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Jump to: Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC) | Birmingham Science City | Croatia. Ministarstvo znanosti, obrazovanja i športa | European Union FP6 Integrated Project EUR-INTAFAR | Fonds FCAR (Québec) | Fonds de la recherche en santé du Québec (FRSQ) | Javna Agencija za Raziskovalno Dejavnost Republike Slovenije [Public Research Agency of the Republic of Slovenia] (ARRS) | Javni Sklad Republike Slovenije za Razvoj Kadrov in Štipendije [Slovene Human Resources and Scholarship Fund] | Lister Institute of Preventive Medicine | Medical Research Council (Great Britain) (MRC) | Medical Research Council (MRC) | Ministry of Higher Education, Science and Technology of the Republic of Slovenia | National Health and Medical Research Council (Australia) (NHMRC) | Natural Sciences and Engineering Research Council of Canada | Networks of Centres of Excellence (Canada) | Quebecois de la Recherche sur la Nature et les Technologies | Royal Society | Royal Society (Great Britain) | Royal Society (Great Britain). Wolfson Research Merit Award (RSWRMA) | Science City Research Alliance | Seventh Framework Programme (European Commission) (FP7) | Sixth Framework Programme (European Commission) (FP6) | Slovenia. Ministrstvo za izobraževanje, znanost in šport (MIZŠ) | University of Warwick | Wellcome Trust (London, England)
Number of items: 48.
Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC)
Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Košmrlj, Janez and Dowson, Christopher G. (2017) Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi:10.1016/j.ejmech.2016.12.060 ISSN 0223-5234.
Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Thanh, Giang Le, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X. et al.
(2015)
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Nature Communications, 6
.
pp. 1-11.
7719.
doi:10.1038/ncomms8719
ISSN 2041-1723.
Ruane, Karen M., Lloyd, Adrian J., Fülöp, Vilmos, Dowson, Christopher G., Barreteau, Hélène, Boniface, Audrey, Dementin, Sébastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andréa and Roper, David I. (2013) Specificity determinants for lysine incorporation in staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex. Journal of Biological Chemistry, Volume 288 (Number 46). Article number 33439. doi:10.1074/jbc.M113.508135 ISSN 0021-9258.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
Birmingham Science City
Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A. and Besra, Gurdyal S. (2016) Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase. Scientific Reports, 6 . 23191. doi:10.1038/srep23191 ISSN 2045-2322.
Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Thanh, Giang Le, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X. et al.
(2015)
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Nature Communications, 6
.
pp. 1-11.
7719.
doi:10.1038/ncomms8719
ISSN 2041-1723.
Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I. and Dowson, Christopher G. (2013) Adenosine Tetraphosphoadenosine drives a continuous ATP-release assay for Aminoacyl-tRNA synthetases and other Adenylate-forming enzymes. ACS Chemical Biology, 8 (10). pp. 2157-2163. doi:10.1021/cb400248f ISSN 1554-8929.
Croatia. Ministarstvo znanosti, obrazovanja i športa
Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Košmrlj, Janez and Dowson, Christopher G. (2017) Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi:10.1016/j.ejmech.2016.12.060 ISSN 0223-5234.
European Union FP6 Integrated Project EUR-INTAFAR
Sova, Matej, Cadez, Gasper, Turk, Samo, Majce, Vita, Polanc, Slovenko, Batson, Sarah, Lloyd, Adrian, Roper, David I., Fishwick, Colin W. G. and Gobec, Stanislav (2009) Design and synthesis of new hydroxyethylamines as inhibitors of D-alanyl-D-lactate ligase (VanA) and D-alanyl-D-alanine ligase (DdlB). Bioorganic & Medicinal Chemistry Letters, Vol.19 (No.5). pp. 1376-1379. doi:10.1016/j.bmcl.2009.01.034 ISSN 0960-894X.
Fonds FCAR (Québec)
Paradis-Bleau , Catherine, Lloyd, Adrian, Sanschagrin, François, Clark, Tom, Blewett, Ann, Bugg, Tim and Levesque, Roger C. (2008) Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. BMC Biochemistry, Vol.9 (No.33). doi:10.1186/1471-2091-9-33 ISSN 1471-2091.
Fonds de la recherche en santé du Québec (FRSQ)
Paradis-Bleau , Catherine, Lloyd, Adrian, Sanschagrin, François, Clark, Tom, Blewett, Ann, Bugg, Tim and Levesque, Roger C. (2008) Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. BMC Biochemistry, Vol.9 (No.33). doi:10.1186/1471-2091-9-33 ISSN 1471-2091.
Javna Agencija za Raziskovalno Dejavnost Republike Slovenije [Public Research Agency of the Republic of Slovenia] (ARRS)
Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Košmrlj, Janez and Dowson, Christopher G. (2017) Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi:10.1016/j.ejmech.2016.12.060 ISSN 0223-5234.
Javni Sklad Republike Slovenije za Razvoj Kadrov in Štipendije [Slovene Human Resources and Scholarship Fund]
Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Košmrlj, Janez and Dowson, Christopher G. (2017) Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi:10.1016/j.ejmech.2016.12.060 ISSN 0223-5234.
Lister Institute of Preventive Medicine
Alderwick, Luke J., Lloyd, Georgina S., Lloyd, Adrian, Lovering, Andrew L., Eggeling, L. and Besra, Gurdyal S. (2011) Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase. Glycobiology, Vol.21 (No.4). pp. 410-425. doi:10.1093/glycob/cwq173 ISSN 1460-2423.
Medical Research Council (Great Britain) (MRC)
Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Košmrlj, Janez and Dowson, Christopher G. (2017) Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi:10.1016/j.ejmech.2016.12.060 ISSN 0223-5234.
Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A. and Besra, Gurdyal S. (2016) Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase. Scientific Reports, 6 . 23191. doi:10.1038/srep23191 ISSN 2045-2322.
Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Thanh, Giang Le, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X. et al.
(2015)
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Nature Communications, 6
.
pp. 1-11.
7719.
doi:10.1038/ncomms8719
ISSN 2041-1723.
Gurcha, Sudagar S., Usha, Veeraraghavan, Cox, Jonathan A. G., Fütterer, Klaus, Abrahams, Katherine A., Bhatt, Apoorva, Alderwick, Luke J., Reynolds, Robert C., Loman, Nicholas J., Nataraj, VijayaShankar, Alemparte, Carlos, Barros, David, Lloyd, Adrian J., Ballell, Lluis, Hobrath, Judith V. and Besra, Gurdyal S. (2014) Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target. PLoS One, Volume 9 (Number 11). Article number e113568. doi:10.1371/journal.pone.0113568 ISSN 1932-6203.
Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I. and Dowson, Christopher G. (2013) Adenosine Tetraphosphoadenosine drives a continuous ATP-release assay for Aminoacyl-tRNA synthetases and other Adenylate-forming enzymes. ACS Chemical Biology, 8 (10). pp. 2157-2163. doi:10.1021/cb400248f ISSN 1554-8929.
Lloyd, Adrian J., Potter, Nicola J., Fishwick, Colin W. G., Roper, David I. and Dowson, Christopher G. (2013) Adenosine tetraphosphoadenosine drives a continuous ATP-release assay for aminoacyl-tRNA synthetases and other adenylate-forming enzymes. ACS Chemical Biology, 8 (10). pp. 2157-2163. doi:10.1021/cb400248f ISSN 1554-8929.
Ruane, Karen M., Lloyd, Adrian J., Fülöp, Vilmos, Dowson, Christopher G., Barreteau, Hélène, Boniface, Audrey, Dementin, Sébastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andréa and Roper, David I. (2013) Specificity determinants for lysine incorporation in staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex. Journal of Biological Chemistry, Volume 288 (Number 46). Article number 33439. doi:10.1074/jbc.M113.508135 ISSN 0021-9258.
Alderwick, Luke J., Lloyd, Georgina S., Lloyd, Adrian, Lovering, Andrew L., Eggeling, L. and Besra, Gurdyal S. (2011) Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase. Glycobiology, Vol.21 (No.4). pp. 410-425. doi:10.1093/glycob/cwq173 ISSN 1460-2423.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
Medical Research Council (MRC)
Usha, Veeraraghavan, Gurcha, Sudagar S., Lovering, Andrew L., Lloyd, Adrian, Papaemmanouil, A., Reynolds, Robert C. and Besra, Gurdyal S. (2011) Identification of novel diphenyl urea inhibitors of Mt-GuaB2 active against Mycobacterium tuberculosis. Microbiology, Vol.157 (No.1). pp. 290-299. doi:10.1099/mic.0.042549-0 ISSN 1350-0872.
Ministry of Higher Education, Science and Technology of the Republic of Slovenia
Sova, Matej, Cadez, Gasper, Turk, Samo, Majce, Vita, Polanc, Slovenko, Batson, Sarah, Lloyd, Adrian, Roper, David I., Fishwick, Colin W. G. and Gobec, Stanislav (2009) Design and synthesis of new hydroxyethylamines as inhibitors of D-alanyl-D-lactate ligase (VanA) and D-alanyl-D-alanine ligase (DdlB). Bioorganic & Medicinal Chemistry Letters, Vol.19 (No.5). pp. 1376-1379. doi:10.1016/j.bmcl.2009.01.034 ISSN 0960-894X.
National Health and Medical Research Council (Australia) (NHMRC)
Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Thanh, Giang Le, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X. et al.
(2015)
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Nature Communications, 6
.
pp. 1-11.
7719.
doi:10.1038/ncomms8719
ISSN 2041-1723.
Natural Sciences and Engineering Research Council of Canada
Paradis-Bleau, Catherine, Lloyd, Adrian, Sanschagrin, Francois, Maaroufi, Halim, Clarke, Thomas B., Blewett, Ann, Dowson, Christopher G., Roper, David I., Bugg, Tim and Levesque, Roger C. (2009) Pseudomonas aeruginosa MurE amide ligase : enzyme kinetics and peptide inhibitor. Biochemical Journal, Vol.421 (No. 2). pp. 263-272. doi:10.1042/BJ20081395 ISSN 0264-6021.
Networks of Centres of Excellence (Canada)
Paradis-Bleau , Catherine, Lloyd, Adrian, Sanschagrin, François, Clark, Tom, Blewett, Ann, Bugg, Tim and Levesque, Roger C. (2008) Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF. BMC Biochemistry, Vol.9 (No.33). doi:10.1186/1471-2091-9-33 ISSN 1471-2091.
Quebecois de la Recherche sur la Nature et les Technologies
Paradis-Bleau, Catherine, Lloyd, Adrian, Sanschagrin, Francois, Maaroufi, Halim, Clarke, Thomas B., Blewett, Ann, Dowson, Christopher G., Roper, David I., Bugg, Tim and Levesque, Roger C. (2009) Pseudomonas aeruginosa MurE amide ligase : enzyme kinetics and peptide inhibitor. Biochemical Journal, Vol.421 (No. 2). pp. 263-272. doi:10.1042/BJ20081395 ISSN 0264-6021.
Royal Society
Usha, Veeraraghavan, Gurcha, Sudagar S., Lovering, Andrew L., Lloyd, Adrian, Papaemmanouil, A., Reynolds, Robert C. and Besra, Gurdyal S. (2011) Identification of novel diphenyl urea inhibitors of Mt-GuaB2 active against Mycobacterium tuberculosis. Microbiology, Vol.157 (No.1). pp. 290-299. doi:10.1099/mic.0.042549-0 ISSN 1350-0872.
Royal Society (Great Britain)
Alderwick, Luke J., Lloyd, Georgina S., Lloyd, Adrian, Lovering, Andrew L., Eggeling, L. and Besra, Gurdyal S. (2011) Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase. Glycobiology, Vol.21 (No.4). pp. 410-425. doi:10.1093/glycob/cwq173 ISSN 1460-2423.
Royal Society (Great Britain). Wolfson Research Merit Award (RSWRMA)
Gurcha, Sudagar S., Usha, Veeraraghavan, Cox, Jonathan A. G., Fütterer, Klaus, Abrahams, Katherine A., Bhatt, Apoorva, Alderwick, Luke J., Reynolds, Robert C., Loman, Nicholas J., Nataraj, VijayaShankar, Alemparte, Carlos, Barros, David, Lloyd, Adrian J., Ballell, Lluis, Hobrath, Judith V. and Besra, Gurdyal S. (2014) Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target. PLoS One, Volume 9 (Number 11). Article number e113568. doi:10.1371/journal.pone.0113568 ISSN 1932-6203.
Science City Research Alliance
Ruane, Karen M., Lloyd, Adrian J., Fülöp, Vilmos, Dowson, Christopher G., Barreteau, Hélène, Boniface, Audrey, Dementin, Sébastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andréa and Roper, David I. (2013) Specificity determinants for lysine incorporation in staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex. Journal of Biological Chemistry, Volume 288 (Number 46). Article number 33439. doi:10.1074/jbc.M113.508135 ISSN 0021-9258.
Seventh Framework Programme (European Commission) (FP7)
Gurcha, Sudagar S., Usha, Veeraraghavan, Cox, Jonathan A. G., Fütterer, Klaus, Abrahams, Katherine A., Bhatt, Apoorva, Alderwick, Luke J., Reynolds, Robert C., Loman, Nicholas J., Nataraj, VijayaShankar, Alemparte, Carlos, Barros, David, Lloyd, Adrian J., Ballell, Lluis, Hobrath, Judith V. and Besra, Gurdyal S. (2014) Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target. PLoS One, Volume 9 (Number 11). Article number e113568. doi:10.1371/journal.pone.0113568 ISSN 1932-6203.
Sixth Framework Programme (European Commission) (FP6)
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
Slovenia. Ministrstvo za izobraževanje, znanost in šport (MIZŠ)
Vajs, Jure, Proud, Conor, Brozovic, Anamaria, Gazvoda, Martin, Lloyd, Adrian J., Roper, David I., Osmak, Maja, Košmrlj, Janez and Dowson, Christopher G. (2017) Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis. European Journal of Medicinal Chemistry, 127 . pp. 223-234. doi:10.1016/j.ejmech.2016.12.060 ISSN 0223-5234.
University of Warwick
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
Wellcome Trust (London, England)
Usha, Veeraraghavan, Lloyd, Adrian J., Roper, David I., Dowson, Christopher G., Kozlov, Guennadi, Gehring, Kalle, Chauhan, Smita, Imam, Hasan T., Blindauer, Claudia A. and Besra, Gurdyal S. (2016) Reconstruction of diaminopimelic acid biosynthesis allows characterisation of Mycobacterium tuberculosis N-succinyl-L,L-diaminopimelic acid desuccinylase. Scientific Reports, 6 . 23191. doi:10.1038/srep23191 ISSN 2045-2322.
Zuegg, Johannes, Muldoon, Craig, Adamson, George, McKeveney, Declan, Thanh, Giang Le, Premraj, Rajaratnam, Becker, Bernd, Cheng, Mu, Elliott, Alysha G., Huang, Johnny X. et al.
(2015)
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity.
Nature Communications, 6
.
pp. 1-11.
7719.
doi:10.1038/ncomms8719
ISSN 2041-1723.
Gurcha, Sudagar S., Usha, Veeraraghavan, Cox, Jonathan A. G., Fütterer, Klaus, Abrahams, Katherine A., Bhatt, Apoorva, Alderwick, Luke J., Reynolds, Robert C., Loman, Nicholas J., Nataraj, VijayaShankar, Alemparte, Carlos, Barros, David, Lloyd, Adrian J., Ballell, Lluis, Hobrath, Judith V. and Besra, Gurdyal S. (2014) Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target. PLoS One, Volume 9 (Number 11). Article number e113568. doi:10.1371/journal.pone.0113568 ISSN 1932-6203.
Ruane, Karen M., Lloyd, Adrian J., Fülöp, Vilmos, Dowson, Christopher G., Barreteau, Hélène, Boniface, Audrey, Dementin, Sébastien, Blanot, Didier, Mengin-Lecreulx, Dominique, Gobec, Stanislav, Dessen, Andréa and Roper, David I. (2013) Specificity determinants for lysine incorporation in staphylococcus aureus peptidoglycan as revealed by the structure of a MurE enzyme ternary complex. Journal of Biological Chemistry, Volume 288 (Number 46). Article number 33439. doi:10.1074/jbc.M113.508135 ISSN 0021-9258.
Alderwick, Luke J., Lloyd, Georgina S., Lloyd, Adrian, Lovering, Andrew L., Eggeling, L. and Besra, Gurdyal S. (2011) Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase. Glycobiology, Vol.21 (No.4). pp. 410-425. doi:10.1093/glycob/cwq173 ISSN 1460-2423.
Cressina, Elena, Lloyd, Adrian J., De Pascale, Gianfranco, Mok, B. James, Caddick, Stephen, Roper, David I., Dowson, Christopher G. and Bugg, Tim (2009) Inhibition of tRNA-dependent ligase MurM from Streptococcus pneumoniae by phosphonate and sulfonamide inhibitors. Bioorganic & Medicinal Chemistry, Vol.17 (No.9). pp. 3443-3455. doi:10.1016/j.bmc.2009.03.028 ISSN 0968-0896.
De Pascale, Gianfranco, Lloyd, Adrian J., Schouten, James A., Gilbey, Andrea M., Roper, David I., Dowson, Christopher G. and Bugg, Tim (2008) Kinetic characterization of lipid II-Ala:Alanyl-tRNA ligase (MurN) from streptococcus pneumoniae using semisynthetic aminoacyl-lipid II substrates. Journal of Biological Chemistry, Vol.283 (No.50). pp. 34571-34579. doi:10.1074/jbc.M805807200 ISSN 0021-9258.
This list was generated on Fri Mar 29 05:30:33 2024 GMT.