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Serotonin receptor rnRNA expression in rat dorsal root ganglion neurons
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UNSPECIFIED (2003) Serotonin receptor rnRNA expression in rat dorsal root ganglion neurons. NEUROSCIENCE LETTERS, 337 (3). pp. 119-122. doi:10.1016/S0304-3904(02)01256-9 ISSN 0304-3940.
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Official URL: http://dx.doi.org/10.1016/S0304-3904(02)01256-9
Abstract
In the present study, we have used in situ hybridization to examine the distribution of serotonin (5-HT) receptors in rat dorsal root ganglion (DRG) neurons. Within DRG neurons, mRNAs for 5-HT1B, 5-HT1D, 5-HT2A, 5-HT2B, 5-HT3B and 5-HT4 receptors were readily detected in small (<25 mum), medium (25-45 mum) and large (>45 mum) diameter neurons. In contrast mRNAs for 5-HT1A, 5-HT1E, 5-HT2C, 5-HT5A, 5-HT5B, 5-HT6 and 5-HT7 receptors were undetectable in these neurons. The present study provides an insight into the molecular profile of 5-HT receptor subtypes in neurons responsible for modulating sensory information. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry | ||||
Journal or Publication Title: | NEUROSCIENCE LETTERS | ||||
Publisher: | ELSEVIER SCI IRELAND LTD | ||||
ISSN: | 0304-3940 | ||||
Official Date: | 13 February 2003 | ||||
Dates: |
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Volume: | 337 | ||||
Number: | 3 | ||||
Number of Pages: | 4 | ||||
Page Range: | pp. 119-122 | ||||
DOI: | 10.1016/S0304-3904(02)01256-9 | ||||
Publication Status: | Published |
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