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On a general theoretical foundation for endocrinology
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Van Den Berg, Hugo (2019) On a general theoretical foundation for endocrinology. Science Progress, 102 (1). pp. 43-60. doi:10.1177/0036850419825926 ISSN 0036-8504.
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Official URL: https://doi.org/10.1177/0036850419825926
Abstract
Hormones are messenger molecules that distribute across all tissues and thus operate on the whole-organism level. Moreover, a given hormone typically affects a number of different biological processes. As such, hormones coordinate concerted cooperation between the cells and tissues of an organism, a phenomenon that has been termed ‘organismal harmony’. Furthermore, a concept that has recently been gaining traction is that hormones mediate or represent life history trade-offs, which are ultimately moulded by evolutionary pressures. Here, this concept is extended to include all ‘decisions’ or ‘choices’ that are made at the organismal level. A formal framework is sketched to explore the proposition that organismal biology, together with the ‘fitness landscape’, suffices in principle to determine minimalistic dynamics of the endocrine system.
| Item Type: | Journal Article | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects: | Q Science > QA Mathematics | ||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Mathematics | ||||||||
| Journal or Publication Title: | Science Progress | ||||||||
| Publisher: | Sage Publications Ltd. | ||||||||
| ISSN: | 0036-8504 | ||||||||
| Official Date: | March 2019 | ||||||||
| Dates: |
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| Volume: | 102 | ||||||||
| Number: | 1 | ||||||||
| Page Range: | pp. 43-60 | ||||||||
| DOI: | 10.1177/0036850419825926 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Reuse Statement (publisher, data, author rights): | Posted ahead of print. Van Den Berg, Hugo (2018) On a general theoretical foundation for endocrinology. Science Progress. Copyright © 2018 The Author. Reprinted by permission of SAGE Publications. https://uk.sagepub.com/en-gb/eur/science-progress/journal203627 | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 17 December 2018 | ||||||||
| Date of first compliant Open Access: | 4 January 2019 | ||||||||
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