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Data for Millennia of genomic stability within the invasive Para C Lineage of Salmonella enterica: Salmonella supertree 1
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Zhou, Zhemin, Lundstrøm, Inge, Dien, Alicia Tran, Duchêne, Sebastián, Alikhan, Nabil-Fareed, Sergeant, Martin J., Langridge, Gemma, Fotakis, Anna K., Nair, Satheesh, Stenøien, Hans K., Hamre, Stian S., Casjens, Sherwood, Quince, Christopher , Christophersen, Axel, Thomson, Nicholas R., Weill, François-Xavier, Ho, Simon, Gilbert, M. Thomas P. and Achtman, Mark (2018) Data for Millennia of genomic stability within the invasive Para C Lineage of Salmonella enterica: Salmonella supertree 1. [Dataset]
Microsoft Excel (Metadata for 2,964 representative genomes in Salmonella enterica subsp. I. )
Salmonella supertree 1.xlsx - Published Version Available under License Creative Commons Attribution 4.0. Download (405Kb) |
Official URL: http://wrap.warwick.ac.uk/101835
Abstract
Salmonella enterica serovar Paratyphi C is the causative agent of enteric (paratyphoid) fever. While today a potentially lethal infection of humans that occurs in Africa and Asia, early 20th century observations in Eastern Europe suggest it may once have had a wider-ranging impact on human societies. We recovered a draft Paratyphi C genome from the 800-year-old skeleton of a young woman in Trondheim, Norway, who likely died of enteric fever. Analysis of this genome against a new, significantly expanded database of related modern genomes demonstrated that Paratyphi C is descended from the ancestors of swine pathogens, serovars Choleraesuis and Typhisuis, together forming the Para C Lineage. Our results indicate that Paratyphi C has been a pathogen of humans for at least 1,000 years, and may have evolved after zoonotic transfer from swine during the Neolithic period.
Item Type: | Dataset | |||||||||||||||
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Subjects: | Q Science > QR Microbiology | |||||||||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | |||||||||||||||
Type of Data: | Table about barcode name, project id, sample id, run accession, source niche, source type, source details, collection year, collection month, continent, country, lab contact, comment, serovar (submitted metadata), serotype (predicted), ST, eBG, rST, reBG | |||||||||||||||
Library of Congress Subject Headings (LCSH): | Typhoid fever -- Genetic aspects -- History, Typhoid fever -- Trondheim (Norway) -- 13th century | |||||||||||||||
Publisher: | University of Warwick, Warwick Medical School | |||||||||||||||
Official Date: | 4 May 2018 | |||||||||||||||
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Status: | Not Peer Reviewed | |||||||||||||||
Publication Status: | Published | |||||||||||||||
Media of Output (format): | .xlsx | |||||||||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||||||||
Copyright Holders: | University of Warwick | |||||||||||||||
Description: | Metadata for 2,964 representative genomes in Salmonella enterica subsp. I. |
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Date of first compliant deposit: | 2 May 2018 | |||||||||||||||
Date of first compliant Open Access: | 2 May 2018 | |||||||||||||||
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