, Taibjee, S. M., Poole, C. J. and Gach, J. E. (2014) Bullous reaction at docetaxel infusion site. Clinical and Experimental Dermatology, Volume 39 (Number 1). pp. 58-60. doi:10.1111/ced.12182

Schultheis, B., Strumberg, D., Santel, A., Vank, C., Gebhardt, F., Keil, O., Lange, C., Giese, K., Kaufmann, J., Khan, Michael and Drevs, J. (2014) First-in-human phase I study of the liposomal RNA interference therapeutic Atu027 in patients with advanced solid tumors. Journal of Clinical Oncology, 32 (36). pp. 4141-4148. JCO.2013.55.0376. doi:10.1200/JCO.2013.55.0376

2013

Pelengaris, Stella and Khan, Michael, eds. (2013) The molecular biology of cancer : a bridge from bed to bedside 2nd edition. Oxford: Wiley-Blackwell Publishing Ltd..

2012

Kolling, J., Langenkamper, D., Abouna, Sylvie, Khan, Michael and Nattkemper, T. W. (2012) WHIDE - a web tool for visual data mining colocation patterns in multivariate bioimages. Bioinformatics, 28 (8). pp. 1143-1150. doi:10.1093/bioinformatics/bts104

Raza, Shan-e-Ahmed, Humayun, Ahmad, Abouna, Sylvie, Nattkemper, Tim W., Epstein, D. B. A., Khan, Michael and Rajpoot, Nasir M. (Nasir Mahmood) (2012) RAMTaB : robust alignment of multi-tag bioimages. PLoS One, Vol.7 (No.2). e30894. doi:10.1371/journal.pone.0030894

Kuse, Manohar, Wang, Yi-Fang, Kalasannavar, V, Khan, Michael and Rajpoot, Nasir M. (Nasir Mahmood) (2012) Local isotropic phase symmetry measure for detection of beta cells and lymphocytes. Journal of Pathology Informatics, Vol.2 (No.2). doi:10.4103/2153-3539.92028

Wang, Yi-Fang, Khan, Michael and Berg, Hugo van den (2012) Interaction of fast and slow dynamics in endocrine control systems with an application to β-cell dynamics. Mathematical Biosciences, Vol.235 (No.1). pp. 8-18. doi:10.1016/j.mbs.2011.10.003

Hattersley, John G., Möhlig, Matthias, Roden, Michael, Dr., Arafat, Ayman M., Loeffelholz, Christian von, Nowotny, Peter, Machann, Jürgen, Hierholzer, Johannes, Osterhoff, Martin, Khan, Michael, Pfeiffer, Andreas F. H. and Weickert, Martin O. (2012) Quantifying the improvement of surrogate indices of hepatic insulin resistance using complex measurement techniques. PLoS ONE, Vol.7 (No.6). Article no. e39029. doi:10.1371/journal.pone.0039029

Zhou, Luxian, Pelengaris, Stella, Abouna, Sylvie, Young, James, Epstein, D. B. A., Herold, Julia, Nattkemper, Tim W., Nakhai, Hassan and Khan, Michael (2012) Re-expression of IGF-II is important for beta cell regeneration in adult mice. PLoS ONE, Vol.7 (No.9). e43623. doi:10.1371/journal.pone.0043623

Kolling, J., Langenkamper, D., Abouna, S., Khan, Michael and Nattkemper, Tim W. (2012) WHIDE--a web tool for visual data mining colocation patterns in multivariate bioimages. Bioinformatics, Vol.28 (No.8). pp. 1143-1150. doi:10.1093/bioinformatics/bts104

Tarabra, Elena, Pelengaris, Stella and Khan, Michael (2012) A simple matter of life and death : the trials of postnatal beta-cell mass regulation. International Journal of Endocrinology, Vol.2012 . Article no. 516718. doi:10.1155/2012/516718

2011

Robson, Samuel Charles, Ward, Lesley (Lesley A.), Brown, Helen (Helen E.), Turner, Heather, Hunter, Ewan, Pelengaris, Stella and Khan, Michael (2011) Deciphering c-MYC-regulated genes in two distinct tissues. BMC Genomics, Vol.12 (No.9(Sept)). Article No.476. doi:10.1186/1471-2164-12-476

Humayun, A., Raza, Shan-e-Ahmed, Waddington, C., Abouna, Sylvie, Khan, Michael and Rajpoot, Nasir M. (Nasir Mahmood) (2011) A novel framework for molecular co-expression pattern analysis in multi-channel toponome fluorescence images. In: MIAAB 2011 (Microscopic Image Analysis with Applications in Biology), Heidelberg, Germany, 2 Sep 2011. Published in: Proceedings of the 2011 Microscopic Image Analysis with Applications in Biology (Submitted)

Loyek, Christian, Rajpoot, Nasir M. (Nasir Mahmood), Khan, Michael and Nattkemper, Tim W. (2011) BioIMAX : a web 2.0 approach for easy exploratory and collaborative access to multivariate bioimage data. BMC Bioinformatics, Vol.12 (No.1). Article 297. doi:10.1186/1471-2105-12-297

Langenkämper, Daniel, Kölling, Jan, Abouna, Sylvie, Khan, Michael, Niehaus, Karsten and Nattkemper, Tim W. (2011) TICAL - a web-tool for multivariate image clustering and data topology preserving visualization. In: MIAAB 2011 (Microscopic Image Analysis with Applications in Biology), Heidelberg, Germany, 2 Sep 2011. Published in: Proceedings of the 2011 Microscopic Image Analysis with Applications in Biology pp. 1-5.

2010

Zervou, S., Wang, Y. -F., Laiho, A., Gyenesei, A., Kytomaki, L., Hermann, R., Abouna, Sylvie, Epstein, D., Pelengaris, Stella and Khan, Michael (2010) Short-term hyperglycaemia causes non-reversible changes in arterial gene expression in a fully 'switchable' in vivo mouse model of diabetes. Diabetologia, Vol.53 (No.12). pp. 2676-2687. doi:10.1007/s00125-010-1887-5

Bhattacharya, Sayantan, Mathew, George, Ruban, Ernie, Epstein, D. B. A., Krusche, Andreas, Hillert, Reyk, Schubert, Walter and Khan, Michael (2010) Toponome imaging system in situ protein network mapping in normal and cancerous colon from the same patient reveals more than five-thousand cancer specific protein clusters and their subcellular annotation by using a three symbol code. Journal of Proteome Research, Vol.9 (No.12). pp. 6112-6125. doi:10.1021/pr100157p

Herold, Julia, Zhou, Luxian, Abouna, Sylvie, Pelengaris, Stella, Epstein, D. B. A., Khan, Michael and Nattkemper, Tim W. (2010) Integrating semantic annotation and information visualization for the analysis of multichannel fluorescence micrographs from pancreatic tissue. In: 8th IEEE International Conference on Bioinformatics and Bioengineering, Athens, Greece, October 08-10, 2008. Published in: Computerized Medical Imaging and Graphics, No.34 (No.6). pp. 446-452. ISSN 0895-6111. doi:10.1016/j.compmedimag.2009.10.004

Abouna, Sylvie, Old, R. W., Pelengaris, Stella, Epstein, D. B. A., Ifandi, Vasiliki, Sweeney, Ian and Khan, Michael (2010) Non-β-cell progenitors of β-cells in pregnant mice. Organogenesis, Volume 6 (Number 2). pp. 125-133. doi:10.4161/org.6.2.10374

Robson, Sam, Pukonen, Inga, Abouna, Sylvie, Pelengaris, Stella and Khan, Michael (2010) c-Myc and Downstream Targets in the Pathogenesis and Treatment of Cancer. In: Frontiers in Anti-Cancer Drug Discovery. Frontiers in Anti-Cancer Drug Discovery, Vol.1 . Netherlands: Bentham Science Publishers Ltd, pp. 340-379. ISBN 978-1-60805-161-8

Cheung, Linda, Zervou, Sevasti I., Mattsson, Göran, Abouna, Sylvie, Zhou, Luxian, Ifandi, Vasiliki, Pelengaris, Stella and Khan, Michael (2010) c-Myc directly induces both impaired insulin secretion and loss of β-cell mass, independently of hyperglycemia in vivo. Islets, Volume 2 (Number 1). pp. 37-45. doi:10.4161/isl.2.1.10196

2009

Zhou, Luxian, Pelengaris, Stella, Abouna, Sylvie, Young, J., Epstein, D. B. A. and Khan, Michael (2009) IGF-II reexpression in adult mice is essential for beta cell regeneration in vivo. In: 45th Annual Meeting of the European Association for the Study of Diabetes, Vienna, Austria, September 30-October 02, 2009. Published in: Diabetologia, Vol.52 (Suppl. 1). S23-S23. ISSN 0012-186X. doi:10.1007/s00125-009-1445-1

Abouna, Sylvie, Old, R. W., Pelengaris, Stella, Epstein, D. B. A., Ifandi, V., Sweeney, I. and Khan, Michael (2009) Non beta cell progenitors of beta cells in pregnant mice. In: 45th Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Vienna, Austria, SEP 30-OCT 02, 2009. Published in: Diabetologia, Vol.52 (Suppl. 1). S185-S185. ISSN 0012-186X.

Bhattacharya, S., Mathew, G., Jayne, D. G., Pelengaris, Stella and Khan, Michael (2009) 15-Lipoxygenase-1 in colorectal cancer: a review. Tumor Biology, Vol.30 (No.4). pp. 185-199. doi:10.1159/000236864

2008

Pascal, Severine M. A., Guiot, Yves, Pelengaris, Stella, Khan, Michael and Jonas, Jean-Christophe (2008) Effects of c-MYC activation on glucose stimulus-secretion coupling events in mouse pancreatic islets. American Journal of Physiology: Endocrinology and Metabolism, Vol.295 (No.1). E92-E102. doi:10.1152/ajpendo.90235.2008

Pascal, S. M. A., Pelengaris, Stella, Khan, Michael and Jonas, J. C. (2008) Effets d’une activation contrôlée du facteur de transcription c-MYC sur la fonction et la survie des cellules pancréatiques de souris. In: Congrès annuel de l'Alfediam Bruxelles, Brussels, Belgium, 25-28 Mar, 2008. Published in: Diabetes & Metabolism, Vol.34 (Suppl. 3). H33. ISSN 1262-3636. doi:10.1016/S1262-3636(08)72884-2

Herold, Julia, Abouna, Sylvie, Zhou, Luxian, Pelengaris, Stella, Epstein, D. B. A., Khan, Michael and Nattkemper, Tim W. (2008) A machine learning based system for multichannel fluorescence analysis in pancreatic tissue bioimages. In: 8th IEEE International Conference on Bioinformatics and Bioengineering, Athens, Greece, October 08-10, 2008. Published in: Proceedings of the 8th IEEE International Conference on Bioinformatics and Bioengineering, Vol.1-2 pp. 881-886. doi:10.1109/BIBE.2008.4696798

2007

Pascal, S. M. A., Pelengaris, Stella, Khan, Michael and Jonas, J.-C. (2007) Effects of controlled c-MYC activation on mouse pancreatic beta cell survival and function. In: 43rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.50 (Suppl. 1). S183-S183. ISSN 0012-186X. doi:10.1007/s00125-007-0809-7

Zervou, S., Pelengaris, Stella, Epstein, D. and Khan, Michael (2007) Reversible and irreversible changes in arterial gene expression after initiation of hyperglycaemia in plus -MYCER mice in vivo. In: 43rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes, Amsterdam, Netherlands, Sep 18-21, 2007. Published in: Diabetologia, Vol.50 (Suppl. 1). S90-S90. ISSN 0012-186X.

2006

Robson, Samuel Charles, Pelengaris, Stella and Khan, Michael (2006) c-Myc and downstream targets in the pathogenesis and treatment of cancer. Recent Patents on Anti-Cancer Drug Discovery, Vol.1 (No.3). pp. 305-326. doi:10.2174/157489206778776934

2004

Pelengaris, Stella, Abouna, Sylvie, Cheung, Linda, Ifandi, Vasiliki, Zervou, Sevasti I. and Khan, Michael (2004) Brief inactivation of c-Myc is not sufficient for sustained regression of c-Myc-induced tumours of pancreatic islets and skin epidermis. BMC Biology, Vol.2 (No.26). doi:10.1186/1741-7007-2-26