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Using histology to evaluate micro-CT findings of trauma in three post-mortem samples — First steps towards method validation
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Baier, Waltraud, Mangham, Chas, Warnett, Jason M., Payne, Mark, Painter, Michelle and Williams, M. A. (2019) Using histology to evaluate micro-CT findings of trauma in three post-mortem samples — First steps towards method validation. Forensic Science International, 297 . pp. 27-34. doi:10.1016/j.forsciint.2019.01.027
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Official URL: https://doi.org/10.1016/j.forsciint.2019.01.027
Abstract
Forensic imaging technology has rapidly advanced over the past several decades and is gaining increasing significance in medico-legal death investigations. Medical-grade computed tomography (CT) is now routinely used in post-mortem examinations at numerous institutions across the globe. However, the resolution of medical-grade CT is limited and unsuitable when used to depict some smaller anatomical structures or micro-trauma. High-resolution micro-CT offers up to 100× the resolution to overcome this problem but is a very recent addition to the field of forensic radiology. Few studies so far have attempted to validate the results which is an essential prerequisite for it to be used in the criminal justice process as demanded by regulatory bodies. This study directly compares micro-CT images with histology, the current gold standard. Three cases were examined: two larynges from suspected strangulations and one ribcage of a case of fatal child abuse. A strong correlation was observed between histology and micro-CT as the majority of skeletal injuries were identified correctly. This paper discusses the forensic implications of the results and how micro-CT is complementary to histology.
| Item Type: | Journal Article | ||||||||
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| Subjects: | H Social Sciences > HV Social pathology. Social and public welfare R Medicine > RA Public aspects of medicine > RA1001 Forensic Medicine. Medical jurisprudence. Legal medicine |
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| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group) | ||||||||
| Library of Congress Subject Headings (LCSH): | Forensic sciences, Tomography, Autopsy, Histology | ||||||||
| Journal or Publication Title: | Forensic Science International | ||||||||
| Publisher: | Elsevier | ||||||||
| Official Date: | April 2019 | ||||||||
| Dates: |
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| Volume: | 297 | ||||||||
| Page Range: | pp. 27-34 | ||||||||
| DOI: | 10.1016/j.forsciint.2019.01.027 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||||
| Date of first compliant deposit: | 10 March 2019 | ||||||||
| Date of first compliant Open Access: | 13 March 2019 | ||||||||
| RIOXX Funder/Project Grant: |
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