
The Library
Role of ovum in reproductive outcomes
Tools
Jeve, Yadava B. (2018) Role of ovum in reproductive outcomes. PhD thesis, University of Warwick.
|
PDF
WRAP_Theses_Jeve_2018.pdf - Submitted Version - Requires a PDF viewer. Download (17Mb) | Preview |
Official URL: http://webcat.warwick.ac.uk/record=b3453478~S15
Abstract
The ovary is one of the most dynamic organs in the human body. Ovaries have a finite pool of follicles during fetal life. On-going follicular atresia significantly contributes to a quantitative and qualitative decline in ovarian reserve. Only a tiny number of follicles are released between puberty and menopause in the form of ovulation. Reproductive outcome following assisted conception significantly depends upon the quality and quantity of oocytes. Ovarian reserve is a significant predictor of ovarian response during the assisted conception treatment cycle. It not only determines the number of oocytes to be collected but also controls the pregnancy outcome. The first two publications evaluate the prediction of ovarian reserve and management of the poor ovarian reserve. The third and fourth publications analyse use of donor oocyte as a treatment option and the pregnancy complications associated with donor oocyte. The fifth publication examines the factors affecting fertilisation rates in assisted conception and strategies to improve the fertilisation process. Poor quality oocytes and the resultant poor-quality embryo is one of the primary causes for miscarriage in natural and assisted conception. The sixth and seventh publications discuss the diagnosis and management of miscarriages. These publications have significant clinical and research implications which are discussed in results and discussion chapter. Especially sixth publication contributed to changing the national guideline on the diagnosis of missed miscarriage. Recent research updates that occurred after our research period are discussed in a separate chapter. Further research is required to manage the reproductive outcomes related to the poor quantity and quality of oocytes.
Item Type: | Thesis (PhD) | ||||
---|---|---|---|---|---|
Subjects: | Q Science > QL Zoology Q Science > QM Human anatomy Q Science > QP Physiology R Medicine > RG Gynecology and obstetrics |
||||
Library of Congress Subject Headings (LCSH): | Ovum, Ovarian atresia, Fetus, Puberty, Menopause, Ovulation | ||||
Official Date: | September 2018 | ||||
Dates: |
|
||||
Institution: | University of Warwick | ||||
Theses Department: | Warwick Medical School | ||||
Thesis Type: | PhD | ||||
Publication Status: | Unpublished | ||||
Supervisor(s)/Advisor: | Sutcliffe, Paul ; Tan, Bee | ||||
Format of File: | |||||
Extent: | 61, 10, 5, 1, 262, 81, 158, 10, 19, 496, 169 leaves: illustrations, charts, plates | ||||
Language: | eng |
Request changes or add full text files to a record
Repository staff actions (login required)
![]() |
View Item |
Downloads
Downloads per month over past year