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Jump to: Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | Centre for BioSystems Genomics (CBSG) | Centre national de la recherche scientifique (France) (CNRS) | China. Jiao yu bu (China. Ministry of Education) | Engineering and Physical Sciences Research Council (EPSRC) | Erasmus Mundus (Program) | European Commission (EC) | European Research Council (ERC) | Fondation pour la recherche médicale (FRM) | Fonds FCAR (Québec) | Fonds de la recherche en santé du Québec (FRSQ) | Guo jia zi ran ke xue ji jin wei yuan hui (China) (NSFC) | Kurdistān (Iraq). Ḧikûmetî Herêmî Kurdistan-ʻÊraq [Kurdistan Regional Government] | Medical Research Council (Great Britain) (MRC) | National Health and Medical Research Council (Australia) (NHMRC) | National Institutes of Health. National Institute of Allergy and Infectious Diseases (U.S.) (NIH NIAID) | National Science Foundation (U.S.) (NSF) | Natural Environment Research Council (Great Britain) (NERC) | Natural Sciences and Engineering Research Council Canada (NSERC) | Natural Sciences and Engineering Research Council of Canada | Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Netherlands Organisation for Scientific Research] (NWO) | Networks of Centres of Excellence (Canada) | New South Wales Government | Quebecois de la Recherche sur la Nature et les Technologies | Royal Society (Great Britain) | Shanghai Municipal Scientific Committee | Sixth Framework Programme (European Commission) (FP6) | Syngenta Seeds Ltd. | Technology Strategy Board (Great Britain) | Tuck Foundation | University of Warwick | University of Warwick. Innovative Materials Research Centre | Warwick Innovative Manufacturing Research Centre (IMRC) | Wellcome Trust (London, England)
Number of items: 70.
Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Eyice, Özge, Myronova, Natalia, Pol, Arjan, Carrion, Ornella, Todd, Jonathan, Smith, Tom J., Gurman, Stephen J., Cuthbertson, Adam, Mazard, Sophie, Mennink-Kersten, Monique A. S. H. , Bugg, Tim, Andersson, K. Kristoffer, Johnston, Andrew W. B., Op Den Camp, Huub J. M. and Schäfer, Hendrik (2018) Bacterial SBP56 identified as a Cu-dependent methanethiol oxidase widely distributed in the biosphere. ISME Journal, 12 (1). 145-160 . doi:10.1038/ismej.2017.148 ISSN 1751-7362.
Millar, Robert, Rahmanpour, Rahman, Wei Jia Yuan, Eugenie, White, Catharine and Bugg, Tim (2017) Esterase EstK from Pseudomonas putida mt-2 : an enantioselective acetylesterase with activity for deacetylation of xylan and poly(vinylacetate). Biotechnology and Applied Biochemistry, 64 (6). pp. 803-809. ISSN 0885-4513.
Rahmanpour, Rahman, King, Lloyd D. W and Bugg, Tim (2017) Identification of an extracellular bacterial flavoenzyme that can prevent re-polymerisation of lignin fragments. Biochemical and Biophysical Research Communications, 482 (1). pp. 57-61. doi:10.1016/j.bbrc.2016.10.144 ISSN 0006-291X.
Awan, Sajjad Zahoor, Chandler, Jake Owen, Harrison, Peter J., Sergeant, Martin J., Bugg, Tim and Thompson, Andrew David (2017) Promotion of germination using hydroxamic acid inhibitors of 9-cis-epoxycarotenoid dioxygenase. Frontiers in Plant Science, 8 . 357. doi:10.3389/fpls.2017.00357 ISSN 1664-462X.
Lancefield, Christopher S., Rashid, Goran M. M., Bouxin, Florent, Wasak, Agata, Tu, Wei-Chien, Hallett, Jason P., Zein, Sharif, Rodriguez, Jaime, Jackson, S. David, Westwood, Nicholas J. and Bugg, Timothy D. H. (2016) An investigation of the chemocatalytic and biocatalytic valorisation of a range of different lignin preparations : the importance of β-O-4 content. ACS Sustainable Chemistry & Engineering . doi:10.1021/acssuschemeng.6b01855 ISSN 2168-0485.
Rahmanpour, Rahman , Rea, Dean, Jamshidi, Shirin, Fülöp, Vilmos and Bugg, Tim (2016) Structure of thermobifida fusca DyP-type peroxidase and activity towards kraft lignin and lignin model compounds. Archives of Biochemistry and Biophysics, 594 . pp. 54-60. doi:10.1016/j.abb.2016.02.019 ISSN 0003-9861.
Harrison, Peter J., Newgas, Sophie A., Descombes, Flora, Shepherd, Sarah A., Thompson, Andrew J. and Bugg, Tim (2015) Biochemical characterization and selective inhibition of β-carotenecis-transisomerase D27 and carotenoid cleavage dioxygenase CCD8 on the strigolactone biosynthetic pathway. FEBS Journal . doi:10.1111/febs.13400 ISSN 1742-464X.
Rashid, Goran M. M., Taylor, Charles R. (Charles Robert), Liu, Yangqingxu, Zhang, Xiaoyang, Rea, Dean, Fülöp, Vilmos and Bugg, Tim (2015) Identification of manganese superoxide dismutase from Sphingobacterium sp. T2 as a novel bacterial enzyme for lignin oxidation. ACS chemical biology, 10 (10). pp. 2286-2294. doi:10.1021/acschembio.5b00298 ISSN 1554-8929.
Roberts, Joseph N., Singh, Rahul, Grigg, Jason C., Murphy, Michael E. P., Bugg, Tim and Eltis, Lindsay D. (2011) Characterization of dye-decolorizing peroxidases from Rhodococcus jostii RHA1. Biochemistry, Vol.50 (No.23). pp. 5108-5119. doi:10.1021/bi200427h ISSN 0006-2960.
Bugg, Tim, Ahmad, Mark, Hardiman, Elizabeth M. and Rahmanpour, Rahman (2011) Pathways for degradation of lignin in bacteria and fungi. Natural Product Reports, Vol.28 (No.12). pp. 1883-1896. doi:10.1039/c1np00042j ISSN 0265-0568.
Bugg, Tim, Ahmad, Mark, Hardiman, Elizabeth M. and Singh, Rahul (2011) The emerging role for bacteria in lignin degradation and bio-product formation. Current Opinion in Biotechnology, Vol.22 (No.3). pp. 394-400. doi:10.1016/j.copbio.2010.10.009 ISSN 0958-1669.
López-Ráez, Juan A., Kohlen, Wouter, Charnikhova, Tatsiana, Mulder, Patrick, Undas, Anna K., Sergeant, Martin J., Verstappen, Francel, Bugg, Tim, Thompson, Andrew J., Ruyter-Spira, Carolien and Bouwmeester, Harro (2010) Does abscisic acid affect strigolactone biosynthesis? New Phytologist, Vol.87 (No.2). pp. 343-354. doi:10.1111/j.1469-8137.2010.03291.x ISSN 0028-646X.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
Sergeant, Martin J., Li, J.J., Fox, C., Brookbank, N., Rea, Dean, Bugg, Tim and Thompson, Andrew J. (2009) Selective inhibition of carotenoid cleavage dioxygenases : phenotypic effects on shoot branching. Journal of Biological Chemistry, Vol.284 (No.8). pp. 5257-5264. doi:10.1074/jbc.M805453200 ISSN 0021-9258.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
Rea, Dean, Hovington, Rebecca, Rakus, John F., Gerlt, John A., Fülöp, Vilmos, Bugg, Tim and Roper, David I. (2008) Crystal structure and functional assignment of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12. Biochemistry, Vol.47 (No.38). pp. 9955-9965. doi:10.1021/bi800943g ISSN 0006-2960.
Dodd, Charlotte E., Johnson, Benjamin R. G., Jeuken, Lars J. C., Bugg, Tim, Bushby, Richard J. and Evans, Stephen D. (2008) Native E. coli inner membrane incorporation in solid-supported lipid bilayer membranes. Biointerphases, Vol.3 (No.2). FA59-FA67. doi:10.1116/1.2896113 ISSN 1559-4106.
Lam, Wai-Ho, Rychli, Kathrin and Bugg, Tim (2008) Identification of a novel β-replacement reaction in the biosynthesis of 2,3-diaminobutyric acid in peptidylnucleoside mureidomycin A. Organic & Biomolecular Chemistry, Vol.6 (No.11). pp. 1912-1917. doi:10.1039/b802585a ISSN 1477-0520.
Centre for BioSystems Genomics (CBSG)
López-Ráez, Juan A., Kohlen, Wouter, Charnikhova, Tatsiana, Mulder, Patrick, Undas, Anna K., Sergeant, Martin J., Verstappen, Francel, Bugg, Tim, Thompson, Andrew J., Ruyter-Spira, Carolien and Bouwmeester, Harro (2010) Does abscisic acid affect strigolactone biosynthesis? New Phytologist, Vol.87 (No.2). pp. 343-354. doi:10.1111/j.1469-8137.2010.03291.x ISSN 0028-646X.
Centre national de la recherche scientifique (France) (CNRS)
Bouhss, Ahmed, Trunkfield, Amy E., Bugg, Tim and Mengin-Lecreulx, Dominique (2008) The biosynthesis of peptidoglycan lipid-linked intermediates. FEMS Microbiology Reviews, Vol.32 (No.2). pp. 208-233. ISSN 0168-6445 doi:10.1111/j.1574-6976.2007.00089.x
China. Jiao yu bu (China. Ministry of Education)
Xu, Xiu-Hua, Trunkfield, Amy E., Bugg, Tim and Qing, Feng-Ling (2008) Synthesis of gem-difluorinated nucleoside analogues of the liposidomycins and evaluation as MraY inhibitors. Organic & Biomolecular Chemistry, Vol.6 (No.1). pp. 157-161. doi:10.1039/b713068f ISSN 1477-0520.
Engineering and Physical Sciences Research Council (EPSRC)
Hattersley, John G., Pérez-Velázquez, J., Chappell, M. J. (Michael J.), Bearup, Daniel James, Roper, David I., Dowson, Christopher G., Bugg, Tim and Evans, Neil D. (2011) Indistinguishability and identifiability of kinetic models for the MurC reaction in peptidoglycan biosynthesis. Computer Methods and Programs in Biomedicine, Vol.104 (No.2). pp. 70-80. doi:10.1016/j.cmpb.2010.07.009 ISSN 01692607.
Trunkfield, Amy E., Gurcha, Sudagar S., Besra, Gurdyal S. and Bugg, Tim (2010) Inhibition of escherichia coli glycosyltransferase MurG and mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics. Bioorganic & Medicinal Chemistry, Vol.18 (No.7). pp. 2651-2663. doi:10.1016/j.bmc.2010.02.026 ISSN 0968-0896.
Erasmus Mundus (Program)
Brivio, Michela, Schlosrich, Janne, Ahmad, Mark, Tolond, Caroline and Bugg, Tim (2009) Investigation of acid-base catalysis in the extradiol and intradiol catechol dioxygenase reactions using a broad specificity mutant enzyme and model chemistry. Organic & Biomolecular Chemistry, Vol.7 (No.7). pp. 1368-1373. doi:10.1039/b821559f ISSN 1477-0520.
Lam, Wai-Ho, Rychli, Kathrin and Bugg, Tim (2008) Identification of a novel β-replacement reaction in the biosynthesis of 2,3-diaminobutyric acid in peptidylnucleoside mureidomycin A. Organic & Biomolecular Chemistry, Vol.6 (No.11). pp. 1912-1917. doi:10.1039/b802585a ISSN 1477-0520.
European Commission (EC)
López-Ráez, Juan A., Kohlen, Wouter, Charnikhova, Tatsiana, Mulder, Patrick, Undas, Anna K., Sergeant, Martin J., Verstappen, Francel, Bugg, Tim, Thompson, Andrew J., Ruyter-Spira, Carolien and Bouwmeester, Harro (2010) Does abscisic acid affect strigolactone biosynthesis? New Phytologist, Vol.87 (No.2). pp. 343-354. doi:10.1111/j.1469-8137.2010.03291.x ISSN 0028-646X.
European Research Council (ERC)
Eyice, Özge, Myronova, Natalia, Pol, Arjan, Carrion, Ornella, Todd, Jonathan, Smith, Tom J., Gurman, Stephen J., Cuthbertson, Adam, Mazard, Sophie, Mennink-Kersten, Monique A. S. H. , Bugg, Tim, Andersson, K. Kristoffer, Johnston, Andrew W. B., Op Den Camp, Huub J. M. and Schäfer, Hendrik (2018) Bacterial SBP56 identified as a Cu-dependent methanethiol oxidase widely distributed in the biosphere. ISME Journal, 12 (1). 145-160 . doi:10.1038/ismej.2017.148 ISSN 1751-7362.
Fondation pour la recherche médicale (FRM)
Mainardi, Jean-Luc, Villet, Regis, Bugg, Tim, Mayer, Claudine and Arthur, Michel (2008) Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria. FEMS Microbiology Reviews, Vol.32 (No.2). pp. 386-408. ISSN 0168-6445 doi:10.1111/j.1574-6976.2007.00097.x
Fonds FCAR (Québec)
Paradis-Bleau , Catherine, Lloyd, Adrian, Sanschagrin, François, Clark, Tom, Blewett, Ann, Bugg, Tim and Levesque, Roger C. (2008) Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. BMC Biochemistry, Vol.9 (No.33). doi:10.1186/1471-2091-9-33 ISSN 1471-2091.
Fonds de la recherche en santé du Québec (FRSQ)
Paradis-Bleau , Catherine, Lloyd, Adrian, Sanschagrin, François, Clark, Tom, Blewett, Ann, Bugg, Tim and Levesque, Roger C. (2008) Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. BMC Biochemistry, Vol.9 (No.33). doi:10.1186/1471-2091-9-33 ISSN 1471-2091.
Guo jia zi ran ke xue ji jin wei yuan hui (China) (NSFC)
Xu, Xiu-Hua, Trunkfield, Amy E., Bugg, Tim and Qing, Feng-Ling (2008) Synthesis of gem-difluorinated nucleoside analogues of the liposidomycins and evaluation as MraY inhibitors. Organic & Biomolecular Chemistry, Vol.6 (No.1). pp. 157-161. doi:10.1039/b713068f ISSN 1477-0520.
Kurdistān (Iraq). Ḧikûmetî Herêmî Kurdistan-ʻÊraq [Kurdistan Regional Government]
Rashid, Goran M. M., Taylor, Charles R. (Charles Robert), Liu, Yangqingxu, Zhang, Xiaoyang, Rea, Dean, Fülöp, Vilmos and Bugg, Tim (2015) Identification of manganese superoxide dismutase from Sphingobacterium sp. T2 as a novel bacterial enzyme for lignin oxidation. ACS chemical biology, 10 (10). pp. 2286-2294. doi:10.1021/acschembio.5b00298 ISSN 1554-8929.
Medical Research Council (Great Britain) (MRC)
Bugg, Tim, Rodolis, Maria T., Mihalyi, Agnes and Jamshidi, Shirin (2016) Inhibition of phospho-MurNAc-pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage <phi>X174 lysis protein E, and cationic antibacterial peptides. Bioorganic and Medicinal Chemistry . doi:10.1016/j.bmc.2016.03.018 ISSN 0968-0896.
Trunkfield, Amy E., Gurcha, Sudagar S., Besra, Gurdyal S. and Bugg, Tim (2010) Inhibition of escherichia coli glycosyltransferase MurG and mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics. Bioorganic & Medicinal Chemistry, Vol.18 (No.7). pp. 2651-2663. doi:10.1016/j.bmc.2010.02.026 ISSN 0968-0896.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
National Health and Medical Research Council (Australia) (NHMRC)
Tran, Anh T., Watson, Emma E., Pujari, Venugopal, Conroy, Trent, Dowman, Luke J., Giltrap, Andrew M., Pang, Angel, Wong, Weng-Ruh, Linington, Roger G., Saunders, Jessica, Charman, Susan A., West, Nicholas P., Bugg, Tim, Tod, Julie, Dowson, Christopher G., Roper, David I., Crick, Dean C., Britton, Warwick J. and Payne, Richard J. (2017) Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nature Communications, 8 . 14414 . doi:10.1038/ncomms14414 ISSN 2041-1723.
National Institutes of Health. National Institute of Allergy and Infectious Diseases (U.S.) (NIH NIAID)
Tran, Anh T., Watson, Emma E., Pujari, Venugopal, Conroy, Trent, Dowman, Luke J., Giltrap, Andrew M., Pang, Angel, Wong, Weng-Ruh, Linington, Roger G., Saunders, Jessica, Charman, Susan A., West, Nicholas P., Bugg, Tim, Tod, Julie, Dowson, Christopher G., Roper, David I., Crick, Dean C., Britton, Warwick J. and Payne, Richard J. (2017) Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nature Communications, 8 . 14414 . doi:10.1038/ncomms14414 ISSN 2041-1723.
National Science Foundation (U.S.) (NSF)
Bugg, Tim, Rodolis, Maria T., Mihalyi, Agnes and Jamshidi, Shirin (2016) Inhibition of phospho-MurNAc-pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage <phi>X174 lysis protein E, and cationic antibacterial peptides. Bioorganic and Medicinal Chemistry . doi:10.1016/j.bmc.2016.03.018 ISSN 0968-0896.
Rodolis, Maria T., Mihalyi, Agnes, Ducho, Christian, Eitel, Kornelia, Gust, Bertolt, Goss, Rebecca J. M. and Bugg, Tim (2014) Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein–protein interaction site in translocase MraY. Chemical Communications, 50 (86). pp. 13023-13025. doi:10.1039/c4cc06516f ISSN 1359-7345.
Natural Environment Research Council (Great Britain) (NERC)
Rashid, Goran M. M., Duran-Pena, Maria Jesus, Rahmanpour, Rahman , Sapsford, Devin and Bugg, Tim (2017) Delignification and enhanced gas release from soil containing Lignocellulose by treatment with bacterial lignin degraders. Journal of Applied Microbiology, 123 (1). pp. 159-171. doi:10.1111/jam.13470 ISSN 1364-5072.
Zhu, Yijun , Jameson, Eleanor, Cosatti, Marialuisa , Schäfer, Hendrik, Rajakumar, Kumar , Bugg, Tim and Chen, Yin (2014) Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota. Proceedings of the National Academy of Sciences of the United States of America, 111 (11). pp. 4268-4273. doi:10.1073/pnas.1316569111 ISSN 0027-8424.
Natural Sciences and Engineering Research Council Canada (NSERC)
Roberts, Joseph N., Singh, Rahul, Grigg, Jason C., Murphy, Michael E. P., Bugg, Tim and Eltis, Lindsay D. (2011) Characterization of dye-decolorizing peroxidases from Rhodococcus jostii RHA1. Biochemistry, Vol.50 (No.23). pp. 5108-5119. doi:10.1021/bi200427h ISSN 0006-2960.
Natural Sciences and Engineering Research Council of Canada
Paradis-Bleau, Catherine, Lloyd, Adrian, Sanschagrin, Francois, Maaroufi, Halim, Clarke, Thomas B., Blewett, Ann, Dowson, Christopher G., Roper, David I., Bugg, Tim and Levesque, Roger C. (2009) Pseudomonas aeruginosa MurE amide ligase : enzyme kinetics and peptide inhibitor. Biochemical Journal, Vol.421 (No. 2). pp. 263-272. doi:10.1042/BJ20081395 ISSN 0264-6021.
Nederlandse Organisatie voor Wetenschappelijk Onderzoek [Netherlands Organisation for Scientific Research] (NWO)
López-Ráez, Juan A., Kohlen, Wouter, Charnikhova, Tatsiana, Mulder, Patrick, Undas, Anna K., Sergeant, Martin J., Verstappen, Francel, Bugg, Tim, Thompson, Andrew J., Ruyter-Spira, Carolien and Bouwmeester, Harro (2010) Does abscisic acid affect strigolactone biosynthesis? New Phytologist, Vol.87 (No.2). pp. 343-354. doi:10.1111/j.1469-8137.2010.03291.x ISSN 0028-646X.
Networks of Centres of Excellence (Canada)
Paradis-Bleau , Catherine, Lloyd, Adrian, Sanschagrin, François, Clark, Tom, Blewett, Ann, Bugg, Tim and Levesque, Roger C. (2008) Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. BMC Biochemistry, Vol.9 (No.33). doi:10.1186/1471-2091-9-33 ISSN 1471-2091.
New South Wales Government
Tran, Anh T., Watson, Emma E., Pujari, Venugopal, Conroy, Trent, Dowman, Luke J., Giltrap, Andrew M., Pang, Angel, Wong, Weng-Ruh, Linington, Roger G., Saunders, Jessica, Charman, Susan A., West, Nicholas P., Bugg, Tim, Tod, Julie, Dowson, Christopher G., Roper, David I., Crick, Dean C., Britton, Warwick J. and Payne, Richard J. (2017) Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis. Nature Communications, 8 . 14414 . doi:10.1038/ncomms14414 ISSN 2041-1723.
Quebecois de la Recherche sur la Nature et les Technologies
Paradis-Bleau, Catherine, Lloyd, Adrian, Sanschagrin, Francois, Maaroufi, Halim, Clarke, Thomas B., Blewett, Ann, Dowson, Christopher G., Roper, David I., Bugg, Tim and Levesque, Roger C. (2009) Pseudomonas aeruginosa MurE amide ligase : enzyme kinetics and peptide inhibitor. Biochemical Journal, Vol.421 (No. 2). pp. 263-272. doi:10.1042/BJ20081395 ISSN 0264-6021.
Royal Society (Great Britain)
Zhu, Yijun , Jameson, Eleanor, Cosatti, Marialuisa , Schäfer, Hendrik, Rajakumar, Kumar , Bugg, Tim and Chen, Yin (2014) Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota. Proceedings of the National Academy of Sciences of the United States of America, 111 (11). pp. 4268-4273. doi:10.1073/pnas.1316569111 ISSN 0027-8424.
Trunkfield, Amy E., Gurcha, Sudagar S., Besra, Gurdyal S. and Bugg, Tim (2010) Inhibition of escherichia coli glycosyltransferase MurG and mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics. Bioorganic & Medicinal Chemistry, Vol.18 (No.7). pp. 2651-2663. doi:10.1016/j.bmc.2010.02.026 ISSN 0968-0896.
Shanghai Municipal Scientific Committee
Xu, Xiu-Hua, Trunkfield, Amy E., Bugg, Tim and Qing, Feng-Ling (2008) Synthesis of gem-difluorinated nucleoside analogues of the liposidomycins and evaluation as MraY inhibitors. Organic & Biomolecular Chemistry, Vol.6 (No.1). pp. 157-161. doi:10.1039/b713068f ISSN 1477-0520.
Sixth Framework Programme (European Commission) (FP6)
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
Mainardi, Jean-Luc, Villet, Regis, Bugg, Tim, Mayer, Claudine and Arthur, Michel (2008) Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria. FEMS Microbiology Reviews, Vol.32 (No.2). pp. 386-408. ISSN 0168-6445 doi:10.1111/j.1574-6976.2007.00097.x
Bouhss, Ahmed, Trunkfield, Amy E., Bugg, Tim and Mengin-Lecreulx, Dominique (2008) The biosynthesis of peptidoglycan lipid-linked intermediates. FEMS Microbiology Reviews, Vol.32 (No.2). pp. 208-233. ISSN 0168-6445 doi:10.1111/j.1574-6976.2007.00089.x
Syngenta Seeds Ltd.
Awan, Sajjad Zahoor, Chandler, Jake Owen, Harrison, Peter J., Sergeant, Martin J., Bugg, Tim and Thompson, Andrew David (2017) Promotion of germination using hydroxamic acid inhibitors of 9-cis-epoxycarotenoid dioxygenase. Frontiers in Plant Science, 8 . 357. doi:10.3389/fpls.2017.00357 ISSN 1664-462X.
Harrison, Peter J., Newgas, Sophie A., Descombes, Flora, Shepherd, Sarah A., Thompson, Andrew J. and Bugg, Tim (2015) Biochemical characterization and selective inhibition of β-carotenecis-transisomerase D27 and carotenoid cleavage dioxygenase CCD8 on the strigolactone biosynthetic pathway. FEBS Journal . doi:10.1111/febs.13400 ISSN 1742-464X.
Technology Strategy Board (Great Britain)
Mycroft, Zoe, Gomis, Maria, Mine, Paul, Law, Paul and Bugg, Tim (2015) Biocatalytic conversion of lignin to aromatic dicarboxylic acids in Rhodococcus jostii RHA1 by re-routing aromatic degradation pathways. Green chemistry, 17 (11). pp. 4974-4979. doi:10.1039/c5gc01347j ISSN 1463-9262.
Tuck Foundation
Rashid, Goran M. M., Taylor, Charles R. (Charles Robert), Liu, Yangqingxu, Zhang, Xiaoyang, Rea, Dean, Fülöp, Vilmos and Bugg, Tim (2015) Identification of manganese superoxide dismutase from Sphingobacterium sp. T2 as a novel bacterial enzyme for lignin oxidation. ACS chemical biology, 10 (10). pp. 2286-2294. doi:10.1021/acschembio.5b00298 ISSN 1554-8929.
University of Warwick
Bugg, Tim, Rodolis, Maria T., Mihalyi, Agnes and Jamshidi, Shirin (2016) Inhibition of phospho-MurNAc-pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage <phi>X174 lysis protein E, and cationic antibacterial peptides. Bioorganic and Medicinal Chemistry . doi:10.1016/j.bmc.2016.03.018 ISSN 0968-0896.
Rahmanpour, Rahman and Bugg, Tim (2013) Assembly in vitro of rhodococcus jostii RHA1 encapsulin and peroxidase DypB to form a nano-compartment. FEBS Journal, Volume 280 (Issue 9). pp. 2097-2104. doi:10.1111/febs.12234 ISSN 1742-464x.
Bugg, Tim, Ahmad, Mark, Hardiman, Elizabeth M. and Singh, Rahul (2011) The emerging role for bacteria in lignin degradation and bio-product formation. Current Opinion in Biotechnology, Vol.22 (No.3). pp. 394-400. doi:10.1016/j.copbio.2010.10.009 ISSN 0958-1669.
Trunkfield, Amy E., Gurcha, Sudagar S., Besra, Gurdyal S. and Bugg, Tim (2010) Inhibition of escherichia coli glycosyltransferase MurG and mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics. Bioorganic & Medicinal Chemistry, Vol.18 (No.7). pp. 2651-2663. doi:10.1016/j.bmc.2010.02.026 ISSN 0968-0896.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
University of Warwick. Innovative Materials Research Centre
Ahmad, Mark, Taylor, C. R. (Charles R.), Pink, David, Burton, Kerry S., Eastwood, Daniel C., Bending, G. D. and Bugg, Tim (2010) Development of novel assays for lignin degradation : comparative analysis of bacterial and fungal lignin degraders. Molecular BioSystems, Vol.6 (No.5). pp. 815-821. doi:10.1039/b908966g ISSN 1742-206X.
Warwick Innovative Manufacturing Research Centre (IMRC)
Bugg, Tim, Ahmad, Mark, Hardiman, Elizabeth M. and Rahmanpour, Rahman (2011) Pathways for degradation of lignin in bacteria and fungi. Natural Product Reports, Vol.28 (No.12). pp. 1883-1896. doi:10.1039/c1np00042j ISSN 0265-0568.
Wellcome Trust (London, England)
Trunkfield, Amy E., Gurcha, Sudagar S., Besra, Gurdyal S. and Bugg, Tim (2010) Inhibition of escherichia coli glycosyltransferase MurG and mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics. Bioorganic & Medicinal Chemistry, Vol.18 (No.7). pp. 2651-2663. doi:10.1016/j.bmc.2010.02.026 ISSN 0968-0896.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
This list was generated on Thu Apr 25 08:09:24 2024 BST.