The Library
Browse by Warwick Author
Up a level |
Number of items: 187.
Journal Article
Parsons, Nick R., Basu, Joydeep and Stallard, Nigel (2024) Group sequential designs for pragmatic clinical trials with early outcomes : methods and guidance for planning and implementation. BMC Medical Research Methodology, 24 (1). 42. doi:10.1186/s12874-024-02174-w ISSN 1471-2288.
Freeman, Karoline, Jenkinson, David J., Clements, K., Wallis, M. G., Pinder, S. E., Provenzano, E., Stobart, H., Stallard, Nigel, Kearins, O., Sharma, N., Shaaban, A., Kirwan, C. C., Hilton, B., Thompson, A. M. and Taylor-Phillips, Sian (2024) Atypia detected during breast screening and subsequent development of cancer : observational analysis of the Sloane atypia prospective cohort in England. BMJ, 384 . e077039. doi:10.1136/bmj-2023-077039 ISSN 0959-535X.
Freeman, Karoline, Mansbridge, Alice, Stobart, H., Clements, K., Wallis, M. G., Pinder, S. E., Kearins, O., Shaaban, A. M., Kirwan, C. C., Wilkinson, L. S. et al.
(2024)
Evidence-informed recommendations on managing breast screening atypia : perspectives from an expert panel consensus meeting reviewing results from the sloane atypia project.
British Journal of Radiology, 97
(1154).
pp. 324-330.
doi:10.1093/bjr/tqad053
ISSN 0007-1285.
START:REACTS team (Including:
Metcalfe, Andrew J., Arnold, Susanne, Parsons, Helen, Parsons, Nicholas R., Bhabra, Gev, Brown, Jaclyn, Bush, Howard, Diokno, Michael, Elliott, Mark T., Fox, Josephine et al.
).
(2023)
Subacromial spacer for Tears Affecting Rotator cuff Tendons : a Randomised, Efficient, Adaptive Clinical Trial in Surgery (START:REACTS).
Efficacy and Mechanism Evaluation, 10
(3).
doi:10.3310/TKJY2101
ISSN 2050-4365.
START:REACTS team (Including:
Metcalfe, Andrew J., Arnold, Susanne, Parsons, Helen, Parsons, Nicholas R., Bhabra, Gev, Brown, Jaclyn, Bush, Howard, Diokno, Michael, Elliott, Mark T., Fox, Josephine et al.
).
(2023)
Subacromial spacers for adults with symptomatic, irreparable rotator cuff tears : the START:REACTS novel group sequential adaptive RCT.
Efficacy and Mechanism Evaluation, 10
(3).
pp. 1-146.
doi:10.3310/tkjy2101
ISSN 2050-4373.
Calderazzo, Silvia, Tarima, Sergey, Reid, Carissa, Flournoy, Nancy, Friede, Tim, Geller, Nancy, Rosenberger, James L, Stallard, Nigel, Ursino, Moreno, Vandemeulebroecke, Marc, Van Lancker, Kelly and Zohar, Sarah (2023) Coping with information loss and the use of auxiliary sources of data : a report from the NISS Ingram Olkin forum series on unplanned clinical trial disruptions. Statistics in Biopharmaceutical Research . doi:10.1080/19466315.2023.2211023 ISSN 1946-6315. (In Press)
Duputel, Benjamin, Stallard, Nigel, Montestruc, François, Zohar, Sarah and Ursino, Moreno (2023) Using dichotomized survival data to construct a prior distribution for a Bayesian seamless Phase II/III clinical trial. Statistical Methods in Medical Research, 32 (5). pp. 963-977. doi:10.1177/09622802231160554 ISSN 1477-0334.
Stallard, Nigel (2023) Adaptive enrichment designs with a continuous biomarker. Biometrics, 79 (1). pp. 9-19. doi:10.1111/biom.13644 ISSN 0006-341X.
Stallard, Nigel (2023) Rejoinder to discussion on βAdaptive enrichment designs with a continuous biomarkerβ. Biometrics, 79 (1). pp. 36-38. doi:10.1111/biom.13639 ISSN 1541-0420.
Khan, Josephine N., Kimani, Peter K., Glimm, Ekkehard and Stallard, Nigel (2023) Adjusting for treatment selection in phase II/III clinical trials with time to event data. Statistics in Medicine, 42 (2). pp. 146-163. doi:10.1002/sim.9606 ISSN 0277-6715.
Parker, Richard A., Weir, Christopher J., Pham, Tra My, White, Ian R., Stallard, Nigel, Parmar, Mahesh K. B., Swingler, Robert J., Dakin, Rachel S., Pal, Suvankar and Chandran, Siddharthan (2023) Statistical analysis plan for the motor neuron disease systematic multi-arm adaptive randomised trial (MND-SMART). Trials, 24 (1). 29. doi:10.1186/s13063-022-07007-z ISSN 1745-6215.
Zhan, Stella Jinran, Kunz, Cornelia Ursula and Stallard, Nigel (2023) Should the twoβtrial paradigm still be the gold standard in drug assessment? Pharmaceutical Statistics, 22 (1). pp. 96-111. doi:10.1002/pst.2262 ISSN 1539-1604.
Parsons, Nick R., Stallard, Nigel, Parsons, Helen, Haque, Aminul, Underwood, Martin, Mason, James, Khan, Iftekhar, Costa, Matthew L., Griffin, Damian R., Griffin, James, Beard, David J., Cook, Jonathan A., Davies, Loretta, Hudson, Jemma and Metcalfe, Andrew (2022) Group sequential designs in pragmatic trials : feasibility and assessment of utility using data from a number of recent surgical RCTs. BMC Medical Research Methodology, 22 (1). 256. doi:10.1186/s12874-022-01734-2 ISSN 1471-2288.
Schmidtke, Kelly, Kudrna, Laura, Noufaily, Angela, Stallard, Nigel, Skrybant, Magdalena, Russell, Samantha and Clarke, Aileen (2022) Evaluating the relationship between moral values and vaccine hesitancy in Great Britain during the COVID-19 pandemic : a cross-sectional survey. Social Science & Medicine, 308 . 115218. doi:10.1016/j.socscimed.2022.115218 ISSN 02779536.
Wong, Charis, Dakin, Rachel S., Williamson, Jill, Newton, Judith, Steven, Michelle, Colville, Shuna, Stavrou, Maria, Gregory, Jenna M., Elliott, Elizabeth, Mehta, Arpan R., Chataway, Jeremy, Swingler, Robert J., Parker, Richard Anthony, Weir, Christopher J., Stallard, Nigel, Parmar, Mahesh K. B., Macleod, Malcolm R., Pal, Suvankar and Chandran, Siddharthan (2022) Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART) : a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease. BMJ Open, 12 (7). e064173. doi:10.1136/bmjopen-2022-064173 ISSN 2044-6055.
Dane, Aaron, Rex, John H., Newell, Paul and Stallard, Nigel (2022) The value of the information that can be generated : optimizing study design to enable the study of treatments addressing an unmet need for rare pathogens. Open Forum Infectious Diseases, 9 (7). ofac266. doi:10.1093/ofid/ofac266 ISSN 2328-8957.
START:REACTS team (Including: Metcalfe, Andrew J., Parsons, Helen, Parsons, Nicholas R., Brown, Jaclyn, Fox, Josephine, Gemperle Mannion, Elke, Haque, Aminul, Hutchinson, Charles E., Kearney, Rebecca S., Khan, Iftekhar, Lawrence, Tom, Mason, James, Stallard, Nigel, Underwood, Martin and Drew, Stephen). (2022) Subacromial balloon spacer for irreparable rotator cuff tears of the shoulder (START:REACTS) : a group-sequential, double-blind, multicentre randomised controlled trial. The Lancet, 399 (10339). pp. 1954-1963. doi:10.1016/S0140-6736(22)00652-3 ISSN 0140-6736.
Li, Vivien, Leurent, Baptiste, Barkhof, Frederik, Braisher, Marie, Cafferty, Fay H., Ciccarelli, Olga, Eshaghi, Arman, Gray, Emma, Nicholas, Jennifer M., Parmar, Mahesh K. B., Peryer, Guy, Robertson, Jenny, Stallard, Nigel, Wason, James and Chataway, Jeremy (2022) Designing multi-arm multistage adaptive trials for neuroprotection in progressive multiple slerosis. Neurology, 98 (18). pp. 754-764. doi:10.1212/WNL.0000000000200604 ISSN 0028-3878.
Gallacher, Daniel C., Stallard, Nigel, Kimani, Peter K., GΓΆkalp, Elvan and Branke, Juergen (2022) Development of a model to demonstrate the impact of NICE cost-effectiveness assessment on health utility for targeted medicines. Health Economics, 31 (2). pp. 417-430. doi:10.1002/hec.4459 ISSN 1057-9230.
RECOVERY-RS Collaborators (Including:
Perkins, Gavin D., Ji, Chen, Connolly, Bronwen A., Couper, Keith, Lall, Ranjit, Baillie, J. Kenneth, Bradley, Judy M., Dark, Paul, Dave, Chirag, De Soyza, Anthony et al.
).
(2022)
Effect of noninvasive respiratory strategies on intubation or mortality among patients with acute hypoxemic respiratory failure and COVID-19.
JAMA: The Journal of the American Medical Association, 327
.
pp. 546-558.
doi:10.1001/jama.2022.0028
ISSN 0098-7484.
Jenkinson, David J., Freeman, Karoline, Clements, Karen, Hilton, Bridget, Dulson-Cox, Joanne, Kearins, Olive, Stallard, Nigel, Wallis, Matthew G., Sharma, Nisha, Kirwan, Cliona, Pinder, Sarah, Provenzano, Elena, Shaaban, Abeer M., Stobart, Hilary, McDonnell, Samantha J., Thompson, Alastair M. and Taylor-Phillips, Sian (2022) Breast screening atypia and subsequent development of cancer : protocol for an observational analysis of the Sloane database in England (Sloane atypia cohort study). BMJ Open, 12 (1). e058050. doi:10.1136/bmjopen-2021-058050 ISSN 2044-6055.
Gallacher, Daniel C., Kimani, Peter K. and Stallard, Nigel (2022) Biased survival predictions when appraising health technologies in heterogeneous populations. PharmacoEconomics - Open . pp. 109-120. doi:10.1007/s40273-021-01082-x ISSN 2509-4262.
Wong, Charis, Stavrou, Maria, Elliott, Elizabeth, Gregory, Jenna M., Leigh, Nigel, Pinto, Ashwin A., Williams, Timothy L., Chataway, Jeremy, Swingler, Robert, Parmar, Mahesh K. B. et al.
(2021)
Clinical trials in amyotrophic lateral sclerosis : a systematic review and perspective.
Brain Communications, 3
(4).
fcab242.
doi:10.1093/braincomms/fcab242
ISSN 2632-1297.
Saravanan, Ponnusamy, Sukumar, Nithya, Adaikalakoteswari, Antonysunil, Goljan, Ilona, Venkataraman, Hema, Gopinath, Amitha, Bagias, Christos, Yajnik, Chittaranjan S., Stallard, Nigel, Ghebremichael-Weldeselassie, Yonas and Fall, Caroline (2021) Association of maternal vitamin B12 and folate levels in early pregnancy with gestational diabetes : a prospective UK cohort study (PRiDE study). Diabetologia, 64 . pp. 2170-2182. doi:10.1007/s00125-021-05510-7 ISSN 0012-186X.
Lee, Kim May, Brown, Louise C., Jaki, Thomas, Stallard, Nigel and Wason, James (2021) Statistical consideration when adding new arms to ongoing clinical trials : the potentials and the caveats. Trials, 22 (1). 203. doi:10.1186/s13063-021-05150-7 ISSN 1745-6215.
Gallacher, Daniel, Kimani, Peter and Stallard, Nigel (2021) Extrapolating parametric survival models in Health Technology Assessment using model averaging : a simulation study. Medical Decision Making, 41 (4). pp. 476-484. doi:10.1177/0272989x21992297 ISSN 0272-989X.
Hee, Siew Wan, Mistry, Dipesh, Friede, Tim, Lamb, Sarah E., Stallard, Nigel, Underwood, Martin and Patel, Shilpa (2021) Identification of subgroup effect with an individual participant data meta-analysis of randomised controlled trials of three different types of therapist-delivered care in low back pain. BMC Musculoskeletal Disorders, 22 (1). 191. doi:10.1186/s12891-021-04028-8 ISSN 1471-2474.
Ursino, M. and Stallard, Nigel (2021) Bayesian approaches for confirmatory trials in rare diseases : opportunities and challenges. International Journal of Environmental Research and Public Health, 18 (3). 1022. doi:10.3390/ijerph18031022 ISSN 1660-4601.
Gallacher, Daniel C., Stallard, Nigel and Kimani, Peter K. (2021) Extrapolating parametric survival models in health technology assessment : a simulation study. Medical Decision Making, 41 (1). pp. 37-50. doi:10.1177/0272989X20973201 ISSN 0272-989X.
OPTIMA Trial Management Group (Including: Bartlett, John M. S., Bayani, Jane, Kornaga, Elizabeth N., Danaher, Patrick, Crozier, Cheryl, Piper, Tammy, Yao, Cindy Q., Dunn, Janet A., Boutros, Paul C. and Stein, Robert C.). (2020) Computational approaches to support comparative analysis of multiparametric tests : modelling versus training. PLOS ONE, 15 (9). e0238593. doi:10.1371/journal.pone.0238593 ISSN 1932-6203.
Friede, Tim, Stallard, Nigel and Parsons, Nicholas R. (2020) Adaptive seamless clinical trials using early outcomes for treatment or subgroup selection : methods, simulation model and their implementation in R. Biometrical Journal, 62 (5). doi:10.1002/bimj.201900020 ISSN 0323-3847.
Kimani, Peter K., Todd, Susan, Renfro, Lindsay A., Glimm, Ekkehard, Khan, Josephine N., Kairalla, John A. and Stallard, Nigel (2020) Point and interval estimation in two-stage adaptive designs with time to event data and biomarker-driven subpopulation selection. Statistics in Medicine, 39 (19). pp. 2568-2586. doi:10.1002/sim.8557 ISSN 0277-6715.
Perkins, Gavin D., Couper, Keith, Connolly, Bronwen, Baillie, J. Kenneth, Bradley, Judy M., Dark, Paul, De Soyza, Anthony, Gorman, Ellen, Gray, Alasdair, Hamilton, Louisa et al.
(2020)
RECOVERY- Respiratory Support : respiratory strategies for patients with suspected or proven COVID-19 respiratory failure; continuous positive airway pressure, high-flow nasal oxygen, and standard care : a structured summary of a study protocol for a randomised controlled trial.
Trials, 21
(1).
687.
doi:10.1186/s13063-020-04617-3
ISSN 1745-6215.
Kunz, Cornelia Ursula, JΓΆrgens, Silke, Bretz, Frank, Stallard, Nigel, Van Lancker, Kelly, Xi, Dong, Zohar, Sarah, Gerlinger, Christoph and Friede, Tim (2020) Clinical trials impacted by the COVID-19 pandemic : adaptive designs to the rescue? Statistics in Biopharmaceutical Research, 12 (4). pp. 461-477. doi:10.1080/19466315.2020.1799857 ISSN 1946-6315.
Stallard, Nigel, Hampson, Lisa, Benda, Norbert, Brannath, Werner, Burnett, Thomas, Friede, Tim, Kimani, Peter K., Koenig, Franz, Krisam, Johannes, Mozgunov, Pavel, Posch, Martin, Wason, James, Wassmer, Gernot, Whitehead, John, Williamson, S. Faye, Zohar, Sarah and Jaki, Thomas (2020) Efficient adaptive designs for clinical trials of interventions for COVID-19. Statistics in Biopharmaceutical Research, 12 (4). pp. 483-497. doi:10.1080/19466315.2020.1790415 ISSN 1946-6315.
De Angelis, Floriana, Connick, Peter, Parker, Richard A., Plantone, Domenico, Doshi, Anisha, John, Nevin, Stutters, Jonathan, MacManus, David, Prados, Ferran, Marshall, Ian et al.
(2020)
Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis : the MS-SMART four-arm RCT.
Efficacy and Mechanism Evaluation, 7
(3).
pp. 1-72.
doi:10.3310/eme07030
ISSN 2050-4373.
Metcalfe, Andrew J., Gemperle Mannion, Elke, Parsons, Helen, Brown, Jaclyn, Parsons, Nicholas R., Fox, Josephine, Kearney, Rebecca S., Lawrence, Thomas, Bush, Howard, McGowan, Kerri , Khan, Iftekhar, Mason, James, Hutchinson, Charles E., Gates, Simon, Stallard, Nigel, Underwood, Martin and Drew, Steve (2020) Protocol for a randomised controlled trial of subacromial spacers for tears affecting rotator cuff tendons : a randomised, efficient, adaptive clinical trial in surgery (START:REACTS). BMJ Open, 10 . e036829. doi:10.1136/bmjopen-2020-036829 ISSN 2044-6055.
Barker, K. L., Newman, M., Stallard, Nigel, Leal, J., Lowe, C. M., Javaid, M. K., Noufaily, Angela, Hughes, T., Smith, D., Gandhi, V., Cooper, C. and Lamb, S. E. (2020) Physiotherapy rehabilitation for osteoporotic vertebral fractureβa randomised controlled trial and economic evaluation (PROVE trial). Osteoporosis International, 31 . pp. 277-289. doi:10.1007/s00198-019-05133-0 ISSN 0937-941X.
Chataway, Jeremy, De Angelis, Floriana, Connick, Peter, Parker, Richard A, Plantone, Domenico, Doshi, Anisha, John, Nevin, Stutters, Jonathan, MacManus, David, Prados Carrasco, Ferran et al.
(2020)
Efficacy of three neuroprotective drugs in secondary progressive multiple sclerosis (MS-SMART) : a phase 2b, multiarm, double-blind, randomised placebo-controlled trial.
The Lancet Neurology, 19
(3).
pp. 214-225.
doi:10.1016/S1474-4422(19)30485-5
ISSN 1474-4422.
Ryan, Elizabeth G., Stallard, Nigel, Lall, Ranjit, Ji, Chen, Perkins, Gavin D. and Gates, Simon (2020) Bayesian group sequential designs for phase III emergency medicine trials : a case study using the PARAMEDIC2 trial. Trials, 21 (1). 84. doi:10.1186/s13063-019-4024-x ISSN 1745-6215.
Stallard, Nigel, Todd, Susan, Ryan, Elizabeth G. and Gates, Simon (2020) Comparison of Bayesian and frequentist group-sequential clinical trial designs. BMC Medical Research Methodology, 20 (1). 4 . doi:10.1186/s12874-019-0892-8 ISSN 1471-2288.
Parsons, Nicholas R., Stallard, Nigel, Parsons, Helen, Wells, Philip, Underwood, Martin, Mason, James and Metcalfe, Andrew J. (2019) An adaptive two-arm clinical trial using early endpoints to inform decision making : design for a study of sub-acromial spacers for repair of rotator cuff tendon tears. Trials, 20 . 694. doi:10.1186/s13063-019-3708-6 ISSN 1745-6215.
Cook, Jonathan A., Julious, Steven A., Sones, William, Hampson, Lisa V., Hewitt, Catherine, Berlin, Jesse A., Ashby, Deborah, Emsley, Richard, Fergusson, Dean A., Walters, Stephen J. et al.
(2019)
Practical help for specifying the target difference in sample size calculations for RCTs : the DELTA2 five-stage study, including a workshop.
Health Technology Assessment, 23
(60).
pp. 1-88.
doi:10.3310/hta23600
ISSN 1366-5278.
Barker, Karen L., Newman, Meredith, Stallard, Nigel, Leal, Jose, Minns Lowe, Catherine, Javaid, Muhammad K., Noufaily, Angela, Adhikari, Anish, Hughes, Tamsin, Smith, David J., Gandhi, Varsha, Cooper, Cyrus and Lamb, Sallie E. (2019) Exercise or manual physiotherapy compared with a single session of physiotherapy for osteoporotic vertebral fracture : three-arm PROVE RCT. Health Technology Assessment, 23 (44). pp. 1-318. doi:10.3310/hta23440 ISSN 1366-5278.
Ondra, Thomas, JobjΓΆrnsson, Sebastian, Beckman, Robert A., Burman, Carl-Fredrik, KΓΆnig, Franz, Stallard, Nigel and Posch, Martin (2019) Optimized adaptive enrichment designs. Statistical Methods in Medical Research, 28 (7). pp. 2096-2111. 096228021774731. doi:10.1177/0962280217747312 ISSN 1477-0334.
Lee, Kim May, Wason, James and Stallard, Nigel (2019) To add or not to add a new treatment arm to a multiarm study : a decisionβtheoretic framework. Statistics in Medicine . doi:10.1002/sim.8194 ISSN 0277-6715.
Ryan, Elizabeth G., Bruce, Julie, Metcalfe, Andrew J., Stallard, Nigel, Lamb, Sarah E., Viele, Kert, Young, Duncan and Gates, Simon (2019) Using Bayesian adaptive designs to improve phase III trials : a respiratory care example. BMC Medical Research Methodology, 19 . 99. doi:10.1186/s12874-019-0739-3 ISSN 1471-2288.
Ursino, Moreno, Yuan, Ying, Alberti, Corinne, Comets, Emmanuelle, Favrais, Geraldine, Friede, Tim, Lentz, Frederike, Stallard, Nigel and Zohar, Sarah (2019) A dose finding design for seizure reduction in neonates. Journal of the Royal Statistical Society: Series C (Applied Statistics), 68 (2). pp. 427-444. doi:10.1111/rssc.12289 ISSN 0035-9254.
Stallard, Nigel, Todd, S, Parashar, D, Kimani, P K and Renfro, L A (2019) On the need to adjust for multiplicity in confirmatory clinical trials with master protocols. Annals of Oncology, 30 (4). pp. 506-509. doi:10.1093/annonc/mdz038 ISSN 0923-7534.
Choko, Augustine T., Corbett, Elizabeth L., Stallard, Nigel, Maheswaran, Hendramoorthy, Lepine, Aurelia, Johnson, Cheryl C., Sakala, Doreen, Kalua, Thokozani, Kumwenda, Moses, Hayes, Richard and Fielding, Katherine (2019) HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in Malawi : an adaptive multi-arm, multi-stage cluster randomised trial. PLoS Medicine, 16 (1). e1002719. doi:10.1371/journal.pmed.1002719 ISSN 1549-1277.
Youssef, Haney, Collantes, Enrique, Hunter, James, Stinson, Julie, Smith, Steve, Stallard, Nigel, Been, Martin and Wong, Ling (2019) Preoperative and postoperative N-terminal pro B-type natriuretic peptide levels predict cardiac morbidity and mortality in patients undergoing colorectal cancer resection. Journal Of Colon And Rectal Cancer, 1 (3). pp. 1-9. doi:10.14302/issn.2471-7061.jcrc-18-2446 ISSN 2471-7061.
Kunz, Cornelia Ursula, Jaki, Thomas and Stallard, Nigel (2018) An alternative method to analyse the biomarker-strategy design. Statistics in Medicine, 37 (30). pp. 4636-4651. doi:10.1002/sim.7940 ISSN 0277-6715.
Day, Simon, Jonker, Anneliene Hechtelt, Lau, Lilian Pek Lian, Hilgers, Ralf-Dieter, Irony, Ilan, Larsson, Kristina, Roes, Kit C. B. and Stallard, Nigel (2018) Recommendations for the design of small population clinical trials. Orphanet Journal of Rare Diseases, 13 (1). 195. doi:10.1186/s13023-018-0931-2 ISSN 1750-1172.
Cook, Jonathan A., Julious, Steven A., Sones, William, Hampson, Lisa V., Hewitt, Catherine, Berlin, Jesse A., Ashby, Deborah, Emsley, Richard, Fergusson, Dean A., Walters, Stephen J. et al.
(2018)
DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.
British Medical Journal, 363
.
k3750.
doi:10.1136/bmj.k3750
ISSN 0959-8146.
Cook, Jonathan A., Julious, Steven A., Sones, William, Hampson, Lisa V., Hewitt, Catherine, Berlin, Jesse A., Ashby, Deborah, Emsley, Richard, Fergusson, Dean A., Walters, Stephen J. et al.
(2018)
DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.
Trials, 19
(1).
606.
doi:10.1186/s13063-018-2884-0
ISSN 1745-6215.
Cook, Jonathan A, Julious, Steven A, Sones, William, Hampson, Lisa V, Hewitt, Catherine, Berlin, Jesse A, Ashby, Deborah, Emsley, Richard, Fergusson, Dean A, Walters, Stephen J et al.
(2018)
DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.
BMJ Open, 363
.
k3750.
doi:10.1136/bmj.k3750
ISSN 2044-6055.
Friede, Tim, Posch, Martin, Zohar, Sarah, Alberti, Corinne, Benda, Norbert, Comets, Emmanuelle, Day, Simon, Dmitrienko, Alex, Graf, Alexandra, GΓΌnhan, Burak KΓΌrsad et al.
(2018)
Recent advances in methodology for clinical trials in small populations : the InSPiRe project.
Orphanet Journal of Rare Diseases, 13
(1).
186.
doi:10.1186/s13023-018-0919-y
ISSN 1750-1172.
Kimani, Peter K., Todd, Susan, Renfro, Lindsay A. and Stallard, Nigel (2018) Point estimation following two-stage adaptive threshold enrichment clinical trials. Statistics in Medicine, 37 (22). pp. 3179-3196. doi:10.1002/sim.7831 ISSN 1097-0258.
PARAMEDIC2 Collaborators (Including:
Perkins, Gavin D., Ji, Chen, Deakin, Charles D., Quinn, Tom, Nolan, Jerry P., Scomparin, Charlotte, Regan, Scott, Long, John, Slowther, Anne, Pocock, Helen et al.
).
(2018)
A randomized trial of epinephrine in out-of-hospital cardiac arrest.
New England Journal Of Medicine , 379
.
pp. 711-721.
doi:10.1056/NEJMoa1806842
ISSN 0028-4793.
MS-SMART Trialists (Including: Marshall, Ian, Thrippleton, Michael J., Bastin, Mark E., Mollison, Daisy, Dickie, David A., Chappell, Francesca M., Semple , Scott I. K., Cooper, Annette, Pavitt, Sue, Giovannoni, Gavin, Wheeler-Kingshott, Claudia A. M. Gandini , Solanky, Bhavana S., Weir, Christopher J., Stallard, Nigel, Hawkins, Clive, Sharrack, Basil, Chataway, Jeremy, Connick, Peter and Chandran, Siddharthan). (2018) Characterisation of tissue-type metabolic content in secondary progressive multiple sclerosis : a magnetic resonance spectroscopic imaging study. Journal of Neurology, 265 (8). pp. 1795-1802. doi:10.1007/s00415-018-8903-y ISSN 0340-5354.
Jepson, Marcus, Elliott, Daisy, Conefrey, Carmel, Wade, Julia, Rooshenas, Leila, Wilson, Caroline, Beard, David, Blazeby, Jane M., Birtle, Alison, Halliday, Alison et al.
(2018)
An observational study showed that explaining randomization using gambling-related metaphors and computer-agency descriptions impeded randomized clinical trial recruitment.
Journal of Clinical Epidemiology, 99
.
pp. 75-83.
doi:10.1016/j.jclinepi.2018.02.018
ISSN 0895-4356.
Stallard, Nigel and Kimani, Peter K. (2018) Uniformly minimum variance conditionally unbiased estimation in multi-arm multi-stage clinical trials. Biometrika, 105 (2). pp. 495-501. doi:10.1093/biomet/asy004 ISSN 1464-3510.
Miller, Frank, Zohar, Sarah, Stallard, Nigel, Madan, Jason, Posch, Martin, Hee, Siew Wan, Pearce , Michael, VΓ₯gerΓΆ, MΓ₯rten and Day, Simon (2018) Approaches to sample size calculation for clinical trials in rare diseases. Pharmaceutical Statistics, 17 (3). pp. 214-230. doi:10.1002/pst.1848 ISSN 1539-1604.
Mistry, Dipesh, Stallard, Nigel and Underwood, Martin (2018) A recursive partitioning approach for subgroup identification in individual patient data meta-analysis. Statistics in Medicine, 37 (9). pp. 1550-1561. doi:10.1002/sim.7609 ISSN 0277-6715.
Toumazi, A., Comets, E., Alberti, C., Friede, T., Lentz, F., Stallard, Nigel, Zohar, S. and Ursino, M. (2018) dfpk : An R-package for Bayesian dose-finding designs using Pharmacokinetics (PK) for phase I clinical trials. Computer Methods and Programs in Biomedicine, 157 . pp. 163-177. doi:10.1016/j.cmpb.2018.01.023 ISSN 0169-2607.
Sewell, Fiona, Ragan, Ian, Indans, Ian, Marczylo, Tim, Stallard, Nigel, Griffiths, David, Holmes, Thomas, Smith, Paul and Horgan, Graham (2018) An evaluation of the fixed concentration procedure for assessment of acute inhalation toxicity. Regulatory Toxicology and Pharmacology, 94 . pp. 22-32. doi:10.1016/j.yrtph.2018.01.001 ISSN 0273-2300.
Hee, Siew Wan, Parsons, Nicholas R. and Stallard, Nigel (2018) Decision-theoretic designs for a series of trials with correlated treatment effects using the Sarmanov multivariate beta-binomial distribution. Biometrical Journal, 60 (2). pp. 232-245. doi:10.1002/bimj.201600202 ISSN 0323-3847.
Pearce, Michael, Hee, Siew Wan, Madan, Jason, Posch, Martin, Day, Simon, Miller, Frank, Zohar, Sarah and Stallard, Nigel (2018) Value of information methods to design a clinical trial in a small population to optimise a health economic utility function. BMC Medical Research Methodology, 18 (1). p. 20. doi:10.1186/s12874-018-0475-0 ISSN 1471-2288.
Stallard, Nigel, Miller, Frank, Day, Simon, Hee, Siew Wan, Madan, Jason, Zohar, Sarah and Posch, Martin (2017) Determination of the optimal sample size for a clinical trial accounting for the population size. Biometrical Journal, 59 (4). pp. 609-625. doi:10.1002/bimj.201500228 ISSN 0323-3847.
Ursino, Moreno, Zohar, Sarah, Lentz, Frederike, Alberti, Corinne, Friede, Tim, Stallard, Nigel and Comets, Emmanuelle (2017) Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations. Biometrical Journal, 59 (4). pp. 804-825. doi:10.1002/bimj.201600084 ISSN 0323-3847.
Ellard, David R., Underwood, Martin, Achana, Felix A., Antrobus, James H. L., Balasubramanian, Shyam, Brown, Sally, Cairns, Melinda, Griffin, James M., Griffiths, Frances, Haywood, Kirstie L., Hutchinson, Charles E., Lall, Ranjit, Petrou, Stavros, Stallard, Nigel, Tysall, Colin, Walsh, David A. and Sandhu, Harbinder (2017) Facet joint injections for people with persistent non-specific low back pain (Facet Injection Study) : a feasibility study for a randomised controlled trial. Health Technology Assessment, 21 (30). pp. 1-184. doi:10.3310/hta21300 ISSN 1366-5278.
Robertson, Wendy, Fleming, Joanna, Kamal, Atiya, Hamborg, Thomas, Khan, Khalid Saeed, Griffiths, Frances, Stewart-Brown, Sarah L., Stallard, Nigel, Petrou, Stavros, Simkiss, Douglas E., Harrison, Elizabeth, Kim, S. W. and Thorogood, Margaret (2017) Randomised controlled trial and economic evaluation of the βFamilies for Healthβ programme to reduce obesity in children. Archives of Disease in Childhood, 102 (5). pp. 416-426. doi:10.1136/archdischild-2016-311514 ISSN 0003-9888.
Hee, Siew Wan, Willis, Adrian, Tudur Smith, Catrin, Day, Simon, Miller, Frank, Madan, Jason, Posch, Martin, Zohar, Sarah and Stallard, Nigel (2017) Does the low prevalence affect the sample size of interventional clinical trials of rare diseases? An analysis of data from the aggregate analysis of clinicaltrials.gov. Orphanet Journal of Rare Diseases, 12 (44). doi:10.1186/s13023-017-0597-1 ISSN 1750-1172.
Kunz, Cornelia, Stallard, Nigel, Parsons, Nicholas R., Todd, Susan and Friede, Tim (2017) Blinded versus unblinded estimation of a correlation coefficient to inform interim design adaptations. Biometrical Journal, 59 (2). pp. 344-357. doi:10.1002/bimj.201500233 ISSN 0323-3847.
Wason, James M. S., Stallard, Nigel, Bowden, Jack and Jennison, Christopher (2017) A multi-stage drop-the-losers design for multi-arm clinical trials. Statistical Methods in Medical Research , 26 (1). pp. 508-524. doi:10.1177/0962280214550759 ISSN 0962-2802.
Robertson, Wendy, Fleming, J, Kamal, Atiya, Hamborg , T, Khan, K. A., Griffiths, Frances, Stewart-Brown, Sarah L., Stallard, Nigel, Petrou, Stavros, Simkiss, Douglas E., Harrison, Elizabeth, Kim, S. W. and Thorogood, Margaret (2017) Randomised controlled trial evaluating the effectiveness and cost-effectiveness of 'Families for Health', a family-based childhood obesity treatment intervention delivered in a community setting for ages 6 to 11 years. Health Technology Assessment, 21 (1). doi:10.3310/hta21010 ISSN 1366-5278.
McAloon, Christopher, Boylan, Luke M., Hamborg, Thomas, Stallard, Nigel, Osman, Faizel, Lim, Phang B. and Hayat, Sajad A. (2016) The changing face of cardiovascular disease 2000β2012 : an analysis of the world health organisation global health estimates data. International Journal of Cardiology, 224 . pp. 256-264. doi:10.1016/j.ijcard.2016.09.026 ISSN 0167-5273.
Perkins, Gavin D., Quinn, Tom, Deakin, Charles D., Nolan, Jerry, Lall, Ranjit, Slowther, Anne, Cooke, Matthew, Lamb, S. E. (Sallie E.), Petrou, Stavros, Achana, Felix A. et al.
(2016)
Pre-hospital assessment of the role of adrenaline : measuring the effectiveness of drug administration in cardiac arrest (PARAMEDIC-2) : Trial protocol.
Resuscitation, 108
.
pp. 75-81.
doi:10.1016/j.resuscitation.2016.08.029
ISSN 0300-9572.
Ondra, Thomas, JobjΓΆrnsson, Sebastian, Beckman, Robert A., Burman, Carl-Fredrik, KΓΆnig, Franz, Stallard, Nigel and Posch, Martin (2016) Optimizing trial designs for targeted therapies. PLoS One, 11 (9). e0163726. doi:10.1371/journal.pone.0163726 ISSN 1932-6203.
Patel, Shilpa, Hee, Siew Wan, Mistry, Dipesh, Jordan, Jake, Brown, S., Dritsaki, Melina, Ellard, David R., Friede, Tim, Lamb, S. E., Lord, Joanne, Madan, Jason, Morris, Tom, Stallard, Nigel, Tysall, Colin, Willis, Adrian and Underwood, Martin (2016) Identifying back pain subgroups : developing and applying approaches using individual patient data collected within clinical trials. Programme Grants for Applied Research, 4 (10). doi:10.3310/pgfar04100 ISSN 2050-4322.
Hilgers, Ralf-Dieter, Roes, Kit and Stallard, Nigel (2016) Directions for new developments on statistical design and analysis of small population group trials. Orphanet Journal of Rare Diseases, 11 (1). 78. doi:10.1186/s13023-016-0464-5 ISSN 1750-1172.
Hee, Siew Wan, Hamborg, Thomas, Day, Simon, Madan, Jason, Miller, F., Posch, Martin, Zohar, Sarah and Stallard, Nigel (2016) Decision-theoretic designs for small trials and pilot studies : a review. Statistical methods in medical research, 25 (3). pp. 1022-1038. doi:10.1177/0962280215588245 ISSN 0962-2802.
Taylor-Phillips, Sian, Wallis, Matthew G., Jenkinson, David J., Adekanmbi, Victor, Parsons, Helen, Dunn, Janet A., Stallard, Nigel, Szczepura, Ala, Gates, Simon, Kearins, Olive, Duncan, Alison, Hudson, Sue and Clarke, Aileen (2016) Effect of using the same vs different order for second readings of screening mammograms on rates of breast cancer detection : a randomized clinical trial. JAMA: The Journal of the American Medical Association, 315 (18). pp. 1956-1965. doi:10.1001/jama.2016.5257 ISSN 0098-7484.
Price, Charlotte L, Brace-McDonnell, Samantha J., Stallard, Nigel, Bleetman, Anthony, Maconochie, I. and Perkins, Gavin D. (2016) Performance characteristics of five triage tools for major incidents involving traumatic injuries to children. Injury, 47 (5). pp. 988-992. doi:10.1016/j.injury.2015.10.076 ISSN 0020-1383.
Unkel, Steffen, RΓΆver, Christian, Stallard, Nigel, Benda, Norbert, Posch, Martin, Zohar, Sarah and Friede, Tim (2016) Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions. Orphanet Journal of Rare Diseases, 11 (1). 16. doi:10.1186/s13023-016-0402-6 ISSN 1750-1172.
Stein, Robert C., Dunn, Janet A., Bartlett, John M. S., Campbell, Amy, Marshall, A. (Andrea)β, Hall, Peter, Rooshenas, Leila, Morgan, Adrienne, Poole, Christopher, Pinder, Sarah E., Cameron, David A., Stallard, Nigel, Donovan, Jenny L., McCabe, Christopher, Hughes-Davies, Luke and Makris, Andreas (2016) R : OPTIMA prelim : a randomised feasibility study of personalised care in the treatment of women with early breast cancer. Health Technology Assessment, 20 (10). pp. 1-202. doi:10.3310/hta20100 ISSN 1366-5278.
Ondra, Thomas, Dmitrienko, Alex, Friede, Tim, Graf, Alexandra, Miller, F. (Frank), Stallard, Nigel and Posch, Martin (2016) Methods for identification and confirmation of targeted subgroups in clinical trials : a systematic review. Journal of Biopharmaceutical Statistics, 26 (1). pp. 99-119. ISSN 1054-3406.
Sandhu, Harbinder, Ellard, David R., Achana, Felix A., Antrobus, James H. L., Balasubramanian, Shyam, Brown, Sally, Cairns, Melinda, Griffiths, Frances, Haywood, Kirstie L., Hutchinson, Charles E., Lall, Ranjit, Petrou, Stavros, Stallard, Nigel, Tysall, Colin, Walsh, David A. and Underwood, Martin (2015) Facet-joint injections for people with persistent non-specific low back pain (FIS) : study protocol for a randomised controlled feasibility trial. Trials, 16 (1). doi:10.1186/s13063-015-1117-z ISSN 1745-6215.
Couper, Keith, Kimani, Peter K., Abella, Benjamin S., Chilwan, Mehboob, Cooke, Matthew, Davies, Robin P., Field, Richard A., Smith, F. Gao (Fang Gao), Quinton, Sarah, Stallard, Nigel, Woolley, Sarah and Perkins, Gavin D. (2015) The system-wide effect of real-time audiovisual feedback and postevent debriefing for in-hospital cardiac arrest. Critical Care Medicine, 43 (11). pp. 2321-2331. doi:10.1097/CCM.0000000000001202 ISSN 0090-3493.
Stallard, Nigel, Kunz, Cornelia, Todd, Susan, Parsons, Nicholas R. and Friede, Tim (2015) Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial. Statistics in Medicine, 34 (23). pp. 3104-3115. doi:10.1002/sim.6567 ISSN 0277-6715.
Kimani, Peter K., Todd, Susan and Stallard, Nigel (2015) Estimation after subpopulation selection in adaptive seamless trials. Statistics in Medicine, 34 (18). pp. 2581-2601. doi:10.1002/sim.6506 ISSN 0277-6715.
Morris, Tom, Hee, Siew Wan, Stallard, Nigel, Underwood, Martin and Patel, Shilpa (2015) Can we convert between outcome measures of disability for chronic low back pain? Spine, 40 (10). pp. 734-739. doi:10.1097/BRS.0000000000000866 ISSN 0362-2436.
Williams, Stefanie L., Michie, Susan, Dale, Jeremy, Stallard, Nigel and French, David P. (2015) The effects of a brief intervention to promote walking on Theory of Planned Behavior constructs : a cluster randomized controlled trial in general practice. Patient Education and Counseling, 98 (5). pp. 651-659. doi:10.1016/j.pec.2015.01.010 ISSN 0738-3991.
Kunz, Cornelia, Friede, Tim, Parsons, Nicholas R., Todd, Susan and Stallard, Nigel (2015) A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints. Journal of Biopharmaceutical Statistics, 25 (1). pp. 170-189. doi:10.1080/10543406.2013.840646 ISSN 1054-3406.
Kunz, Cornelia, Friede, Tim, Parsons, Nicholas R., Todd, Susan and Stallard, Nigel (2014) Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data. Pharmaceutical Statistics, Volume 13 (Number 4). pp. 238-246. doi:10.1002/pst.1619 ISSN 1539-1604.
Magirr, Dominic, Stallard, Nigel and Jaki, Thomas (2014) Flexible sequential designs for multi-arm clinical trials. Statistics in Medicine, 33 (19). pp. 3269-3279. doi:10.1002/sim.6183 ISSN 0277-6715.
Couper, Keith, Kimani, Peter K., Chilwan, Mehboob, Cooke, Matthew, Davies, Robin P., Field, Richard A., Smith, F. Gao (Fang Gao), Quinton, Sarah, Stallard, Nigel and Perkins, Gavin D. (2014) The impact of real-time audiovisual feedback and post-event debriefing : the CPR quality improvement initiative. Resuscitation, 85 (1). s7. doi:10.1016/j.resuscitation.2014.03.027 ISSN 0300-9572.
Mistry, Dipesh, Patel, Shilpa, Hee, Siew Wan, Stallard, Nigel and Underwood, Martin (2014) Evaluating the quality of subgroup analyses in randomized controlled trials of therapist delivered interventions for non-specific low back pain : a systematic review. Spine, 39 (7). pp. 618-629. doi:10.1097/BRS.0000000000000231 ISSN 0362-2436.
Szczepura, Ala, Manzoor, Susan, Hardy, K. (Katherine), Stallard, Nigel, Parsons, Helen, Gossain, Savita and Hawkey, P. M. (Peter M.) (2014) How do hospital professionals involved in a randomised controlled trial perceive the value of genotyping vs. PCR-ribotyping for control of hospital acquired C. difficile infections? BMC Infectious Diseases, Volume 14 (Number 1). Article number 154. doi:10.1186/1471-2334-14-154 ISSN 1471-2334.
Wason, J., Marshall, A. (Andrea)β, Dunn, Janet A., Stein, R. C. and Stallard, Nigel (2014) Adaptive designs for clinical trials assessing biomarker-guided treatment strategies. British Journal of Cancer, Volume 110 (Number 8). pp. 1950-1957. doi:10.1038/bjc.2014.156 ISSN 0007-0920.
Taylor-Phillips, Sian, Wallis, Matthew G., Parsons, Helen, Dunn, Janet A., Stallard, Nigel, Campbell, Helen, Sellars, Sarah, Szczepura, Ala, Gates, Simon and Clarke, Aileen (2014) Changing case order to optimise patterns of performance in mammography screening (CO-OPS) : study protocol for a randomized controlled trial. Trials, Volume 15 . Article number 17. doi:10.1186/1745-6215-15-17 ISSN 1745-6215.
Kimani, Peter K., Todd, Susan and Stallard, Nigel (2014) A comparison of methods for constructing confidence intervals after phase II/III clinical trials. Biometrical Journal, Volume 56 (Number 1). pp. 107-128. doi:10.1002/bimj.201300036 ISSN 0323-3847.
Stallard, Nigel, Hamborg, Thomas, Parsons, Nicholas R. and Friede, Tim (2014) Adaptive designs for confirmatory clinical trials with subgroup selection. Journal of Biopharmaceutical Statistics, Volume 24 (Number 1). pp. 168-187. doi:10.1080/10543406.2013.857238 ISSN 1054-3406.
Minas, Giorgos, Aston, John A. D. and Stallard, Nigel (2014) Adaptive multivariate global testing. Journal of the American Statistical Association, Volume 109 (Number 506). doi:10.1080/01621459.2013.870905 ISSN 0162-1459.
Barker, Karen, MSc, Javaid, Muhammad K., Newman, Meredith, Lowe, Catherine Minns, Stallard, Nigel, Campbell, Helen, Gandhi, Varsha and Lamb, S. E. (Sallie E.) (2014) Physiotherapy rehabilitation for osteoporotic vertebral fracture (PROVE) : study protocol for a randomised controlled trial. Trials, Volume 15 (Number 1). Article Number 22. doi:10.1186/1745-6215-15-22 ISSN 1745-6215.
Simkiss, Douglas E., Stallard, Nigel and Thorogood, Margaret (2013) A systematic literature review of the factors associated with children entering public care. Child: Care, Health and Development, 39 (5). pp. 628-642. ISSN 0305-1862.
Simkiss, Douglas E., Stallard, Nigel and Thorogood, Margaret (2013) A systematic review of the risk factors associated with children entering public care. Child: Care, Health and Development, Volume 39 (Number 5). pp. 628-642. doi:10.1111/cch.12010 ISSN 0305-1862.
Simkiss, Douglas E., Snooks, Helen, Stallard, Nigel, Kimani, Peter K., Sewell, Bernadette, Fitzsimmons, Deborah, Anthony, Rebecca, Winstanley, Sarah, Wilson, Lynsey, Phillips, Ceri and Stewart-Brown, Sarah L. (2013) Effectiveness and cost-effectiveness of a universal parenting skills programme in deprived communities : multicentre randomised controlled trial. BMJ Open, Volume 3 (Number 8). Article number 002851. doi:10.1136/bmjopen-2013-002851 ISSN 2044-6055.
Kimani, Peter K., Todd, Susan C. and Stallard, Nigel (2013) Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility. Statistics in Medicine, Volume 32 (Number 17). pp. 2893-2901. doi:10.1002/sim.5757 ISSN 0277-6715.
Bartlett, J., Canney, P., Campbell, A. M., Cameron, D., Donovan, Jenny, Dunn, Janet A., Earl, Helena M., Francis, A., Hall, P., Harmer, V. et al.
(2013)
Selecting breast cancer patients for chemotherapy : the opening of the UK OPTIMA trial.
Clinical Oncology, Volume 25
(Number 2).
pp. 109-116.
doi:10.1016/j.clon.2012.10.005
ISSN 0936-6555.
Friede, Tim, Parsons, Nicholas R. and Stallard, Nigel (2013) Correction : A conditional error function approach for subgroup selection in adaptive clinical trials. Statistics in Medicine, Volume 32 (Number 14). pp. 2513-2514. doi:10.1002/sim.5759 ISSN 0277-6715.
Robertson, Wendy, Stewart-Brown, Sarah L., Stallard, Nigel, Petrou, Stavros, Griffiths, Frances, Thorogood, Margaret, Simkiss, Douglas E., Lang, R. (Rebecca), Reddington, Kate, Poole, Francine, Rye, G. (Gloria), Khan, Kamran, Hamborg, Thomas and Kirby, J. (Joanna) (2013) Evaluation of the effectiveness and cost-effectiveness of Families for Health V2 for the treatment of childhood obesity : study protocol for a randomized controlled trial. Trials, Volume 14 (Number 1). Article : 81. doi:10.1186/1745-6215-14-81 ISSN 1745-6215.
Wason, James M. S., Jaki, Thomas and Stallard, Nigel (2013) Planning multi-arm screening studies within the context of a drug development program. Statistics in Medicine, Volume 32 (Number 20). pp. 3424-3435. doi:10.1002/sim.5787 ISSN 0277-6715.
Powell, John, Hamborg, Thomas, Stallard, Nigel, Burls, Amanda, McSorley, Jaime, Bennett, Kylie, Griffiths, Kathleen M and Christensen, Helen (2012) Effectiveness of a web-based cognitive-behavioral tool to improve mental well-being in the general population : randomized controlled trial. Journal of Medical Internet Research, 15 (1). e2. doi:10.2196/jmir.2240 ISSN 1438-8871.
Stallard, Nigel (2012) Optimal sample sizes for phase II clinical trials and pilot studies. Statistics in Medicine, Vol.31 (No.11-12). pp. 1031-1042. doi:10.1002/sim.4357 ISSN 0277-6715.
Parsons, Nicholas R., Friede, Tim, Todd, S., Marquez, Elsa Valdes, Chataway, J., Nicholas, Richard and Stallard, Nigel (2012) An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection. Computational Statistics & Data Analysis, Vol.56 (No.5). pp. 1150-1160. doi:10.1016/j.csda.2010.10.027 ISSN 0167-9473.
Simkiss, Douglas E., Spencer, Nick, Stallard, Nigel and Thorogood, Margaret (2012) Health service use in families where children enter public care : a nested case control study using the General Practice Research Database. BMC Health Services Research, Vol.12 (No.1). p. 65. doi:10.1186/1472-6963-12-65 ISSN 1472-6963.
Minas, Giorgos, Rigat, Fabio, Nichols, Thomas E., Aston, John A. D. and Stallard, Nigel (2012) A hybrid procedure for detecting global treatment effects in multivariate clinical trials : theory and applications to fMRI studies. Statistics in Medicine, Vol.31 (No.3). pp. 253-268. doi:10.1002/sim.4395 ISSN 0277-6715.
Hee, Siew Wan and Stallard, Nigel (2012) Designing a series of decision-theoretic phase II trials in a small population. Statistics in Medicine, Vol.31 (No.30). pp. 4337-4351. doi:10.1002/sim.5573 ISSN 0277-6715.
Perkins, Gavin D., Kimani, Peter K., Bullock, Ian, Clutton-Brock, T., Davies, R. P, Gale, M., Lam, J., Lockey, A. and Stallard, Nigel (2012) Improving the efficiency of advanced life support training : a randomized, controlled trial. Annals of Internal Medicine, Volume 157 (Number 1). pp. 19-28. doi:10.7326/0003-4819-157-1-201207030-00005 ISSN 0003-4819.
Kimani, Peter K., Glimm, Ekkehard, Maurer, Willi, Hutton, Jane and Stallard, Nigel (2012) Practical guidelines for adaptive seamless phase II/III clinical trials that use Bayesian methods. Statistics in Medicine, Vol.31 (No.19). pp. 2068-2085. doi:10.1002/sim.5326 ISSN 0277-6715.
Hardy, K. (Katherine), Manzoor, Susan, Marriott, C., Parsons, Helen, Waddington, C., Gossain, Savita, Szczepura, Ala, Stallard, Nigel and Hawkey, P. M. (Peter M.) (2012) Utilizing rapid multiple-locus variable-number tandem-repeat analysis typing to aid control of hospital-acquired clostridium difficile infection : a multicenter study. Journal of Clinical Microbiology, Vol.50 (No.10). pp. 3244-3248. doi:10.1128/JCM.00784-12 ISSN 0095-1137.
ICCD Study Group (Including: Armstrong, Natalie, Baines, Darrin L., Baker, Richard H., Crossman, Richard, Davies, Melanie, Hardy, Ainsley, Khunti, Kamlesh, Kumar, Sudhesh, O'Hare, J. Paul, Raymond, Neil T., Saravanan, Ponnusamy, Stallard, Nigel, Szczepura, Ala and Wilson, Andrew). (2012) A cluster randomized controlled trial of the effectiveness and cost-effectiveness of Intermediate Care Clinics for Diabetes (ICCD) : study protocol for a randomized controlled trial. Trials, Vol.13 (No.1). p. 164. doi:10.1186/1745-6215-13-164 ISSN 1745-6215.
Friede, Tim, Parsons, Nicholas R. and Stallard, Nigel (2012) A conditional error function approach for subgroup selection in adaptive clinical trials. Statistics in Medicine, Vol.31 (No.30). pp. 4309-4320. doi:10.1002/sim.5541 ISSN 0277-6715.
Stallard, Nigel (2011) An adaptive seamless phase II/III clinical trial design incorporating short-term endpoint information. Trials, Vol.12 (Suppl.1). A2. doi:10.1186/1745-6215-12-S1-A2 ISSN 1745-6215.
Stallard, Nigel and Todd, S. (2011) Seamless phase II/III designs. Statistical Methods in Medical Research , Vol.20 (No.6). pp. 623-634. doi:10.1177/0962280210379035 ISSN 0962-2802.
Perkins, Gavin D., Davies, Robin P., Quinton, Sarah, Woolley, Sarah, Smith, F. Gao (Fang Gao), Abella, Benjamin S., Stallard, Nigel and Cooke, Matthew (Professor of clinical systems design) (2011) The effect of real-time CPR feedback and post event debriefing on patient and processes focused outcomes : a cohort study : trial protocol. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, Vol.19 (No.1). p. 58. doi:10.1186/1757-7241-19-58 ISSN 1757-7241.
Perkins, Gavin D., Davies, Robin P., Quinton, Sarah, Woolley, Sarah, Gao, F., Abella, Benjamin S., Stallard, Nigel and Cooke, Matthew (Professor of clinical systems design) (2011) The effect of real-time CPR feedback and post event debriefing on patient and processes focused outcomes : A cohort study: trial protocol. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 19 (1). p. 58. doi:10.1186/1757-7241-19-58 ISSN 1757-7241 .
French, David, Williams, Stefanie L., Michie, Susan, Taylor, Claire, Szczepura, Ala, Stallard, Nigel and Dale, Jeremy (2011) A cluster randomised controlled trial of the efficacy of a brief walking intervention delivered in primary care : study protocol. BMC Family Practice, Vol.12 (No.1). p. 56. doi:10.1186/1471-2296-12-56 ISSN 1471-2296.
Friede, Tim, Parsons, Nicholas R., Stallard, Nigel, Todd, S. (Susan), Valdes Marquez, E., Chataway, Jeremy and Nicholas, R. (Richard) (2011) Designing a seamless phase II/III clinical trial using early outcomes for treatment selection : an application in multiple sclerosis. Statistics in Medicine, Vol.30 (No.13). pp. 1528-1540. doi:10.1002/sim.4202 ISSN 02776715.
Kilner, T. M., Brace, Samantha J., Cooke, Matthew (Professor of clinical systems design), Stallard, Nigel, Bleetman, A. and Perkins, Gavin D. (2011) In βbig bangβ major incidents do triage tools accurately predict clinical priority? : a systematic review of the literature. Injury, Vol.42 (No.5). pp. 460-468. doi:10.1016/j.injury.2010.11.005 ISSN 0020-1383.
Stallard, Nigel, Price, Charlotte L, Creton, Stuart, Indans, Ian, Guest, Robert, Griffiths, David and Edwards, Philippa (2011) A new sighting study for the fixed concentration procedure to allow for gender differences. Human & Experimental Toxicology, Vol.30 (No.3). pp. 239-249. doi:10.1177/0960327110370983 ISSN 0960-3271.
Price, Charlotte L, Stallard, Nigel, Creton, Stuart, Indans, Ian, Guest, Robert, Griffiths, David and Edwards, Philippa (2011) A statistical evaluation of the effects of gender differences in assessment of acute inhalation toxicity. Human & Experimental Toxicology, Vol.30 (No.3). pp. 217-238. doi:10.1177/0960327110370982 ISSN 0960-3271.
Leung, Edmund, Ferjani, Ali M., Kitchen, Andrew, Griffin, Damian R., Stallard, Nigel and Wong, Ling S. (2011) Risk-adjusted scoring systems can predict surgeonsβ performance in colorectal surgery. Surgeon, Vol.9 (No.1). pp. 3-7. doi:10.1016/j.surge.2010.07.008 ISSN 1479666X.
Chataway, J., Nicholas, R., Todd, S., Miller, D. H., Parsons, Nicholas R., Valdes-Marquez, E., Stallard, Nigel and Friede, Tim (2011) A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis. Multiple Sclerosis Journal, Vol.17 (No.1). pp. 81-88. doi:10.1177/1352458510382129 ISSN 1352-4585.
Davies, Robin P., Lam, Jenny, Bullock, Ian, Clutton-Broch, Tom, Gales, Mike, Lockey, Andrew, Kimani, Peter K., Stallard, Nigel and Perkins, Gavin D. (2011) Blended advanced life support training : a randomized controlled noninferiority trial. Circulation, Vol. 124 . ISSN 1524-4539.
Stallard, Nigel (2011) Group-sequential methods for adaptive seamless phase II/III clinical trials. Journal of Biopharmaceutical Statistics, Vol.21 (No.4). pp. 787-801. doi:10.1080/10543406.2011.551335 ISSN 1054-3406.
Stewart-Brown, Sarah L., Anthony, Rebecca, Wilson, Lynsey, Winstanley, Sarah, Stallard, Nigel, Snooks, Helen and Simkiss, Douglas E. (2011) Should randomised controlled trials be the "gold standard" for research on preventive interventions for children? Journal of Children's Services, Vol.6 (No.4). pp. 228-235. doi:10.1108/17466661111190929 ISSN 1746-6660.
Friede, Tim, Nicholas, Richard, Stallard, Nigel, Todd, Susan, Parsons, Nicholas R., Valdes-Marquez, Elsa and Chataway, J. (2010) Refinement of the clinical scenario evaluation framework for assessment of competing development strategies with an application to multiple sclerosis. Drug Information Journal, Vol.44 (No.6). pp. 713-718. doi:10.1177/009286151004400607 ISSN 0092-8615.
Simkiss, Douglas E., Snooks, Helen, Stallard, Nigel, Davies, Shan, Thomas, Marie A., Anthony, Becky, Winstanley, Sarah, Wilson, Lynsey and Stewart-Brown, Sarah L. (2010) Measuring the impact and costs of a universal group based parenting programme : protocol and implementation of a trial. BMC Public Health, Vol.10 . Article 364. doi:10.1186/1471-2458-10-364 ISSN 1471-2458.
Stallard, Nigel (2010) A confirmatory seamless phase II/III clinical trial design incorporating short-term endpoint information. Statistics in Medicine, Vol.29 (No.9). pp. 959-971. doi:10.1002/sim.3863 ISSN 0277-6715.
Brannath, Werner, Burger, Hans Ulrich, Glimm, Ekkehard, Stallard, Nigel, Vandemeulebroecke, Marc and Wassmer, Gernot (2010) Comments on the draft guidance on βAdaptive design clinical trials for drugs and biologicsβ of the U.S. Food and Drug Administration. Journal of Biopharmaceutical Statistics, Vol.20 (No.6). pp. 1125-1131. doi:10.1080/10543406.2010.514453 ISSN 1054-3406.
Leung, Edmund, Ferjani, Ali M., Stallard, Nigel and Wong, Ling S. (2009) Predicting post-operative mortality in patients undergoing colorectal surgery using P-POSSUM and CR-POSSUM scores : a prospective study. International Journal of Colorectal Disease, Vol.24 (No.12). pp. 1459-1464. doi:10.1007/s00384-009-0781-4 ISSN 0179-1958.
Whitehead, John, Kelly, P. J., Zhou, Yinghui, Stallard, Nigel, Thygesen, Helene and Bowman, Clive (2009) Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme. Pharmaceutical Statistics, Vol.8 (No.4). pp. 287-300. doi:10.1002/pst.357 ISSN 1539-1604.
Chataway, J., Nicholas, R., Todd, S., Stallard, Nigel, Valdes-Marquez, E., Parsons, Nicholas R. and Friede, Tim (2009) FP36-WE-01 Adaptive seamless trial designs in neurology : a case study in secondary progressive multiple sclerosis. Journal of the Neurological Sciences, Vol.285 (Supp.1). S113-S114. doi:10.1016/S0022-510X(09)70456-3 ISSN 0022-510X.
Hardy, K. (Katherine), Price, Charlotte L, Szczepura, Ala, Gossain, Savita, Davies, Ruth, Stallard, Nigel, Shabir, Sahida, McMurray, Claire, Bradbury, Andrew and Hawkey, P. M. (Peter M.) (2009) Reduction in the rate of methicillin-resistant Staphylococcus aureus acquisition in surgical wards by rapid screening for colonization : a prospective, cross-over study. Clinical Microbiology and Infection, Vol.16 (No.4). pp. 333-339. doi:10.1111/j.1469-0691.2009.02899.x ISSN 1198-743X.
Sandhu, Harbinder, Dale, Jeremy, Stallard, Nigel, Crouch, R. and Glucksman, E. (2009) Emergency nurse practitioners and doctors consulting with patients in an emergency department : a comparison of communication skills and satisfaction. Emergency Medicine Journal, Vol.26 (No.6). pp. 400-404. doi:10.1136/emj.2008.058917 ISSN 1472-0205.
Stallard, Nigel, Posch, Martin, Friede, Tim, Koenig, F. (Franz) and Brannath, Werner (2009) Optimal choice of the number of treatments to be included in a clinical trial. Statistics in Medicine, Vol.28 (No.9). pp. 1321-1338. doi:10.1002/sim.3551 ISSN 0277-6715.
Kimani, Peter K., Stallard, Nigel and Hutton, Jane (2009) Dose selection in seamless phase II/III clinical trials based on efficacy and safety. Statistics in Medicine, Vol.28 (No.6). pp. 917-936. doi:10.1002/sim.3522 ISSN 0277-6715.
Stallard, Nigel (2009) Simple tests for the external validation of mortality prediction scores. Statistics in Medicine, Vol.28 (No.3). pp. 377-388. doi:10.1002/sim.3393 ISSN 0277-6715.
Parsons, Nicholas R., Costa, Matthew L., Achten, Juul and Stallard, Nigel (2009) Repeated measures proportional odds logistic regression analysis of ordinal score data in the statistical software package R. Computational Statistics & Data Analysis, Vol.53 (No.3). pp. 632-641. doi:10.1016/j.csda.2008.08.004 ISSN 0167-9473.
Chataway, J., Nicholas, R., Todd, S., Stallard, Nigel, Valdes-Marquez, E., Parsons, Nicholas R. and Friede, Tim (2009) Adaptive seamless trial designs in neurology : a case study in secondary progressive multiple sclerosis [Abstract]. Journal of the Neurological Sciences, Vol.285 (Suppl.1). S113-S114. doi:10.1016/S0022-510X(09)70456-3 ISSN 0022-510X.
Stallard, Nigel and Friede, Tim (2008) A group-sequential design for clinical trials with treatment selection. Statistics in Medicine, Vol.27 (No.29). pp. 6209-6227. doi:10.1002/sim.3436 ISSN 0277-6715.
Stallard, Nigel and Cockey, Louise (2008) Two-stage designs for phase II cancer trials with ordinal responses. Contemporary Clinical Trials, Vol.29 (No.6). pp. 896-904. doi:10.1016/j.cct.2008.07.003 ISSN 1551-7144.
Friede, Tim and Stallard, Nigel (2008) A comparison of methods for adaptive treatment selection. Biometrical Journal, Vol.50 (No.5 Sp. Iss. SI). pp. 767-781. doi:10.1002/bimj.200710453 ISSN 0323-3847.
Goodyear, S. J., Stallard, Nigel, Gaunt, Anne, Parker, R. (Ron), Williams, N. and Wong, L. (2008) Local impact of the English arm of the UK bowel cancer screening pilot study. British Journal of Surgery, Vol.95 (No.9). pp. 1172-1179. doi:10.1002/bjs.6230 ISSN 0007-1323.
Marzanski, Marek, Jainer, Ashok Kumar and Stallard, Nigel (2008) Naturalistic study of the efficacy of different treatment strategies in relapse prevention in bipolar affective disorders. International Medical Journal, Vol.15 (No.4). pp. 277-285. ISSN 1341-2051.
Stallard, Nigel, Todd, S. and Whitehead, John (2008) Estimation following selection of the largest of two normal means. Journal of Statistical Planning and Inference, Vol.138 (No.6). pp. 1629-1638. doi:10.1016/j.jspi.2007.05.045 ISSN 0378-3758.
Kandala, Ngianga-Bakwin, Ji, Chen, Stallard, Nigel, Stranges, Saverio and Cappuccio, Francesco (2008) Morbidity from diarrhoea, cough and fever among young children in Nigeria. Annals of Tropical Medicine & Parasitology, Vol.102 (No.5). pp. 427-445. doi:10.1179/136485908X300797 ISSN 0003-4983.
Waylen, Andrea, Stallard, Nigel and Stewart-Brown, Sarah L. (2008) Parenting and health in mid-childhood : a longitudinal study. European Journal of Public Health, Vol.18 (No.3). pp. 300-305. doi:10.1093/eurpub/ckm131 ISSN 1101-1262.
Kelly, Patrick, Zhou, Yinghui, Whitehead, John, Stallard, Nigel and Bowman, Clive (2008) Sequentially testing for a gene-drug interaction in a genomewide analysis. Statistics in Medicine, Vol.27 (No.11). pp. 2022-2034. doi:10.1002/sim.3059 ISSN 0277-6715.
Perkins, Gavin D., Davies, Robin P., Stallard, Nigel, Bullock, Ian, Stevens, Harry and Lockey, Andrew (2007) Advanced life support cardiac arrest scenario test evaluation. Resuscitation, 75 (3). pp. 484-490. doi:10.1016/j.resuscitation.2007.05.020 ISSN 0300-9572.
Hardy, K. (Katherine), Szczepura, Ala, Davies, Ruth, Bradbury, Andrew, Stallard, Nigel, Gossain, Savita, Walley, Paul and Hawkey, P. M. (Peter M.) (2007) A study of the efficacy and cost-effectiveness of MRSA screening and monitoring on surgical wards using a new, rapid molecular test (EMMS). BMC Health Services Research, Vol.7 (No.160). doi:10.1186/1472-6963-7-160 ISSN 1472-6963.
Ferjani, A. M., Griffin, Damian R., Stallard, Nigel and Wong, L. S. (2007) A newly devised scoring system for prediction of mortality in patients with colorectal cancer : a prospective study. Lancet Oncology, 8 (4). pp. 317-322. doi:10.1016/S1470-2045(07)70045-1 ISSN 1470-2045.
Kandala, Ngianga-Bakwin, Ji, Chen, Stallard, Nigel, Stranges, Saverio and Cappuccio, Francesco (2007) Spatial analysis of risk factors for childhood morbidity in Nigeria. American Journal of Tropical Medicine and Hygiene, Vol.77 (No.4). pp. 770-779. ISSN 0002-9637.
Belsky, Jay, Bell, Brian, Bradley, Robert H., Stallard, Nigel and Stewart-Brown, Sarah L. (2006) Socioeconomic risk, parenting during the preschool years and child health age 6 years. European Journal of Public Health, Vol.17 (No.5). pp. 508-513. doi:10.1093/eurpub/ckl261 ISSN 1101-1262.
Kelly, Patrick, Stallard, Nigel, Zhou, Yinghui, Whitehead, John and Bowman, Clive (2006) Sequential genome-wide association studies for monitoring adverse events in the clinical evaluation of new drugs. Statistics in Medicine, Vol.25 (No.18). pp. 3081-3092. doi:10.1002/sim.2499 ISSN 0277-6715.
Verzilli, Claudio J., Stallard, Nigel and Whittaker, John C. (2006) Bayesian graphical models for genomewide association studies. American Journal of Human Genetics, Volume 79 (Number 1). pp. 100-112. doi:10.1086/505313 ISSN 0002-9297.
Book Item
Stallard, Nigel (2011) Decision theory. In: Everitt, Brian S. and Palmer, Christopher R., (eds.) Encyclopaedic companion to medical statistics. Chichester, West Sussex, U.K.: John Wiley & Sons. ISBN 9780470684191
Stallard, Nigel and Friede, Tim (2011) Efficiency of adaptive designs. In: Pong, Annpey and Chow, Shein-Chung, (eds.) Handbook of adaptive designs in pharmaceutical and clinical development. Boca Raton: CRC Press. ISBN 9781439810163
Stallard, Nigel (2011) Sequential analysis. In: Everitt, Brian S. and Palmer, Christopher R., (eds.) Encyclopaedic companion to medical statistics. Chichester, West Sussex, U.K.: John Wiley & Sons. ISBN 9780470684191
Stallard, Nigel and Todd, S. (2009) Monitoring. In: Gad, Shayne Cox, (ed.) Clinical trials handbook. Hoboken, N.J.: Wiley, pp. 1019-1042. ISBN 9780471213888
Friede, Tim, Dunn, Janet A. and Stallard, Nigel (2008) Clinical trials in oncology. In: Missailidis, Sotiris, (ed.) Anticancer therapeutics. Oxford ; Hoboken, NJ: Wiley-Blackwell, pp. 365-375. ISBN 9780470723036
Stallard, Nigel (2008) Phase II clinical trials. In: Biswas, A. and Datta, S. and Fine, J. P. and Segal, M. R., (eds.) Statistical advances in the biomedical sciences : clinical trials, epidemiology, survival analysis, and bioinformatics. Wiley series in probability and statistics . Hoboken, N.J.: Wiley-Interscience, pp. 15-32. ISBN 9780471947530
Stallard, Nigel and Todd, Susan (2007) Statistical methods for combining clinical trial phases II and III. In: Auget, J. L. and Balakrishnan, N. and Mesbah, M. and Molenberghs, G., (eds.) Advances in Statistical Methods for the Health Sciences : Applications to Cancer and AIDS Studies, Genome Sequence Analysis, and Survival Analysis. Statistics for Industry and Technology, Part VII . BirkhΓ€user Boston, pp. 401-417. ISBN 9780817643683
Conference Item
Underwood, Martin, Antrobus, James H. L., Barkan, Kerry, Cairns, M., Ellard, David R., Griffiths, Frances, Haywood, Kirstie L., Keohane, S., Lega, C., Mars, Tom S., Sandhu, Harbinder and Stallard, Nigel (2014) Facet-joint injections for people with persistent non-specific low back pain (FIS). In: Facet Injection Study Consensus Conference (FISCC), University of Warwick, UK, 27 Jun 2014
Chataway, J., Nicholas, R., Stallard, Nigel, Todd, S., Parsons, Nicholas R., Valdes-Marquez, E. and Friede, Tim (2009) Developing a new trial design in secondary progressive multiple sclerosis: a seamless adaptive approach. In: ABN Joint Annual Meeting with the Spanish Society of Neurology, Liverpool, England, June 22-26, 2009. Published in: Journal of Neurology Neurosurgery and Psychiatry , Vol.80 (No.11). Article no. e3, p. 10. doi:10.1136/jnnp.2009.191775 ISSN 0022-3050.
Chataway, J., Nicholas, R., Todd, S., Stallard, Nigel, Valdes-Marquez, E., Parsons, Nicholas R. and Friede, Tim (2009) Adaptive seamless trial designs in neurology: a case study in secondary progressive multiple sclerosis. In: 19th World Congress of Neurology, Bangkok, Thailand, October 24-30, 2009. Published in: Journal of the Neurological Sciences, Vol.285 (Suppl. 1). S113-S114. doi:10.1016/S0022-510X(09)70456-3 ISSN 0022-510X.
Nicholas, R. (Richard), Chataway, Jeremy, Todd, S. C. (Susan C.), Stallard, Nigel, ValdΓ©s-MΓ‘rquez, Elsa, Parsons, Nicholas R. and Friede, Tim (2009) Adaptive clinical trials incorporating treatment selection and evaluation: methodology and application in progressive multiple sclerosis. In: 25th Congress of the European Committee for Treatment and Research in Multiple Sclerosis, DΓΌsseldorf, Germany, 9-12th September 2009
Journal Item
Stein, R. C., Makris, A., Hughes-Davies, L., Macpherson, I. R., Hall, P. S., Cameron, D. A., Earl, H. M., Pinder, S. E., Poole, C. J., Rea, D. W. et al.
(2018)
OPTIMA : A prospective randomized trial to validate the predictive utility and cost-effectiveness of gene expression test-directed chemotherapy decisions in early breast cancer.
Cancer Research, 78
(4).
Abstract OT1-06-01.
ISSN 0008-5472
doi:10.1158/1538-7445.SABCS17-OT1-06-01
Dunn, Janet A., Marshall, A. (Andrea)β, Campbell, Amy, Cameron, D., Earl, H., Macpherson, I., Poole, C., Rea, D., Francis, A., Harmer, V., Morgan, A., Stallard, Nigel, Makris, A., Hughes-Davies, L. and Stein, R. (2015) Practicalities of using an adaptive design for decision making within the optima trial : optimal personalized treatment of early breast cancer using multi-parameter tests. Trials, 16 (Supplement 2). P212. ISSN 1745-6215 doi:10.1186/1745-6215-16-S2-P212
Stein, R. C., Makris, A., Hughes-Davies, L., Bartlett, J. M. S., Marshall, A. (Andrea)β, Hall, P. S., Campbell, A., Pinder, S. E., Cameron, D. A., Rea, D. et al.
(2015)
Results of the OPTIMA (Optimal Personalized Treatment of early breast cancer usIng Multi-parameter Analysis) prelim study.
European Journal of Cancer Care, 51
(Supplement 3).
S268.
ISSN 0961-5423
doi:10.1016/S0959-8049(16)30762-6
Bartlett, J. M. S., Stein, R. C., Bayani, J., Marshall, A. (Andrea)β, Dunn, Janet A., Campbell, A. F., Cunningham, C., Sobol, M., Hall, P., Rooshenas, L., Morgan, A., Poole, Christopher J., Pinder, S. E., Cameron, D. A., Stallard, Nigel, Donovan, J., McCabe, C., Hughes-Davies, L. and Makris, A. (2015) Comparison of multiparameter tests in the UK OPTIMA-Prelim trial. Cancer Research, 75 (Supplement 9). P4-11-07 . ISSN 0008-5472 doi:10.1158/1538-7445.SABCS14-P4-11-07
Hall, P. S., Smith, A. F., Vargas-Palacios, A., Stein, R. C., Bartlett, J., Bayani, J., Marshall, A. (Andrea)β, Dunn, J. A., Campbell, A. F., Cunningham, C. et al.
(2015)
UK OPTIMA-prelim study demonstrates economic value in more clinical evaluation of multi-parameter prognostic tests in early breast cancer.
Cancer Research, 75
(9).
p. 2.
ISSN 0008-5472
doi:10.1158/1538-7445.SABCS14-P6-08-11
Stein, R., Makris, A., Hughes-Davies, L., Dunn, Janet A., Bartlett, J. M. S., Donovan, J., McCabe, C., Cameron, D. A., Canney, P., Earl, H. M., Francis, A., Morgan, A., Pinder, S., Rea, D., Poole, C. J., Hall, P., Hiller, L., Stallard, Nigel and Higgins, H. B. (2012) OPTIMA prelim : optimal personalized treatment of early breast cancer using multiparameter analysis : preliminary study. Journal of Clinical Oncology, 30 (15). ISSN 0732-183X
Parsons, Nicholas R., Friede, Tim, Todd, Susan and Stallard, Nigel (2011) Software tools for implementing simulation studies in adaptive seamless designs : introducing R package ASD. Trials, Vol.12 (Suppl.1). A8. ISSN 1745-6215 doi:10.1186/1745-6215-12-S1-A8
Report
Friede, Tim, Parsons, Nicholas R., Stallard, Nigel, Todd, S., Valdes Marquez, E., Chataway, J. and Nicholas, R. (2009) Adaptive clinical trial design for treatment selection and evaluation in multiple sclerosis (MS-Adaptive). UNSPECIFIED.
This list was generated on Fri Apr 19 18:42:03 2024 BST.