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Estimating the incubation period of acute Q fever, a systematic review
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Todkill, Daniel, Fowler, T. and Hawker, J. I. (2018) Estimating the incubation period of acute Q fever, a systematic review. Epidemiology and Infection, 146 (06). pp. 665-672. doi:10.1017/S095026881700303X ISSN 0950-2688.
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Official URL: http://dx.doi.org/10.1017/S095026881700303X
Abstract
Estimates of the incubation period for Q fever vary substantially between different reviews and expert advice documents. We systematically reviewed and quality appraised the literature to provide an evidence-based estimate of the incubation period of the Q fever by the aerosolised infection route. Medline (OVIDSP) and EMBASE were searched with the search limited to human studies and English language. Eligible studies included persons with symptomatic, acute Q fever, and defined exposure to Coxiella burnetti. After review of 7115 titles and abstracts, 320 records were screened at full-text level. Of these, 23 studies contained potentially useful data and were quality assessed, with eight studies (with 403 individual cases where the derivation of incubation period was possible) being of sufficient quality and providing individual-level data to produce a pooled summary. We found a median incubation period of 18 days, with 95% of cases expected to occur between 7 and 32 days after exposure.
Item Type: | Journal Article | ||||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Epidemiology and Infection | ||||||
Publisher: | Cambridge University Press | ||||||
ISSN: | 0950-2688 | ||||||
Official Date: | 21 March 2018 | ||||||
Dates: |
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Volume: | 146 | ||||||
Number: | 06 | ||||||
Page Range: | pp. 665-672 | ||||||
DOI: | 10.1017/S095026881700303X | ||||||
Status: | Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Access rights to Published version: | Restricted or Subscription Access |
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