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Diverse profiles of anxiety related disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi syndromes
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Crawford, Hayley, Waite, Jane and Oliver, Chris (2017) Diverse profiles of anxiety related disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi syndromes. Journal of Autism and Developmental Disorders, 47 (12). pp. 3728-3740. doi:10.1007/s10803-016-3015-y ISSN 0162-3257.
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WRAP-diverse-profiles-anxiety-related-disorders-fragilex-cornelia-de-Lange-rubinstein–taybi-syndromes-Crawford-2017.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1066Kb) | Preview |
Official URL: http://dx.doi.org/10.1007/s10803-016-3015-y
Abstract
Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein–Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive–compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive–compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive–compulsive subscales. The results highlight divergent profiles of anxiety symptomatology between these groups.
| Item Type: | Journal Article | ||||||
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| Subjects: | B Philosophy. Psychology. Religion > BF Psychology H Social Sciences > HV Social pathology. Social and public welfare Q Science > QM Human anatomy R Medicine > RB Pathology R Medicine > RC Internal medicine R Medicine > RG Gynecology and obstetrics R Medicine > RJ Pediatrics |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Anxiety, Anxiety disorders, Anxiety in children, Genetic disorders, Fragile X syndrome, Intellectual disability, De Lange's syndrome, Abnormalities, Human | ||||||
| Journal or Publication Title: | Journal of Autism and Developmental Disorders | ||||||
| Publisher: | Springer | ||||||
| ISSN: | 0162-3257 | ||||||
| Official Date: | 31 January 2017 | ||||||
| Dates: |
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| Volume: | 47 | ||||||
| Number: | 12 | ||||||
| Page Range: | pp. 3728-3740 | ||||||
| DOI: | 10.1007/s10803-016-3015-y | ||||||
| Status: | Peer Reviewed | ||||||
| Publication Status: | Published | ||||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||||
| Date of first compliant deposit: | 24 January 2020 | ||||||
| Date of first compliant Open Access: | 24 January 2020 | ||||||
| RIOXX Funder/Project Grant: |
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