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Glycosidase-catalysed synthesis of alpha-galactosyl epitopes important in xenotransplantation and toxin binding using the alpha-galactosidase from Penicillium multicolor
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UNSPECIFIED (1999) Glycosidase-catalysed synthesis of alpha-galactosyl epitopes important in xenotransplantation and toxin binding using the alpha-galactosidase from Penicillium multicolor. CHEMICAL COMMUNICATIONS (20). pp. 2065-2066. ISSN 1359-7345.
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Abstract
The alpha-galactosidase from Penicillium multicolor catalyses highly regioselective galactosyl transfer on to mono- and di-saccharide acceptors that have a non-reducing terminal galactose unit to give products containing the alpha-D-Galp-(1 --> 3)-D-Galp epitope found on pig tissue and which is responsible for the hyperacute rejection response in xenotransplantation of pig organs into man.
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Journal or Publication Title: | CHEMICAL COMMUNICATIONS | ||||
Publisher: | ROYAL SOC CHEMISTRY | ||||
ISSN: | 1359-7345 | ||||
Official Date: | 21 October 1999 | ||||
Dates: |
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Number: | 20 | ||||
Number of Pages: | 2 | ||||
Page Range: | pp. 2065-2066 | ||||
Publication Status: | Published |
Data sourced from Thomson Reuters' Web of Knowledge
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