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Feeding association between the nucleus of the solitary tract and the ventral tegmental area
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Kim, Eun-Mee, Quinn, Joseph G., Spanswick, David and O'Hare, Eugene (2009) Feeding association between the nucleus of the solitary tract and the ventral tegmental area. Appetite, Vol.53 (No.3). pp. 457-460. doi:10.1016/j.appet.2009.09.003 ISSN 0195-6663.
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Official URL: http://dx.doi.org/10.1016/j.appet.2009.09.003
Abstract
Male Sprague-Dawley rats were fitted with two cannulae in the VTA and one cannula in the NTS for co-administration of the mu-opioid receptoragonist DAMGO in one site and the opioid antagonist naltrexone in the other. Injection of DAMGO into the VTA or the NTS stimulated feeding. The increase in food intake after DAMGO injection into the VTA was decreased following injection of naltrexone into the NTS. Furthermore, the increase in food intake after DAMGO injection into the NTS was decreased following injection of naltrexone into the VTA. These results suggest an opioid-mediated feeding association between the VTA and NTS. (C) 2009 Elsevier Ltd. All rights reserved.
| Item Type: | Journal Article | ||||
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| Subjects: | B Philosophy. Psychology. Religion > BF Psychology R Medicine > RA Public aspects of medicine |
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| Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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| Journal or Publication Title: | Appetite | ||||
| Publisher: | Elsevier BV | ||||
| ISSN: | 0195-6663 | ||||
| Official Date: | December 2009 | ||||
| Dates: |
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| Volume: | Vol.53 | ||||
| Number: | No.3 | ||||
| Number of Pages: | 4 | ||||
| Page Range: | pp. 457-460 | ||||
| DOI: | 10.1016/j.appet.2009.09.003 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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