2020

Dean, Conor, Rajkumar, Sundaram, Roesner, Stefan, Carson, Nessa, Clarkson, Guy J., Wills, Martin, Jones, Matthew L. and Shipman, Michael (2020) Readily accessible sp3-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality. Chemical Science . doi:10.1039/C9SC04849A (In Press)

2019

Riemer, Nastja, Shipman, Michael, Wessig, Pablo and Schmidt, Bernd (2019) Iterative arylation of itaconimides with diazonium salts through electrophilic Palladium catalysis : divergent β-H-elimination pathways in repetitive Matsuda-Heck reactions. The Journal of Organic Chemistry . doi:10.1021/acs.joc.9b00627 (In Press)

Roesner, Stefan, Saunders, George J., Wilkening, Ina, Jayawant, Eleanor, Geden, Joanna V., Kerby, Paul D., Dixon, Ann M., Notman, Rebecca and Shipman, Michael (2019) Macrocyclisation of small peptides enabled by oxetane incorporation. Chemical Science . doi:10.1039/C8SC05474F (In Press)

2018

Riemer, Martin, Uzunova, Veselina, Riemer, Nastja, Clarkson, Guy J., Pereira, Nicole, Napier, R. (Richard) and Shipman, Michael (2018) Phyllostictine A : total synthesis, structural verification and determination of substructure responsible for plant growth inhibition. Chemical Communications, 54 (52). pp. 7211-7214. doi:10.1039/c8cc03349h

McDougall, Laura, Draper, Emily Rose, Beadle, Jonathan D., Shipman, Michael, Raubo, Piotr, Jamieson, Andrew George and Adams, Dave (2018) Enzymatically-stable oxetane-based dipeptide hydrogels. Chemical Communications . doi:10.1039/C7CC09701H (In Press)

Pancholi, Alpa K., Iacobini, Greg P., Clarkson, Guy J., Porter, David and Shipman, Michael (2018) Synthesis of 4,5-diazaspiro[2.3]hexanes and 1,2-diazaspiro[3.3]heptanes as hexahydropyridazine analogues. The Journal of Organic Chemistry, 83 (1). pp. 491-498. doi:10.1021/acs.joc.7b02622

2017

Beadle, Jonathan D., Knuhtsen, Astrid, Hoose, Alex, Raubo, Piotr, Jamieson, Andrew G. and Shipman, Michael (2017) Solid-phase synthesis of oxetane modified peptides. Organic Letters, 19 (12). pp. 3303-3306. doi:10.1021/acs.orglett.7b01466

Rajkumar, Sundaram, Clarkson, Guy J. and Shipman, Michael (2017) Regio- and stereocontrolled synthesis of 3-substituted 1,2-diazetidines by asymmetric allylic amination of vinyl epoxide. Organic Letters, 19 (8). pp. 2058-2061. doi:10.1021/acs.orglett.7b00653

2016

Hsueh, Nathanael, Clarkson, Guy J. and Shipman, Michael (2016) Functionalization of alkenes through telescoped continuous flow aziridination processes. Organic Letters, 18 (9). pp. 4908-4911. doi:10.1021/acs.orglett.6b02349

Pancholi, Alpa K., Geden, Joanna V., Clarkson, Guy J. and Shipman, Michael (2016) Asymmetric synthesis of 2-substituted Azetidin-3-ones via metalated SAMP/RAMP hydrazones. Journal of Organic Chemistry, 81 (17). pp. 7984-7992. doi:10.1021/acs.joc.6b01284

2015

Shipman, Michael, Beadle, Jonathan D., Powell, Nicola Helen, Raubo, Piotr and Clarkson, Guy J. (2015) Synthesis of oxetane- and azetidine-containing spirocycles related to the 2,5-diketopiperazine framework. Synlett, 27 (1). pp. 169-172. doi:10.1055/s-0035-1560593

Coe, Samuel, Pereira, Nicole, Geden, Joanna V., Clarkson, Guy J., Fox, David J., Napier, R. (Richard), Neve, Paul and Shipman, Michael (2015) Ring closing metathesis reactions of α-methylene-β-lactams : application to the synthesis of a simplified phyllostictine analogue with herbicidal activity. Organic & biomolecular chemistry, Volume 13 (Number 28). pp. 7655-7663. doi:10.1039/c5ob00890e

Hsueh, Nathanael, Clarkson, Guy J. and Shipman, Michael (2015) Generation and ring opening of aziridines in telescoped continuous flow processes. Organic Letters, 17 (14). pp. 3632-3635. doi:10.1021/acs.orglett.5b01777

2014

Powell, Nicola, Clarkson, Guy J., Notman, Rebecca, Raubo, Piotr, Martin, Nathaniel G. and Shipman, Michael (2014) Synthesis and structure of oxetane containing tripeptide motifs. Chemical Communications, 50 (63). pp. 8797-8800. doi:10.1039/C4CC03507K

Beasley, Benjamin O., Alli-Balogun, Abimbola, Clarkson, Guy J. and Shipman, Michael (2014) Pictet–Spengler reactions of oxetan-3-ones and related heterocycles. Tetrahedron Letters, Volume 55 (Number 2). pp. 541-543. doi:10.1016/j.tetlet.2013.11.077

2013

Geden, Joanna V., Beasley, Benjamin, Clarkson, Guy J. and Shipman, Michael (2013) Asymmetric synthesis of 2-substituted oxetan-3-ones via metalated SAMP/RAMP hydrazones. The Journal of Organic Chemistry, Volume78 (Number 23). pp. 12243-12250. doi:10.1021/jo4020485

Aspray, T. J., Jones, E. Eirian, Davies, M. W, Shipman, Michael and Bending, G. D. (2013) Increased hyphal branching and growth of ectomycorrhizal fungus Lactarius rufus by the helper bacterium Paenibacillus sp. Mycorrhiza, Volume 23 (Number 5). pp. 403-410. doi:10.1007/s00572-013-0483-1

Hough, Alexander J., Prokes, Ivan, Tucker, James H. R., Shipman, Michael and Walsh, Tiffany R. (2013) Photochemical control of molecular motion associated with pyramidal inversion. Chemical Communications, Volume 49 (Number 59). pp. 6683-6685. doi:10.1039/c3cc43036g

Hoang, Cam Thuy, Prokes, Ivan, Clarkson, Guy J., Rowland, M. J., Tucker, James H. R., Shipman, Michael and Walsh, Tiffany R. (2013) Study of boron–nitrogen dative bonds using azetidine inversion dynamics. Chemical Communications, Volume 49 (Number 25). pp. 2509-2511. doi:10.1039/c3cc36159d

Sullivan, Paul J., Schumann, Stefan, Da Campo, Raffaello, Howells, Thomas J., Duraud, Amelie, Shipman, Michael, Hatton, Ross A. and Jones, T. S. (Tim S.) (2013) Ultra-high voltage multijunction organic solar cells for low-power electronic applications. Advanced Energy Materials, Vol.3 (No.2). pp. 239-244. doi:10.1002/aenm.201200560

Geden, Joanna V., Pancholi, Alpa K. and Shipman, Michael (2013) Palladium-catalyzed multicomponent synthesis of 2-aryl-2-imidazolines from aryl halides and diamines. The Journal of Organic Chemistry, Volume 78 (Number 8). pp. 4158-4164. doi:10.1021/jo400252n

2012

Griffin, Karen, Montagne, Cyril, Hoang, Cam Thuy, Clarkson, Guy J. and Shipman, Michael (2012) ChemInform abstract : Lewis acid promoted intramolecular (3 + 2) “cycloadditions” of methyleneaziridines with alkene and alkyne acceptors. ChemInform, Vol.43 (No.25). doi:10.1002/chin.201225125

Beasley, B., Clarkson, Guy J. and Shipman, Michael (2012) Passerini reactions for the efficient synthesis of 3,3-disubstituted oxetanes. Tetrahedron Letters, Vol.53 (No.24). pp. 2951-2953. doi:10.1016/j.tetlet.2012.03.065

Griffin, Karen, Montagne, Cyril, Hoang, Cam Thuy, Clarkson, Guy J. and Shipman, Michael (2012) Lewis acid promoted intramolecular (3 + 2) ‘cycloadditions’ of methyleneaziridines with alkene and alkyne acceptors. Organic & Biomolecular Chemistry, Vol.10 (No.5). pp. 1032-1039. doi:10.1039/c1ob06578e

Iacobini, Greg, Porter, David and Shipman, Michael (2012) Chemo- and enantioselective Rh-catalysed hydrogenation of 3-methylene-1,2-diazetidines: application to vicinal diamine synthesis. Chemical Communications, Vol. 48 (No. 79). p. 9852. doi:10.1039/c2cc35445d

2011

Turner, Penelope A., Griffin, Ellanna M., Whatmore, Jacqueline L. and Shipman, Michael (2011) Biologically active tetrahydroxanthones by sequential Pd-catalyzed C-O and C-C bond construction. In: 242nd National Meeting of the American-Chemical-Society (ACS), Denver, CO, 28 Aug - 1 Sep 2011. Published in: American Chemical Society. Abstracts of Papers (at the National Meeting), Vol.242 88-ORGN. ISSN 0065-7727.

Iacobini, Greg, Shipman, Michael, Porter, David, Brownlee, Michael, Inglis, Graham G. and Clarkson, Guy J. (2011) Synthesis and applications of 3-methylene-1,2-diazetidines : a new class of heterocycle. In: 242nd National Meeting of the American-Chemical-Society (ACS), Denver, CO, 28 Aug - 1 Sep 2011. Published in: American Chemical Society. Abstracts of Papers (at the National Meeting), Vol.242 303-ORGN . ISSN 0065-7727.

Sullivan, Paul J., Duraud, Amelie, Hancox, Ian, Beaumont, Nicola L., Mirri, Giorgio, Tucker, James H. R., Hatton, Ross A., Shipman, Michael and Jones, T. S. (Tim S.) (2011) Halogenated boron subphthalocyanines as light harvesting electron acceptors in organic photovoltaics. Advanced Energy Materials, Vol.1 (No.3). pp. 352-355. doi:10.1002/aenm.201100036

Brown, M. J. (Michael J.), Clarkson, Guy J., Inglis, Graham G. and Shipman, Michael (2011) Synthesis and functionalization of 3-alkylidene-1,2-diazetidines using transition metal catalysis. Organic Letters, Volume 13 (Number 7). pp. 1686-1689. doi:10.1021/ol200193n

Turner, Penelope A., Griffin, Ellanna M., Whatmore, Jacqueline and Shipman, Michael (2011) Tetrahydroxanthones by sequential Pd-catalyzed C−O and C−C bond construction and use in the identification of the “antiausterity” pharmacophore of the kigamicins. Organic Letters, Volume 13 (Number 5). pp. 1056-1059. doi:10.1021/ol103103n

2010

Brown, Michael J., Clarkson, Guy J., Fox, David J., Inglis, Graham G. and Shipman, Michael (2010) Critical importance of leaving group 'softness' in nucleophilic ring closure reactions of ambident anions to 1,2-diazetidines. Tetrahedron Letters, Vol.51 (No.2). pp. 382-384. doi:10.1016/j.tetlet.2009.11.024

Giordano, Luciana, Hoang, Cam T., Shipman, Michael, Tucker, James H. R. and Walsh, Tiffany R. (2010) Aziridine scaffolds for the detection and quantification of hydrogen-bonding interactions through transition-state stabilization. Angewandte Chemie International Edition, Vol.50 (No.3). pp. 741-744. doi:10.1002/anie.201005580

2009

Finerty, Matthew J., Bingham, John P., Hartley, John A. and Shipman, Michael (2009) Azinomycin bisepoxides containing rigid aromatic linkers: synthesis, cytotoxicity and DNA interstrand cross-linking activity. Tetrahedron Letters, Vol.50 (No.26 Sp. Iss. SI). pp. 3648-3650. doi:10.1016/j.tetlet.2009.03.123

Mumford, Peter M., Tarver, Gary J. and Shipman, Michael (2009) Four-component reaction for the preparation of alpha-Amino phosphonates from methyleneaziridines. Journal of Organic Chemistry, Vol.74 (No.9). pp. 3573-3575. doi:10.1021/jo9004958

Musio, Biagia, Clarkson, Guy J., Shipman, Michael, Florio, Saverio and Luisi, Renzo (2009) Synthesis of optically active arylaziridines by regio- and stereospecific lithiation of N-Bus-phenylaziridine. Organic Letters, Vol.11 (No.2). pp. 325-328. doi:10.1021/ol802487v

2008

Cariou, Claire C. A., Clarkson, Guy J. and Shipman, Michael (2008) Rapid synthesis of 1,3,4,4-tetrasubstituted beta-lactams from methyleneaziridines using a four-component reaction. The Journal of Organic Chemistry, Vol.73 (No.24). pp. 9762-9764. doi:10.1021/jo801664g

Gallienne, Estelle, Muccioli, Giulio G., Lambert, Didier M. and Shipman, Michael (2008) Microwave-assisted four-component reaction for the synthesis of a monothiohydantoin inhibitor of a fatty acid amide hydrolase. Tetrahedron Letters, Volume 49 (Number 46). pp. 6495-6497. doi:10.1016/j.tetlet.2008.08.100

Nalli, Stefano M., Clarkson, Guy J., Franklin, Alison S., Bellone, Graziella and Shipman, Michael (2008) Iminophosphorane-mediated synthesis of cyclic guanidines : application to the synthesis of a simplified NA22598A(1) analogue. Synlett (No.15). pp. 2339-2341. doi:10.1055/s-2008-1078279

Mumford, Peter M., Shiers, Jason J., Tarver, Gary J., Hayes, Jerome F. and Shipman, Michael (2008) Synthesis of 1,1-disubstituted tetrahydro-beta-carbolines from 2-methyleneaziridines. Tetrahedron Letters, Vol.49 (No.21). pp. 3489-3491. doi:10.1016/j.tetlet.2008.03.095

Wynne, Emma L., Clarkson, Guy J. and Shipman, Michael (2008) Stereocontrolled approach to 1-azabicyclo[4.1.0]heptanes : application to the synthesis of trans-2,6-disubstituted piperidines. Tetrahedron Letters, Volume 49 (Number 2). pp. 250-252. doi:10.1016/j.tetlet.2007.11.077

2007

Szekely, Joseph, Zang, Hong, Shipman, Michael and Gates, Kent S. (2007) DNA binding by analogues of the left-half of azinomycin : a minimal DNA-intercalating structure. In: Meeting of the Division of Chemical Toxicology of the American - Chemical - Society held at the 234th ACS National Meeting, Boston, MA, 19-23 Aug 2007. Published in: Chemical Research in Toxicology, Vol.20 (No.12). p. 2000. ISSN 0893-228X.

Szekely, Joseph, Zang, Hong, Shipman, Michael and Gates, Kent S. (2007) TOXI 53-characterization of a novel glutathione adduct from arachidonic acid metabolism. In: UNSPECIFIED. Published in: Abstracts of papers of the American Chemical Society, Vol.234 ISSN 0065-7727.

Oehlrich, Daniel, Vidot, Sandrine M. E., Davies, Mark W., Clarkson, Guy J. and Shipman, Michael (2007) Total synthesis of (±)-luminacin D. Tetrahedron, Vol.63 (No.22). pp. 4703-4711. doi:10.1016/j.tet.2007.03.096

Davies, Mark W., Clarke, Adam J., Clarkson, Guy J., Shipman, Michael and Tucker, James H. R. (2007) Umbrella motion in aziridines : use of simple chemical inputs to reversibly control the rate of pyramidal inversion. Chemical Communications (Number 47). pp. 5078-5080. doi:10.1039/b712447c

2006

Montagne, Cyril, Shiers, Jason J. and Shipman, Michael (2006) Rapid generation of molecular complexity using 'sequenced' multi-component reactions: one-pot synthesis of 5,5 '-disubstituted hydantoins from methyleneaziridines. TETRAHEDRON LETTERS, 47 (52). pp. 9207-9209. doi:10.1016/j.tetlet.2006.10.135

Shipman, Michael (2006) Methyleneaziridines: Unusual vehicles for organic synthesis. SYNLETT (19). pp. 3205-3217. doi:10.1055/s-2006-951566

Davies, Mark W., Shipman, Michael, Tucker, James H. R. and Walsh, Tiffany R. (2006) Control of pyramidal inversion rates by redox switching. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 128 (44). pp. 14260-14261. doi:10.1021/ja065325f

Montagne, Cyril, Prevost, Natacha, Shiers, Jason J., Prie, Gildas, Rahman, Sabitur, Hayes, Jerome F. and Shipman, Michael (2006) Generation and electrophilic substitution reactions of 3-lithio-2-methyleneaziridines. Tetrahedron, Vol.62 (No.36). pp. 8447-8457. doi:10.1016/j.tet.2006.06.083

Montagne, Cyril and Shipman, Michael (2006) Modified Bucherer-Bergs reaction for the one-pot synthesis of 5,5 '-disubstituted hydantoins from nitriles and organometallic reagents. Synlett (No.14). pp. 2203-2206. doi:10.1055/s-2006-949644