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Erythroderma (exfoliative dermatitis) part one : underlying causes, clinical presentation and pathogenesis

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Tso, Simon, Satchwell, F., Moiz, Haseeb, Tushar, H., Forbat, E., Dhariwal, S., Barlow, R., Kwok, M., Tso, A., Tan, Y. T., Thind, C., Randeva, Harpal S., Barber, T. M. and Ilchyshyn, A. (2021) Erythroderma (exfoliative dermatitis) part one : underlying causes, clinical presentation and pathogenesis. Clinical and Experimental Dermatology, 46 (6). pp. 1001-1010. doi:10.1111/ced.14625 ISSN 0307-6938.

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Official URL: https://doi.org/10.1111/ced.14625

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Abstract

Erythroderma (exfoliative dermatitis), first described by Von Hebra in 1868, manifests as a cutaneous inflammatory state, with associated skin barrier and metabolic dysfunctions. The annual incidence of erythroderma is estimated to be 1 to 2 persons per 100,000 population in Europe with a higher male‐to‐female ratio. Erythroderma may present at birth, develop acutely or insidiously (due to progression of an underlying primary pathology, including malignancy). Whilst there is a broad range of diseases that associate with erythroderma, the vast majority of cases result from pre‐existing and chronic dermatoses. In part one of this two part concise review, we explore the underlying causes, clinical presentation, pathogenesis and investigation of erythroderma, and suggest potential treatment targets for erythroderma with unknown causes.

Item Type: Journal Article
Subjects: R Medicine > RL Dermatology
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016)
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Acrodynia, Contact dermatitis , Dermatology, Skin -- Diseases , Skin -- Inflammation
Journal or Publication Title: Clinical and Experimental Dermatology
Publisher: Wiley-Blackwell Publishing Ltd.
ISSN: 0307-6938
Official Date: August 2021
Dates:
DateEvent
August 2021Published
27 February 2021Available
22 February 2021Accepted
Volume: 46
Number: 6
Page Range: pp. 1001-1010
DOI: 10.1111/ced.14625
Status: Peer Reviewed
Publication Status: Published
Reuse Statement (publisher, data, author rights): "This is the peer reviewed version of the following article: Tso, S., Satchwell, F., Moiz, H., Tushar, H., Dhariwal, S., Barlow, R., Forbat, E., Randeva, H., Tan, Y., Ilchyshyn, A., Kwok, M., Barber, T., Thind, C. and Tso, A. (2021), Erythroderma (exfoliative dermatitis) part one: underlying causes, clinical presentation and pathogenesis. Clinical and Experimental Dermatology, which has been published in final form at https://doi.org/10.1111/ced.14625. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions."
Access rights to Published version: Restricted or Subscription Access
Date of first compliant deposit: 30 April 2021
Date of first compliant Open Access: 27 February 2022
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