Bisset, Alexander A., Dishington, Allan, Jones, Teyrnon C., Clarkson, Guy J. and Wills, Martin (2019) Data for Synthesis and reduction reactions of pyridones and 5-acyl-2-methoxypyridines. [Dataset]
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Abstract
The synthesis of a series of pyridones, from their 2-hydroxypyridine or 2-methoxypyridine precursors, is described, along with studies into their reductions to saturated heterocycles. A number of 5-acylpyridones were prepared and were evaluated as substrates for asymmetric transfer hydrogenation prior to conversion to saturated heterocycles. The enantioselective reduction of 5-acetyl-1-benzylpyrimidine-2,4(1H,3H)-dione is also described.
| Item Type: | Dataset |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry |
| Type of Data: | Experimental data |
| Library of Congress Subject Headings (LCSH): | Organic compounds -- Synthesis, Hydroxypyridones -- Sythesis |
| Publisher: | University of Warwick, Department of Chemistry |
| Official Date: | 26 March 2019 |
| Dates: | Date Event 26 March 2019 Published |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Open Access (Creative Commons open licence) |
| Copyright Holders: | University of Warwick |
| Description: | Supplemental information underpinning publication |
| Date of first compliant deposit: | 28 December 2015 |
| Date of first compliant Open Access: | 28 December 2015 |
| Funder: | Engineering and Physical Sciences Research Council (EPSRC), AstraZeneca (Firm) |
| RIOXX Funder/Project Grant: | Project/Grant ID RIOXX Funder Name Funder ID UNSPECIFIED [EPSRC] Engineering and Physical Sciences Research Council |
| Related URLs: | |
| Contributors: | Contribution Name Contributor ID Depositor Wills, Martin 35981 |
| URI: | https://wrap.warwick.ac.uk/116584/ |
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