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Erythroderma (exfoliative dermatitis) part one : underlying causes, clinical presentation and pathogenesis
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Tso, Simon, Satchwell, F., Moiz, Haseeb, Tushar, H., Forbat, E., Dhariwal, S., Barlow, R., Kwok, M., Tso, A., Tan, Y. T., Thind, C., Randeva, Harpal S., Barber, T. M. and Ilchyshyn, A. (2021) Erythroderma (exfoliative dermatitis) part one : underlying causes, clinical presentation and pathogenesis. Clinical and Experimental Dermatology, 46 (6). pp. 1001-1010. doi:10.1111/ced.14625 ISSN 0307-6938.
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Official URL: https://doi.org/10.1111/ced.14625
Abstract
Erythroderma (exfoliative dermatitis), first described by Von Hebra in 1868, manifests as a cutaneous inflammatory state, with associated skin barrier and metabolic dysfunctions. The annual incidence of erythroderma is estimated to be 1 to 2 persons per 100,000 population in Europe with a higher male‐to‐female ratio. Erythroderma may present at birth, develop acutely or insidiously (due to progression of an underlying primary pathology, including malignancy). Whilst there is a broad range of diseases that associate with erythroderma, the vast majority of cases result from pre‐existing and chronic dermatoses. In part one of this two part concise review, we explore the underlying causes, clinical presentation, pathogenesis and investigation of erythroderma, and suggest potential treatment targets for erythroderma with unknown causes.
| Item Type: | Journal Article | ||||||||
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| Subjects: | R Medicine > RL Dermatology | ||||||||
| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Acrodynia, Contact dermatitis , Dermatology, Skin -- Diseases , Skin -- Inflammation | ||||||||
| Journal or Publication Title: | Clinical and Experimental Dermatology | ||||||||
| Publisher: | Wiley-Blackwell Publishing Ltd. | ||||||||
| ISSN: | 0307-6938 | ||||||||
| Official Date: | August 2021 | ||||||||
| Dates: |
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| Volume: | 46 | ||||||||
| Number: | 6 | ||||||||
| Page Range: | pp. 1001-1010 | ||||||||
| DOI: | 10.1111/ced.14625 | ||||||||
| Status: | Peer Reviewed | ||||||||
| Publication Status: | Published | ||||||||
| Reuse Statement (publisher, data, author rights): | "This is the peer reviewed version of the following article: Tso, S., Satchwell, F., Moiz, H., Tushar, H., Dhariwal, S., Barlow, R., Forbat, E., Randeva, H., Tan, Y., Ilchyshyn, A., Kwok, M., Barber, T., Thind, C. and Tso, A. (2021), Erythroderma (exfoliative dermatitis) part one: underlying causes, clinical presentation and pathogenesis. Clinical and Experimental Dermatology, which has been published in final form at https://doi.org/10.1111/ced.14625. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions." | ||||||||
| Access rights to Published version: | Restricted or Subscription Access | ||||||||
| Date of first compliant deposit: | 30 April 2021 | ||||||||
| Date of first compliant Open Access: | 27 February 2022 | ||||||||
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