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Cohort profile : Oxford Pain, Activity and Lifestyle (OPAL) Study, a prospective cohort study of older adults in England

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Sanchez Santos, Maria, Williamson, Esther, Bruce, Julie, Ward, Lesley, Mallen, Christian D., Garrett, Angela, Morris, Alana and Lamb, Sarah E. (2020) Cohort profile : Oxford Pain, Activity and Lifestyle (OPAL) Study, a prospective cohort study of older adults in England. BMJ Open, 10 (9). e037516. doi:10.1136/bmjopen-2020-037516 ISSN 2044-6055.

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Official URL: https://bmjopen.bmj.com/content/10/9/e037516

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Abstract

Purpose: The ‘Oxford Pain, Activity and Lifestyle’ (OPAL) Cohort is a longitudinal, prospective cohort study of adults, aged 65 years and older, living in the community which is investigating the determinants of health in later life. Our focus was on musculoskeletal pain and mobility, but the cohort is designed with flexibility to include new elements over time. This paper describes the study design, data collection and baseline characteristics of participants. We also compared the OPAL baseline characteristics with nationally representative data sources.

Participants: We randomly selected eligible participants from two stratified age bands (65–74 and 75 and over years). In total, 5409 individuals (42.1% of eligible participants) from 35 general practices in England agreed to participate between 2016 and 2018. The majority of participants (n=5367) also consented for research team to access their UK National Health Service (NHS) Digital and primary healthcare records.

Findings: to date Mean participant age was 74.9 years (range 65–100); 51.5% (n=2784/5409) were women. 94.9% of participants were white, and 28.8% lived alone. Over 83.0% reported pain in at least one body area in the previous 6 weeks. Musculoskeletal symptoms were more prevalent in women (86.4%). One-third of participants reported having one or more falls in the last year. Most participants were confident in their ability to walk outside. The characteristics of OPAL Cohort participants were broadly similar to the general population of the same age.

Future plans: Postal follow-up of the cohort is being undertaken at annual intervals, with data collection ongoing. Linkage to NHS hospital admission data is planned. This English prospective cohort offers a large and rich resource for research on the longitudinal associations between demographic, clinical, and social factors and health trajectories and outcomes in community-dwelling older people.

Item Type: Journal Article
Subjects: H Social Sciences > HV Social pathology. Social and public welfare
R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RB Pathology
R Medicine > RD Surgery
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Older people -- Medical care, Pain in old age -- Treatment, Older people -- Rehabilitation, Movement disorders in old age, Posture disorders -- Age factors
Journal or Publication Title: BMJ Open
Publisher: BMJ
ISSN: 2044-6055
Official Date: 3 September 2020
Dates:
DateEvent
3 September 2020Published
3 September 2020Available
17 July 2020Accepted
Volume: 10
Number: 9
Article Number: e037516
DOI: 10.1136/bmjopen-2020-037516
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 23 October 2020
Date of first compliant Open Access: 27 October 2020
RIOXX Funder/Project Grant:
Project/Grant IDRIOXX Funder NameFunder ID
PTC-RP-PG-0213-20002[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
NIHR-RP-2014-04-026[NIHR] National Institute for Health Researchhttp://dx.doi.org/10.13039/501100000272
UNSPECIFIEDUniversity Hospitals Coventry and Warwickshire NHS Trusthttp://viaf.org/viaf/152707181
Is Part Of: 1
Open Access Version:
  • Publisher
Contributors:
ContributionNameContributor ID
Research GroupOPAL study team, UNSPECIFIED

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