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Data for Coevolution fails to maintain genetic variation in a host-parasite model with constant finite population size
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MacPherson, Ailene, Keeling, Matthew James and Otto, Sarah (2021) Data for Coevolution fails to maintain genetic variation in a host-parasite model with constant finite population size. [Dataset]
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Official URL: http://doi.org/10.5061/dryad.m37pvmd0z
Abstract
Coevolutionary negative frequency-dependent selection has been hypothesized to maintain genetic variation in host and parasites.
Despite the extensive literature pertaining to host-parasite coevolution, the dynamics of genetic variation has not been examined in a matching-alleles model (MAM) with a finite population size relative to the expectation under neutral genetic drift alone. The dynamics of the MA coevolution in an infinite population, in fact, suggests that genetic variation in these coevolving populations behaves neutrally. By comparing host heterozygosity to the expectation in a single-species model of neutral genetic drift we find that while this is also largely true in finite populations two additional phenomena arise. First, reciprocal natural selection acting on stochastic perturbations in host and pathogen allele frequencies results in a slight increase or decrease in genetic variation depending on the parameter conditions. Second, following the fixation of an allele in the parasite, selection in the MAM becomes directional, which then rapidly erodes genetic variation in the host. Hence, rather than maintain it, we find that, on average, matching-alleles coevolution depletes genetic variation.
Item Type: | Dataset | ||||||
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Subjects: | Q Science > QH Natural history | ||||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) Faculty of Science, Engineering and Medicine > Science > Mathematics |
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Type of Data: | Experimental data | ||||||
Library of Congress Subject Headings (LCSH): | Coevolution, Variation (Biology), Host-parasite relationships -- Genetic aspects | ||||||
Publisher: | University of Warwick, Mathematics Institute ; University of Warwick, School of Life Sciences | ||||||
Official Date: | 10 March 2021 | ||||||
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Status: | Not Peer Reviewed | ||||||
Publication Status: | Published | ||||||
Media of Output (format): | .cdf .nb .pdf | ||||||
Access rights to Published version: | Open Access (Creative Commons) | ||||||
Copyright Holders: | University of Warwick | ||||||
Description: | Data record consists of zip archives, raw data in cdf and nb format, PDF model diagrams and an accompanying readme file. Mathematica notebooks for model analysis and individual-based simulations run in C++. Further information on specific models and data can be found in the accompanying readme file. |
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