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Number of items: 80.
2023
Bayless, Adam M., Chen, Sisi, Ogden, Sam C., Xu, Xiaoyan, Sidda, John D., Manik, Mohammad K., Li, Sulin, Kobe, Bostjan, Ve, Thomas, Song, Lijiang, Grant, Murray R., Wan, Li and Nishimura, Marc T. (2023) Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products. Science Advances, 9 (11). eade8487. doi:10.1126/sciadv.ade8487 ISSN 2375-2548.
Jacob, Pierre, Hige, Junko, Song, Lijiang, Bayless, Adam, Russ, Dor, Bonardi, Vera, ElΒ Kasmi, Farid, WΓΌnsch, Lisa, Yang, Yu, Fitzpatrick, ConnorΒ R., McKinney, BrockΒ J., Nishimura, MarcΒ T., Grant, Murray R. and Dangl, JefferyΒ L. (2023) Broader functions of TIR domains in Arabidopsis immunity. Proceedings of the National Academy of Sciences, 120 (11). e2220921120. doi:10.1073/pnas.2220921120 ISSN 1091-6490.
Huang, Chuan, Zabala, Daniel, deΒ losΒ Santos, Emmanuel, Song, Lijiang, Corre, Christophe, Alkhalaf, Lona M. and Challis, Gregory L. (2023) Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis. Nucleic Acids Research, 51 (3). pp. 1488-1499. doi:10.1093/nar/gkad009 ISSN 1362-4962.
2022
Wang, Fang-Xin, Prokes, Ivan, Song, Lijiang, Shi, Huayun and Sadler, Peter J. (2022) Reactions of cisplatin and oxaliplatin with penicillin G : implications for drug inactivation and biological activity. JBIC Journal of Biological Inorganic Chemistry, 27 . pp. 695-704. doi:10.1007/s00775-022-01958-z ISSN 0949-8257.
Wang, Wenkai, Fan, Haojun, Song, Lijiang, Wang, Zhenya, Li, Heng, Xiang, Jun, Huang, Qiang and Chen, Xiangquan (2022) Organosilicon leather coating technology based on carbon peak strategy. Journal of Leather Science and Engineering, 4 (1). 27. doi:10.1186/s42825-022-00101-7 ISSN 2524-7859.
Manik, Mohammad K., Shi, Yun, Li, Sulin, Zaydman, Mark A., Damaraju, Neha, Eastman, Samuel, Smith, Thomas G., Gu, Weixi, Masic, Veronika, Mosaiab, Tamim et al.
(2022)
Cyclic ADP ribose isomers : production, chemical structures, and immune signaling.
Science, 377
(6614).
1510.
doi:10.1126/science.adc8969
ISSN 0036-8075.
Ashraf, Neelma, Zafar, Sana, Makitrynskyy, Roman, Bechthold, Andreas, Spiteller, Dieter, Song, Lijiang, Anwar, Munir Ahmad, Luzhetskyy, Andriy, Khan, Ali Nisar, Akhtar, Kalsoom and Khaliq, Shazia (2022) Revealing genome-based biosynthetic potential of Streptomyces sp. BR123 isolated from sunflower rhizosphere with broad spectrum antimicrobial activity. Antibiotics, 11 (8). 1057. doi:10.3390/antibiotics11081057 ISSN 2079-6382.
Chen, Feng, Romero-CanelΓ³n, Isolda, Habtemariam, Abraha, Song, Ji-Inn, Banerjee, Samya, Clarkson, Guy J., Song, Lijiang, Prokes, Ivan and Sadler, Peter J. (2022) Effect of cysteine thiols on the catalytic and anticancer activity of Ru(ii) sulfonyl-ethylenediamine complexes. Dalton Transactions, 51 (11). pp. 4447-4457. doi:10.1039/D1DT03856G ISSN 1477-9226.
2021
Lim, Jieyan, Chintalapudi, Venkaiah, Gudmundsson, Haraldur G, Tran, Minh, Bernasconi, Alice, Blanco, Araceli, Song, Lijiang, Challis, Gregory L. and Anderson, Edward A (2021) Synthesis of the C1-C27 fragment of stambomycin D validates modular polyketide synthase-based stereochemical assignments. Organic Letters, 23 (19). pp. 7439-7444. doi:10.1021/acs.orglett.1c02650 ISSN 1523-7060.
Borsetto, Chiara, Raguideau, SΓ©bastien, Travis, Emma Rachel, Kim, Dae-Wi, Lee, Do-Hoon, Bottrill, Andrew R., Stark, Richard Jan, Song, Lijiang, Cha, Chang-Jun, Pearson, Jonathan M., Quince, Christopher, Singer, Andrew C. and Wellington, Elizabeth M. H. (2021) Impact of sulfamethoxazole on a riverine microbiome. Water Research, 201 . 117382. doi:10.1016/j.watres.2021.117382 ISSN 0043-1354.
Zhou, Shanshan, Bhukya, Hussain, Malet, Nicolas, Harrison, Peter J. , Rea, Dean, Belousoff, Matthew J., Venugopal, Hariprasad, Sydor, Paulina K., Styles, Kathryn, Song, Lijiang, Cryle, Max J., Alkhalaf, Lona M., FΓΌlΓΆp, Vilmos, Challis, Gregory L. and Corre, Christophe (2021) Molecular basis for control of antibiotic production by a bacterial hormone. Nature, 590 (7846). pp. 463-467. doi:10.1038/s41586-021-03195-x ISSN 0028-0836.
Chhun, Audam, Sousoni, Despoina, Aguilo-Ferretjans, Maria del Mar, Song, Lijiang, Corre, Christophe and Christie-Oleza, Joseph A. (2021) Phytoplankton trigger the production of cryptic metabolites in the marine actinobacterium Salinispora tropica. Microbial Biotechnology, 14 (1). pp. 291-306. doi:10.1111/1751-7915.13722 ISSN 1751-7907.
2020
Zhou, Shanshan, Malet, Nicolas, Song, Lijiang, Corre, Christophe and Challis, Gregory L. (2020) MmfL catalyses formation of a phosphorylated butenolide intermediate in methylenomycin furan biosynthesis. Chemical Communications, 56 (92). pp. 14443-14446. doi:10.1039/d0cc05658h ISSN 1364-548X.
Sidda, John D., Song, Lijiang, Parker, Jack L., Studholme, David J., Sambles, Christine and Grant, Murray (2020) Diversity of secoiridoid glycosides in leaves of UK and Danish ash provide new insight for ash dieback management. Scientific Reports, 10 (1). 19566 . doi:10.1038/s41598-020-76140-z ISSN 2045-2322.
Becher, Paul G., Verschut, Vasiliki, Bibb, Maureen J., Bush, Matthew J., MolnΓ‘r, BΓ©la P., Barane, Elisabeth, Al-Bassam, Mahmoud M., Chandra, Govind, Song, Lijiang, Challis, Gregory L., Buttner, Mark J. and FlΓ€rdh, Klas (2020) Developmentally regulated volatiles geosmin and 2-methylisoborneol attract a soil arthropod to Streptomyces bacteria promoting spore dispersal. Nature microbiology, 5 . pp. 821-829. doi:10.1038/s41564-020-0697-x ISSN 2058-5276.
Banks, Alice M., Song, Lijiang, Challis, Gregory L., Bailey, Andy M. and Foster, Gary D. (2020) Bovistol B, bovistol D and strossmayerin : Sesquiterpene metabolites from the culture filtrate of the basidiomycete Coprinopsis strossmayeri. PLoS One, 15 (4). e0229925. doi:10.1371/journal.pone.0229925 ISSN 1932-6203.
2019
Zhou, Shanshan, Song, Lijiang, Masschelein, Joleen, Sumang, Felaine A. M., Papa, Irene A., Zulaybar, Teofila O., Custodio, Aileen B., Zabala, Daniel, Alcantara, Edwin P., Emmanuel de los Santos, L. C. and Challis, Gregory L. (2019) Pentamycin biosynthesis in Philippine Streptomyces sp. S816 : cytochrome P450-catalyzed installation of the C-14 hydroxyl group. ACS Chemical Biology, 14 (6). pp. 1305-1309. doi:10.1021/acschembio.9b00270 ISSN 1554-8929.
Thankachan, Divya, Fazal, Asif, Francis, Daniel, Song, Lijiang, Webb, Michael E. and Seipke, Ryan F. (2019) A trans-Acting Cyclase Offloading Strategy for Nonribosomal Peptide Synthetases. ACS Chemical Biology, 14 (5). pp. 845-849. doi:10.1021/acschembio.9b00095 ISSN 1554-8929.
Alberti, Fabrizio, Leng, Daniel J., Wilkening, Ina, Song, Lijiang, Tosin, Manuela and Corre, Christophe (2019) Triggering the expression of a silent gene cluster from genetically intractable bacteria results in scleric acid discovery. Chemical Science, 10 (2). pp. 453-463. doi:10.1039/C8SC03814G ISSN 2041-6520.
2018
Perry, Christopher, Sargeant, Jacob R., Song, Lijiang and Challis, Gregory L. (2018) Relative stereochemical assignment of C-33 and C-35 in the antibiotic gladiolin. Tetrahedron, 74 (38). pp. 5150-5155. doi:10.1016/j.tet.2018.06.060 ISSN 0040-4020 .
Banerjee, Samya, Soldevila-Barreda, Joan J., Wolny, Juliusz A., Wootton, Christopher, Habtemariam, Abraha, Romero-CanelΓ³n, Isolda, Chen, Feng, Clarkson, Guy J., Prokes, Ivan, Song, Lijiang, O'Connor, Peter B., SchΓΌnemann, Volker and Sadler, P. J. (2018) New activation mechanism for half-sandwich organometallic anticancer complexes. Chemical Science, 9 (12). pp. 3177-3185. doi:10.1039/c7sc05058e ISSN 2041-6539.
2017
Sotenko, Maria V., Coles, Stuart R., Barker, Guy C., Song, Lijiang, Jiang, Ying, Longhurst, Philip, Romanova, Tamara, Shuvaeva, Olga and Kirwan, Kerry (2017) Phytoremediation-biorefinery tandem for effective clean-up of metal contaminated soil and biomass valorisation. International Journal of Phytoremediation, 19 (11). pp. 965-975. doi:10.1080/15226514.2016.1267705 ISSN 1522-6514.
Blessborn, Daniel, Kaewkhao, Karnrawee, Song, Lijiang, White, Nicholas J., Day, Nicholas P. J. and Tarning, Joel (2017) Quantification of the antimalarial drug pyronaridine in whole blood using LCβMS/MS β increased sensitivity resulting from reduced non-specific binding. Journal of Pharmaceutical and Biomedical Analysis, 146 . pp. 214-219. doi:10.1016/j.jpba.2017.08.023 ISSN 0731-7085.
Anderson, Zoe J., Hobson, Christian, Needley, Rebecca, Song, Lijiang, Perryman, Michael S., Kerby, Paul D. and Fox, David J. (2017) NMR-based assignment of isoleucine vs allo-isoleucine stereochemistry. Organic & Biomolecular Chemistry, 15 (44). 9372-9378 . doi:10.1039/C7OB01995E ISSN 1477-0520.
Song, Lijiang, Jenner, Matthew, Masschelein, Joleen, Jones, Cerith, Bull, Matthew J., Harris, Simon R., Hartkoorn, Ruben C., Vocat, Anthony, Romero-CanelΓ³n, Isolda, Coupland, Paul, Webster, Gordon, Dunn, Matthew, Weiser, Rebecca, Paisey, Christopher, Cole, Stewart T., Parkhill, Julian, Mahenthiralingam, Eshwar and Challis, Gregory L. (2017) Discovery and biosynthesis of Gladiolin : a Burkholderia gladioli antibiotic with promising activity against Mycobacterium tuberculosis. Journal of the American Chemical Society, 139 (23). pp. 7974-7981. doi:10.1021/jacs.7b03382 ISSN 0002-7863.
Tsypik, Olga, Makitrynskyy, Roman, Bera, Agnieszka, Song, Lijiang, Wohlleben, Wolfgang, Fedorenko, Victor and Ostash, Bohdan (2017) Role of GntR family regulatory gene SCO1678 in gluconate metabolism in streptomyces coelicolor M145. BioMed Research International, 2017 . pp. 1-9. 9529501. doi:10.1155/2017/9529501 ISSN 2314-6133.
Inahashi, Yuki, Zhou, Shanshan, Bibb, Maureen J., Song, Lijiang, Al-Bassam, Mahmoud M., Bibb, Mervyn J. and Challis, Gregory L. (2017) Watasemycin biosynthesis in Streptomyces venezuelae : thiazoline C-methylation by a type B radical-SAM methylase homologue. Chemical Science, 8 (4). pp. 2823-2831. doi:10.1039/c6sc03533g ISSN 2041-6520.
2016
Ray, Lauren, Valentic, Timothy R., Miyazawa, Takeshi, Withall, David M., Song, Lijiang, Milligan, Jacob C., Osada, Hiroyuki, Takahashi, Shunji, Tsai, Shiou-Chuan and Challis, Gregory L. (2016) A crotonyl-CoA reductase-carboxylase independent pathway for assembly of unusual alkylmalonyl-CoA polyketide synthase extender units. Nature Communications, 7 . 13609. doi:10.1038/ncomms13609 ISSN 2041-1723.
Thanapipatsiri, Anyarat, Gomez-Escribano, Juan Pablo, Song, Lijiang, Bibb, Maureen J., Al-Bassam, Mahmoud, Chandra, Govind, Thamchaipenet, Arinthip, Challis, Gregory L. and Bibb, Mervyn J. (2016) Discovery of unusual biaryl polyketides by activation of a silent streptomyces venezuelae biosynthetic gene cluster. Chembiochem, 17 (22). pp. 2189-2198. doi:10.1002/cbic.201600396 ISSN 1439-4227.
Wilkening, Ina, Gazzola, Silvia, Riva, Elena, Parascandolo, James S., Song, Lijiang and Tosin, Manuela (2016) Second-generation probes for biosynthetic intermediate capture : towards a comprehensive profiling of polyketide assembly. Chemical Communications, 52 (68). 10392-10395 . doi:10.1039/C6CC04681A ISSN 1359-7345.
Sidda, John D., Poon, Vincent, Song, Lijiang, Wang, Weishan, Yang, Keqian and Corre, Christophe (2016) Overproduction and identification of butyrolactones SCB1-8 in the antibiotic production superhost Streptomyces M1152. Organic and Biomolecular Chemistry, 14 . pp. 6390-6393. doi:10.1039/c6ob00840b ISSN 1477-0520.
Uytterhoeven, Birgit, Appermans, Kenny, Song, Lijiang, Masschelein, Joleen, Lathouwers, Thomas , Michiels, Chris W. and Lavigne, Rob (2016) Systematic analysis of the kalimantacin assembly line NRPS module using an adapted targeted mutagenesis approach. Microbiology Open, 5 (2). pp. 279-286. doi:10.1002/mbo3.326 ISSN 2045-8827.
Zabala, Daniel, Cartwright, Joshua W., Roberts, Douglas M., Law, Brian J. C., Song, Lijiang, Samborskyy, Markiyan, Leadlay, P. F., Micklefield, Jason and Challis, Gregory L. (2016) A flavin-dependent decarboxylaseβdehydrogenaseβmonooxygenase assembles the warhead of Ξ±,Ξ²-Epoxyketone proteasome inhibitors. Journal of the American Chemical Society, 138 (13). pp. 4342-4345. doi:10.1021/jacs.6b01619 ISSN 0002-7863.
Parascandolo, James S., Havemann, Judith, Potter, Helen K., Huang, Fanglu, Riva, Elena, Connolly, Jack, Wilkening, Ina, Song, Lijiang, Leadlay, P. F. and Tosin, Manuela (2016) Insights into 6-methylsalicylic acid bio-assembly by using chemical probes. Angewandte Chemie International Edition, 55 (10). pp. 3463-3467. doi:10.1002/anie.201509038 ISSN 1433-7851.
Amaratunga, Chanaki, Lim, Pharath, Suon, Seila, Sreng, Sokunthea, Mao, Sivanna, Sopha, Chantha, Sam, Baramey, Dek, Dalin, Try, Vorleak, Amato, Roberto, Blessborn, Daniel, Song, Lijiang, Tullo, Gregory S., Fay, Michael P., Anderson, Jennifer M., Tarning, Joel and Fairhurst, Rick M. (2016) Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia : a multisite prospective cohort study. The Lancet Infectious Diseases, 16 (3). pp. 357-365. doi:10.1016/S1473-3099(15)00487-9 ISSN 1473-3099.
Amaratunga, Chanaki, Lim, Pharath, Suon, Seila, Sreng, Sokunthea, Mao, Sivanna, Sopha, Chantha, Sam, Baramey, Dek, Dalin, Try, Vorleak, Amato, Roberto, Blessborn, Daniel, Song, Lijiang, Tullo, Gregory S., Fay, Michael P., Anderson, Jennifer M., Tarning, Joel and Fairhurst, Rick M. (2016) Dihydroartemisininβpiperaquine resistance in Plasmodium falciparum malaria in Cambodia : a multisite prospective cohort study. The Lancet Infectious Diseases, 16 (3). pp. 357-365. doi:10.1016/S1473-3099(15)00487-9 ISSN 1473-3099.
Rowe, R. A., Jones, C., Bull, M. J., Jenner, M., Song, L., Dashti, Y., Harris, S. R., Parkhill, J., Connor, T. R., Challis, G. L. and Mahenthiralingam, E. (2016) Characterisation of vietnamycin : a novel Burkholderia antibiotic targeting mupirocin-resistant methicillin-resistant Staphylococcus aureus (MRSA). Planta Medica, 81 (S 01). S1-S381. doi:10.1055/s-0036-1596684 ISSN 0032-0943.
Masschelein, Joleen, Sydor, P. K., Griffiths, D. E., Valentic, T. R., Gallo, A., Jones, C., Song, L., Tsai, S. C., Lewandowski, J. R., Mahenthiralingam, E. and Challis, G. L. (2016) Dissection and rational engineering of the biosynthetic pathway to enacyloxin, a promising anti-Gram-negative antibiotic. Planta Medica, 81 (S 01). S1-S381. doi:10.1055/s-0036-1596129 ISSN 0032-0943.
Jones, C., Bull, M. J., Jenner, M., Song, L., Dashti, Y., Harris, S. R., Parkhill, J., Connor, T. R., Challis, G. L. and Mahenthiralingam, E. (2016) Genome mining and characterisation of multiple bioactive compounds from a Burkholderia gladioli isolate collection. Planta Medica, 81 (S 01). S1-S381. doi:10.1055/s-0036-1596149 ISSN 0032-0943.
2015
Li, Ning, Song, Lijiang, Liu, Minghao, Shang, Fei, Anderson, Zoe, Fox, David J., Challis, Gregory L. and Huang, Yingping (2015) Unique post-translational oxime formation in the biosynthesis of the azolemycin complex of novel ribosomal peptides from Streptomyces sp. FXJ1.264. Chemical Science, 7 (1). pp. 482-488. doi:10.1039/c5sc03021h ISSN 2041-6520.
Leang, Rithea, Taylor, Walter R. J., Bouth, Denis Mey, Song, Lijiang, Tarning, Joel, Char, Meng Chuor, Kim, Saorin, Witkowski, Benoit, Duru, Valentine, Domergue, Anais, Khim, Nimol, Ringwald, Pascal and Menard, Didier (2015) Evidence of plasmodium falciparum Malaria multidrug resistance to artemisinin and piperaquine in Western Cambodia : dihydroartemisinin-piperaquine open-label multicenter clinical assessment. Antimicrobial Agents and Chemotherapy, 59 (8). pp. 4719-4726. doi:10.1128/AAC.00835-15 ISSN 0066-4804.
2014
Sidda, John D., Song, Lijiang, Poon, Vincent, Al-Bassam, Mahmoud, Lazos, Orestis, Buttner, Mark J., Challis, Gregory L. and Corre, Christophe (2014) Discovery of a family of Ξ³-aminobutyrate ureas via rational derepression of a silent bacterial gene cluster. Chemical Science, Volume 5 . pp. 86-89. doi:10.1039/c3sc52536h ISSN 2041-6520.
Gubbens, Jacob, Zhu, Hua, Girard, Geneviève, Song, Lijiang, Florea, Bogdan I., Aston, Philip R. , Ichinose, Koji, Filippov, Dmitri V., Choi, Young H., Overkleeft, Herman S., Challis, Gregory L. and van Wezel, Gilles P. (2014) Natural product proteomining, a quantitative proteomics platform, allows rapid discovery of biosynthetic gene clusters for different classes of natural products. Chemistry & Biology, Volume 21 (Number 6). pp. 707-718. doi:10.1016/j.chembiol.2014.03.011 ISSN 1074-5521.
Suberu, John O., Yamin, Peyman, Leonhard, Kai, Song, Lijiang, Chemat, Smain, Sullivan, Neil F., Barker, Guy C. and Lapkin, Alexei (2014) The effect of O-methylated flavonoids and other co-metabolites on the crystallization and purification of artemisinin. Journal of Biotechnology, Volume 171 . pp. 25-33. doi:10.1016/j.jbiotec.2013.11.024 ISSN 0168-1656.
Song, Lijiang, Laureti, Luisa, Corre, Christophe, Leblond, Pierre, Aigle, Bertrand and Challis, Gregory L. (2014) Cytochrome P450-mediated hydroxylation is required for polyketide macrolactonization in stambomycin biosynthesis. The Journal of Antibiotics, Volume 67 (Number 1). pp. 71-76. doi:10.1038/ja.2013.119 ISSN 0021-8820.
2013
Sidda, John D., Song, Lijiang, Poon, Vincent, Al Bassam, Mahmoud, Lazos, Orestis, Buttner, Mark J., Challis, Gregory L. and Corre, Christophe (2013) Discovery of a family of Ξ³-aminobutyrate ureas via rational derepression of a silent bacterial gene cluster. Chemical Sciences, 5 (1). pp. 86-89. doi:10.1039/C3SC52536H ISSN 2041-6539.
Suberu, John O., Song, Lijiang, Slade, Susan E., Sullivan, Neil F., Barker, Guy C. and Lapkin, Alexei (2013) A rapid method for the determination of artemisinin and its biosynthetic precursors in Artemisia annua L. crude extracts. Journal of Pharmaceutical and Biomedical Analysis, Volume 84 . pp. 269-277. doi:10.1016/j.jpba.2013.06.025 ISSN 0731-7085.
Zhao, Yao, (Researcher in chemistry), Woods, Julie A., Farrer, Nicola J., Robinson, Kim S., Pracharova, Jitka, Kasparkova, Jana, Novakova, Olga, Li, Huilin, Salassa, Luca, Pizarro, Ana M., Clarkson, Guy J., Song, Lijiang, Brabec, V. (Viktor) and Sadler, P. J. (2013) Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts. Chemistry - A European Journal, Volume 19 (Number 29). pp. 9578-9591. doi:10.1002/chem.201300374 ISSN 0947-6539.
Kodani, Shinya, Bicz, Joanna, Song, Lijiang, Deeth, Robert J., Ohnishi-Kameyama, Mayumi, Yoshida, Mitsuru, Ochi, Kozo and Challis, Gregory L. (2013) Structure and biosynthesis of scabichelin, a novel tris-hydroxamate siderophore produced by the plant pathogen Streptomyces scabies 87.22. Organic & Biomolecular Chemistry, Volume 11 (Number 28). pp. 4686-4694. doi:10.1039/c3ob40536b ISSN 1477-0520.
2012
Barry, Sarah M., Kers, Johan A, Johnson, Evan G, Song, Lijiang, Aston, Philip R. , Patel, Bhumit, Krasnoff, Stuart B, Crane, Brian R, Gibson, Donna M, Loria, Rosemary and Challis, Gregory L. (2012) Cytochrome P450βcatalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis. Nature Chemical Biology, Vol. 8 (No.10). pp. 814-816. doi:10.1038/nchembio.1048 ISSN 1552-4450.
Gerc, Amy J., Song, Lijiang, Challis, Gregory L., Stanley-Wall, Nicola R. and Coulthurst, Sarah J. (2012) The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin. PLoS One, Vol.7 (No.9). e44673. doi:10.1371/journal.pone.0044673 ISSN 1932-6203.
Lautru, Sylvie, Song, Lijiang, Demange, Luc, Lombès, Thomas, Galons, Hervé, Challis, Gregory L. and Pernodet, Jean-Luc (2012) A sweet origin for the key congocidine precursor 4-acetamidopyrrole-2-carboxylate. Angewandte Chemie International Edition, Volume 51 (Number 30). pp. 7454-7458. doi:10.1002/anie.201201445 ISSN 1433-7851.
Song, Lijiang, Laureti, L., Gomez-Escribano, J. P., Fox, David J., Yeo, V., Corre, Christophe, Huang, S., Leblond, P., Aigle, B., Bibb, M. and Challis, Gregory L. (2012) Bacterial genome mining for novel natural product discovery. Planta Medica, Volume 78 (Number 11). Article number IL7. doi:10.1055/s-0032-1320194 ISSN 0032-0943.
Milnes, Phillip J., McKee, Mireya L., Bath, Jonathan, Song, Lijiang, Stulz, Eugen, Turberfield, Andrew J. and O'Reilly, Rachel K. (2012) Sequence-specific synthesis of macromolecules using DNA-templated chemistry. Chemical Communications, Vol.48 (No.45). pp. 5614-5616. doi:10.1039/c2cc31975f ISSN 1359-7345.
Gomez-Escribano, Juan Pablo, Song, Lijiang, Fox, David J., Yeo, Valerie, Bibb, Mervyn J. and Challis, Gregory L. (2012) Structure and biosynthesis of the unusual polyketide alkaloid coelimycin P1, a metabolic product of the cpk gene cluster of Streptomyces coelicolor M145. Chemical Science, Volume 3 (Number 9). pp. 2716-2720. doi:10.1039/c2sc20410j ISSN 2041-6520.
Fu, Y. (Ying), Romero, Maria, Habtemariam, Abraha, Snowden, Michael E., Song, Lijiang, Clarkson, Guy J., Qamar, Bushra, Pizarro, Ana M., Unwin, Patrick R. and Sadler, P. J. (2012) The contrasting chemical reactivity of potent isoelectronic iminopyridine and azopyridine osmium(ii) arene anticancer complexes. Chemical Science, Vol.3 (No.8). pp. 2485-2494. doi:10.1039/c2sc20220d ISSN 2041-6520.
2011
Schmelz, Stefan, Botting, Catherine H., Song, Lijiang, Kadi, Nadia, Challis, Gregory L. and Naismith, James H. (2011) Structural basis for acyl acceptor specificity in the achromobactin biosynthetic enzyme AcsD. Journal of Molecular Biology, Vol.412 (No.3). pp. 495-504. doi:10.1016/j.jmb.2011.07.059 ISSN 0022-2836.
Seipke, R. F., Song, Lijiang, Bicz, Joanna, Laskaris, Paris, Yaxley, Alice M., Challis, Gregory L. and Loria, Rosemary (2011) The plant pathogen Streptomyces scabies 87-22 has a functional pyochelin biosynthetic pathway that is regulated by TetR- and AfsR-family proteins. Microbiology, Vol.157 (No.9). pp. 2681-2693. doi:10.1099/mic.0.047977-0 ISSN 1350-0872.
Mahenthiralingam, Eshwar, Song, Lijiang, Sass, Andrea, White, J. (Judith), Wilmot, Ceri, Marchbank, Angela, Boaisha, Othman, Paine, James, Knight, D. (David) and Challis, Gregory L. (2011) Enacyloxins are products of an unusual hybrid modular polyketide synthase encoded by a cryptic burkholderia ambifaria genomic island. Chemistry & Biology, Vol.18 (No.5). pp. 665-677. doi:10.1016/j.chembiol.2011.01.020 ISSN 1074-5521.
Sydor, Paulina K., Barry, Sarah M., Odulate, Olanipekun M., Barona-Gomez, Francisco, Haynes, Stuart W., Corre, Christophe, Song, Lijiang and Challis, Gregory L. (2011) Regio- and stereodivergent antibiotic oxidative carbocyclizations catalysed by Rieske oxygenase-like enzymes. Nature Chemistry, Vol.3 (No.5). pp. 388-392. doi:10.1038/nchem.1024 ISSN 1755-4330.
Laureti, L., Song, Lijiang, Huang, S., Corre, Christophe, Leblond, Pierre, Challis, Gregory L. and Aigle, B. (2011) Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens. Proceedings of the National Academy of Sciences of the United States of America, Vol.108 (No.15). pp. 6258-6263. doi:10.1073/pnas.1019077108 ISSN 0027-8424.
Bunet, R., Song, Lijiang, Mendes, M. V., Corre, Christophe, Hotel, L., Rouhier, N., Framboisier, X., Leblond, Pierre, Challis, Gregory L. and Aigle, B. (2011) Characterization and manipulation of the pathway-specific late regulator AlpW reveals streptomyces ambofaciens as a new producer of kinamycins. Journal of Bacteriology, Vol.193 (No.5). pp. 1142-1153. doi:10.1128/JB.01269-10 ISSN 0021-9193.
Malet, Nicolas, Song, Lijiang, Corre, Christophe and Challis, Gregory L. (2011) Structure-activity relationship and biosynthesis of signaling molecules controlling methylenomycin antibiotic production in Streptomyces coelicolor. American Chemical Society. Abstracts of Papers (at the National Meeting), Vol.241 (No.142-BIOL ). ISSN 0065-7727
Haynes, Stuart W., Sydor, Paulina K., Corre, Christophe, Song, Lijiang and Challis, Gregory L. (2011) Stereochemical elucidation of streptorubin B. Journal of the American Chemical Society, Vol.133 (No.6). pp. 1793-1798. doi:10.1021/ja109164t ISSN 0002-7863.
Aigle, B., Bunet, R., Corre, Christophe, Garenaux, AmΓ©lie, Hotel, L., Huang, S., Laureti, L., Lautru, Sylvie, Mendes, V. M., NezbedovΓ‘, S., Nguyen, H., Song, Lijiang, Challis, Gregory L., Leblond, Pierre and Pernodet, Jean-Luc (2011) Genome-guided exploration of streptomyces ambofaciens secondary metabolism. In: Streptomyces : molecular biology and biotechnology. [Wymondham]: Caister Academic, pp. 179-194. ISBN 9781904455776
Corre, Christophe, Haynes, Stuart W., Malet, Nicolas, Song, Lijiang and Challis, Gregory L. (2011) A butenolide intermediate in methylenomycin furan biosynthesis is implied by incorporation of stereospecifically C-13-labelled glycerols. Chemical Communications, Vol.46 (No.23). pp. 4079-4081. doi:10.1039/c000496k ISSN 1359-7345.
2010
Patel, Prakash, Song, Lijiang and Challis, Gregory L. (2010) Distinct extracytoplasmic siderophore binding proteins recognize ferrioxamines and ferricoelichelin in streptomyces coelicolor A3(2). Biochemistry, Vol.49 (No.37). pp. 8033-8042. doi:10.1021/bi100451k ISSN 0006-2960.
Mahenthiralingam, Eshwar, Song, Lijiang, White, J. (Judith), Wilmot, Ceri, Sass, Andrea, Marchbank, Angela and Challis, Gregory L. (2010) Burkholderia ambifaria produces a polyketide antibiotic that inhibits Burkholderia multivorans and other Burkholderia cepacia complex species. Pediatric Pulmonology, Vol.45 (No.S33). p. 345. ISSN 8755-6863.
Chen, Yin, Scanlan, Julie, Song, Lijiang, Crombie, Andrew, Rahman, M. Tanvir, SchΓ€fer, Hendrik and Murrell, J. C. (J. Colin) (2010) Gamma-Glutamylmethylamide Is an Essential Intermediate in the Metabolism of Methylamine by Methylocella silvestris. Applied and Environmental Microbiology, Vol.76 (No.13). pp. 4530-4537. doi:10.1128/AEM.00739-10 ISSN 0099-2240.
2009
Oves-Costales, Daniel, Song, Lijiang and Challis, Gregory L. (2009) Enantioselective desymmetrisation of citric acid catalysed by the substrate-tolerant petrobactin biosynthetic enzyme AsbA. Chemical Communications (No.11). pp. 1389-1391. doi:10.1039/b823147h ISSN 1359-7345.
Schmelz, Stefan, Kadi, Nadia, McMahon, Stephen A., Song, Lijiang, Oves-Costales, Daniel, Oke, Muse, Liu, Huanting, Johnson, K. A. (Kenneth A.), Carter, Lester G., Botting, Catherine H., White, Malcolm F., Challis, Gregory L. and Naismith, James H. (2009) AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. Nature Chemical Biology, Vol.5 (No.3). pp. 174-182. doi:10.1038/nchembio.145 ISSN 1552-4450.
2008
Heather, Zoe, Holden, Matthew T. G., Steward, Karen F., Parkhill, Julian, Song, Lijiang, Challis, Gregory L., Robinson, C. (Carl), Davis-Poynter, Nicholas and Waller, Andrew S. (2008) A novel streptococcal integrative conjugative element involved in iron acquisition. Molecular Microbiology, Volume 70 (Number 5). pp. 1274-1292. doi:10.1111/j.1365-2958.2008.06481.x ISSN 0950-382X.
Corre, Christophe, Song, Lijiang, O'Rourke, S. (Sean), Chater, K. F. and Challis, Gregory L. (2008) 2-Alkyl-4-hydroxymethylfuran-3-carboxylic acids, antibiotic production inducers discovered by Streptomyces coelicolor genome mining. Proceedings of the National Academy of Sciences of the United States of America, Vol.105 (No.45). pp. 17510-17515. doi:10.1073/pnas.0805530105 ISSN 0027-8424.
Kadi, Nadia, Song, Lijiang and Challis, Gregory L. (2008) Bisucaberin biosynthesis : an adenylating domain of the BibC multi-enzyme catalyzes cyclodimerization of N-hydroxy-N-succinylcadaverine. Chemical Communications (No.41). pp. 5119-5121. doi:10.1039/b813029a ISSN 1359-7345.
Oves-Costales, Daniel, Kadi, Nadia, Fogg, Mark J., Song, Lijiang, Wilson, Keith S. and Challis, Gregory L. (2008) Petrobactin biosynthesis: AsbB catalyzes condensation of spermidine with N-8-citryl-spermidine and its N-1-(3,4-dihydroxybenzoyl) derivative. Chemical Communications (No.34). pp. 4034-4036. doi:10.1039/b809353a ISSN 1359-7345.
Kadi, Nadia, Arbache, Simon, Song, Lijiang, Oves-Costales, Daniel and Challis, Gregory L. (2008) Identification of a gene cluster that directs putrebactin biosynthesis in Shewanella species : PubC catalyzes cyclodimerization of N-hydroxy-N-succinyiputrescine. Journal of the American Chemical Society, Vol.130 (No.32). pp. 10458-10459. doi:10.1021/ja8027263 ISSN 0002-7863.
Haynes, Stuart W., Sydor, Paulina K., Stanley, Anna E., Song, Lijiang and Challis, Gregory L. (2008) Role and substrate specificity of the Streptomyces coelicolor RedH enzyme in undecylprodiginine biosynthesis. Chemical Communications (No.16). pp. 1865-1867. doi:10.1039/b801677a ISSN 1359-7345.
Mo, SangJoon, Sydor, Paulina K., Corre, Christophe, Alhamadsheh, Mamoun M., Stanley, Anna E., Haynes, Stuart W., Song, Lijiang, Reynolds, Kevin A. and Challis, Gregory L. (2008) Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis. Chemistry & Biology, Vol.15 (No.2). pp. 137-148. doi:10.1016/j.chembiol.2007.11.015 ISSN 1074-5521.
2007
Oves-Costales, Daniel, Kadi, Nadia, Fogg, Mark J., Song, Lijiang, Wilson, Keith S. and Challis, Gregory L. (2007) Enzymatic logic of anthrax stealth siderophore biosynthesis: AsbA catalyzes ATP-Dependent condensation of citric acid and spermidine. Journal of the American Chemical Society, Vol.129 (No.27). pp. 8416-8417. doi:10.1021/ja072391o ISSN 0002-7863.
2006
Song, Lijiang, Barona-Gomez, Francisco, Corre, Christophe, Xiang, Longkuan, Udwary, Daniel W., Austin, Michael B., Noel, Joseph P., Moore, Bradley S. and Challis, Gregory L. (2006) Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining. Journal of the American Chemical Society, 128 (46). pp. 14754-14755. doi:10.1021/ja065247w ISSN 0002-7863.
This list was generated on Fri Apr 19 20:59:55 2024 BST.