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Cytological prediction of cervical intraepithelial neoplasia grade 3 : does size of the lesion matter?
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Etherington, L. J., Luesley, D. M., Shafi, M. I., Dunn, Janet A. and Jordan, J. A. (1998) Cytological prediction of cervical intraepithelial neoplasia grade 3 : does size of the lesion matter? Journal of Lower Genital Tract Disease, 2 (1). pp. 17-18. doi:10.1097/00128360-199801000-00004 ISSN 1089-2591.
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Official URL: https://doi.org/10.1097/00128360-199801000-00004
Abstract
Objective:
Our objective was to test the hypothesis that accurate cytological prediction of cervical intraepithelial neoplasia grade 3 (CIN3) is related to the size of the atypical transformation zone.
Patients and Methods:
Data on 340 women in whom CIN3 was diagnosed after large-loop excision of the transformation zone were recorded prospectively on a computerized database. These data were studied with regard to such variables as lesion size, age, parity, contraception use, and smoking status.
Results:
No association was demonstrated between cytological findings and lesion size in accurately predicting CIN3 lesions. A weak association between cytological findings and age was demonstrated: Cytology is more likely to predict CIN3 accurately in women 25 years or older than in women younger than 25 years.
Conclusions:
Accurate cytological prediction of CIN3 is not related to the size of the atypical transformation zone seen at colposcopy. The CIN3 lesions may be present as discrete foci within a background of low-grade changes.
Item Type: | Journal Article | ||||||
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Subjects: | R Medicine > RG Gynecology and obstetrics | ||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Journal of Lower Genital Tract Disease | ||||||
Publisher: | Lippencott Williams & Wilkins | ||||||
ISSN: | 1089-2591 | ||||||
Official Date: | 1998 | ||||||
Dates: |
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Volume: | 2 | ||||||
Number: | 1 | ||||||
Page Range: | pp. 17-18 | ||||||
DOI: | 10.1097/00128360-199801000-00004 | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access |
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