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Diagnostic assessment reviews : is cost-effectiveness analysis helpful or necessary?
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Mistry, Hema and Mason, James (2018) Diagnostic assessment reviews : is cost-effectiveness analysis helpful or necessary? Journal of Health Services Research & Policy, 23 (4). pp. 222-242. doi:10.1177/1355819618787215 ISSN 1355-8196.
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Official URL: http://dx.doi.org/10.1177/1355819618787215
Abstract
Objective
Diagnostic Assessment Reviews are part of the work programme of the National Institute of Health and Care Excellence (NICE) in England to evaluate emergent medical technologies and so ensure timely and consistent adoption within the National Health Service (NHS). New diagnostics have the potential to improve health outcomes and impact positively on health service resource use. This study sought to assess the quality of economic evidence informing Diagnostic Assessment Reviews.
Methods
We reviewed 27 Diagnostic Assessment Reviews that had been published by NICE as of 30 May 2017 by summarizing and interpreting the evidence that was used to carry out cost-effectiveness analyses. Common issues and challenges of the assessment process were illustrated.
Findings
DARs differed in the methods and assumptions used to construct economic models, and linkage of economic model and diagnostic findings. Even though some diagnostic technologies were estimated to be cost-effective, they were not always adopted for routine use in the NHS. The majority of Diagnostic Assessment Review economic models relied heavily on assumptions and expert opinion, with considerable uncertainty about the cost-effectiveness of diagnostic testing.
Conclusions
Diagnostic Assessment Reviews appraisals as commissioned by NICE typically feature varying evidence for diagnostic performance and limited evidence for resource implications and quality of life, often leading to recommendations for further research. Given the process opportunity cost, a two-stage topic selection process, with initial assessment specifying further research and proceeding to full assessment when adequate evidence is available may be more appropriate and help signal to diagnostics companies the type of research evidence required.
Item Type: | Journal Article | ||||||||
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Subjects: | R Medicine > R Medicine (General) | ||||||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | National Institute for Health and Care Excellence (Great Britain), Medical technology -- Evaluation -- Economic aspects | ||||||||
Journal or Publication Title: | Journal of Health Services Research & Policy | ||||||||
Publisher: | Royal Society of Medicine Press Ltd. | ||||||||
ISSN: | 1355-8196 | ||||||||
Official Date: | 1 October 2018 | ||||||||
Dates: |
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Volume: | 23 | ||||||||
Number: | 4 | ||||||||
Page Range: | pp. 222-242 | ||||||||
DOI: | 10.1177/1355819618787215 | ||||||||
Status: | Peer Reviewed | ||||||||
Publication Status: | Published | ||||||||
Reuse Statement (publisher, data, author rights): | Mistry, Hema and Mason, James (2018) Diagnostic assessment reviews : is cost-effectiveness analysis helpful or necessary? Journal of Health Services Research & Policy, 23 (4). pp. 222-242. doi:10.1177/1355819618787215. Copyright © 2018 © SAGE Publications. Reprinted by permission of SAGE Publications. | ||||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||||
Date of first compliant deposit: | 19 October 2018 | ||||||||
Date of first compliant Open Access: | 19 October 2018 | ||||||||
RIOXX Funder/Project Grant: |
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