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Number of items: 44.

Sandhu, Sandeep, Schouten, James A., Thompson, Julie, Davis, Mark and Bugg, Timothy D. H.. (2012) Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor. The Analyst, Vol.137 (No.5). pp. 1130-1136. ISSN 0003-2654

Bugg, Timothy D. H.. (2012) Biosynthesis : imaging cell-wall biosynthesis live. Nature Chemistry, Vol.5 (No.1). pp. 10-12. ISSN 1755-4330

Bugg, Tim, Ahmad, Mark, Hardiman, Elizabeth M. and Rahmanpour, Rahman. (2011) Pathways for degradation of lignin in bacteria and fungi. Natural Product Reports, Vol.28 (No.12). pp. 1883-1896. ISSN 0265-0568

Bugg, Tim, Braddick, Darren, Dowson, Christopher G. and Roper, David I.. (2011) Bacterial cell wall assembly : still an attractive antibacterial target. Trends in Biotechnology, Vol.29 (No.4). pp. 167-173. ISSN 0167-7799

Roberts, Joseph N., Singh, Rahul, Grigg, Jason C., Murphy, Michael E. P., Bugg, Tim and Eltis, Lindsay D.. (2011) Characterization of dye-decolorizing peroxidases from Rhodococcus jostii RHA1. Biochemistry, Vol.50 (No.23). pp. 5108-5119. ISSN 0006-2960

Ahmad, Mark, Roberts, Joseph N., Hardiman, Elizabeth M, Singh, Rahul, Eltis, Lindsay D. and Bugg, Tim. (2011) Identification of DypB from Rhodococcus jostii RHA1 as a lignin peroxidase. Biochemistry, Vol.50 (No.23). pp. 5096-5107. ISSN 0006-2960

Hattersley, J. G. (John G.), Pérez-Velázquez, J., Chappell, M. J. (Michael J.), Bearup, Daniel James, Roper, David I., Dowson, Christopher G., Bugg, Tim and Evans, N. D.. (2011) Indistinguishability and identifiability of kinetic models for the MurC reaction in peptidoglycan biosynthesis. Computer Methods and Programs in Biomedicine, Vol.104 (No.2). pp. 70-80. ISSN 01692607

Bugg, Tim, Ahmad, Mark, Hardiman, Elizabeth M. and Rahmanpour, Rahman. (2011) Pathways for degradation of lignin in bacteria and fungi. Natural Product Reports, Vol.28 (No.12). pp. 1883-1896. ISSN 0265-0568

Bugg, Tim, Ahmad, Mark, Hardiman, Elizabeth M. and Singh, Rahul. (2011) The emerging role for bacteria in lignin degradation and bio-product formation. Current Opinion in Biotechnology, Vol.22 (No.3). pp. 394-400. ISSN 0958-1669

López-Ráez, Juan A., Kohlen, Wouter, Charnikhova, Tatsiana, Mulder, Patrick, Undas, Anna K., Sergeant, Martin J., Verstappen, Francel, Bugg, Tim, Thompson, Andrew J., Ruyter-Spira, Carolien and Bouwmeester, Harro. (2010) Does abscisic acid affect strigolactone biosynthesis? New Phytologist, Vol.87 (No.2). pp. 343-354. ISSN 0028-646X

Ahmad, Mark, Taylor, C. R. (Charles R.), Pink, David, Burton, Kerry S., Eastwood, Daniel C., Bending, G. D. (Gary D.) and Bugg, Tim. (2010) Development of novel assays for lignin degradation : comparative analysis of bacterial and fungal lignin degraders. Molecular BioSystems, Vol.6 (No.5). pp. 815-821. ISSN 1742-206X

Trunkfield, Amy E., Gurcha, Sudagar S., Besra, Gurdyal S. and Bugg, Tim. (2010) Inhibition of escherichia coli glycosyltransferase MurG and mycobacterium tuberculosis Gal transferase by uridine-linked transition state mimics. Bioorganic & Medicinal Chemistry, Vol.18 (No.7). pp. 2651-2663. ISSN 0968-0896

Xin, Meite and Bugg, Tim. (2010) Biomimetic formation of 2-tropolones by dioxygenase-catalysed ring expansion of substituted 2,4-cyclohexadienones. ChemBioChem, Vol.11 (No.2). pp. 272-276. ISSN 1439-4227

Winn, M. (Michael), Goss, Rebecca J. M., Kimura, Ken-ichi and Bugg, Tim (2010) Antimicrobial nucleoside antibiotics targeting cell wall assembly : recent advances in structure-function studies and nucleoside biosynthesis. Natural Product Reports, Vol.27 (No.2). pp. 279-304. ISSN 0265-0568

Ahmad, Mark, Bugg, Timothy D. H., Clark, Andrew J., Coles, Stuart R., Collis, Alana, Kirwan, Kerry, Koncsag, Claudia I., Barker, Guy C., Burton, Kerry S., Eastwood, Daniel C. and Pink, David (2010) Wealth out of waste. In: 3rd International IUPAC Conference on Green Chemistry, Ottawa, Ontario, Canada, Aug 15-18, 2010

Bugg, Tim (2009) Oxygenases get to grips with polypeptides. Structure, Vol.17 (No.7). pp. 913-914. ISSN 0969-2126

Paradis-Bleau, Catherine, Lloyd, Adrian, Sanschagrin, Francois, Maaroufi, Halim, Clarke, Thomas B., Blewett, Ann, Dowson, Christopher G., Roper, David I., Bugg, Tim and Levesque, Roger C.. (2009) Pseudomonas aeruginosa MurE amide ligase : enzyme kinetics and peptide inhibitor. Biochemical Journal, Vol.421 (No. 2). pp. 263-272. ISSN 0264-6021

Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim. (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. ISSN 0968-0896

Sergeant, Martin J., Li, J.J., Fox, C., Brookbank, N., Rea, D, Bugg, Tim and Thompson, Andrew J.. (2009) Selective inhibition of carotenoid cleavage dioxygenases : phenotypic effects on shoot branching. Journal of Biological Chemistry, Vol.284 (No.8). pp. 5257-5264. ISSN 0021-9258

Vinatier, Virginie, Blakey, Carl B., Braddick, Darren, Johnson, Benjamin R. G., Evans, Stephen D. and Bugg, Tim. (2009) In vitro biosynthesis of bacterial peptidoglycan using D-Cys-containing precursors : fluorescent detection of transglycosylation and transpeptidation. Chemical Communications (No.27). pp. 4037-4039. ISSN 1359-7345

Brivio, Michela, Schlosrich, Janne, Ahmad, Mark, Tolond, Caroline and Bugg, Tim. (2009) Investigation of acid-base catalysis in the extradiol and intradiol catechol dioxygenase reactions using a broad specificity mutant enzyme and model chemistry. Organic & Biomolecular Chemistry, Vol.7 (No.7). pp. 1368-1373. ISSN 1477-0520

Paradis-Bleau , Catherine, Lloyd, Adrian, Sanschagrin, François, Clark, Tom, Blewett, Ann, Bugg, Tim and Levesque, Roger C. . (2008) Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. BMC Biochemistry, Vol.9 (No.33). ISSN 1471-2091

De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim. (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. ISSN 0021-9258

Rea, Dean, Hovington, Rebecca, Rakus, John F., Gerlt, John A., Fulop, Vilmos, Bugg, Tim and Roper, David I.. (2008) Crystal structure and functional assignment of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12. Biochemistry, Vol.47 (No.38). pp. 9955-9965. ISSN 0006-2960

Dodd, Charlotte E., Johnson, Benjamin R. G., Vinatier, Virginie, Bugg, Tim, Bushby, Richard J., Jeuken, Lars J. C. and Evans, Stephen D. (2008) COLL 53-Peptidoglycan biosynthesis on lipid bilayers. In: 236th National Meeting of the American-Chemical-Society, Philadelphia, PA, Aug 17-21, 2008. Published in: Abstracts of papers of the American Chemical Society, Vol.236

Xin, Meite and Bugg, Tim. (2008) Evidence from mechanistic probes for distinct hydroperoxide rearrangement mechanisms in the intradiol and extradiol catechol dioxygenases. Journal of the American Chemical Society, Vol.130 (No.31). pp. 10422-10430. ISSN 0002-7863

Dodd, Charlotte E., Johnson, Benjamin R. G., Jeuken, Lars J. C., Bugg, Tim, Bushby, Richard J. and Evans, Stephen D.. (2008) Native E. coli inner membrane incorporation in solid-supported lipid bilayer membranes. Biointerphases, Vol.3 (No.2). FA59-FA67. ISSN 1559-4106

Bugg, Tim and Ramaswamy, S. (2008) Non-heme iron-dependent dioxygenases : unravelling catalytic mechanisms for complex enzymatic oxidations. Current Opinion in Chemical Biology, Vol.12 (No.2). pp. 134-140. ISSN 1367-5931

Lloyd, Adrian J., Gilbey, Andrea M., Blewett, Anne M., De Pascale, Gianfranco, El Zoeiby, Ahmed, Levesque, Roger C., Catherwood, Anita C., Tomasz, Alexander, Bugg, Tim, Roper, David I. and Dowson, Christopher G.. (2008) Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan. Journal of Biological Chemistry, Vol.283 (No.10). pp. 6402-6417. ISSN 0021-9258

Mainardi, Jean-Luc, Villet, Regis, Bugg, Tim, Mayer, Claudine and Arthur, Michel (2008) Evolution of peptidoglycan biosynthesis under the selective pressure of antibiotics in Gram-positive bacteria. FEMS Microbiology Reviews, Vol.32 (No.2). pp. 386-408. ISSN 0168-6445

Bouhss, Ahmed, Trunkfield, Amy E., Bugg, Tim and Mengin-Lecreulx, Dominique (2008) The biosynthesis of peptidoglycan lipid-linked intermediates. FEMS Microbiology Reviews, Vol.32 (No.2). pp. 208-233. ISSN 0168-6445

Li, C. (Chen), Hassler, Melanie and Bugg, Tim. (2008) Catalytic promiscuity in the alpha/beta-hydrolase superfamily: Hydroxamic acid formation, C-C bondformation, ester and thioester hydrolysis in the C-C hydrolase family. Chembiochem, Vol.9 (No.1). pp. 71-76. ISSN 1439-4227

Lam, Wai-Ho, Rychli, Kathrin and Bugg, Tim. (2008) Cation of a novel beta-replacement reaction in the biosynthesis of 2,3-diaminobutyric acid in peptidylnucleoside mureidomycin A. Organic & Biomolecular Chemistry, Vol.6 (No.11). pp. 1912-1917. ISSN 1477-0520

Lam, Wai-Ho, Rychli, Kathrin and Bugg, Tim. (2008) Identification of a novel β-replacement reaction in the biosynthesis of 2,3-diaminobutyric acid in peptidylnucleoside mureidomycin A. Organic & Biomolecular Chemistry, Vol.6 (No.11). pp. 1912-1917. ISSN 1477-0520

Xu, Xiu-Hua, Trunkfield, Amy E., Bugg, Tim and Qing, Feng-Ling. (2008) Synthesis of gem-difluorinated nucleoside analogues of the liposidomycins and evaluation as MraY inhibitors. Organic & Biomolecular Chemistry, Vol.6 (No.1). pp. 157-161. ISSN 1477-0520

Rea, Dean, Fueloep, Vilmos, Bugg, Tim and Roper, David I.. (2007) Structure and mechanism of HpcH : a metal ion dependent class II aldolase from the homoprotocatechuate degradation pathway of Escherichia coli. Journal of Molecular Biology, Vol.373 (No.4). pp. 866-876. ISSN 0022-2836

Xin, Meite and Bugg, Tim (2007) BIOL 223-Mechanistic studies of the intradiol catechol dioxygenases. In: UNSPECIFIED. Published in: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 234

Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Roper, David I., Dowson, Christopher G. and Bugg, Tim. (2007) Adenosine phosphonate inhibitors of lipid II: Alanyl tRNA ligase MurM from Streptococcus pneumoniae. Bioorganic & Medicinal Chemistry Letters, Vol.17 (No.16). pp. 4654-4656. ISSN 0960-894X

Li, Jian-Jun and Bugg, Tim. (2007) Investigation of a general base mechanism for ester hydrolysis in C-C hydrolase enzymes of the alpha/beta-hydrolase superfamily: a novel mechanism for the serine catalytic triad. ORGANIC & BIOMOLECULAR CHEMISTRY, 5 (3). pp. 507-513. ISSN 1477-0520

Schlosrich, Janne, Eley, Kirstin L., Crowley, Patrick J. and Bugg, Tim. (2006) Directed evolution of a non-heme-iron-dependent extradiol catechol dioxygenase: Identification of mutants with intradiol oxidative cleavage activity. CHEMBIOCHEM, 7 (12). pp. 1899-1908. ISSN 1439-4227

Li, Chen, Li, Jian-Jun, Montgomery, Mark G., Wood, Stephen P. and Bugg, Tim. (2006) Catalytic role for Arginine 188 in the C-C hydrolase catalytic mechanism for Escherichia coli MhpC and Burkholderia xenovorans LB400 BphD. BIOCHEMISTRY, 45 (41). pp. 12470-12479. ISSN 0006-2960

Li, Jian-Jun, Li, Chen, Blindauer, Claudia A. and Bugg, Tim. (2006) Evidence for a gem-diol reaction intermediate in bacterial C-C hydrolase enzymes BphD and MhpC from C-13 NMR spectroscopy. BIOCHEMISTRY, 45 (41). pp. 12461-12469. ISSN 0006-2960

Schouten, James A., Bagga, Sangeev, Lloyd, Adrian J., de Pascale, Gianfranco, Dowson, Christopher G., Roper, David I. and Bugg, Tim. (2006) Fluorescent reagents for in vitro studies of lipid-linked steps of bacterial peptidoglycan biosynthesis: derivatives of UDPMurNAc-pentapeptide containing D-cysteine at position 4 or 5. MOLECULAR BIOSYSTEMS, 2 (10). pp. 484-491. ISSN 1742-206X

Mendel, Sharon, Holbourn, Joanne M., Schouten, James A. and Bugg, Tim. (2006) Interaction of the transmembrane domain of lysis protein E from bacteriophage phi X174 with bacterial translocase MraY and peptidyi-prolyl isomerase SlyD. MICROBIOLOGY-SGM, 152 (Part 10). pp. 2959-2967. ISSN 1350-0872

This list was generated on Sat May 18 14:24:29 2013 BST.
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