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Clinical characteristics of pneumonia patients of long course of illness infected with SARS-CoV-2
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Chunli, Wang, Liya, Huang, Weiwei, Lu, Guoxi, Chen, Yuyang, Cai, Xiaopan, Li, Xing, Lan, Yaling, Wang, Xiaoqin, Deng, Guangwang, Zeng, Lin, Wang, Chen, Ji, Hai, Huang and Ling, Yang (2022) Clinical characteristics of pneumonia patients of long course of illness infected with SARS-CoV-2. Open Medicine, 17 (1). pp. 947-954. doi:10.1515/med-2022-0465 ISSN 2391-5463.
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WRAP-Clinical-characteristics-of-pneumonia-patients-of-long-course-of-illness-infected-with-SARS-CoV-2-Chen-22.pdf - Published Version - Requires a PDF viewer. Available under License Creative Commons Attribution 4.0. Download (1137Kb) | Preview |
Official URL: http://dx.doi.org/10.1515/med-2022-0465
Abstract
Epidemiological and clinical characteristics of patients with COVID-19 have been reported in the last two years. A few studies reported clinical course of illness of median 22 days, including viral shedding of median 20 days, but there are several cases with a longer time of viral shedding. In this study, we included four cases with a longer illness course of more than 40 days who had been discharged or still in hospital by March 15, 2020. Demographic, clinical treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records. We described the epidemiological and clinical characteristics and the course of viral shedding. Two patients had comorbidity, one with hypertension and the other with diabetes. We found smoking was not an independent risk factor. D-dimer maybe related to the severity of illness but not to the course of the illness. Nucleic acid detection suggested that maybe more sampling sites represented more virus replication sites and longer course of illness. In this study we found some non-critical severe relatively young patients whose character was different from former studies described to provide a basis for reference to assess the risk of transmission and the isolation duration of patients.
Item Type: | Journal Article | |||||||||
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Subjects: | R Medicine > RA Public aspects of medicine R Medicine > RC Internal medicine |
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Clinical Trials Unit Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | COVID-19 (Disease) , COVID-19 (Disease) -- Epidemiology, COVID-19 (Disease) -- Patients -- Health risk assessment , Pneumonia -- Patients -- Health risk assessment | |||||||||
Journal or Publication Title: | Open Medicine | |||||||||
Publisher: | De Gruyter | |||||||||
ISSN: | 2391-5463 | |||||||||
Official Date: | 18 May 2022 | |||||||||
Dates: |
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Volume: | 17 | |||||||||
Number: | 1 | |||||||||
Page Range: | pp. 947-954 | |||||||||
DOI: | 10.1515/med-2022-0465 | |||||||||
Status: | Peer Reviewed | |||||||||
Publication Status: | Published | |||||||||
Access rights to Published version: | Open Access (Creative Commons) | |||||||||
Date of first compliant deposit: | 4 July 2022 | |||||||||
Date of first compliant Open Access: | 5 July 2022 | |||||||||
RIOXX Funder/Project Grant: |
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