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Potential hormone mechanisms of bariatric surgery
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Dimitriadis, Georgios K., Randeva, Manpal S. and Miras, Alexander D. (2017) Potential hormone mechanisms of bariatric surgery. Current Obesity Reports, 6 (3). pp. 253-265. doi:10.1007/s13679-017-0276-5 ISSN 2162-4968.
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Official URL: http://doi.org/10.1007/s13679-017-0276-5
Abstract
Purpose of Review
In recent years, the role of the gastrointestinal (GI) tract in energy homeostasis through modulation of the digestion and absorption of carbohydrates and the production of incretin hormones is well recognized.
Recent Findings
Bariatric surgery for obesity has been a very effective method in substantially improving weight, and numerous studies have focused on intestinal adaptation after bariatric procedures. A number of structural and functional changes in the GI tract have been reported postsurgery, which could be responsible for the altered hormonal responses. Furthermore, the change in food absorption rate and the intestinal regions exposed to carbohydrates may affect blood glucose response.
Summary
This review hopes to give new insights into the direct role of gut hormones, by summarising the metabolic effects of bariatric surgery.
Item Type: | Journal Article | ||||||
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Subjects: | R Medicine > RC Internal medicine R Medicine > RD Surgery |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||||
Library of Congress Subject Headings (LCSH): | Obesity -- Surgery, Gastrointestinal hormones, Laparoscopic surgery, Gastrectomy | ||||||
Journal or Publication Title: | Current Obesity Reports | ||||||
Publisher: | Springer | ||||||
ISSN: | 2162-4968 | ||||||
Official Date: | September 2017 | ||||||
Dates: |
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Volume: | 6 | ||||||
Number: | 3 | ||||||
Page Range: | pp. 253-265 | ||||||
DOI: | 10.1007/s13679-017-0276-5 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||
Date of first compliant deposit: | 20 March 2018 | ||||||
Date of first compliant Open Access: | 21 March 2018 | ||||||
Open Access Version: |
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